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Author : Hugo C. Pribor,George Morrell,George H. Scherr
Publisher : Unknown
Page : 216 pages
File Size : 52,8 Mb
Release : 1980
Category : Medical
ISBN : UOM:39015004440668
Author : William E. Evans,Jerome J. Schentag,William J. Jusko
Publisher : Applied Therapeutics, Incorporated
Page : 1236 pages
File Size : 53,9 Mb
Release : 1992
Category : Chemotherapy
ISBN : UOM:39015013811040
The Third Edition of Applied Pharmacokinetics remains the gold standard by which all other clinical pharmacokinetics texts are measured. Written by leading pharmacokinetics researchers and practitioners, this book is the most advanced kinetics reference available. All chapters have been extensively updated or completely rewritten for this edition, and six new chapters have been added on pharmacodynamics, pharmacogenetics, pharmacokinetic considerations in the obese, dietary influences on drug disposition, zidovudine, and corticosteroids. Each chapter is tightly focused on the most important concepts and issues. Chapters on specific drugs are organized in a consistent format for quick, easy information retrieval. Major subheadings include Clinical Pharmacokinetics, Pharmacodynamics, Clinical Application of Pharmacokinetic Data, Analytical Methods, and Prospectus.
Author : Michael E. Burton
Publisher : Lippincott Williams & Wilkins
Page : 924 pages
File Size : 54,7 Mb
Release : 2006
Category : Medical
ISBN : 0781744318
The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy. This edition includes case studies that apply concepts to actual patient problems. New chapters cover tacrolimus, mycophenolic acid, sirolimus, antipsychotics, and critical evaluation of therapeutic drug monitoring methods. Other new features include more drawings and reference tables and an appendix on outcome studies with therapeutic drug monitoring.
Author : Therapeutic Drug Monitoring and Toxicology Laboratory Improvement Program Committee,American Association for Clinical Chemistry
Publisher : Amer Assn for Clinical Chemistry
Page : 143 pages
File Size : 45,9 Mb
Release : 1994-01-01
Category : Drug monitoring
ISBN : 0915274701
The AACC DRUG MONITORING DATA POCKET GUIDE is an up-to-date, easy-to-use source of information on the most commonly measured therapeutic drugs in today's clinical laboratory. It provides a quick reference to drug pharmacokinetics, analysis & sample handling. References are provided for those needing more detail. The guide will be very useful for clinical scientists involved in therapeutic drug monitoring & as an education aid. 1994, 4 1/2 x 6 Softcover, ISBN 0-915274-70-1, $15, Order #625.
Author : Catherine A. Hammett-Stabler,Amitava Dasgupta
Publisher : Unknown
Page : 241 pages
File Size : 46,8 Mb
Release : 2007-01-01
Category : Drug monitoring
ISBN : 1594250758
Author : Amitava Dasgupta,Matthew Krasowski
Publisher : Academic Press
Page : 382 pages
File Size : 43,7 Mb
Release : 2019-09-14
Category : Science
ISBN : 9780128158500
Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab. Serves as a ready resource of information for commonly monitored drugs Presents a useful, quick guide for those making decisions related to monitoring and interpretation of results Provides concise, easily digestible content for clinical laboratory scientists, toxicologists and clinicians
Author : Daniel M. Baer,William R. Dito
Publisher : Unknown
Page : 418 pages
File Size : 44,7 Mb
Release : 1981
Category : Medical
ISBN : UOM:39015006016458
Author : Ronald D. Schoenwald
Publisher : CRC Press
Page : 430 pages
File Size : 45,8 Mb
Release : 2002-03-06
Category : Medical
ISBN : 9781420010084
Pharmacokinetics has evolved from its origin into a complex discipline with numerous subspecialties and applications in patient management, drug development, and regulatory issues. This expansion has made it difficult for any one individual to become a full-fledged expert in all areas. Fulfilling the need for a wide-ranging guide to the many existi
Author : Gerald E. Schumacher
Publisher : McGraw-Hill/Appleton & Lange
Page : 712 pages
File Size : 45,9 Mb
Release : 1995
Category : Medical
ISBN : UOM:39015033266571
Author : Seth Kwabena Amponsah,Yashwant V. Pathak
Publisher : Springer Nature
Page : 384 pages
File Size : 51,5 Mb
Release : 2022-10-25
Category : Medical
ISBN : 9783031123986
This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges
Author : Peter Elliott (B.Pharm.)
Publisher : Unknown
Page : 99 pages
File Size : 45,7 Mb
Release : 1990
Category : Drugs
ISBN : 0646007610
Author : Steven H.Y. Wong
Publisher : Routledge
Page : 521 pages
File Size : 44,9 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9781351408479
This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.
Author : Mohsen A. Hedaya
Publisher : CRC Press
Page : 595 pages
File Size : 55,7 Mb
Release : 2012-02-09
Category : Medical
ISBN : 9781439850756
Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It is therefore vital to those engaged in the discovery, development, and preclinical and clinical evaluation of drugs, as well as practitioners involved in the clinical use of drugs. Using different approaches accessible to
Author : William Clarke,Amitava Dasgupta
Publisher : Elsevier
Page : 376 pages
File Size : 47,5 Mb
Release : 2016-07-21
Category : Medical
ISBN : 9780128020524
Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window
Author : Amitava Dasgupta
Publisher : Academic Press
Page : 469 pages
File Size : 40,5 Mb
Release : 2012-06-07
Category : Medical
ISBN : 9780123854681
Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. Includes both the technical and clinical issues associated with therapeutic drug monitoring Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques