Cardiovascular And Metabolic Disease

Author : Chaya Gopalan,Erik Kirk
Publisher : Academic Press
Page : 268 pages
File Size : 47,6 Mb
Release : 2022-01-11
Category : Medical
ISBN : 9780128234228

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Biology of Cardiovascular and Metabolic Diseases by Chaya Gopalan,Erik Kirk Pdf

Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases with health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure and way to treat underlying conditions. Focuses succinctly on the physiology and pathophysiology of cardiovascular and metabolic diseases Written in a concise and easy to read manner, allowing readers to quickly understand concepts Highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure

Author : Philip Peplow,James Adams,Tim Young
Publisher : Royal Society of Chemistry
Page : 396 pages
File Size : 54,5 Mb
Release : 2015-05-22
Category : Medical
ISBN : 9781782620464

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Cardiovascular and Metabolic Disease by Philip Peplow,James Adams,Tim Young Pdf

Cardiovascular and metabolic diseases remain the number one cause of death in developed countries and their prevalence is increasing rapidly in developing nations. This book brings together the recent information on these disorders and the links that exist between them in order to provide a complete picture of drug discovery for these conditions. The main three sections comprehensively discuss obesity, hypertension and cardiovascular disease, and diabetes in turn, following an introduction to the molecular links between them. The final chapter provides perspectives on future directions of the field. Chapters are contributed by leaders in the field from academia and industry and cover biomarkers, risk factors, gene-environment interactions, therapies and the various types of animal models that have been used to study each disease. Case studies describing the implementation of animal models in drug development further enhance the book’s usefulness as a comprehensive guide to this important therapeutic area. Providing a full picture of the various types of animal models that have been used to study obesity, hypertension, and insulin resistance with recent case studies, this book provides a valuable resource for medicinal chemists and clinicians working in these disease areas.

Author : Peter Kokkinos,Christina N. Katsagoni,Labros S. Sidossis
Publisher : John Wiley & Sons
Page : 421 pages
File Size : 51,7 Mb
Release : 2023-04-24
Category : Medical
ISBN : 9781119833444

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Prevention and Management of Cardiovascular and Metabolic Disease by Peter Kokkinos,Christina N. Katsagoni,Labros S. Sidossis Pdf

Prevention and Management of Cardiovascular and Metabolic Disease Provides accurate and well-documented information on the impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases and healthy aging. This authoritative textbook examines the independent and combined impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases, with special emphasis on the elderly populations. In this book the authors: Provide the latest data on the association between a suboptimal diet and physical inactivity and chronic disease. Examine the role of epigenetics on longevity. Discuss the fundamentals of healthy aging. Highlight the role of well-known dietary patterns such as the Mediterranean diet and the Nordic diet in favorable health outcomes, including cardiovascular, metabolic health, and healthy aging. Discuss the health outcomes of physical activity and healthy aging. Present the most recent evidence-based data on the independent and synergistic impact of diet and exercise on disease prevention and management including, heart disease, diabetes mellitus, hypertension, dyslipidemia, kidney failure, cancer and other conditions. Prevention and Management of Cardiovascular and Metabolic Disease: Diet, Physical Activity and Healthy Aging is an excellent textbook for upper-level undergraduate and graduate students in medical and health-related disciplines and for health professionals, including dietitians and nutritionists, exercise physiologists, athletic trainers, nurses, physicians, geriatricians, and other health professionals with a special focus in older adults. This book is also a highly useful reference for health professionals interested in introducing diet and physical activity as an intervention for healthy aging as well as the prevention and management of cardiovascular and other metabolic diseases that are prevalent in aging populations.

Author : Robert H. Eckel
Publisher : John Wiley & Sons
Page : 238 pages
File Size : 49,8 Mb
Release : 2011-07-05
Category : Medical
ISBN : 9781444347784

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Metabolic Risk for Cardiovascular Disease by Robert H. Eckel Pdf

The relationship of metabolic diseases to cardiovascular disease (CVD) is reaching epidemic proportions. This relates mostly to the increasing prevalence of obesity, the metabolic syndrome and type 2 diabetes. This book outlines and addresses the metabolic factors and related diseases that contribute to CVD, including brief introductions to metabolic pathways including lipid and lipoprotein metabolism, macronutrient fuel partitioning, insulin action and body weight regulation. Mechanisms that relate to becoming obese, maintenance of the obese state, the dyslipidemias, and glucose intolerance/diabetes are also addressed, and the importance of interventions that reduce metabolic risk factors and CVD are covered.

Author : Andrew J. Krentz,Nathan D. Wong
Publisher : CRC Press
Page : 340 pages
File Size : 54,9 Mb
Release : 2006-11-08
Category : Medical
ISBN : 9781420020601

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Metabolic Syndrome and Cardiovascular Disease by Andrew J. Krentz,Nathan D. Wong Pdf

Addressing a topic of utmost importance in the field, this text addresses the epidemiology, diagnosis, assessment, and management of patients with metabolic syndrome-focusing on implications for cardiovascular disease risk. With an abundance of clearly organized tables, flowcharts, and practice guidelines, this blue-ribbon source succinctly analyze

Author : Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent
Publisher : World Bank Publications
Page : 466 pages
File Size : 51,6 Mb
Release : 2017-11-17
Category : Medical
ISBN : 9781464805202

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Disease Control Priorities, Third Edition (Volume 5) by Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent Pdf

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Author : T. Barry Levine,Arlene Bradley Levine
Publisher : John Wiley & Sons
Page : 967 pages
File Size : 47,9 Mb
Release : 2012-07-05
Category : Medical
ISBN : 9781118480076

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Metabolic Syndrome and Cardiovascular Disease by T. Barry Levine,Arlene Bradley Levine Pdf

Trends indicate that the metabolic syndrome will become the leading risk factor for heart disease. Now more than ever you need an all-in-one reference that provides the tools and practical advice you need to: Identify at-risk patients Explain individual contributing factors Aid in patient education and motivation Direct comprehensive care and Choose the most appropriate interventions Comprehensively revised to reflect leading-edge research and now organized to facilitate easy access to essential information and clinically-relevant guidance, Metabolic Syndrome and Cardiovascular Disease, 2e offers this and more. Not only will you receive a solid understanding of the pathophysiology underlying the metabolic syndrome and cardiovascular disease but also the rationale for today’s most effective treatments. What’s new? Filled with timely new content, this updated edition covers: New discoveries that have changed our understanding of the pathogenesis and interrelationship of metabolic syndrome, cardiovascular disease (CHD), and type 2 diabetes mellitus (DM) The relevance of mitochondria and telomeres Sleep and its impact on cardiometabolic health The pivotal interplay between insulin and forkhead transcriptionfactors Calorie restriction research Bariatric surgery experiences and outcomes In addition, each chapter includes essential information on comorbidities, interventions, and pharmacotherapeutic options – an exclusive feature found only in the second edition!

Author : Mario Mancini,Jose M. Ordovas,Gabrielle Riccardi,Paolo Rubba,Pasquale Strazzullo
Publisher : John Wiley & Sons
Page : 589 pages
File Size : 46,7 Mb
Release : 2011-07-11
Category : Medical
ISBN : 9781444347883

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Nutritional and Metabolic Bases of Cardiovascular Disease by Mario Mancini,Jose M. Ordovas,Gabrielle Riccardi,Paolo Rubba,Pasquale Strazzullo Pdf

Extraordinary advances in the understanding of the links between nutrition, metabolism, and cardiovascular disease have prompted a systematic reappraisal of knowledge in the field. As a result, it is now imperative that clinicians who care for patients with CVD or its key risk factors have a solid understanding of the often complex interrelationships between cardiovascular health and chronic diseases such as diabetes and obesity. Written by a team of international thought leaders in cardiology, endocrinology, diabetology and nutritional science, this important new book: Examines and updates the role of obesity, hyperlipidemia, diabetes, hypertension, thrombosis, and aging in atherogenesis Describes in detail the scientific and clinical evidence of the etiopathogenesis of ischemic heart disease as well as of peripheral and cerebrovascular disease Focuses on the 6 topics that will be of greatest interest to readers: 1) general nutrition, 2) metabolic syndrome and diabetes, 3) hyperlipidemia and atherosclerosis, 4) hypertension and cerebrovascular disease, 5) hemostasis and thrombosis, 6) aging Throughout the book, in clear and accessible text, contributors illuminate the close relationship between dietary habits, the metabolic processes of nutrients, and their impact on the cardiovascular system, always with an eye on how the physician can use this information to implement better cardiovascular prevention and improve patient care. Nutritional and Metabolic Bases of Cardiovascular Disease is ideal for those who need to update their knowledge of the links between nutrition, metabolism and CVD, from trainees, clinicians and clinical investigators in cardiovascular medicine to endocrinologists, diabetologists, and nutritionists.

Author : H. Böhles,A. C. Sewell
Publisher : CRC Press
Page : 188 pages
File Size : 48,7 Mb
Release : 2004
Category : Cardiomyopathy
ISBN : 3887631048

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Metabolic Cardiomyopathy by H. Böhles,A. C. Sewell Pdf

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Author : Gary D. Lopaschuk,Naranjan S. Dhalla
Publisher : Springer
Page : 295 pages
File Size : 51,6 Mb
Release : 2014-08-22
Category : Science
ISBN : 9781493912278

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Cardiac Energy Metabolism in Health and Disease by Gary D. Lopaschuk,Naranjan S. Dhalla Pdf

The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Author : Anonim
Publisher : Unknown
Page : 488 pages
File Size : 46,6 Mb
Release : 2006
Category : Cardiovascular system
ISBN : 9758967673

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Metabolic Syndrome and Cardiovascular Disease by Anonim Pdf

Explores the underlying mechanisms of insulin resistance and the metabolic syndrome as they relate to coronary heart disease, heart failure, hypertension, and secondary cardiovascular problems. Combines theory with practice in meaningful applications that detail how to manage your at-risk patients. Provides the help needed to formulate rational therapeutic interventions that will effectively prevent or mitigate the manifestations of the conditions that have emerged as key precursors to cardiovascular disease.

Author : Xiaoqiang Tang,Md. Shenuarin Bhuiyan,InKyeom Kim
Publisher : Frontiers Media SA
Page : 219 pages
File Size : 51,7 Mb
Release : 2021-12-06
Category : Science
ISBN : 9782889718139

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Metabolic Regulation in the Development of Cardiovascular Diseases by Xiaoqiang Tang,Md. Shenuarin Bhuiyan,InKyeom Kim Pdf

Author : Enrique Z. Fisman,Alexander Tenenbaum
Publisher : Karger Medical and Scientific Publishers
Page : 189 pages
File Size : 43,9 Mb
Release : 2008-01-01
Category : Medical
ISBN : 9783805584272

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Cardiovascular Diabetology by Enrique Z. Fisman,Alexander Tenenbaum Pdf

The prevalence of obesity, metabolic syndrome and diabetes - three links of the same 'atherothrombotic chain' - has reached pandemic proportions worldwide. As a result, our civilization is at war against a threatening enemy: cardio-diabetes. Several independent physiological processes underlie the clustering of cardio-diabetes, including central obesity, insulin resistance, dyslipidemia, inflammation, impaired glucose tolerance, and hypertension. Early detection is of overwhelming importance for public health. The complex and intimate relationship between cardiovascular disease and diabetes from basic science to clinical and therapeutic concerns is discussed in this outstanding book. Beginning with molecular, biochemical, inflammatory and cellular aspects, this publication continues with histological and pathophysiological issues, details particular problems in specific metabolic and clinical settings, and finally analyzes several aspects of clinical pharmacology focusing on the optimal management of combined dyslipidemia and non-insulin antidiabetic therapy in cardiac diabetic patients. This book will be a gain in knowledge for every cardiologist, diabetologist, specialist in internal medicine, nutritionalist, general physician and medical student.

Author : Michael Schwarzer,Torsten Doenst
Publisher : Academic Press
Page : 240 pages
File Size : 55,7 Mb
Release : 2015-11-04
Category : Medical
ISBN : 9780128026144

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The Scientist's Guide to Cardiac Metabolism by Michael Schwarzer,Torsten Doenst Pdf

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field

Author : Andrew J. Krentz,Robert J. Chilton
Publisher : Academic Press
Page : 531 pages
File Size : 41,6 Mb
Release : 2023-03-28
Category : Medical
ISBN : 9780323983181

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Cardiovascular Endocrinology and Metabolism by Andrew J. Krentz,Robert J. Chilton Pdf

Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine discusses the close intersection between metabolic disorders and cardiovascular disease, covering the basic science and pathophysiology of disease and the latest research in pharmacological approaches and translational therapeutic options. This book is a valuable resource for the vascular and endocrinology clinical and research communities in need of knowledge and potential outcomes. The global increase in the prevalence of cardiometabolic disorders, and the introduction of therapeutic options for treating metabolic disease that also lower cardiovascular risk, is bringing endocrinologists and cardiologists together in a shared clinical experience. Discusses the intersection between metabolic disorders and cardiovascular diseases Provides a comprehensive understanding of the relevant pathophysiology of diseases as a basis for the evidence-based management of cardiometabolic disorders Offers a comprehensive reference, ranging from basic science and pathophysiology to clinical diagnostics and management