Coulometric Electrode Array Detectors For Hplc

Author : Ian N. Acworth
Publisher : VSP
Page : 396 pages
File Size : 41,8 Mb
Release : 1997
Category : Science
ISBN : 9067642320

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Coulometric Electrode Array Detectors for Hplc by Ian N. Acworth Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.

Author : I.H. Acworth,M. Naoi,Hasan Parvez,S. Parvez
Publisher : CRC Press
Page : 393 pages
File Size : 48,5 Mb
Release : 2024-01-26
Category : Science
ISBN : 9781466563711

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Coulometric Electrode Array Detectors for HPLC by I.H. Acworth,M. Naoi,Hasan Parvez,S. Parvez Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.

Author : Robert J Flanagan,David Perrett,Robin Whelpton
Publisher : Royal Society of Chemistry
Page : 244 pages
File Size : 48,9 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847550729

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Electrochemical Detection in HPLC by Robert J Flanagan,David Perrett,Robin Whelpton Pdf

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Author : Alberto Escarpa,María Cristina González,Miguel Ángel López
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 52,7 Mb
Release : 2015-07-15
Category : Science
ISBN : 9781118682968

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Agricultural and Food Electroanalysis by Alberto Escarpa,María Cristina González,Miguel Ángel López Pdf

Agricultural and Food Electroanalysis offers a comprehensive rationale of electroanalysis, revealing its enormous potential in agricultural food analysis. A unique approach is used which fills a gap in the literature by bringing in applications to everyday problems. This timely text presents in-depth descriptions about different electrochemical techniques following their basic principles, instrumentation and main applications. Such techniques offer invaluable features such as inherent miniaturization, high sensitivity and selectivity, low cost, independence of sample turbidity, high compatibility with modern technologies such as microchips and biosensors, and the use of exciting nanomaterials such as nanoparticles, nanotubes and nanowires. Due to the advantages that modern electroanalytical techniques bring to food analysis, and the huge importance and emphasis given today to food quality and safety, this comprehensive work will be an essential read for professionals and researchers working in analytical laboratories and development departments, and a valuable guide for students studying for careers in food science, technology and chemistry.

Author : Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 46,9 Mb
Release : 2006-03-20
Category : Science
ISBN : 9780387252407

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Metabolome Analyses: by Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre Pdf

Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems.

Author : Leo M.L. Nollet
Publisher : CRC Press
Page : 1074 pages
File Size : 48,9 Mb
Release : 2000-04-05
Category : Technology & Engineering
ISBN : 082478460X

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Food Analysis by HPLC, Second Edition by Leo M.L. Nollet Pdf

Food Analysis by HPLC, Second Edition presents an exhaustive compilation of analytical methods that belong in the toolbox of every practicing food chemist. Topics covered include biosensors, BMO’s, nanoscale analysis systems, food authenticity, radionuclides concentration, meat factors and meat quality, particle size analysis, and scanning colorimity. It also analyzes peptides, carbohydrates, vitamins, and food additives and contains chapters on alcohols, phenolic compounds, pigments, and residues of growth promoters. Attuned to contemporary food industry concerns, this bestselling classic also features topical coverage of the quantification of genetically modified organisms in food.

Author : Kenneth Hensley,Robert A. Floyd
Publisher : Springer Science & Business Media
Page : 212 pages
File Size : 52,5 Mb
Release : 2008-02-06
Category : Medical
ISBN : 9781592594245

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Methods in Biological Oxidative Stress by Kenneth Hensley,Robert A. Floyd Pdf

Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few. Because of the centrality of oxidative processes to normal and abnormal tissue function, it has become imperative to develop appropriate analytical techniques to facilitate the quantitation of significant reactants. Without advances in methodology, corresponding advances in our knowledge of underlying biochemical events will be necessarily limited. Drs. Hensley and Floyd have done an outstanding job of assembling the work of world-class experts into Methods in Biological Oxidative Stress. The contributors have presented concise, yet thorough, descriptions of the state-of-the-art methods that any investigator working in the field needs to access. Mannfred A. Hollinger v Preface Free radicals and reactive oxidizing agents were once ignored as biochemical entities not worth close scrutiny, but are now recognized as causes or contributing factors in dozens, if not hundreds, of disease states. In addition, free radical metabolisms of xenobiotics have become increasingly important to pharmacologists. Accordingly, the need has arisen to accurately quantify reactive oxygen species and their byproducts. Methods in Biological Oxidative Stress is practical in scope, providing the details of up-to-date techniques for measuring oxidative stress and detecting oxidizing agents both in vitro and in vivo. The contributors are recognized experts in the field of oxidative stress who have developed novel strategies for studying biological oxidations.

Author : Donald Armstrong
Publisher : Springer Science & Business Media
Page : 320 pages
File Size : 46,5 Mb
Release : 2008-02-04
Category : Science
ISBN : 9781592591732

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Oxidative Stress Biomarkers and Antioxidant Protocols by Donald Armstrong Pdf

The first protocols book, Free Radical and Antioxidant Protocols (1) was published in late 1998. Sections were divided into three parts, covering selected biochemical techniques for measuring oxidative stress, antioxidant (AOX) activity, and combined applications. In choosing the 40 methods to be included in that book, I realized there were considerably more of equal value than that which we could have presented in a single volume. To produce a comprehensive resource, this book and a third are being compiled to expand coverage of the field. A summary of papers (2) published on this important subject emphasizes the continuing rapid growth in oxidative stress investigations relating to our understanding of biochemical reactions, their relevance to pathophysiological mechanisms, how disease may arise, and how therapeutic intervention may be achieved(3). Although there is some overlap between the categories, the ana- sis shown below illustrates where current studies are concentrated and are almost evenly distributed between free radicals and AOX. Over the last 4 yr, there has been a 55% increase in the number of papers published in the area.

Author : G. a. Qureshi
Publisher : VSP
Page : 880 pages
File Size : 48,6 Mb
Release : 1998-03
Category : Medical
ISBN : 9067642770

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Neurochemical Markers of Degenerative Nervous Diseases and Drug Addiction by G. a. Qureshi Pdf

Author : Patricia A. Broderick,David N. Rahni,Edwin H. Kolodny
Publisher : Springer Science & Business Media
Page : 313 pages
File Size : 51,6 Mb
Release : 2007-11-05
Category : Medical
ISBN : 9781592598885

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Bioimaging in Neurodegeneration by Patricia A. Broderick,David N. Rahni,Edwin H. Kolodny Pdf

Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK ® However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids.

Author : Zhimin Xu,Luke R. Howard
Publisher : John Wiley & Sons
Page : 405 pages
File Size : 40,8 Mb
Release : 2012-02-03
Category : Technology & Engineering
ISBN : 9781118229385

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Analysis of Antioxidant-Rich Phytochemicals by Zhimin Xu,Luke R. Howard Pdf

To quantify antioxidants in natural sources, the application of chromatography techniques with different detectors followed by skillful sample preparation is necessary. Analysis of Antioxidant-Rich Phytochemicals is the first book that specifically covers and summarizes the details of sample preparation procedures and methods developed to identify and quantify various types of natural antioxidants in foods. Focusing on the principle of quantification methods for natural antioxidants, the book reviews and summarizes current methods used in the determination of antioxidant-rich phytochemicals in different sources. Chapter by chapter, the distinguished team of authors describes the various methods used for analysis of the different antioxidant-rich phytochemicals – phenolic acids; carotenoids; anthocyanins; ellagitannins, flavonols and flavones; catechins and procyanidins; flavanones; stilbenes; phytosterols; and tocopherols and tocotrienols. Going beyond extensive reviews of the scientific literature, the expert contributors call on their accumulated experience in sample extraction and analysis to outline procedures, identify potential problems in dealing with different samples, and offer trouble-shooting tips for the analysis. Analysis of Antioxidant-Rich Phytochemicals covers the important food applications and health-promoting functions of the major antioxidant phytochemicals, presents general analysis principles and procedures, and systematically reviews and summarizes the various analytical methods necessary for each type of natural antioxidant in different food sources.

Author : Richard G. Cutler
Publisher : World Scientific
Page : 872 pages
File Size : 50,8 Mb
Release : 2003
Category : Family & Relationships
ISBN : 9789812775733

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Critical Reviews of Oxidative Stress and Aging by Richard G. Cutler Pdf

This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.

Author : Robert James Flanagan,David Perrett,Robin Whelpton
Publisher : Royal Society of Chemistry
Page : 258 pages
File Size : 55,9 Mb
Release : 2005
Category : Science
ISBN : 0854045325

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Electrochemical Detection in HPLC by Robert James Flanagan,David Perrett,Robin Whelpton Pdf

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Author : Lester Packer
Publisher : Gulf Professional Publishing
Page : 574 pages
File Size : 46,7 Mb
Release : 1999
Category : Active oxygen
ISBN : 012182201X

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Oxidants and Antioxidants by Lester Packer Pdf

General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Total Antioxidant Activity * Vitamin C * Polyphenols and Flavanoids * Thiols * Vitamin E and Coenzyme Q10 * Carotenoids and Retinoids.

Author : Craig Banks,Roger Mortimer,Steven McIntosh
Publisher : Royal Society of Chemistry
Page : 220 pages
File Size : 44,8 Mb
Release : 2015-11-19
Category : Electrochemistry
ISBN : 9781849739801

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Electrochemistry by Craig Banks,Roger Mortimer,Steven McIntosh Pdf

The Specialist Periodical Report Electrochemistry presents comprehensive and critical reviews in all aspects of the field, with contributions from across the globe, providing the reader with an informed digest of the most important research currently carried out in this field. Re-launching in 2015 with a new editorial team, Volume 13 returns to its roots and provides a wide range of topics written by leading experts researching at the forefront and heart of electrochemistry. The book covers topics such as control and structural analysis, and combines different approaches on utilizing light as a source for materials science. This volume is a key reference in the field of electrochemistry, allowing readers to become easily acquainted with the latest research trends.