Circular Dichroism And Linear Dichroism

Author : Alison Rodger,Bengt Nordén
Publisher : Oxford University Press, USA
Page : 170 pages
File Size : 51,7 Mb
Release : 1997
Category : Science
ISBN : 019855897X

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Circular Dichroism and Linear Dichroism by Alison Rodger,Bengt Nordén Pdf

This book provides an introduction to all those who wish to use the complementary spectroscopic techniques of optical activity (circular dichroism, CD) and optical anisotropy (linear dichroism, LD) for the study of the structure of molecules and interactions between molecules in solution. It emphasizes these techniques and how to use them for both low and high molecular weight molecules. The book begins by describing the principles behind CD and LD and how these techniques can be used in the laboratory without using advanced maths or quantum mechanics. The next chapters describe how both techniques may be applied to the study of biological macromolecules and give a detailed description of how they may be used on small molecules to investigate molecular and electronic structure. The final part contains theoretical derivations of all the equations required for the applications described previously. Specific molecular examples are used to illustrate concepts and to show the reader how to use the techniques in chemical and biological systems. Circular Dichroism and Linear Dichroism is an easy guide to what a prospective user of CD needs to know and explains how LD is not merely an exotic technique only to be practiced by experienced spectroscopists, but may be routinely and usefully employed as an aid to molecular structure determination.

Author : Bengt Nordén,Alison Rodger,Tim Dafforn
Publisher : Royal Society of Chemistry
Page : 305 pages
File Size : 51,7 Mb
Release : 2019-05-02
Category : Science
ISBN : 9781788018210

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Linear Dichroism and Circular Dichroism by Bengt Nordén,Alison Rodger,Tim Dafforn Pdf

This book provides an introduction to optical anisotropy (linear dichroism, LD) and optical activity (circular dichroism, CD) as techniques for the study of structures and interactions of molecules in solution. The book covers the use of these techniques for both small and large molecular systems with particular emphasis being placed on proteins and nucleic acids. CD is a well-established technique and this book aims to explain how it can be used simply and effectively for new entrants to the field as well as covering more advanced techniques for experts. LD is often seen as a rather exotic method intended only for experienced spectroscopists. This book demonstrates that it is an approach with real utility that may be used by both students and scientists from graduate level onwards to give simple answers, which are not available from any other technique, to structural and kinetic questions. Much of the emphasis is on flow orientation of samples in solution phase. The book first describes the techniques and the information they can provide; it then goes on to give specific details on how to actually implement them, including a wide range of examples showing how LD and CD can help with * protein and nucleic acid secondary structure elucidation; * analysis of the formation and rearrangements of fibrous proteins and membrane proteins; * identification of the absolute configuration of small molecules; * determination of the orientation of small molecules in anisotropic media; * assignment of transition moment polarizations; * investigation of binding strengths and geometries of ligand-macromolecule complexes; * 3-D structure determination from LD, molecular replacement and MD modeling. The advantages of combined LD/CD studies are also outlined with examples of DNA/drug complexes and protein insertion into membranes. Taken together the book represents a comprehensive text on the theory and application of LD and CD in the chemical and biological sciences.

Author : Bonnie Ann Wallace,Robert William Janes
Publisher : IOS Press
Page : 244 pages
File Size : 52,6 Mb
Release : 2009
Category : Medical
ISBN : 9781607500001

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Modern Techniques for Circular Dichroism and Synchrotron Radiation Circular Dichroism Spectroscopy by Bonnie Ann Wallace,Robert William Janes Pdf

Presents an account of circular dichroism (CD) spectroscopy and its application to structural biology. This book covers the methods of synchrotron radiation circular dichroism (SRCD) and linear dichroism (LD).

Author : Jasmin Wallace
Publisher : Unknown
Page : 195 pages
File Size : 48,8 Mb
Release : 2015
Category : SCIENCE
ISBN : 1634838009

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Circular and Linear Dichroism by Jasmin Wallace Pdf

This book provides readers with the latest developments in circular and linear dichroism research. Topics covered include the visible circular and linear magnetic dichroism in manganite thin films; the optical and energetic contributions of DNA secondary motifs to the trombin aptamer quadruplex and a review of the current theoretical understanding of the x-ray magnetic circular and linear dichroism (XMCD, XLD) of diluted magnetic semiconductors (DMS).

Author : Bengt Nordén
Publisher : Lund University Press
Page : 278 pages
File Size : 46,7 Mb
Release : 1977
Category : Science
ISBN : CORNELL:31924004749788

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Linear Dichroism Spectroscopy by Bengt Nordén Pdf

Author : B. Samori',E.W. Thulstrup
Publisher : Springer Science & Business Media
Page : 576 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400930391

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Polarized Spectroscopy of Ordered Systems by B. Samori',E.W. Thulstrup Pdf

Ordered systems exhibit physical properties and behavior unknown in media where structural ordering and organization do not take place. In ordered systems special correlations between molecules exist and the results are remarkable properties: the functional order of biological systems, the electrooptical and mechanical proper ties of liquid crystalline materials and stretched polymers are just a few examples. New methods and techniques in optical spectroscopy have recently been developed to study ordered systems and guest molecules. This stimulated the organization of a NATO Advanced Study Institute bringing together chemists and physicists from optical spectroscopy, materials science, and biology. Thereby a unifying and interdisciplinary survey of possible applications of spectroscopy with polarized light to ordered systems, such as liquid crystals, stretched polymers, polymeric liquid crystals, and membranes, was achieved. The interdisciplinary approach of the meeting is reflected in the book. Different aspects of the same topic are often treated in several chapters all through the book. Therefore, each reader should look for the contributions which serves his needs, even if this means that some chapters will be skipped. The Advanced Study Institute, "New Developments in Polarized Spectroscopy of Ordered Systems", was the first scientific event of the celebrations of the 900th anniversary of the University of Bologna. The international and multidisciplinary approach of this ASI well converged in the tradition of the "Studium" at Bologna.

Author : W. Roy Mason
Publisher : John Wiley & Sons
Page : 237 pages
File Size : 51,5 Mb
Release : 2007-07-09
Category : Science
ISBN : 9780470139226

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Magnetic Circular Dichroism Spectroscopy by W. Roy Mason Pdf

The book is a technical guide for chemists and spectroscopists, and presents a concise description of magnetic circular dichroism (MCD) spectroscopy and how it has advanced the interpretation of molecular electronic spectra. Provides a practical guide to utilizing MCD spectroscopy for chemists starting in the field Written by an expert with over twenty years of experience in the field Helps the reader to visualize the optical spectroscopic effects presented by MCD measurements Includes practical considerations for experimental MCD measurements based on the author's experience Written as a general discussion of the subject matter, with illustrative examples provided and discussed in the case studies to show the breadth of application of MCD measurements.

Author : Nina Berova,Koji Nakanishi,Robert W. Woody
Publisher : John Wiley & Sons
Page : 916 pages
File Size : 44,5 Mb
Release : 2000-05-03
Category : Science
ISBN : 0471330035

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Circular Dichroism by Nina Berova,Koji Nakanishi,Robert W. Woody Pdf

Unter Zirkulardichroismus (CD) versteht man die spezifisch unterschiedliche Absorption von links- und rechtszirkular polarisiertem Licht durch bestimmte Moleküle. CD-Effekte lassen sich in Abhängigkeit von der Wellenlänge messen und spektroskopisch auswerten. Dieser Band erläutert Theorie und Anwendung der CD-Spektroskopie insbesondere für Biomoleküle. Ausführlich behandelt werden Anwendungen auf den Gebieten der organischen Stereochemie und der Biopolymere. Geschrieben von anerkannten Spezialisten! (06/00)

Author : G.D. Fasman
Publisher : Springer Science & Business Media
Page : 739 pages
File Size : 45,8 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781475725087

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Circular Dichroism and the Conformational Analysis of Biomolecules by G.D. Fasman Pdf

''Excellent and very timely....It will undoubtedly become a standard reference for the application of circular dichroism (CD) to biomolecules.'' --- Quarterly Review of Biology, March 1997 ''[T]estament to the book's utility is the fact that during the course of my review I had to 'rescue' it from the desks of graduate students on an almost daily basis. In summary, this is a great book.'' --- American Scientist ''Well documented chapters provide a very good insight into the problems surrounding the conformation of biomacromolecules...An indispensible source of information.'' --- Nahrung, 42(2), 1998 Renowned experts present the first state-of-the-art description of circular dichroism spectroscopy (CD). Chapters present in-depth discussions of the history of the field, the theory of CD for application to globular proteins, membrane proteins, peptides, nucleic acids and their interactions, carbohydrates, and instrumentation. Discussions also feature new techniques using synchrotron radiation, vibrational Raman optical activity, and vibrational CD. More than 250 illustrations supplement the text.

Author : Michael Wirth
Publisher : Unknown
Page : 51 pages
File Size : 47,7 Mb
Release : 1986
Category : Circular dichroism
ISBN : 9170322538

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Electric Orientation Relaxation, Flow Linear Dichroism and Circular Dichroism Applied to DNA Complexes with Intercalators and Potentially Multi-intercalating Ligands by Michael Wirth Pdf

Author : N. Purdie,H.G. Brittain
Publisher : Elsevier
Page : 347 pages
File Size : 43,8 Mb
Release : 1993-12-01
Category : Science
ISBN : 0080875629

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Analytical Applications of Circular Dichroism by N. Purdie,H.G. Brittain Pdf

Circular dichroism is a special technique which provides unique information on dissymmetric molecules. Such compounds are becoming increasingly important in a wide variety of fields, such as natural products chemistry, pharmaceutics, molecular biology, etc. The content of this book has been selected in order to feature the unique aspects of circular dichroism, and how these strengths can be of assistance to workers in the field. Substantial discussions have been provided regarding the particular phenomena associated with dissymmetric compounds which give rise to the circular dichroism effect. Reviews are also given of the type of instrumentation available for the measurement of these effects. A number of chapters cover the wide range of applications illustrating the power of the method. Owing to its broad appeal, the book will be of interest to workers in all areas of chemistry and pharmaceutical science.

Author : Nagao Kobayashi,Atsuya Muranaka
Publisher : Royal Society of Chemistry
Page : 216 pages
File Size : 46,6 Mb
Release : 2011-11-10
Category : Science
ISBN : 9781849732932

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Circular Dichroism and Magnetic Circular Dichroism Spectroscopy for Organic Chemists by Nagao Kobayashi,Atsuya Muranaka Pdf

CD and MCD spectroscopy can provide key information about the conformations and electronic states of chromophore containing molecules. However, the theory has remained too challenging and inaccessible for many organic chemists and biochemists and only a few researchers have carried out detailed quantitative analyses of their spectral data. This is not surprising as people who excel at spectroscopic theory usually lack the skills set required to design and synthesise the molecules that would be most appropriate for describing and explaining the theory of CD and MCD spectroscopy. Most of the books that have been written on the subject have, therefore, been based on very dense sets of mathematical equations. This timely book rectifies that situation by summarizing the relationship between the different types of spectra and by describing in detail the qualitative and quantitative methods which can readily be used to analyse CD and MCD spectral data. During the last decade the authors have successfully synthesized several molecules to illustrate key points related to the theory of CD and MCD spectroscopy, resulting in this definitive book providing key practical knowledge in a readily accessible style. It is aimed primarily at organic chemists and biochemists and is required reading for researchers active in the field. In the introduction, the book describes the types of information that can be derived from CD and MCD spectroscopy. After a detailed explanation of the theory of electronic absorption spectroscopy, it then provides practical in depth examples of the various analytical methods that can be carried out with CD and MCD spectral data. This makes the theory of these techniques much more accessible for researchers who do not specialise in physical chemistry. The book concludes by briefly summarizing the key mathematical expressions associated with each technique.

Author : Hisako Sato
Publisher : Springer Nature
Page : 213 pages
File Size : 44,7 Mb
Release : 2024-06-27
Category : Electronic
ISBN : 9789819703913

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Multi-dimensional Vibrational Circular Dichroism by Hisako Sato Pdf

Author : E.W. Thulstrup
Publisher : Springer Science & Business Media
Page : 110 pages
File Size : 51,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642931369

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Aspects of the Linear and Magnetic Circular Dichroism of Planar Organic Molecules by E.W. Thulstrup Pdf

Author : Hans J. Vogel
Publisher : Springer Science & Business Media
Page : 346 pages
File Size : 50,7 Mb
Release : 2008-02-04
Category : Science
ISBN : 9781592591831

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Calcium-Binding Protein Protocols by Hans J. Vogel Pdf

Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so it modifies their biological activity or their stability. Because of its distinct che- cal properties calcium is uniquely suited to act as an on–off switch or as a light dimmer of biological activities. The two books entitled Calcium-Binding Protein Protocols (Volumes I and II) focus on modern experimental analyses and methodologies for the study of calcium-binding proteins. Both extracel- lar and intracellular calcium-binding proteins are discussed in detail. H- ever, proteins involved in calcium handling (e. g. , calcium pumps and calcium channels), fall outside of the scope of these two volumes. Also, calcium-bi- ing proteins involved in bone deposition will not be discussed, as this specific topic has been addressed previously. The focus of these two books is on studies of the calcium-binding proteins and their behavior in vitro and in vivo. The primary emphasis is on protein chemistry and biophysical methods. Many of the methods described will also be applicable to proteins that do not bind calcium. Calcium-Binding Protein Protocols is divided into three main sections. The section entitled Introduction and Reviews provides information on the role of calcium in intracellular secondary messenger activation mechanisms. Mo- over, unique aspects of calcium chemistry and the utilization of calcium in dairy proteins, as well as calcium-binding proteins involved in blood clotting, are addressed.