Cartilage And Osteoarthritis

Author : J.-Y. Reginster,J.-P. Pelletier,J. Martel-Pelletier,Y. Henrotin
Publisher : Springer Science & Business Media
Page : 509 pages
File Size : 50,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642600265

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Osteoarthritis by J.-Y. Reginster,J.-P. Pelletier,J. Martel-Pelletier,Y. Henrotin Pdf

Musculoskeletal diseases are rapidly becoming a major health concern. The incidence of osteoarthritis, the most common arthritic disorder, is increasing steadily due to the graying of the world population. This disease is responsible of human life, a time in for significant morbidity, particularly in the second half which the quality of life is of primary importance. The aim of this publication is to bring to physicians and scientists a comprehensive overview of the field, from molecules to men. The direct costs related to osteoarthritis have been increasing steadily over the years and will soon be comparable to those of other major illnesses, such as cardiovascular diseases. This, of course, does not take into account all of the other costs related to the disease which often cannot be simply calculated in dollars and cents. There has been a great deal of renewed interest in osteoarthritis in the last few decades. This has been brought on by the need to improve our knowledge of all aspects of the disease, especially with regard to its etiopathogenesis and treatment. The most recent findings and developments on the structural, bio chemical, biomechanical and molecular changes observed in clinical and ex perimental osteoarthritis are presented in this book.

Author : Felix Bronner,Mary C. Farach-Carson
Publisher : Springer Science & Business Media
Page : 220 pages
File Size : 46,6 Mb
Release : 2007-09-26
Category : Medical
ISBN : 9781846287015

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Bone and Osteoarthritis by Felix Bronner,Mary C. Farach-Carson Pdf

The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on genetics and on newer viewpoints and approaches, exemplified by the possible effect of subchondral bone on osteoarthritis, gives a wider viewpoint to the reader and may enable novel approaches to solving a clinical problem.

Author : Klaus E. Kuettner
Publisher : Lippincott Williams & Wilkins
Page : 808 pages
File Size : 49,9 Mb
Release : 1992
Category : Health & Fitness
ISBN : UOM:39015025161202

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Articular Cartilage and Osteoarthritis by Klaus E. Kuettner Pdf

Author : Nigel Arden,Francisco Blanco,C. Cooper,Ali Guermazi,Daichi Hayashi,David Hunter,M. Kassim Javaid,Francois Rannou,Frank Roemer,Jean-Yves Reginster
Publisher : Springer
Page : 99 pages
File Size : 46,9 Mb
Release : 2015-01-19
Category : Medical
ISBN : 9781910315163

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Atlas of Osteoarthritis by Nigel Arden,Francisco Blanco,C. Cooper,Ali Guermazi,Daichi Hayashi,David Hunter,M. Kassim Javaid,Francois Rannou,Frank Roemer,Jean-Yves Reginster Pdf

This Atlas provides an up-to-date and comprehensive overview of the historical and current perspectives on osteoarthritis, including the pathophysiology and epidemiology of the disease. Written by leading authors in the field of osteoarthritis, the book discusses classification, etiology and risk factors for osteoarthritis, the disease course and determinants of osteoarthritis progression, clinical features and diagnosis as well as imaging methods to assess joint damage. The Atlas of Osteoarthritis concludes with the latest treatment updates including both nonpharmacological and pharmacological treatments, as well as surgical recommendations for patients with the disease. Osteoarthritis is the most common form of joint disease causing joint pain, stiffness, and physical disability among adults. It is an important issue for both the individual and society with its impact on public health continuing to grow as a result of the aging population, the rising prevalence of obesity, and the lack of definitive treatments to prevent or halt the progress of the disease.

Author : Bruce M. Rothschild
Publisher : BoD – Books on Demand
Page : 606 pages
File Size : 43,6 Mb
Release : 2012-02-22
Category : Medical
ISBN : 9789535100638

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Principles of Osteoarthritis by Bruce M. Rothschild Pdf

This volume addresses the nature of the most common form of arthritis in humans. If osteoarthritis is inevitable (only premature death prevents all of us from being afflicted), it seems essential to facilitate its recognition, prevention, options, and indications for treatment. Progress in understanding this disease has occurred with recognition that it is not simply a degenerative joint disease. Causative factors, such as joint malalignment, ligamentous abnormalities, overuse, and biomechanical and metabolic factors have been recognized as amenable to intervention; genetic factors, less so; with metabolic diseases, intermediate. Its diagnosis is based on recognition of overgrowth of bone at joint margins. This contrasts with overgrowth of bone at vertebral margins, which is not a symptomatic phenomenon and has been renamed spondylosis deformans. Osteoarthritis describes an abnormality of joints, but the severity does not necessarily produce pain. The patient and his/her symptoms need to be treated, not the x-ray.

Author : Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi
Publisher : CRC Press
Page : 442 pages
File Size : 49,6 Mb
Release : 2017-01-06
Category : Medical
ISBN : 9781351722322

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Articular Cartilage by Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi Pdf

Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.

Author : Joseph A. Buckwalter,Martin K. Lotz,J. F. Stoltz
Publisher : IOS Press
Page : 316 pages
File Size : 55,6 Mb
Release : 2007
Category : Health & Fitness
ISBN : 9781586037734

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Osteoarthritis, Inflammation and Degradation by Joseph A. Buckwalter,Martin K. Lotz,J. F. Stoltz Pdf

Osteoarthritis is a public health issue due to its impact in term of handicap. Regarded as a multi-factorial disease, mechanistic and inflammatory theories are no more opposed but, on the contrary, are framed within the same continuum: osteoarthritis, inflammation and degeneration. This book helps readers understand the secrets of this disease.

Author : Massimo Sabatini,Philippe Pastoureau,FrTdTric De Ceuninck
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 42,9 Mb
Release : 2008-02-01
Category : Medical
ISBN : 9781592598106

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Cartilage and Osteoarthritis by Massimo Sabatini,Philippe Pastoureau,FrTdTric De Ceuninck Pdf

Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover.

Author : Roland W. Moskowitz
Publisher : Lippincott Williams & Wilkins
Page : 492 pages
File Size : 48,5 Mb
Release : 2007
Category : Medical
ISBN : 0781767075

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Osteoarthritis by Roland W. Moskowitz Pdf

Written by the foremost experts, this text is a comprehensive clinical reference on osteoarthritis. Chapters review current information on the epidemiology, etiopathogenesis, and pathology of osteoarthritis, the biochemistry and molecular and cell biology of articular cartilage, and experimental models of osteoarthritis. Major sections focus on clinical presentations, roentgenologic and laboratory diagnosis, and treatment, including pharmacologic treatment, intra-articular therapy, surgery, arthroscopy, and complementary and alternative medicine. The authors discuss the indications, outcomes, and complications of various orthopaedic procedures. Chapters present orthopaedic approaches to osteoarthritis of various joints—the shoulder, hand, wrist, elbow, hip, knee, foot, ankle, and cervical, thoracic, and lumbar spine.

Author : Qian Chen
Publisher : BoD – Books on Demand
Page : 276 pages
File Size : 46,7 Mb
Release : 2015-07-01
Category : Medical
ISBN : 9789535121367

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Osteoarthritis by Qian Chen Pdf

The most common form of arthritis is osteoarthritis (OA), which most often affects the hip, knee, foot and hand. The degeneration of joint cartilage and changes in underlying bone and supporting tissues such as ligament leads to pain, stiffness, movement problems and activity limitations. This book, containing three major sections in OA research and therapy, is an update of the book Osteoarthritis - Diagnosis, Treatment and Surgery published by InTech in 2012. The authors are experts in the osteoarthritis field, which include biologists, bioengineers, clinicians, and health professionals. The scientific content of the book will be beneficial to patients, students, researchers, educators, physicians, and health care providers who are interested in the recent progress in osteoarthritis research and therapy.

Author : Francisco Airton Castro Rocha,João Eurico Fonseca,Ali Mobasheri,Oreste Gualillo,Henrotin Edgard Henrotin,Raquel Largo,Gabriel Herrero-Beaumont
Publisher : Frontiers Media SA
Page : 124 pages
File Size : 50,8 Mb
Release : 2021-09-23
Category : Medical
ISBN : 9782889713387

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Inflammation and Biomarkers in Osteoarthritis by Francisco Airton Castro Rocha,João Eurico Fonseca,Ali Mobasheri,Oreste Gualillo,Henrotin Edgard Henrotin,Raquel Largo,Gabriel Herrero-Beaumont Pdf

Author : Hashmi Syed Musab Rahim, Fatima Lubna
Publisher : JAYPEE BROTHERS PUBLISHERS
Page : 208 pages
File Size : 49,8 Mb
Release : 2024-06-29
Category : Electronic
ISBN : 9789350900451

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Step by Step® Treatment of Osteoarthritis Knee by Hashmi Syed Musab Rahim, Fatima Lubna Pdf

Author : Frédéric De Ceuninck,Massimo Sabatini,Philippe Pastoureau
Publisher : Humana Press
Page : 346 pages
File Size : 50,5 Mb
Release : 2004-08-04
Category : Medical
ISBN : 1588295052

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Cartilage and Osteoarthritis by Frédéric De Ceuninck,Massimo Sabatini,Philippe Pastoureau Pdf

An indispensable collection of updated classical and emerging techniques that promise to add critical knowledge to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for the study-at the tissue level-of turnover, structure, and functioning of normal and diseased articular cartilage by invasive and noninvasive means. Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists with readily reproducible protocols for new experiments to understand-from the cellular to the animal level-the pathophysiology of cartilage and to discover molecular targets for pharmacological intervention.

Author : Kyriacos Athanasiou,Eric M. Darling,Jerry C. Hu
Publisher : Springer Nature
Page : 174 pages
File Size : 47,7 Mb
Release : 2022-06-01
Category : Science
ISBN : 9783031025785

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Articular Cartilage Tissue Engineering by Kyriacos Athanasiou,Eric M. Darling,Jerry C. Hu Pdf

Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions

Author : Gene G Hunder
Publisher : Orient Paperbacks
Page : 204 pages
File Size : 55,9 Mb
Release : 2006-10
Category : Family & Relationships
ISBN : 8122202837

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Mayo Clinic On Arthritis by Gene G Hunder Pdf

Arthritis pain can be frustrating. And so can sorting through the various available pain relief alternatives. Mayo Clinic is dedicated to helping you live more productively and comfortably with arthritis. The book focuses on osteoarthritis and rheumatoid arthritis, but is equally valuable to people with other forms of arthritis as well. The book relies on the experience of Mayo Clinic physicians, nurses, research scientists, therapists, and other health care professionals, the ultimate aim of which is to promote self-help. This easy to read and understand book offers advice on understanding arthritis, protecting joints, exercising properly, controlling pain, healthful diet and nutrition, traveling with arthritis, and working with arthritis. The nexus between the mind and the body and the impact of emotions, stress, and relaxation is also explored in Mayo Clinic On Arthritis. The gamut of treatments existing for arthritis including medications, surgery, and alternative approaches is listed together with information on the newest treatments trends.