Controversial Issues In The Management Of Head And Neck Cancer A Swiss Multidisciplinary And Multi Institutional Patterns Of Care Study

Author : Olgun Elicin,Marco Siano,Christian Simon
Publisher : Frontiers Media SA
Page : 37 pages
File Size : 50,5 Mb
Release : 2020-02-26
Category : Electronic
ISBN : 9782889635443

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Controversial Issues in the Management of Head and Neck Cancer: A Swiss Multidisciplinary and Multi-Institutional Patterns of Care Study by Olgun Elicin,Marco Siano,Christian Simon Pdf

The heterogeneity in the practice of diagnosis and treatment of head and neck squamous cell carcinoma (HNSCC) is known and expected to be inversely correlated with the level of evidence on a given topic. Literature on various aspects of management of HNSCC were previously published, but were usually restricted within narrow foci. Due to the lack of a similar comprehensive work published so far, the Head and Neck Cancer Working Group of Swiss Group for Clinical Cancer Research (SAKK) decided to perform a survey covering the whole spectrum of controversial topics concerning the diagnosis and the treatment of HNSCC among its member institutions. This survey was designed to discuss current diagnostic and treatment strategies for HNSCC of all localizations, and to find out probable differences and level of consensus between the participating academic institutions by means of a questionnaire-based pattern of care study. The items in the survey was generated with a scored voting system by inclusion of all involved centers, and divided into four sections, each of them not exceeding twenty questions: head and neck surgery, radiation oncology, medical oncology and biomarkers. Surely, the topics and questions were intentionally chosen from controversial areas. Nonetheless, the lack of major consensus in most queried areas provide an insight to head and neck oncologist in terms of the scope of heterogeneity in their practice. Although none of the participated centers being plainly wrong, it is still disturbing to see, that a patient may be treated with quite discrepant diagnostic and treatment concepts even in a relatively small country adhering to up to date evidence based medicine. We believe that this work will serve the head and neck oncologists to be aware of their discrepancies and to stimulate discussion toward standardization of practice and prioritize topics of future clinical research.

Author : Ho-Hyun (Brian) Sun
Publisher : BoD – Books on Demand
Page : 192 pages
File Size : 48,6 Mb
Release : 2021-10-13
Category : Medical
ISBN : 9781838819835

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Surgical Management of Head and Neck Pathologies by Ho-Hyun (Brian) Sun Pdf

The book is an introduction to concepts in head and neck surgical pathology that are both novel and proven. Chapters discuss the various anatomic, reconstructive, and esthetic considerations that are often unique to surgeries of the head, face, and neck. International cooperation was made to ensure that a wide range of perspectives is presented in this volume.

Author : Sudhir Bahadur,Alok Thakar,Bidhu K. Mohanti
Publisher : Springer
Page : 226 pages
File Size : 41,9 Mb
Release : 2019-02-20
Category : Medical
ISBN : 9789811331107

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Carcinoma of the Larynx and Hypopharynx by Sudhir Bahadur,Alok Thakar,Bidhu K. Mohanti Pdf

Carcinomas of the larynx and hypopharynx present unique challenges when it comes to their assessment and management. Management involves the essential dilemma of optimizing cure rates while also ensuring that potential disability due to compromised airway, voice and swallowing is minimized. Treatment decisions involve careful disease assessment, judicious multispecialty decision-making, and subsequent meticulous implementation of the selected treatment modalities. The critical nature of each of these steps has led to dramatic advances in assessment techniques (radiology, endoscopy and photography, stroboscopy, narrow band imaging, contact endoscopy) and also in treatment methods (radiation therapy, combined concurrent chemo-radiation, combined sequential chemo-radiation, trans-oral CO2 laser and robotic surgery, partial laryngectomy, total laryngectomy, extended total laryngectomy). As such, treatment decisions have become increasingly complex with the twin objectives of maximizing cure as well as function preservation and are based on tumor stage, tumor location, systemic co-morbidities, nutritional status, patient priorities, and social and economic factors. This multidisciplinary book has been written by a team of editors with considerable experience and expertise in these critical areas and a deep understanding of teamwork and the strengths and limitations of individual technologies and treatments. It presents a homogeneous and unbiased view that is applicable to all specialties involved in the care of larynx and hypopharynx cancers.

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,International Agency for Research on Cancer
Publisher : IARC
Page : 354 pages
File Size : 54,9 Mb
Release : 2004
Category : Health & Fitness
ISBN : 9283212851

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Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,International Agency for Research on Cancer Pdf

A working group of sixteen experts from seven countries re-evaluated the evidence of the carcinogenicity of betel-quid and areca-nut chewing and some areca-nut related nitrosamines. Betel-quid and areca-nut chewing are widely practised in many parts of Asia and in Asian-migrant communities elsewhere in the world. There are hundreds of millions of users worldwide. They evaluated betel quid with tobacco as carcinogenic to humans (Group 1) on the basis of sufficient evidence of an increased risk of cancer of the oral cavity, pharynx and oesophagus. The working group reviewed epidemiological studies of human cancer, mainly studies from India, Pakistan and Taiwan (China). Studies on betel quid with tobacco and areca nut with tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. The working group also evaluated betel quid without tobacco as carcinogenic to humans (Group 1), on the basis of sufficient evidence of an increased risk of oral cancer. Studies on betel quid without tobacco and areca nut without tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. Areca nut, a common ingredient of betel quid and many different chewing preparations, including those available commercially, has been observed to cause oral submucous fibrosis

Author : N. J. Roland,Vinidh Paleri,British Association of Otolaryngologists
Publisher : Unknown
Page : 354 pages
File Size : 42,5 Mb
Release : 2011
Category : Head
ISBN : 0957013809

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Head and Neck Cancer by N. J. Roland,Vinidh Paleri,British Association of Otolaryngologists Pdf

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Publisher : National Academies Press
Page : 483 pages
File Size : 49,9 Mb
Release : 2017-09-28
Category : Medical
ISBN : 9780309459570

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Pain Management and the Opioid Epidemic by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse Pdf

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Author : International Atomic Energy Agency,Eduardo Zubizarreta
Publisher : Unknown
Page : 544 pages
File Size : 44,9 Mb
Release : 2017-11-28
Category : Medical
ISBN : 920115013X

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Radiotherapy in Cancer Care by International Atomic Energy Agency,Eduardo Zubizarreta Pdf

Cancer treatment is complex and calls for a diverse set of services. Radiation therapy is recognized as an essential tool in the cure and palliation of cancer. Currently, access to radiation treatment is limited in many countries and non-existent in some. This lack of radiation therapy resources exacerbates the burden of disease and underscores the continuing health care disparity among States. Closing this gap represents an essential measure in addressing this global health equity problem. This publication presents a comprehensive overview of the major topics and issues to be taken into consideration when planning a strategy to address this problem, in particular in low and middle income countries. With contributions from leaders in the field, it provides an introduction to the achievements and issues of radiation therapy as a cancer treatment modality around the world. Dedicated chapters focus on the new radiotherapy technologies, proton beams, carbon ion, intraoperative radiotherapy, radiotherapy for children, treatment of HIV-AIDS malignancies, and costing and quality management issues.

Author : P. Nicolai,P.J. Bradley
Publisher : Karger Medical and Scientific Publishers
Page : 266 pages
File Size : 40,5 Mb
Release : 2020-07-30
Category : Medical
ISBN : 9783318066708

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Anterior Skull Base Tumors by P. Nicolai,P.J. Bradley Pdf

In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.

Author : Alexander Birbrair
Publisher : Springer
Page : 208 pages
File Size : 43,7 Mb
Release : 2021-06-27
Category : Medical
ISBN : 3030445208

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Tumor Microenvironment by Alexander Birbrair Pdf

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research in the field. A variety of topics are covered, including metabolism in the tumor microenvironment, stellate cells and endothelial progenitors in the tumor microenvironment, as well as the effects of HIV, viral hepatitis, and inflammation in the tumor microenvironment, and more. Taken alongside its companion volumes, Tumor Microenvironment: State of the Science updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Author : Jochen A. Werner,R. Kim Davis
Publisher : Springer Science & Business Media
Page : 262 pages
File Size : 47,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642187223

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Metastases in Head and Neck Cancer by Jochen A. Werner,R. Kim Davis Pdf

-Richly illustrated; 109 illustrations, 57 in color -Cover a wide range of diagnostic and theraputic techniques, i.e. MRI, PET, surgical treatment, radiation therapy

Author : National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability
Publisher : Unknown
Page : 128 pages
File Size : 42,6 Mb
Release : 2021-09-09
Category : Electronic
ISBN : 0309683491

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Childhood Cancer and Functional Impacts Across the Care Continuum by National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability Pdf

Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Author : Edwin Choy
Publisher : MDPI
Page : 157 pages
File Size : 54,8 Mb
Release : 2018-10-08
Category : Connective tissues
ISBN : 9783906980461

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Soft Tissue and Bone Sarcoma by Edwin Choy Pdf

This book is a printed edition of the Special Issue "Soft Tissue and Bone Sarcoma" that was published in Cancers

Author : Louis B. Harrison,Roy B. Sessions,Waun Ki Hong
Publisher : Lippincott Williams & Wilkins
Page : 1004 pages
File Size : 42,9 Mb
Release : 2009
Category : Medical
ISBN : 0781771366

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Head and Neck Cancer by Louis B. Harrison,Roy B. Sessions,Waun Ki Hong Pdf

This comprehensive, multidisciplinary text addresses all aspects of head and neck cancer and represents a wide spectrum of specialists, including surgical, radiation, and medical oncologists, dentists, pathologists, radiologists, and nurses. The book focuses on a two-part approach to treatment that maximizes the chance for a cure while maintaining a strong emphasis on quality of life. This Third Edition's updated techniques section includes new radiation techniques such as IMRT and IGRT and new endoscopic and laser surgical techniques. Other highlights include a new chapter on reconstructive techniques; significant updates to all site-specific chapters; updates on chemoprevention and molecular targeting; and discussions of new imaging modalities such as fused PET/CT. A companion Website will offer the fully searchable text with all images.

Author : Saman Warnakulasuriya,John S. Greenspan
Publisher : Springer Nature
Page : 449 pages
File Size : 55,8 Mb
Release : 2020-02-22
Category : Medical
ISBN : 9783030323165

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Textbook of Oral Cancer by Saman Warnakulasuriya,John S. Greenspan Pdf

This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.

Author : Luis Requena,Omar Sangüeza
Publisher : Springer
Page : 1052 pages
File Size : 44,8 Mb
Release : 2017-12-28
Category : Medical
ISBN : 9783319457048

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Cutaneous Adnexal Neoplasms by Luis Requena,Omar Sangüeza Pdf

This superbly illustrated book is the most comprehensive available guide to adnexal neoplasms of the skin. More than 70 entities are described in individual chapters that follow a uniform structure: historical review, clinical features, histopathology, histogenesis, immunohistochemistry, molecular anomalies, and treatment. Readers will find state of the art knowledge on all aspects, including the cytogenetic and chromosomal abnormalities associated with each neoplasm. Without exception, the illustrations are high-quality, full-color, original digital pictures. The histopathology images are taken from perfectly cut and stained sections and the immunohistochemistry illustrations are of an unrivalled quality among textbooks of dermatology and dermatopathology. A complete list of references from original description to the present day is also supplied for each neoplasm. Cutaneous adnexal neoplasms are a large and heterogeneous group of benign and malignant lesions. This book will assist the reader in early and correct recognition, which is essential for appropriate choice of treatment and prognostic assessment.