Electrochemical Detection In Hplc And Hpce

Author : Ian N. Acworth
Publisher : VSP
Page : 396 pages
File Size : 44,9 Mb
Release : 1997
Category : Science
ISBN : 9067642320

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Coulometric Electrode Array Detectors for Hplc by Ian N. Acworth Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.

Author : P. T. Kissinger
Publisher : Unknown
Page : 128 pages
File Size : 50,6 Mb
Release : 2024-06-26
Category : Electronic
ISBN : 0824700198

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Electrochemical Detection in HPLC and HPCE by P. T. Kissinger Pdf

Author : Robert J Flanagan,David Perrett,Robin Whelpton
Publisher : Royal Society of Chemistry
Page : 244 pages
File Size : 54,7 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847550729

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Electrochemical Detection in HPLC by Robert J Flanagan,David Perrett,Robin Whelpton Pdf

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Author : T. Ryan
Publisher : Springer Science & Business Media
Page : 171 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461593973

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Electrochemical Detectors by T. Ryan Pdf

The widely perceived utility of electrochemical detectors in High Performance Liquid Chromatography has focussed attention on a number of disparate aspects of electrochemistry related to their successful design and application. The papers in this volume deal with an extraordinarily wide range of topics but all have the common focus of electrochemical detection as a practical chromatographic tool. While it is certainly not essential to be familiar with the theoretical principles in order to utilize it successfully, the determined user of electrochemical detector will seek to have an understanding of the background. Some of the following pages will provide an excellent grounding as well as pointing the potential user in the direction of proven and possible applications in a variety of fields. The meeting, of which this book is a record, was the fifth event in the biannual Anglo-Czech Symposia in Electrochemistry. The organ izers of that meeting were extremely pleased to welcome a select group of scientists from the J Heyrovsky Institute of Physical Chemistry and Electrochemistry to the meeting, thus continuing a tradition of cooperation and friendship going back over ten years. The contributions of the visitors to the scientific content of the meeting were enthusiastically received and their participation in the informal and social activities can only have furthered the cause of cooperation and good will between our two countries.

Author : I.H. Acworth,M. Naoi,Hasan Parvez,S. Parvez
Publisher : CRC Press
Page : 393 pages
File Size : 53,6 Mb
Release : 2024-01-26
Category : Science
ISBN : 9781466563711

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Coulometric Electrode Array Detectors for HPLC by I.H. Acworth,M. Naoi,Hasan Parvez,S. Parvez Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.

Author : Hilmer Sorensen,Susanne Sorensen,Charlotte Bjergegaard,Soren Michaelsen
Publisher : Royal Society of Chemistry
Page : 489 pages
File Size : 47,6 Mb
Release : 2007-10-31
Category : Technology & Engineering
ISBN : 9781847550521

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Chromatography and Capillary Electrophoresis in Food Analysis by Hilmer Sorensen,Susanne Sorensen,Charlotte Bjergegaard,Soren Michaelsen Pdf

In the rapidly developing field of analysis it is important to be aware of the newest methods within available techniques. Chromatography and Capillary Electrophoresis in Food Analysis describes chromatographic and electrophoretic principles and procedures for analyses of various amphiphilic and hydrophilic biomolecules, particularly for food analysis. Providing basic information, including general sample preparation, the book then goes on to describe individual analytical methods and exemplify the strategy and methodologies employed for the analyses. The theory necessary to understand the methods and interpretation of results is also included, as are numerous detailed instructions on experiments. Tables, figures and references are included to give a complete picture. Chromatography and Capillary Electrophoresis in Food Analysis will be especially valuable for students and more experienced researchers interested in analysis of natural products, both inside and outside the field of food chemistry.

Author : Claude Reiss,Simone Parvez,Gilles Labbe
Publisher : VSP
Page : 590 pages
File Size : 40,5 Mb
Release : 1998-02
Category : Science
ISBN : 9067642789

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Advances in Molecular Toxicology by Claude Reiss,Simone Parvez,Gilles Labbe Pdf

Molecular toxicology is on the way to setting a new standard in toxic risk assessment, with the powerful help of concepts and methods developed in the fields of molecular and cellular biology. The methods of molecular toxicology are endowed with qualities not always secured in more traditional approaches to toxicity assessment. These methods are easily standardized, reliable, reproducible and require only tiny amounts of the xenobiotic. They are much simpler, faster and less costly than current tests on animals and can be implemented with modest laboratory resources. This volume of Advances in Molecular Toxicology represents a collection of invited papers presented at the First European Workshop on Molecular Toxicology in Sophia Antipolis, France, The book covers 8 selected topics in molecular toxicology. The first two are devoted to ''physics'', dealing respectively with advanced instrumentation enabling location and quantification of xenobiotics in cells and organs with ultimate precision, and computer-assisted assessment of risk (QSAR). A comprehensive and up-to-date survey of molecular toxicology in the pharmaceutical industry is contributed by a pioneer in this field. The third section addresses the effect of xenobiotics on cell-cycle actors. Sections 4--6 deal with molecular toxicology in skin, kidney, nerve, liver and pancreatic cells. The last two sections describe methods to probe DNA damage and repair, and immunotoxicity.

Author : Alberto Escarpa,María Cristina González,Miguel Ángel López
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 40,6 Mb
Release : 2015-07-15
Category : Science
ISBN : 9781118682968

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Agricultural and Food Electroanalysis by Alberto Escarpa,María Cristina González,Miguel Ángel López Pdf

Agricultural and Food Electroanalysis offers a comprehensive rationale of electroanalysis, revealing its enormous potential in agricultural food analysis. A unique approach is used which fills a gap in the literature by bringing in applications to everyday problems. This timely text presents in-depth descriptions about different electrochemical techniques following their basic principles, instrumentation and main applications. Such techniques offer invaluable features such as inherent miniaturization, high sensitivity and selectivity, low cost, independence of sample turbidity, high compatibility with modern technologies such as microchips and biosensors, and the use of exciting nanomaterials such as nanoparticles, nanotubes and nanowires. Due to the advantages that modern electroanalytical techniques bring to food analysis, and the huge importance and emphasis given today to food quality and safety, this comprehensive work will be an essential read for professionals and researchers working in analytical laboratories and development departments, and a valuable guide for students studying for careers in food science, technology and chemistry.

Author : R. Andrew Shalliker
Publisher : CRC Press
Page : 308 pages
File Size : 48,7 Mb
Release : 2011-12-14
Category : Science
ISBN : 9781420008487

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Hyphenated and Alternative Methods of Detection in Chromatography by R. Andrew Shalliker Pdf

Widely employed for separating and detecting chemicals in solution, separation techniques are most often applied in tandem, subsequently referred to as hyphenated methods. Hyphenated and Alternative Methods of Detection in Chromatography details the development and application of mass spectral detection techniques coupled with gas phase and liquid

Author : Richard G. Cutler
Publisher : World Scientific
Page : 872 pages
File Size : 43,7 Mb
Release : 2003
Category : Family & Relationships
ISBN : 9789812775733

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Critical Reviews of Oxidative Stress and Aging by Richard G. Cutler Pdf

This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.

Author : Craig Banks,Roger Mortimer,Steven McIntosh
Publisher : Royal Society of Chemistry
Page : 220 pages
File Size : 51,6 Mb
Release : 2015-11-19
Category : Electrochemistry
ISBN : 9781849739801

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Electrochemistry by Craig Banks,Roger Mortimer,Steven McIntosh Pdf

The Specialist Periodical Report Electrochemistry presents comprehensive and critical reviews in all aspects of the field, with contributions from across the globe, providing the reader with an informed digest of the most important research currently carried out in this field. Re-launching in 2015 with a new editorial team, Volume 13 returns to its roots and provides a wide range of topics written by leading experts researching at the forefront and heart of electrochemistry. The book covers topics such as control and structural analysis, and combines different approaches on utilizing light as a source for materials science. This volume is a key reference in the field of electrochemistry, allowing readers to become easily acquainted with the latest research trends.

Author : Joel K. Swadesh
Publisher : CRC Press
Page : 396 pages
File Size : 46,5 Mb
Release : 1996-11-26
Category : Medical
ISBN : 0849326826

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HPLC by Joel K. Swadesh Pdf

High performance liquid chromatography (HPLC) is a technique used in diverse laboratory and industrial settings for the separation of components of complex mixtures. HPLC: Practical and Industrial Applications is a trouble-shooting, problem-solving guide for scientists, engineers, and technicians who use HPLC in their day-to-day work. It provides the answers to specific problems and includes practical case studies. This case history approach to chromatography is an effective teaching tool and clearly illustrates how to use techniques such as reversed phase chromatography, ion exchange chromatography, gel permeation chromatography, and capillary electrophoresis. The book is organized to facilitate rapid understanding for those working with a particular area of chromatography: Introduces the reader to instrumentation, reviews basic chromatographic theory, and presents a brief survey of absorbance fluorescence and refractive index detectors. Provides a broad view of the role of the analytical laboratory in an industrial organization. Offers suggestions on optimizing the utilization of personnel and work flow in the laboratory. Covers process sampling and analysis · Describes process chromatography. The remaining chapters discuss specialties within separations technology, including an outline of the key features of each technique, a thorough bibliography, a list of precedents, and detailed examples of one or more applications presented from the viewpoint of industrial and basic scientists. Specialty detectors are also described. HPLC: Practical and Industrial Applications is an essential reference for those working in the industrial sector, as well as scientists, students, technicians interested in learning HPLC methods.

Author : Z. El Rassi
Publisher : Elsevier
Page : 665 pages
File Size : 47,6 Mb
Release : 1994-11-11
Category : Science
ISBN : 008085866X

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Carbohydrate Analysis by Z. El Rassi Pdf

Carbohydrates and glycoconjugates play an important role in several life processes. The wide variety of carbohydrate species and their inherent polydispersity and heterogeneity require separation techniques of high resolving power and high selectivity such as high performance liquid chromatography (HPLC) and capillary electrophoresis (HPCE). In the last decade HPLC, and recently HPCE methods have been developed for the high resolution and reproducible quantitation of carbohydrates. Despite the importance of these two column separation technologies in the area of carbohydrates, no previous book describes specialized methods for the separation, purification and detection of carbohydrates and glycoconjugates by HPLC and HPCE. Therefore, the objective of the present book is to provide a comprehensive review of carbohydrate analysis by HPLC and HPCE by covering analytical and preparative separation techniques for all classes of carbohydrates including mono- and disaccharides; linear and cyclic oligosaccharides; branched heterooligosaccharides (e.g., glycans, plant-derived oligosaccharides); glycoconjugates (e.g., glycolipids, glycoproteins); carbohydrates in food and beverage; compositional carbohydrates of polysaccharides; carbohydrates in biomass degradation; etc. The book will be of interest to a wide audience, including analytical chemists and biochemists, carbohydrate, glycoprotein and glycolipid chemists, molecular biologists, biotechnologists, etc. It will also be a useful reference work for both the experienced analyst and the newcomer as well as for users of HPLC and HPCE, graduates and postdoctoral students.

Author : Kenneth Hensley,Robert A. Floyd
Publisher : Springer Science & Business Media
Page : 212 pages
File Size : 44,7 Mb
Release : 2008-02-06
Category : Medical
ISBN : 9781592594245

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Methods in Biological Oxidative Stress by Kenneth Hensley,Robert A. Floyd Pdf

Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few. Because of the centrality of oxidative processes to normal and abnormal tissue function, it has become imperative to develop appropriate analytical techniques to facilitate the quantitation of significant reactants. Without advances in methodology, corresponding advances in our knowledge of underlying biochemical events will be necessarily limited. Drs. Hensley and Floyd have done an outstanding job of assembling the work of world-class experts into Methods in Biological Oxidative Stress. The contributors have presented concise, yet thorough, descriptions of the state-of-the-art methods that any investigator working in the field needs to access. Mannfred A. Hollinger v Preface Free radicals and reactive oxidizing agents were once ignored as biochemical entities not worth close scrutiny, but are now recognized as causes or contributing factors in dozens, if not hundreds, of disease states. In addition, free radical metabolisms of xenobiotics have become increasingly important to pharmacologists. Accordingly, the need has arisen to accurately quantify reactive oxygen species and their byproducts. Methods in Biological Oxidative Stress is practical in scope, providing the details of up-to-date techniques for measuring oxidative stress and detecting oxidizing agents both in vitro and in vivo. The contributors are recognized experts in the field of oxidative stress who have developed novel strategies for studying biological oxidations.

Author : Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 41,6 Mb
Release : 2006-03-20
Category : Science
ISBN : 9780387252407

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Metabolome Analyses: by Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre Pdf

Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems.