Electrochemical Detection In Hplc

Author : Robert J Flanagan,David Perrett,Robin Whelpton
Publisher : Royal Society of Chemistry
Page : 244 pages
File Size : 45,5 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847550729

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Electrochemical Detection in HPLC by Robert J Flanagan,David Perrett,Robin Whelpton Pdf

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Author : Ian N. Acworth
Publisher : VSP
Page : 396 pages
File Size : 52,6 Mb
Release : 1997
Category : Science
ISBN : 9067642320

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Coulometric Electrode Array Detectors for Hplc by Ian N. Acworth Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.

Author : H. Parvez
Publisher : VSP
Page : 490 pages
File Size : 43,8 Mb
Release : 1987-12
Category : Science
ISBN : 906764062X

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Electrochemical Detection in Medicine And Chemistry by H. Parvez Pdf

Author : T. Ryan
Publisher : Springer Science & Business Media
Page : 171 pages
File Size : 43,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461593973

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Electrochemical Detectors by T. Ryan Pdf

The widely perceived utility of electrochemical detectors in High Performance Liquid Chromatography has focussed attention on a number of disparate aspects of electrochemistry related to their successful design and application. The papers in this volume deal with an extraordinarily wide range of topics but all have the common focus of electrochemical detection as a practical chromatographic tool. While it is certainly not essential to be familiar with the theoretical principles in order to utilize it successfully, the determined user of electrochemical detector will seek to have an understanding of the background. Some of the following pages will provide an excellent grounding as well as pointing the potential user in the direction of proven and possible applications in a variety of fields. The meeting, of which this book is a record, was the fifth event in the biannual Anglo-Czech Symposia in Electrochemistry. The organ izers of that meeting were extremely pleased to welcome a select group of scientists from the J Heyrovsky Institute of Physical Chemistry and Electrochemistry to the meeting, thus continuing a tradition of cooperation and friendship going back over ten years. The contributions of the visitors to the scientific content of the meeting were enthusiastically received and their participation in the informal and social activities can only have furthered the cause of cooperation and good will between our two countries.

Author : William R. LaCourse
Publisher : Wiley-Interscience
Page : 360 pages
File Size : 41,5 Mb
Release : 1997-08-18
Category : Science
ISBN : UOM:39015050267783

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Pulsed Electrochemical Detection in High-Performance Liquid Chromatography by William R. LaCourse Pdf

A reliable, comprehensive, relevant view of HPLC and its applications The development of HPLC-PED represents the successful marriage of two powerful analytical technologies and has resulted in the best technique for sensitive and direct detection of biological compounds with poor optical detection properties. PED has been used extensively for the determination of carbohydrates and other polar aliphatic compounds, and as a result, numerous methods have been developed to enable the analysis of a wide variety of samples. Over the years, many articles, anecdotal information, and misinformation have permeated the scientific community, with the possible consequence of confusion or uncertainty with regard to PED on the part of the analyst. Pulsed Electrochemical Detection in High-Performance Liquid Chromatography presents a reliable, comprehensive, and relevant review of HPLC-PED and its applications. The book is divided into three major parts: background material necessary for a more thorough understanding of the principles and relevance of PED; an in-depth discussion of PED using voltammetry and other electroanalytical techniques and presenting the advantages, applicability, and optimization of all existing PED waveforms; and practical aspects of HPLC-PED, including a summary of the major applications and a look at future developments in the technique. Appendices include a pulsed voltammetry (PV) program specifically written to optimize pulsed amperometric detection (PAD) waveforms and all the known applications, categorized and listed in tabular form. For analytical chemists; biochemists; carbohydrate chemists; biotechnologists; undergraduate, graduate, and postdoctoral students; and lab technicians working in a range of areas including the pharmaceutical, medical, and food and beverage industries, this eminently readable guide is the first reliable book-length treatment of how to use PED coupled with HPLC.

Author : Walter Lowry Candill
Publisher : Unknown
Page : 398 pages
File Size : 53,6 Mb
Release : 1983
Category : Electrochemical apparatus
ISBN : IND:39000000774252

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Development and Application of High Performance Liquid Chromatography with Electrochemical Detection by Walter Lowry Candill Pdf

Author : Donald Parriott
Publisher : Academic Press
Page : 293 pages
File Size : 46,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323140614

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A Practical Guide to HPLC Detection by Donald Parriott Pdf

This guide for the practicing chromatographer who wants a ready source of information on HPLC detection explores and compares existing detection systems and detectors, outlines the common problems associated with a given detector, and offers proven approaches to avoiding such problems. Addresses the practical aspects of HPLC detection, including: basic theory, when a particular type of detector can be used, how detectors from various manufacturers differ, common problems of detectors and ways to avoid them Presents an overview of today's most common techniques Discusses the advantages and disadvantages of HPLC, dispelling common misconceptions

Author : P. T. Kissinger
Publisher : Unknown
Page : 128 pages
File Size : 42,5 Mb
Release : 2024-05-22
Category : Electronic
ISBN : 0824700198

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Electrochemical Detection in HPLC and HPCE by P. T. Kissinger Pdf

Author : Anonim
Publisher : Elsevier
Page : 452 pages
File Size : 43,6 Mb
Release : 1987-12-01
Category : Science
ISBN : 0080858422

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Selective Sample Handling and Detection in High-Performance Liquid Chromatography by Anonim Pdf

This book is the first of a two-volume project which attempts to treat the sample handling and detection processes in a liquid chromatographic system in an integrated fashion. The need for more selective and sensitive chromatographic methods to help solve the numerous trace analysis problems in complex samples is undisputed. However, few workers realize the strong interdependence of the various steps - sample handling, separation and detection - which must be considered if one wants to arrive at an optimal solution. By introducing a strong element of selectivity and trace enrichment in the sample preparation step, fewer demands are placed on the quality of the chromatography and often a simple UV detector can be used. By using a selective detection mode, i.e. a reaction detector, the sample handling step can frequently be simplified and more easily automated. The impact of such a ``total system'' approach on handling series of highly complex samples such as environmental specimens or biological fluids can be easily imagined. Each chapter includes sufficient references to the literature to serve as a valuable starting point for more detailed investigation. Special emphasis is placed on the sample handling, and high priority has been given to the treatment of chemical principles applied to the topics presented, rather than to instrumentation. Written by experienced practitioners, this volume will be of interest to investigators in many areas of application, including environmental scientists and those active in the clinical, pharmaceutical and bioanalytical fields.

Author : Kommer Brunt
Publisher : Unknown
Page : 178 pages
File Size : 52,7 Mb
Release : 1980
Category : Electronic
ISBN : UCAL:B2706908

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Design and optimization of electrochemical detectors for hplc a... by Kommer Brunt Pdf

Author : Karin Isaksson
Publisher : Unknown
Page : 53 pages
File Size : 40,6 Mb
Release : 1987
Category : Chemical detectors
ISBN : 9155421172

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Extensions of Electrochemical Detection in Liquid Chromatography by Use of Multiple Electrodes and by Chemical Reaction Detection by Karin Isaksson Pdf

Author : Joel K. Swadesh
Publisher : CRC Press
Page : 480 pages
File Size : 42,9 Mb
Release : 2000-12-21
Category : Science
ISBN : 9781420042665

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HPLC by Joel K. Swadesh Pdf

Product specifications, regulatory constraints, and tight production schedules impose considerable pressures on separation scientists in industry. The first edition of HPLC: Practical and Industrial Applications helped eliminate the need for extensive library or laboratory research when confronting a problem, an unfamiliar technique, or work in a new area. Its plain language, comprehensive coverage of separation topics, and practical organization made it an accessible and convenient reference manual for anyone working in or just entering the field. Since its publication in 1997, however, much has changed. The areas of mass spectroscopy, electrophoretic separations, and ultra-micro separations have blossomed, focus on quality control has intensified, and the literature has grown significantly. The Second Edition incorporates all of these changes and more. It is now fully current, with chapter supplements that include updated references and discussions of techniques. This book examines analytical HPLC as it is actually used in industry. Whether you are just entering industry, switching from one industry to another, or simply enjoy understanding how things are made, HPLC: Practical and Industrial Applications will help you solve problems and get up to speed in new areas quickly, comfortably, and with a genuine sense of mastery.

Author : A. H. Beckett,J. B. Stenlake
Publisher : A&C Black
Page : 630 pages
File Size : 49,7 Mb
Release : 1988-01-01
Category : Science
ISBN : 0485113236

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Practical Pharmaceutical Chemistry by A. H. Beckett,J. B. Stenlake Pdf

This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.

Author : T. Ryan
Publisher : Springer
Page : 172 pages
File Size : 47,6 Mb
Release : 1984-08-01
Category : Science
ISBN : 0306417278

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Electrochemical Detectors by T. Ryan Pdf

The widely perceived utility of electrochemical detectors in High Performance Liquid Chromatography has focussed attention on a number of disparate aspects of electrochemistry related to their successful design and application. The papers in this volume deal with an extraordinarily wide range of topics but all have the common focus of electrochemical detection as a practical chromatographic tool. While it is certainly not essential to be familiar with the theoretical principles in order to utilize it successfully, the determined user of electrochemical detector will seek to have an understanding of the background. Some of the following pages will provide an excellent grounding as well as pointing the potential user in the direction of proven and possible applications in a variety of fields. The meeting, of which this book is a record, was the fifth event in the biannual Anglo-Czech Symposia in Electrochemistry. The organ izers of that meeting were extremely pleased to welcome a select group of scientists from the J Heyrovsky Institute of Physical Chemistry and Electrochemistry to the meeting, thus continuing a tradition of cooperation and friendship going back over ten years. The contributions of the visitors to the scientific content of the meeting were enthusiastically received and their participation in the informal and social activities can only have furthered the cause of cooperation and good will between our two countries.

Author : Leo M.L. Nollet
Publisher : CRC Press
Page : 1074 pages
File Size : 49,7 Mb
Release : 2000-04-05
Category : Technology & Engineering
ISBN : 082478460X

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Food Analysis by HPLC, Second Edition by Leo M.L. Nollet Pdf

Food Analysis by HPLC, Second Edition presents an exhaustive compilation of analytical methods that belong in the toolbox of every practicing food chemist. Topics covered include biosensors, BMO’s, nanoscale analysis systems, food authenticity, radionuclides concentration, meat factors and meat quality, particle size analysis, and scanning colorimity. It also analyzes peptides, carbohydrates, vitamins, and food additives and contains chapters on alcohols, phenolic compounds, pigments, and residues of growth promoters. Attuned to contemporary food industry concerns, this bestselling classic also features topical coverage of the quantification of genetically modified organisms in food.