Development And Application Of High Performance Liquid Chromatography With Electrochemical Detection

Author : William R. LaCourse
Publisher : Wiley-Interscience
Page : 360 pages
File Size : 48,9 Mb
Release : 1997-08-18
Category : Science
ISBN : UOM:39015050267783

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Pulsed Electrochemical Detection in High-Performance Liquid Chromatography by William R. LaCourse Pdf

A reliable, comprehensive, relevant view of HPLC and its applications The development of HPLC-PED represents the successful marriage of two powerful analytical technologies and has resulted in the best technique for sensitive and direct detection of biological compounds with poor optical detection properties. PED has been used extensively for the determination of carbohydrates and other polar aliphatic compounds, and as a result, numerous methods have been developed to enable the analysis of a wide variety of samples. Over the years, many articles, anecdotal information, and misinformation have permeated the scientific community, with the possible consequence of confusion or uncertainty with regard to PED on the part of the analyst. Pulsed Electrochemical Detection in High-Performance Liquid Chromatography presents a reliable, comprehensive, and relevant review of HPLC-PED and its applications. The book is divided into three major parts: background material necessary for a more thorough understanding of the principles and relevance of PED; an in-depth discussion of PED using voltammetry and other electroanalytical techniques and presenting the advantages, applicability, and optimization of all existing PED waveforms; and practical aspects of HPLC-PED, including a summary of the major applications and a look at future developments in the technique. Appendices include a pulsed voltammetry (PV) program specifically written to optimize pulsed amperometric detection (PAD) waveforms and all the known applications, categorized and listed in tabular form. For analytical chemists; biochemists; carbohydrate chemists; biotechnologists; undergraduate, graduate, and postdoctoral students; and lab technicians working in a range of areas including the pharmaceutical, medical, and food and beverage industries, this eminently readable guide is the first reliable book-length treatment of how to use PED coupled with HPLC.

Author : Walter Lowry Candill
Publisher : Unknown
Page : 398 pages
File Size : 48,9 Mb
Release : 1983
Category : Electrochemical apparatus
ISBN : IND:39000000774252

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Development and Application of High Performance Liquid Chromatography with Electrochemical Detection by Walter Lowry Candill Pdf

Author : R. Andrew Shalliker
Publisher : CRC Press
Page : 311 pages
File Size : 43,8 Mb
Release : 2011-12-14
Category : Science
ISBN : 9780849390777

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Hyphenated and Alternative Methods of Detection in Chromatography by R. Andrew Shalliker Pdf

Widely employed for separating and detecting chemicals in solution, separation techniques are most often applied in tandem, subsequently referred to as hyphenated methods. Hyphenated and Alternative Methods of Detection in Chromatography details the development and application of mass spectral detection techniques coupled with gas phase and liquid phase chromatographies. With contributions from experts in a variety of fields, as evidenced by the range of topics, the book describes the advantages and disadvantages of various separation techniques and addresses methods for cutting-edge applications such as proteomics research. Specifically, this book covers: The development of the LC-NMR and its application in chromatographic science, particularly in relation to the analysis of natural and environmental samples and in the study of reaction monitoring, biosynthetic analysis, and structural elucidation The application of LC-ICP in biological samples for the speciation of organoarsenic and organoselenium compounds; metal complexes in microorganisms, plants, and foods of plant origin; human body fluids and tissues; and in the detection of chemical warfare agents Electrochemical detection in liquid chromatography, system optimization, and applications in the analysis of flavonoids The use of chemiluminescence for microcolumn and capillary methods of separation The process of employing multidimensional separation methods as a means of identifying components in complex samples A detailed reference for those starting out in the field, this book also suits those who are more experienced yet require assistance in new directions. It is an ideal reference for senior undergraduate and postgraduate students wishing to supplement their learning experience. Containing over 800 references, this book is an excellent source of information within the field of hyphenated methods of chromatographic analysis.

Author : R. Bruce Holman,Alan J. Cross,Michael H. Joseph
Publisher : Unknown
Page : 392 pages
File Size : 50,6 Mb
Release : 1993-06-22
Category : Medical
ISBN : UOM:39015031803912

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High Performance Liquid Chromatography in Neuroscience Research by R. Bruce Holman,Alan J. Cross,Michael H. Joseph Pdf

General Editor: A.D. Smith High Performance Liquid Chromatography in Neuroscience Research Edited by R. Bruce Holman, Alan J. Cross and Michael H. Joseph This volume in the Handbook Series begins with a succinct introduction to the principles of High Performance Liquid Chromatography (HPLC) and to the principles of methods development for neuroscience application. The primary emphasis of the book is on detailed and functional description of methods for a wide range of specific groups of neurochemicals, with particular emphasis on the analysis of neurotransmitters and related compounds. The final chapter reviews the application of HPLC to the analysis of central nervous system (CNS)-active drugs. Each chapter is written by experts in their fields. As well as providing a brief overview of the choice of methodologies, they focus on specific methods to provide the maximum amount of practical information based on personal experience, illustrated by material from the analysis of real biological samples.

Author : Csaba Horváth
Publisher : Elsevier
Page : 332 pages
File Size : 50,8 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483261881

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High-Performance Liquid Chromatography by Csaba Horváth Pdf

High-Performance Liquid Chromatography: Advances and Perspectives, Volume 4 is an authoritative publication that deals with the fundamentals, instrumentation, and applications of high-performance liquid chromatography. The volume contains articles on practical aspects of reversed-phase chromatography in the study of biopolymer separations; characterization of stationary phases and the development of various packing materials; electrochemical detection; and the fundamentals of chromatographic behavior of large molecules. Chromatographers, chemists, and researchers in the field of chemical analysis will find this book an interesting read.

Author : Robert James Flanagan,David Perrett,Robin Whelpton
Publisher : Royal Society of Chemistry
Page : 258 pages
File Size : 53,9 Mb
Release : 2005
Category : Science
ISBN : 0854045325

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Electrochemical Detection in HPLC by Robert James Flanagan,David Perrett,Robin Whelpton Pdf

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Author : W.J. Lough,I.W. Wainer
Publisher : CRC Press
Page : 292 pages
File Size : 48,8 Mb
Release : 1995-09-30
Category : Science
ISBN : 0751400769

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High Performance Liquid Chromatography by W.J. Lough,I.W. Wainer Pdf

High performance liquid chromatography (HPLC) has long been recognized as one of the most useful and versatile analytical techniques. It has now progressed from being a highly expensive method of analysis to a routine technique with wide applications. Consequently there is a requirement in many chemistry and chemistry-related courses for students to acquire a detailed understanding of the principles and practice of HPLC. Written in a manner suitable for undergraduate students studying analytical chemistry and learning about chromatographic analytical techniques applied to pharmaceutical analysis, biochemistry and related disciplines, High-performance Liquid Chromatography: Fundamental Principles and Practice introduces the fundamentals of HPLC. Loosely structured in three parts, the text begins with a thorough introduction of the subject and then progresses through the essential knowledge of the instrumentation needed for HPLC. The final part covers with the applications of HPLC in real-world situations. Developed by a team of international experts from a wide cross-section of disciplines, the text is relevant to a wide range of courses.

Author : Ian N. Acworth
Publisher : VSP
Page : 396 pages
File Size : 49,5 Mb
Release : 1997
Category : Science
ISBN : 9067642320

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Coulometric Electrode Array Detectors for Hplc by Ian N. Acworth Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.

Author : Phyllis R. Brown,Richard A. Hartwick
Publisher : Wiley-Interscience
Page : 710 pages
File Size : 53,6 Mb
Release : 1989-01-19
Category : Science
ISBN : UOM:39015038990811

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High Performance Liquid Chromatography by Phyllis R. Brown,Richard A. Hartwick Pdf

Detectors for Liquid Chromatography Edited by Edward S. Yeung Written by an expert in the field, this comprehensive guide explains the basic principles behind detector response instrumentation and selected applications. Early chapters cover absorption detectors for high performance liquid chromatography, FTIR detection, indirect absorbance detectors, fluorometric detection, and polarimetric detectors. Coverage continues with detection based on electrical and electrochemical measurements, mass spectrometry as an online detector for HPLC, and miscellaneous methods. 1986 0 471-82169-1 366 pp. Small Bore High Performance Liquid Chromatography Edited by Raymond R. W. Scott A state-of-the-art guide that demonstrates how to design, construct, and pack optimized small bore columns, the center of any chromatography system. Case examples show the use of these columns for high resolution, very fast analysis, and special methods for molecular weight determinations. Applications from a wide range of industrial and forensic analyses aid in developing sophistication in a number of useful techniques. The book provides essential information on topics such as calculating the minimum column radius, detectors, and molecular diffusion. Includes 92 illustrations and 14 tables to enhance explanations of microbore HPLC methods. 1984 0 471-80052-X 271 pp. Reversed-Phase High Performance Liquid Chromatography: Theory, Practice, and Biomedical Applications Ante M. Krstulovic and Phyllis R. Brown Reversed-phase liquid chromatography has increased tremendously in popularity over the past ten years. Estimates show that more than 80% of all HPLC separations are performed using this technique. This book covers both theoretical aspects of RPLC and practical information needed in diverse areas of research; it also contains a review of the RPLC applications in the biomedical/biochemical field, with references and collateral readings. Material is presented in a practical, problem-solving manner and should be immensely useful in theoretical aspects of RPLC and all areas of scientific research, particularly the biomedical/biochemical field, where RPLC has made its largest impact. 1982 0 471-05369-4 296 pp.

Author : Anonim
Publisher : Unknown
Page : 1940 pages
File Size : 50,7 Mb
Release : 2004
Category : Medicine
ISBN : MINN:31951P00992544K

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Author : Anonim
Publisher : Unknown
Page : 1162 pages
File Size : 49,8 Mb
Release : 1986
Category : Aeronautics
ISBN : UIUC:30112075701208

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Scientific and Technical Aerospace Reports by Anonim Pdf

Author : S. Pryde,M.T. Gilbert
Publisher : Springer Science & Business Media
Page : 288 pages
File Size : 43,7 Mb
Release : 1979-01-31
Category : Science
ISBN : 0412142201

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Applications of High Performance Liquid Chromatography by S. Pryde,M.T. Gilbert Pdf

Author : T. Ryan
Publisher : Springer
Page : 172 pages
File Size : 45,9 Mb
Release : 2012-02-16
Category : Science
ISBN : 1461593980

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Electrochemical Detectors by T. Ryan Pdf

The widely perceived utility of electrochemical detectors in High Performance Liquid Chromatography has focussed attention on a number of disparate aspects of electrochemistry related to their successful design and application. The papers in this volume deal with an extraordinarily wide range of topics but all have the common focus of electrochemical detection as a practical chromatographic tool. While it is certainly not essential to be familiar with the theoretical principles in order to utilize it successfully, the determined user of electrochemical detector will seek to have an understanding of the background. Some of the following pages will provide an excellent grounding as well as pointing the potential user in the direction of proven and possible applications in a variety of fields. The meeting, of which this book is a record, was the fifth event in the biannual Anglo-Czech Symposia in Electrochemistry. The organ izers of that meeting were extremely pleased to welcome a select group of scientists from the J Heyrovsky Institute of Physical Chemistry and Electrochemistry to the meeting, thus continuing a tradition of cooperation and friendship going back over ten years. The contributions of the visitors to the scientific content of the meeting were enthusiastically received and their participation in the informal and social activities can only have furthered the cause of cooperation and good will between our two countries.

Author : Anonim
Publisher : Unknown
Page : 1828 pages
File Size : 46,9 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864997

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Cumulated Index Medicus by Anonim Pdf

Author : Lokesh Bhattacharyya,Jeffrey S. Rohrer
Publisher : John Wiley & Sons
Page : 421 pages
File Size : 40,7 Mb
Release : 2012-02-10
Category : Medical
ISBN : 9781118146996

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Applications of Ion Chromatography for Pharmaceutical and Biological Products by Lokesh Bhattacharyya,Jeffrey S. Rohrer Pdf

This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components.