Pulsed Electrochemical Detection In High Performance Liquid Chromatography

Author : William R. LaCourse
Publisher : Wiley-Interscience
Page : 360 pages
File Size : 45,6 Mb
Release : 1997-08-18
Category : Science
ISBN : UOM:39015050267783

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Pulsed Electrochemical Detection in High-Performance Liquid Chromatography by William R. LaCourse Pdf

A reliable, comprehensive, relevant view of HPLC and its applications The development of HPLC-PED represents the successful marriage of two powerful analytical technologies and has resulted in the best technique for sensitive and direct detection of biological compounds with poor optical detection properties. PED has been used extensively for the determination of carbohydrates and other polar aliphatic compounds, and as a result, numerous methods have been developed to enable the analysis of a wide variety of samples. Over the years, many articles, anecdotal information, and misinformation have permeated the scientific community, with the possible consequence of confusion or uncertainty with regard to PED on the part of the analyst. Pulsed Electrochemical Detection in High-Performance Liquid Chromatography presents a reliable, comprehensive, and relevant review of HPLC-PED and its applications. The book is divided into three major parts: background material necessary for a more thorough understanding of the principles and relevance of PED; an in-depth discussion of PED using voltammetry and other electroanalytical techniques and presenting the advantages, applicability, and optimization of all existing PED waveforms; and practical aspects of HPLC-PED, including a summary of the major applications and a look at future developments in the technique. Appendices include a pulsed voltammetry (PV) program specifically written to optimize pulsed amperometric detection (PAD) waveforms and all the known applications, categorized and listed in tabular form. For analytical chemists; biochemists; carbohydrate chemists; biotechnologists; undergraduate, graduate, and postdoctoral students; and lab technicians working in a range of areas including the pharmaceutical, medical, and food and beverage industries, this eminently readable guide is the first reliable book-length treatment of how to use PED coupled with HPLC.

Author : Ian N. Acworth
Publisher : VSP
Page : 396 pages
File Size : 53,5 Mb
Release : 1997
Category : Science
ISBN : 9067642320

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Coulometric Electrode Array Detectors for Hplc by Ian N. Acworth Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.

Author : Robert J Flanagan,David Perrett,Robin Whelpton
Publisher : Royal Society of Chemistry
Page : 244 pages
File Size : 45,7 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847550729

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Electrochemical Detection in HPLC by Robert J Flanagan,David Perrett,Robin Whelpton Pdf

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Author : T. Ryan
Publisher : Springer Science & Business Media
Page : 171 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461593973

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Electrochemical Detectors by T. Ryan Pdf

The widely perceived utility of electrochemical detectors in High Performance Liquid Chromatography has focussed attention on a number of disparate aspects of electrochemistry related to their successful design and application. The papers in this volume deal with an extraordinarily wide range of topics but all have the common focus of electrochemical detection as a practical chromatographic tool. While it is certainly not essential to be familiar with the theoretical principles in order to utilize it successfully, the determined user of electrochemical detector will seek to have an understanding of the background. Some of the following pages will provide an excellent grounding as well as pointing the potential user in the direction of proven and possible applications in a variety of fields. The meeting, of which this book is a record, was the fifth event in the biannual Anglo-Czech Symposia in Electrochemistry. The organ izers of that meeting were extremely pleased to welcome a select group of scientists from the J Heyrovsky Institute of Physical Chemistry and Electrochemistry to the meeting, thus continuing a tradition of cooperation and friendship going back over ten years. The contributions of the visitors to the scientific content of the meeting were enthusiastically received and their participation in the informal and social activities can only have furthered the cause of cooperation and good will between our two countries.

Author : Veronika R. Meyer
Publisher : John Wiley & Sons
Page : 434 pages
File Size : 41,9 Mb
Release : 2010-05-17
Category : Science
ISBN : 9780470682180

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Practical High-Performance Liquid Chromatography by Veronika R. Meyer Pdf

Jump into the HPLC adventure! Three decades on from publication of the 1st German edition of Veronika Meyer's book on HPLC, this classic text remains one of the few titles available on general HPLC aimed at practitioners. New sections on the following topics have been included in this fifth edition: Comparison of HPLC with capillary electrophoresis How to obtain peak capacity van Deemter curves and other coherences Hydrophilic interaction chromatography Method transfer Comprehensive two-dimensional HPLC Fast separations at 1000 bar HPLC with superheated water In addition, two chapters on the instrument test and troubleshooting in the appendix have been updated and expanded by Bruno E. Lendi, and many details have been improved and numerous references added. A completely new chapter is presented on quality assurance covering: Is it worth the effort? Verification with a second method Method validation Standard operating procedures Measurement uncertainty Qualifications, instrument test, and system suitability test The quest for quality Reviews of earlier editions "That this text is written by an expert in both the practice and teaching of HPLC is evident from the first paragraph....not only an enjoyable, fascinating and easy read, but a truly excellent text that has and will serve many teachers, students and practitioners very well." —The Analyst “…provides essential information on HPLC for LC practitioners in academia, industry, government, and research laboratories…a valuable introduction." - American Journal of Therapeutics

Author : Semih Otles
Publisher : CRC Press
Page : 544 pages
File Size : 50,7 Mb
Release : 2016-04-19
Category : Science
ISBN : 9781420045673

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Handbook of Food Analysis Instruments by Semih Otles Pdf

Explore the Pros and Cons of Food Analysis InstrumentsThe identification, speciation, and determination of components, additives, and contaminants in raw materials and products will always be a critical task in food processing and manufacturing. With contributions from leading scientists, many of whom actually developed or refined each technique or

Author : Ziad El Rassi
Publisher : Elsevier
Page : 956 pages
File Size : 52,6 Mb
Release : 2021-08-15
Category : Science
ISBN : 9780128245125

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Carbohydrate Analysis by Modern Liquid Phase Separation Techniques by Ziad El Rassi Pdf

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques, Second Edition, presents readers with the various principles of modern liquid phase separation techniques and their contributions to the analysis of complex carbohydrates and glycoconjugates. In a selection of all-new chapters, this fully updated volume covers each technique in detail. The book aims to help analysts solve any of the many practical problems they may face in tackling the analysis of carbohydrates. In addition, it addresses current difficulties that must be resolved in carbohydrate research, thus inspiring further important technological developments to meet these challenges. This is an essential resource for anyone seeking a broad view of the science of carbohydrates and separation techniques. Covers the basic principles of modern liquid phase separation techniques, along with their applications Compiles up-to-date information on the field of carbohydrate analysis, along with updates on separation science Focuses on problems currently faced in carbohydrate analysis and the solutions necessary for further progress

Author : James S. Fritz,Douglas T. Gjerde
Publisher : John Wiley & Sons
Page : 394 pages
File Size : 48,5 Mb
Release : 2009-03-09
Category : Science
ISBN : 9783527626885

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Ion Chromatography by James S. Fritz,Douglas T. Gjerde Pdf

This completely revised and updated fourth edition of the best-selling classic is a thorough treatment of the subject while remaining concise and readable. New additions include capillary electrophoresis, monolithic columns, zwitterion colums, DNA/RNA analysis, fundamentals of the science of IC, and micro methods. The whole is rounded off by handy tables with details on detection or elution conditions, among others.

Author : Lokesh Bhattacharyya,Jeffrey S. Rohrer
Publisher : John Wiley & Sons
Page : 421 pages
File Size : 52,7 Mb
Release : 2012-02-10
Category : Medical
ISBN : 9781118146996

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Applications of Ion Chromatography for Pharmaceutical and Biological Products by Lokesh Bhattacharyya,Jeffrey S. Rohrer Pdf

This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components.

Author : T. Ryan
Publisher : Springer
Page : 172 pages
File Size : 50,5 Mb
Release : 1984-08-01
Category : Science
ISBN : 0306417278

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Electrochemical Detectors by T. Ryan Pdf

The widely perceived utility of electrochemical detectors in High Performance Liquid Chromatography has focussed attention on a number of disparate aspects of electrochemistry related to their successful design and application. The papers in this volume deal with an extraordinarily wide range of topics but all have the common focus of electrochemical detection as a practical chromatographic tool. While it is certainly not essential to be familiar with the theoretical principles in order to utilize it successfully, the determined user of electrochemical detector will seek to have an understanding of the background. Some of the following pages will provide an excellent grounding as well as pointing the potential user in the direction of proven and possible applications in a variety of fields. The meeting, of which this book is a record, was the fifth event in the biannual Anglo-Czech Symposia in Electrochemistry. The organ izers of that meeting were extremely pleased to welcome a select group of scientists from the J Heyrovsky Institute of Physical Chemistry and Electrochemistry to the meeting, thus continuing a tradition of cooperation and friendship going back over ten years. The contributions of the visitors to the scientific content of the meeting were enthusiastically received and their participation in the informal and social activities can only have furthered the cause of cooperation and good will between our two countries.

Author : Melvin V. Koch,Kurt M. VandenBussche,Ray W. Chrisman
Publisher : John Wiley & Sons
Page : 520 pages
File Size : 42,6 Mb
Release : 2007-06-27
Category : Technology & Engineering
ISBN : 9783527610617

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Micro Instrumentation by Melvin V. Koch,Kurt M. VandenBussche,Ray W. Chrisman Pdf

This first comprehensive treatment of the intertwined roles of micro-instrumentation, high throughput experimentation and process intensification as valuable tools for process analytical technology covers both industrial as well as academic aspects. First class editors and authors from top companies and universities provide interdisciplinary coverage ranging from chemistry and analytics to process design and engineering, supported throughout by case studies and ample analytical data.

Author : W. Jeffrey Hurst
Publisher : CRC Press
Page : 552 pages
File Size : 55,5 Mb
Release : 2008-03-17
Category : Technology & Engineering
ISBN : 1420007157

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Methods of Analysis for Functional Foods and Nutraceuticals, Second Edition by W. Jeffrey Hurst Pdf

In the quest for accurate and efficient analysis of the diverse area encompassed by functional foods and nutraceuticals, analysts encounter unique challenges. Uncertainty over which compound is responsible for a particular health benefit forces analysts to look for marker compounds, sometimes at extremely low levels, and sometimes as part of a matrix possessing its own individual obstacles. Increasing interest from the media, the scientific and nutritional community, and the end consumer, demand a single, comprehensive resource focused on the analysis of this complex category. Methods of Analysis for Functional Foods and Nutraceuticals, Second Edition updates all analytical methods from the first edition to reflect dramatic advances in this field. Providing timely and accurate information with contributions from national and international experts, it presents more than 85 % new or revised information. The addition of three entirely new chapters on the burgeoning field of polyphenol analysis reflects the growing interest in antioxidants by the scientific and lay community. Divided into 10 chapters, this book gathers updated, in-depth treatments of the methods of analysis for phytoestrogens, fatty acids and conjugated linoleic acid, flavonoids, anthocyanins, carotenoids and provitamin A, chlorophylls, water soluble vitamins, amino acids, and carbohydrates. It also includes specialty information such as the use of residues from vineyards and oil production for phenolic compounds. Thoroughly reviewed by a leading panel of scientific peers, the second edition of this highly successful volume is an invaluable source of information for laboratories involved in the food, dietary supplement, and pharmaceutical industry.

Author : Alberto Escarpa,María Cristina González,Miguel Ángel López
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 47,7 Mb
Release : 2015-07-15
Category : Science
ISBN : 9781118682968

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Agricultural and Food Electroanalysis by Alberto Escarpa,María Cristina González,Miguel Ángel López Pdf

Agricultural and Food Electroanalysis offers a comprehensive rationale of electroanalysis, revealing its enormous potential in agricultural food analysis. A unique approach is used which fills a gap in the literature by bringing in applications to everyday problems. This timely text presents in-depth descriptions about different electrochemical techniques following their basic principles, instrumentation and main applications. Such techniques offer invaluable features such as inherent miniaturization, high sensitivity and selectivity, low cost, independence of sample turbidity, high compatibility with modern technologies such as microchips and biosensors, and the use of exciting nanomaterials such as nanoparticles, nanotubes and nanowires. Due to the advantages that modern electroanalytical techniques bring to food analysis, and the huge importance and emphasis given today to food quality and safety, this comprehensive work will be an essential read for professionals and researchers working in analytical laboratories and development departments, and a valuable guide for students studying for careers in food science, technology and chemistry.

Author : P. T. Kissinger
Publisher : Unknown
Page : 128 pages
File Size : 40,8 Mb
Release : 2024-06-18
Category : Electronic
ISBN : 0824700198

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Electrochemical Detection in HPLC and HPCE by P. T. Kissinger Pdf

Author : I.H. Acworth,M. Naoi,Hasan Parvez,S. Parvez
Publisher : CRC Press
Page : 393 pages
File Size : 53,5 Mb
Release : 2024-01-26
Category : Science
ISBN : 9781466563711

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Coulometric Electrode Array Detectors for HPLC by I.H. Acworth,M. Naoi,Hasan Parvez,S. Parvez Pdf

This sixth volume in the book series Progress in HPLC-HPCE examines the enhancement of high- performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) --- the coulometric array detection --- from its initial, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100% efficient and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector.