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Author : P. Gopalakrishnakone,Anita Malhotra
Publisher : Unknown
Page : 128 pages
File Size : 53,7 Mb
Release : 2015
Category : Electronic books
ISBN : 9400767277
Author : Bryan Fry
Publisher : Oxford University Press, USA
Page : 609 pages
File Size : 55,6 Mb
Release : 2015
Category : Medical
ISBN : 9780199309399
"Venomous Reptiles And Their Toxins is a comprehensive study of the entire scope of reptile venom, from its evolution to drug design and development. This book devotes a chapter to each toxin class found in reptile venom, detailing the full trajectory of research on the toxin in question. The comprehensive synthesis of research deals with the impact that venom has had on biomedical applications and snake evolution and ecology"--back cover.
Author : G. Habermehl
Publisher : Springer Science & Business Media
Page : 205 pages
File Size : 51,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642886058
Venomous Animals have been a threat to man at all times, in the warm and wilder regions more than in the temperate areas. People in especially dangerous regions know about these risks and live accordingly. However, with modern tourism and nearly unlimited travel oppor tunities more and more people without experience and knowledge about venomous animals come into contact with them; this book is intended to provide these people with an introduction to the subject. Venomous animals, their habits, their whole ecology and their venoms have been the object or research since the beginning of this century; truly intensive work, how ever, first started about thirty years ago. Medical treat ment therefore has been changed by new insights in the mechanism of action and the constituents of the various venoms. In this regard this book is also directed to physi cians, biologists and chemists to give them an introduc tion in this important and interesting field. New aspects of treatment of envenomations are reported. This book cannot replace bigger textbooks and monographs - they are cited in the references - but it gives an overview and an entry into this field. The original German edition was written at the request of colleagues and students of medicine, biology and chemistry as well as frequent travellers in tropical countries. It was sold out within eight months, thus showing that it really filled a gap.
Author : Wolfgang Bücherl,Eleanor E. Buckley,Venancio Deulofeu
Publisher : Elsevier
Page : 732 pages
File Size : 48,7 Mb
Release : 2013-09-17
Category : Science
ISBN : 9781483263632
Venomous Animals and their Venoms focuses on the comprehensive presentation of the entire field of the venomous members of the animal kingdom, chemistry and biochemistry of venoms, and pharmacological actions and their antigenic properties. The selection first offers information on the development of knowledge about venoms and the platypus (Ornithorhynchus anatinus) and its venomous characteristics, including biology, venom apparatus, properties of venom, and significance of venom apparatus in Ornithorhynchus. The text then elaborates on the classification, biology, and description of the venom apparatus of insectivores of the genera Solenodon, Neomys, and Blarina and the chemistry and pharmacology of insectivore venoms. The publication takes a look at karyotypes, sex chromosomes, and chromosomal evolution in snakes and coagulant, proteolytic, and hemolytic properties of some snake venoms. Topics include hemolytic property, karyotypes of South American snakes, sex chromosomes, methods for the study of chromosomes of reptiles, and chromosomal evolution. The selection is a vital source of data for readers interested in venomous animals and their venoms.
Author : Ronald Jenner,Eivind Undheim
Publisher : Smithsonian Institution
Page : 207 pages
File Size : 44,6 Mb
Release : 2017-10-17
Category : Nature
ISBN : 9781588344540
Venom brings readers face to face with some of the most dangerous creatures on the planet, including jellyfish, snakes, and wasps, as it uncovers the story of venom. The book explores how venom is used for predation, defense, competition, and communication by an incredible diversity of species. It examines the unique methods that these species have evolved to create and deliver their deadly toxins. The book traces venom back to its origin in early jellyfish and sea anemones, and reveals how venoms have evolved dozens of times independently all across the animal kingdom since that time. And finally, it examines the relationships between these dangerous creatures and humans. Humans have not only learned to live with them, but also to benefit from them: scientists increasingly are harnessing the power of venom to create new drugs, treatments, and anti-venoms.
Author : Christie Wilcox
Publisher : Scientific American / Farrar, Straus and Giroux
Page : 256 pages
File Size : 42,7 Mb
Release : 2016-08-09
Category : Science
ISBN : 9780374712211
A thrilling tale of encounters with nature’s masters of biochemistry From the coasts of Indonesia to the rainforests of Peru, venomous animals are everywhere—and often lurking out of sight. Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world. Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out. Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated. Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.
Author : Sebastien Dutertre,Maria Vittoria Modica,Mande Holford,Kartik Sunagar
Publisher : Frontiers Media SA
Page : 127 pages
File Size : 48,6 Mb
Release : 2020-05-06
Category : Electronic
ISBN : 9782889637126
Author : Bruce W. Halstead
Publisher : Darwin Press, Incorporated
Page : 1512 pages
File Size : 50,6 Mb
Release : 1988
Category : Medical
ISBN : MINN:31951000460585V
A complete survey of a broad field of science dating back to the dawn of history is rarely attempted in the day, but the present work is an example of such a study. The scope of this work is truly comprehensive, and an effort has been made to include references to all published work which has appeared since antiquity. Persons carrying out research on these animals and their toxins know well the difficulties of surveying the literature, difficulties due in part to the appearance of much important information in sources other than research publications. There are a host of poisonous and venomous animals known to be capable of inflicting severe injuries in man, and yet chemical and pharmacological studies are nonexistent. Possible roles of most of these toxins in the ecology of the animals have not been investigated in spite of the obvious importance of this aspect. This is a definitive work in an important but neglected area of biology, and this treatise will be a major reference source for decades.
Author : Gandhi Radis-Baptista
Publisher : BoD – Books on Demand
Page : 548 pages
File Size : 55,8 Mb
Release : 2013-07-01
Category : Medical
ISBN : 9789535111511
Molecular Toxinology has been consolidated as a scientific area focused on the intertwined description of several aspects of animal toxins. In an inquiring biotechnological world, animal toxins appear as an invaluable source for the discovery of therapeutic polypeptides. Animal toxins rely on specific chemical interactions with their partner molecule to exert their biological actions. The comprehension of how molecules interact and recognize their target is essential for the rational exploration of bioactive polypeptides as therapeutics. Investigation on the mechanism of molecular interaction and recognition offers a window of opportunity for the pharmaceutical industry and clinical medicine. Thus, this book brings examples of two interconnected themes - molecular recognition and toxinology concerning to the integration between analytical procedures and biomedical applications.
Author : A. Calmette
Publisher : DigiCat
Page : 284 pages
File Size : 52,8 Mb
Release : 2022-09-15
Category : Fiction
ISBN : EAN:8596547307662
Venoms by A. Calmette is a spectacular textbook on the variety of deadly, venomous creatures whose venom may be counteracted with certain medicines. Contents: "PART II. Secretion and collection of venom in snakes, Chemical study of snake venoms, Physiological action of snake-venoms, Physiology of poisoning in man and animals bitten by the different species of poisonous snakes (Colubridæ, Viperidæ, Hydrophiidæ), Physiology of experimental poisoning, Determination of the lethal doses of venom for different species of animals..."
Author : Steve Backshall
Publisher : Johns Hopkins University Press
Page : 0 pages
File Size : 53,5 Mb
Release : 2008-02-25
Category : Science
ISBN : 0801888336
Venomous creatures such as snakes and spiders are the stuff of human nightmares. Yet toxins are a regular part of the animal world, an essential tool for hunting and defense. A surprising variety of insects, reptiles, and amphibians use venom in their daily lives, either to subdue their prey or to prevent falling victim to another predator. Precisely how many forms of wildlife are venomous is only now becoming clear. From the mighty King Cobra, which can reach over five meters in length, down to the diminutive but lethal Black Widow Spider, natural history expert Steve Backshall takes a fascinating look at more than 60 of the most venomous creatures across the world’s continents. Exciting accounts of Backshall’s personal encounters with some of nature's most dangerous animals help bring to life the world of natural venoms. He explains how different types of toxins work and highlights how some are used in medicine, including in the treatment of chronic disease in humans. A final chapter looks at the future for venomous wildlife and at why conservation measures are urgently required to ensure its continued survival. The first book of its kind on this fascinating subject, Venomous Animals of the World is illustrated throughout with stunning color photographs.
Author : Glenn F. King
Publisher : Royal Society of Chemistry
Page : 320 pages
File Size : 41,7 Mb
Release : 2015-01-27
Category : Science
ISBN : 9781782624370
The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.
Author : P. Gopalakrishnakone,Gerardo A. Corzo,Elia Diego-Garcia,Maria Elena Lima
Publisher : Springer
Page : 0 pages
File Size : 53,7 Mb
Release : 2016-05-10
Category : Medical
ISBN : 9400763883
In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
Author : Katsuhiro Konno,Gandhi Rádis-Baptista
Publisher : MDPI
Page : 404 pages
File Size : 52,5 Mb
Release : 2020-03-25
Category : Medical
ISBN : 9783039285402
Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC–MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.
Author : D. Mebs
Publisher : Unknown
Page : 358 pages
File Size : 53,7 Mb
Release : 2002
Category : Poisonous animals
ISBN : UCSD:31822033152141
Life is a struggle on both land and in the sea and many animals have developed chemical weapons, for attack or defence. These toxins, venoms or poisons, are diverse in both structure and function and are delivered to victims in equally diverse ways. Humans frequently encounter these venomous and poisonous animals and all too often suffer unpleasant consequences including death, be it from a bite or sting causing envenoming, or poisoning after eating the wrong animal. The author, toxicologist at the Department of Forensic Science of the University of Frankfurt, Germany, provides expert information for biologists, toxicologists, pharmacists, physicians, but also for travelers.
