Cytochrome P450 Function And Pharmacological Roles In Inflammation And Cancer

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Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer

Anonim

Author : Anonim
Publisher : Academic Press
Page : 506 pages
File Size : 42,9 Mb
Release : 2015-07-23
Category : Medical
ISBN : 9780128031209

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Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer by Anonim Pdf

Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer. Contains contributions from the best authors in the field Ideal reference for those conducting research in cancer, inflammation, cytochrome P450, metabolism, liver disease, and oxidative stress Provides an essential resource for pharmacologists, immunologists, and biochemists

The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases

Kenneth V. Honn,Darryl C. Zeldin

Author : Kenneth V. Honn,Darryl C. Zeldin
Publisher : Springer
Page : 0 pages
File Size : 49,5 Mb
Release : 2019-10-11
Category : Medical
ISBN : 3030216365

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The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases by Kenneth V. Honn,Darryl C. Zeldin Pdf

The Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB). The book in this series will be titled Bioactive Lipids in Cancer, Inflammation and Related Diseases. Topics range from all classes of lipids including prostaglandins, resolvins, spingolipids, P450-derived lipids, endocannabanoids and phospholipids. The focus includes physiology, cell biology, and structural studies in organisms from bacteria to humans and how these studies addressed the role of lipids in various disease i.e. cancer, inflammation, diabetes, obesity, cardiovascular disease and others.

Nutrigenetics

Martin Kohlmeier

Author : Martin Kohlmeier
Publisher : Academic Press
Page : 396 pages
File Size : 47,9 Mb
Release : 2012-12-31
Category : Technology & Engineering
ISBN : 9780123859013

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Nutrigenetics by Martin Kohlmeier Pdf

Nutrigenetics: Applying the Science of Personal Nutrition provides a fully referenced, readable guide to understanding the rationale and importance of nutrigenetic applications and explains why single nutrition recommendations will not fit everybody or even a majority of modern humans. This books explains how genetic variation shapes individual nutrition requirements and sensitivities, presents questions to ask about reported gene-nutrient interactions, and what needs to be done before putting nutrigenetic tests to practical use. This book blends key concepts from the fields of genetics, biochemistry, epidemiology, public health, and clinical medicine to give a rich perspective on the genetically diverse nutritional needs and sensitivities of individuals in health and disease. A steadily increasing number of people order genetic tests to find out what they should eat for better health, well being and performance, and an even greater number asks their healthcare providers about such tests. Most of the currently offered tests are not grounded in current knowledge, often absurdly so, but few professionals can explain why they are misguided. On the other hand, there are more evidence-supported genetic variants that can guide nutrition decisions, but again most healthcare providers know little about them, much less use them in their daily practice. There is a great need for a solidly evidence-based yet accessible book that explains the science of nutrigenetics and provides the tools to evaluate new nutrigenetic tests. Comprehensive coverage of the emerging science of nutritional genetics and its promise for individually tailored nutrition guidance Presents practical examples to enhance comprehension and spur additional research Offers a logical progression from what nutrigenetics is, to its possibilities in enhancing health

Metabolism of Drugs and Other Xenobiotics

Pavel Anzenbacher,Ulrich M. Zanger

Author : Pavel Anzenbacher,Ulrich M. Zanger
Publisher : John Wiley & Sons
Page : 755 pages
File Size : 50,6 Mb
Release : 2012-05-29
Category : Medical
ISBN : 9783527329038

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Metabolism of Drugs and Other Xenobiotics by Pavel Anzenbacher,Ulrich M. Zanger Pdf

A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

Vitamin D

David Feldman,J. Wesley Pike,Roger Bouillon,Edward Giovannucci,David Goltzman,Martin Hewison

Author : David Feldman,J. Wesley Pike,Roger Bouillon,Edward Giovannucci,David Goltzman,Martin Hewison
Publisher : Academic Press
Page : 1266 pages
File Size : 44,8 Mb
Release : 2017-12-18
Category : Science
ISBN : 9780128099643

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Vitamin D by David Feldman,J. Wesley Pike,Roger Bouillon,Edward Giovannucci,David Goltzman,Martin Hewison Pdf

Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease. This collection represents a who’s who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus. Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles Chapter authors include the most prominent and well-published names in the field Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis and vitamin D deficiency Presents a clinical focus on disorders, analogs, cancer, immunity, inflammation, disease and therapeutic applications

How Tobacco Smoke Causes Disease

Anonim

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 47,6 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Drug Metabolism in Diseases

Wen Xie

Author : Wen Xie
Publisher : Academic Press
Page : 294 pages
File Size : 43,9 Mb
Release : 2016-09-12
Category : Medical
ISBN : 9780128029633

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Drug Metabolism in Diseases by Wen Xie Pdf

Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology. Written and edited by leaders in drug metabolism from academia and industry Covers important topics, such as pharmacogenomics, drug metabolism in transplant patients, xenobiotic receptors, drug metabolism in geriatric and pediatric populations, and more Highlights topics of importance in drug discovery and development, and for safe and effective drug use in the clinic

Biochemistry of Lipids, Lipoproteins and Membranes

Neale Ridgway,Roger McLeod

Author : Neale Ridgway,Roger McLeod
Publisher : Elsevier
Page : 612 pages
File Size : 49,8 Mb
Release : 2015-07-24
Category : Science
ISBN : 9780444634498

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Biochemistry of Lipids, Lipoproteins and Membranes by Neale Ridgway,Roger McLeod Pdf

Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six, contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology. It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. It is a valuable tool for advanced graduate students and researchers who are interested in exploring lipid biology in more detail, and includes overviews of lipid biology in both prokaryotes and eukaryotes, while also providing fundamental background on the subsequent descriptions of fatty acid synthesis, desaturation and elongation, and the pathways that lead the synthesis of complex phospholipids, sphingolipids, and their structural variants. Also covered are sections on how bioactive lipids are involved in cell signaling with an emphasis on disease implications and pathological consequences. Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry References from current literature will be included in each chapter to facilitate more in-depth study Key concepts are supported by figures and models to improve reader understanding Chapters provide historical perspective and current analysis of each topic

Bentham Briefs in Biomedicine and Pharmacotherapy Oxidative Stress and Natural Antioxidants

Pardeep Kaur,Rajendra G. Mehta, Robin, Tarunpreet Singh Thind, Saroj Arora

Author : Pardeep Kaur,Rajendra G. Mehta, Robin, Tarunpreet Singh Thind, Saroj Arora
Publisher : Bentham Science Publishers
Page : 502 pages
File Size : 53,6 Mb
Release : 2021-09-29
Category : Medical
ISBN : 9789814998888

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Bentham Briefs in Biomedicine and Pharmacotherapy Oxidative Stress and Natural Antioxidants by Pardeep Kaur,Rajendra G. Mehta, Robin, Tarunpreet Singh Thind, Saroj Arora Pdf

Bentham Briefs in Biomedicine and Pharmacotherapy brings new trends and techniques in pharmacology and medical biochemistry to the forefront through unique volumes. Each volume provides a brief review of selected topics, written by scientific experts. The book series is essential reading for graduate students and researchers in pharmacology and life sciences as well as medical professionals seeking knowledge for research oriented projects. The first volume, Oxidative Stress and Natural Antioxidants, is a compilation of articles about free radicals (which are extremely reactive, short-lived molecules with unpaired electron valency), and antioxidants (which are stabilizing agents of free radicals in the body). The volume presents 17 chapters on the biochemistry of free radicals and antioxidants, with contributions from over 60 scientists. Readers will understand the basic and clinical aspects of free radical biomedicine, the role of antioxidants in neutralizing free radicals through physiological homeostasis, as well as the range of natural compounds which can be used to combat oxidative stress. The chapters also cover special topics such as recent advances in preparation methods of antioxidants, and industrial applications of antioxidants. The range of topics in this volume provide a consolidated reference for a broad set of readers on the subject.

Holland-Frei Cancer Medicine

Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 48,9 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Liver Pathophysiology

Pablo Muriel

Author : Pablo Muriel
Publisher : Academic Press
Page : 914 pages
File Size : 44,9 Mb
Release : 2017-03-02
Category : Medical
ISBN : 9780128043219

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Liver Pathophysiology by Pablo Muriel Pdf

Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.

Handbook of Pharmacogenomics and Stratified Medicine

Sandosh Padmanabhan

Author : Sandosh Padmanabhan
Publisher : Academic Press
Page : 1119 pages
File Size : 45,7 Mb
Release : 2014-04-28
Category : Science
ISBN : 9780123868831

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Handbook of Pharmacogenomics and Stratified Medicine by Sandosh Padmanabhan Pdf

Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details. Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics Covers newer technologies– next generation sequencing, proteomics, metabolomics Provides information on animal models, lymphoblastoid cell lines, stem cells Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues Includes chapters on the global implications of pharmacogenomics

Comprehensive Hypertension E-Book

Gregory Y. H. Lip,John E. Hall

Author : Gregory Y. H. Lip,John E. Hall
Publisher : Elsevier Health Sciences
Page : 1247 pages
File Size : 44,8 Mb
Release : 2007-06-28
Category : Medical
ISBN : 9780323070676

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Comprehensive Hypertension E-Book by Gregory Y. H. Lip,John E. Hall Pdf

Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Bioactive Food as Dietary Interventions for Cardiovascular Disease

Ronald Ross Watson,Victor R. Preedy

Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Page : 722 pages
File Size : 42,5 Mb
Release : 2012-10-23
Category : Health & Fitness
ISBN : 9780123964854

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Bioactive Food as Dietary Interventions for Cardiovascular Disease by Ronald Ross Watson,Victor R. Preedy Pdf

One major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling evidence to suggest that oxidative stress is implicated in the physiology of several major cardiovascular diseases including heart failure and increased free radical formation and reduced antioxidant defences. Studies indicate bioactive foods reduce the incidence of these conditions, suggestive of a potential cardioprotective role of antioxidant nutrients. Bioactive Food as Dietary Interventions for Cardiovascular Disease investigates the role of foods, herbs and novel extracts in moderating the pathology leading to cardiovascular disease. It reviews existing literature, and presents new hypotheses and conclusions on the effects of different bioactive components of the diet. Addresses the most positive results from dietary interventions using bioactive foods to impact cardiovascular disease Documents foods that can affect metabolic syndrome and other related conditions Convenient, efficient and effective source that allows readers to identify potential uses of compounds - or indicate those compounds whose use may be of little or no health benefit Associated information can be used to understand other diseases that share common etiological pathways

Herbal Medicine

Iris F. F. Benzie,Sissi Wachtel-Galor

Author : Iris F. F. Benzie,Sissi Wachtel-Galor
Publisher : CRC Press
Page : 500 pages
File Size : 46,9 Mb
Release : 2011-03-28
Category : Health & Fitness
ISBN : 9781439807163

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Herbal Medicine by Iris F. F. Benzie,Sissi Wachtel-Galor Pdf

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Cytochrome P450 Function And Pharmacological Roles In Inflammation And Cancer

Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer by Anonim Pdf

The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases by Kenneth V. Honn,Darryl C. Zeldin Pdf

Nutrigenetics by Martin Kohlmeier Pdf

Metabolism of Drugs and Other Xenobiotics by Pavel Anzenbacher,Ulrich M. Zanger Pdf

Vitamin D by David Feldman,J. Wesley Pike,Roger Bouillon,Edward Giovannucci,David Goltzman,Martin Hewison Pdf

How Tobacco Smoke Causes Disease by Anonim Pdf

Drug Metabolism in Diseases by Wen Xie Pdf

Biochemistry of Lipids, Lipoproteins and Membranes by Neale Ridgway,Roger McLeod Pdf

Bentham Briefs in Biomedicine and Pharmacotherapy Oxidative Stress and Natural Antioxidants by Pardeep Kaur,Rajendra G. Mehta, Robin, Tarunpreet Singh Thind, Saroj Arora Pdf

Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Liver Pathophysiology by Pablo Muriel Pdf

Handbook of Pharmacogenomics and Stratified Medicine by Sandosh Padmanabhan Pdf

Comprehensive Hypertension E-Book by Gregory Y. H. Lip,John E. Hall Pdf

Bioactive Food as Dietary Interventions for Cardiovascular Disease by Ronald Ross Watson,Victor R. Preedy Pdf

Herbal Medicine by Iris F. F. Benzie,Sissi Wachtel-Galor Pdf

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