Fault Tolerant Digital Microfluidic Biochips

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Fault-Tolerant Digital Microfluidic Biochips

Paul Pop,Mirela Alistar,Elena Stuart,Jan Madsen
Fault Tolerant Digital Microfluidic Biochips Book PDF

Author : Paul Pop,Mirela Alistar,Elena Stuart,Jan Madsen
Publisher : Springer
Page : 234 pages
File Size : 47,6 Mb
Release : 2015-09-07
Category : Technology & Engineering
ISBN : 9783319230726

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Fault-Tolerant Digital Microfluidic Biochips by Paul Pop,Mirela Alistar,Elena Stuart,Jan Madsen Pdf

This book describes for researchers in the fields of compiler technology, design and test, and electronic design automation the new area of digital microfluidic biochips (DMBs), and thus offers a new application area for their methods. The authors present a routing-based model of operation execution, along with several associated compilation approaches, which progressively relax the assumption that operations execute inside fixed rectangular modules. Since operations can experience transient faults during the execution of a bioassay, the authors show how to use both offline (design time) and online (runtime) recovery strategies. The book also presents methods for the synthesis of fault-tolerant application-specific DMB architectures. · Presents the current models used for the research on compilation and synthesis techniques of DMBs in a tutorial fashion; · Includes a set of “benchmarks”, which are presented in great detail and includes the source code of most of the techniques presented, including solutions to the basic compilation and synthesis problems; · Discusses several new research problems in detail, using numerous examples.

Digital Microfluidic Biochips

Krishnendu Chakrabarty,Fei Su
Digital Microfluidic Biochips Book PDF

Author : Krishnendu Chakrabarty,Fei Su
Publisher : CRC Press
Page : 216 pages
File Size : 54,5 Mb
Release : 2018-10-03
Category : Technology & Engineering
ISBN : 9781351837538

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Digital Microfluidic Biochips by Krishnendu Chakrabarty,Fei Su Pdf

Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip

Sudip Poddar,Bhargab B. Bhattacharya
Error Tolerant Biochemical Sample Preparation with Microfluidic Lab on Chip Book PDF

Author : Sudip Poddar,Bhargab B. Bhattacharya
Publisher : CRC Press
Page : 240 pages
File Size : 46,5 Mb
Release : 2022-07-27
Category : Technology & Engineering
ISBN : 9781000612738

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Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip by Sudip Poddar,Bhargab B. Bhattacharya Pdf

Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.

Secure and Trustworthy Cyberphysical Microfluidic Biochips

Jack Tang,Mohamed Ibrahim,Krishnendu Chakrabarty,Ramesh Karri
Secure and Trustworthy Cyberphysical Microfluidic Biochips Book PDF

Author : Jack Tang,Mohamed Ibrahim,Krishnendu Chakrabarty,Ramesh Karri
Publisher : Springer
Page : 144 pages
File Size : 45,9 Mb
Release : 2019-05-28
Category : Technology & Engineering
ISBN : 9783030181635

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Secure and Trustworthy Cyberphysical Microfluidic Biochips by Jack Tang,Mohamed Ibrahim,Krishnendu Chakrabarty,Ramesh Karri Pdf

This book describes novel hardware security and microfluidic biochip design methodologies to protect against tampering attacks in cyberphysical microfluidic biochips (CPMBs). It also provides a general overview of this nascent area of research, which will prove to be a vital resource for practitioners in the field.This book shows how hardware-based countermeasures and design innovations can be a simple and effective last line of defense, demonstrating that it is no longer justifiable to ignore security and trust in the design phase of biochips.

Cyber Physical Systems

Anupam Baliyan,Kuldeep Singh Kaswan,Naresh Kumar,Kamal Upreti,Ramani Kannan
Cyber Physical Systems Book PDF

Author : Anupam Baliyan,Kuldeep Singh Kaswan,Naresh Kumar,Kamal Upreti,Ramani Kannan
Publisher : CRC Press
Page : 191 pages
File Size : 47,7 Mb
Release : 2023-01-11
Category : Computers
ISBN : 9781000840230

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Cyber Physical Systems by Anupam Baliyan,Kuldeep Singh Kaswan,Naresh Kumar,Kamal Upreti,Ramani Kannan Pdf

Cyber Physical System (CPS) is an integration of computation, networking, and physical processes: the combination of several systems ofdifferent nature whose main purpose is tocontrol a physical process and, through feedback, adapt itself to new conditions, in real time.Cyber Physical System: Concepts and Applications includes an in-depth coverage of the latestmodels and theories that unify perspectives. It expresses the interacting dynamics of the computational and physical components of asystem in a dynamic environment. Covers automatic application of software countermeasures against physical attacks and impact of cyber physical system on industry 4.0 Explains how formal models provide mathematical abstractions to manage the complexity of a system design Offers a rigorous and comprehensive introduction to the principles of design,specification, modelling, and analysis of cyber physicalsystems Discusses the multiple domains where Cyber Physical system has a vital impact and provides knowledge about different models thatprovide mathematical abstractions tomanage the complexity of a system design Provides the rapidly expanding field of cyber-physical systems with a Long-needed foundational text by an established authority This book is primarily aimed at advanced undergraduates, graduates of computer science. Engineers will also find this book useful.

Advances in VLSI and Embedded Systems

Anand D. Darji,Deepak Joshi,Amit Joshi,Ray Sheriff
Advances in VLSI and Embedded Systems Book PDF

Author : Anand D. Darji,Deepak Joshi,Amit Joshi,Ray Sheriff
Publisher : Springer Nature
Page : 293 pages
File Size : 47,8 Mb
Release : 2022-11-30
Category : Technology & Engineering
ISBN : 9789811967801

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Advances in VLSI and Embedded Systems by Anand D. Darji,Deepak Joshi,Amit Joshi,Ray Sheriff Pdf

This book presents select peer-reviewed proceedings of the 2nd International Conference on Advances in VLSI and Embedded Systems (AVES 2021). This book covers cutting-edge original research in VLSI design, devices and emerging technologies, embedded systems, and CAD for VLSI. To address the demand for complex and high-functionality systems as well as portable consumer electronics, the contents focus on advanced topics of circuit and systems design, fabrication, testing, and standardization. This book is useful for students, researchers as well as industry professionals interested in emerging trends in VLSI and embedded systems.

Design and Testing of Digital Microfluidic Biochips

Yang Zhao,Krishnendu Chakrabarty
Design and Testing of Digital Microfluidic Biochips Book PDF

Author : Yang Zhao,Krishnendu Chakrabarty
Publisher : Springer Science & Business Media
Page : 207 pages
File Size : 49,7 Mb
Release : 2012-07-25
Category : Technology & Engineering
ISBN : 9781461403708

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Design and Testing of Digital Microfluidic Biochips by Yang Zhao,Krishnendu Chakrabarty Pdf

This book provides a comprehensive methodology for automated design, test and diagnosis, and use of robust, low-cost, and manufacturable digital microfluidic systems. It focuses on the development of a comprehensive CAD optimization framework for digital microfluidic biochips that unifies different design problems. With the increase in system complexity and integration levels, biochip designers can utilize the design methods described in this book to evaluate different design alternatives, and carry out design-space exploration to obtain the best design point.

Formal Modeling and Verification of Cyber-Physical Systems

Rolf Drechsler,Ulrich Kühne
Formal Modeling and Verification of Cyber Physical Systems Book PDF

Author : Rolf Drechsler,Ulrich Kühne
Publisher : Springer
Page : 313 pages
File Size : 49,7 Mb
Release : 2015-06-05
Category : Computers
ISBN : 9783658099947

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Formal Modeling and Verification of Cyber-Physical Systems by Rolf Drechsler,Ulrich Kühne Pdf

This book presents the lecture notes of the 1st Summer School on Methods and Tools for the Design of Digital Systems, 2015, held in Bremen, Germany. The topic of the summer school was devoted to modeling and verification of cyber-physical systems. This covers several aspects of the field, including hybrid systems and model checking, as well as applications in robotics and aerospace systems. The main chapters have been written by leading scientists, who present their field of research, each providing references to introductory material as well as latest scientific advances and future research directions. This is complemented by short papers submitted by the participating PhD students.

Exact Design of Digital Microfluidic Biochips

Oliver Keszocze,Robert Wille,Rolf Drechsler
Exact Design of Digital Microfluidic Biochips Book PDF

Author : Oliver Keszocze,Robert Wille,Rolf Drechsler
Publisher : Springer
Page : 134 pages
File Size : 40,6 Mb
Release : 2018-06-11
Category : Technology & Engineering
ISBN : 9783319909363

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Exact Design of Digital Microfluidic Biochips by Oliver Keszocze,Robert Wille,Rolf Drechsler Pdf

This book presents exact, that is minimal, solutions to individual steps in the design process for Digital Microfluidic Biochips (DMFBs), as well as a one-pass approach that combines all these steps in a single process. All of the approaches discussed are based on a formal model that can easily be extended to cope with further design problems. In addition to the exact methods, heuristic approaches are provided and the complexity classes of various design problems are determined. Presents exact methods to tackle a variety of design problems for Digital Microfluidic Biochips (DMFBs); Describes an holistic, one-pass approach solving different design steps all at once; Based on a formal model of DMFBs that is easily adaptable to deal with further design tasks.

Design Automation Methods and Tools for Microfluidics-Based Biochips

Jun Zeng
Design Automation Methods and Tools for Microfluidics Based Biochips Book PDF

Author : Jun Zeng
Publisher : Springer Science & Business Media
Page : 407 pages
File Size : 41,9 Mb
Release : 2006-11-08
Category : Technology & Engineering
ISBN : 9781402051234

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Design Automation Methods and Tools for Microfluidics-Based Biochips by Jun Zeng Pdf

Design Automation Methods and Tools for Microfluidics-Based Biochips deals with all aspects of design automation for microfluidics-based biochips. Experts have contributed chapters on many aspects of biochip design automation. Topics covered include: device modeling; adaptation of bioassays for on-chip implementations; numerical methods and simulation tools; architectural synthesis, scheduling and binding of assay operations; physical design and module placement; fault modeling and testing; and reconfiguration methods.

Digital Microfluidic Biochips

Krishnendu Chakrabarty,Tao Xu
Digital Microfluidic Biochips Book PDF

Author : Krishnendu Chakrabarty,Tao Xu
Publisher : CRC Press
Page : 377 pages
File Size : 42,7 Mb
Release : 2010-05-03
Category : Medical
ISBN : 9781439858738

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Digital Microfluidic Biochips by Krishnendu Chakrabarty,Tao Xu Pdf

Microfluidics-based biochips combine electronics with biochemistry, providing access to new application areas in a wide variety of fields. Continued technological innovations are essential to assuring the future role of these chips in functional diversification in biotech, pharmaceuticals, and other industries.Revolutionary guidance on design, opti

Micro-Electrode-Dot-Array Digital Microfluidic Biochips

Zipeng Li,Krishnendu Chakrabarty,Tsung-Yi Ho,Chen-Yi Lee
Micro Electrode Dot Array Digital Microfluidic Biochips Book PDF

Author : Zipeng Li,Krishnendu Chakrabarty,Tsung-Yi Ho,Chen-Yi Lee
Publisher : Springer
Page : 144 pages
File Size : 54,7 Mb
Release : 2018-12-14
Category : Technology & Engineering
ISBN : 9783030029647

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Micro-Electrode-Dot-Array Digital Microfluidic Biochips by Zipeng Li,Krishnendu Chakrabarty,Tsung-Yi Ho,Chen-Yi Lee Pdf

This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.

Proceedings of the 10th Ph.D. Retreat of the HPI Research School on Service-oriented Systems Engineering

Meinel, Christoph , Plattner, Hasso , Döllner, Jürgen , Weske, Mathias , Polze, Andreas , Hirschfeld, Robert , Naumann, Felix , Giese, Holger , Baudisch, Patrick , Friedrich, Tobias , Müller, Emmanuel
Proceedings of the 10th Ph D Retreat of the HPI Research School on Service oriented Systems Engineering Book PDF

Author : Meinel, Christoph , Plattner, Hasso , Döllner, Jürgen , Weske, Mathias , Polze, Andreas , Hirschfeld, Robert , Naumann, Felix , Giese, Holger , Baudisch, Patrick , Friedrich, Tobias , Müller, Emmanuel
Publisher : Universitätsverlag Potsdam
Page : 268 pages
File Size : 52,7 Mb
Release : 2018-01-17
Category : Computers
ISBN : 9783869563909

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Proceedings of the 10th Ph.D. Retreat of the HPI Research School on Service-oriented Systems Engineering by Meinel, Christoph , Plattner, Hasso , Döllner, Jürgen , Weske, Mathias , Polze, Andreas , Hirschfeld, Robert , Naumann, Felix , Giese, Holger , Baudisch, Patrick , Friedrich, Tobias , Müller, Emmanuel Pdf

Design and Implementation of service-oriented architectures imposes a huge number of research questions from the fields of software engineering, system analysis and modeling, adaptability, and application integration. Component orientation and web services are two approaches for design and realization of complex web-based system. Both approaches allow for dynamic application adaptation as well as integration of enterprise application. Commonly used technologies, such as J2EE and .NET, form de facto standards for the realization of complex distributed systems. Evolution of component systems has lead to web services and service-based architectures. This has been manifested in a multitude of industry standards and initiatives such as XML, WSDL UDDI, SOAP, etc. All these achievements lead to a new and promising paradigm in IT systems engineering which proposes to design complex software solutions as collaboration of contractually defined software services. Service-Oriented Systems Engineering represents a symbiosis of best practices in object-orientation, component-based development, distributed computing, and business process management. It provides integration of business and IT concerns. The annual Ph.D. Retreat of the Research School provides each member the opportunity to present his/her current state of their research and to give an outline of a prospective Ph.D. thesis. Due to the interdisciplinary structure of the research school, this technical report covers a wide range of topics. These include but are not limited to: Human Computer Interaction and Computer Vision as Service; Service-oriented Geovisualization Systems; Algorithm Engineering for Service-oriented Systems; Modeling and Verification of Self-adaptive Service-oriented Systems; Tools and Methods for Software Engineering in Service-oriented Systems; Security Engineering of Service-based IT Systems; Service-oriented Information Systems; Evolutionary Transition of Enterprise Applications to Service Orientation; Operating System Abstractions for Service-oriented Computing; and Services Specification, Composition, and Enactment.

VLSI 2010 Annual Symposium

Nikolaos Voros,Amar Mukherjee,Nicolas Sklavos,Konstantinos Masselos,Michael Huebner
VLSI 2010 Annual Symposium Book PDF

Author : Nikolaos Voros,Amar Mukherjee,Nicolas Sklavos,Konstantinos Masselos,Michael Huebner
Publisher : Springer Science & Business Media
Page : 341 pages
File Size : 45,6 Mb
Release : 2011-09-08
Category : Technology & Engineering
ISBN : 9789400714885

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VLSI 2010 Annual Symposium by Nikolaos Voros,Amar Mukherjee,Nicolas Sklavos,Konstantinos Masselos,Michael Huebner Pdf

VLSI 2010 Annual Symposium will present extended versions of the best papers presented in ISVLSI 2010 conference. The areas covered by the papers will include among others: Emerging Trends in VLSI, Nanoelectronics, Molecular, Biological and Quantum Computing. MEMS, VLSI Circuits and Systems, Field-programmable and Reconfigurable Systems, System Level Design, System-on-a-Chip Design, Application-Specific Low Power, VLSI System Design, System Issues in Complexity, Low Power, Heat Dissipation, Power Awareness in VLSI Design, Test and Verification, Mixed-Signal Design and Analysis, Electrical/Packaging Co-Design, Physical Design, Intellectual property creating and sharing.

VLSI Design and Test

Manoj Singh Gaur,Mark Zwolinski,Vijay Laxmi,D. Boolchandani,Virendra Sing,Adit Singh
VLSI Design and Test Book PDF

Author : Manoj Singh Gaur,Mark Zwolinski,Vijay Laxmi,D. Boolchandani,Virendra Sing,Adit Singh
Publisher : Springer
Page : 403 pages
File Size : 54,7 Mb
Release : 2013-12-13
Category : Computers
ISBN : 9783642420245

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VLSI Design and Test by Manoj Singh Gaur,Mark Zwolinski,Vijay Laxmi,D. Boolchandani,Virendra Sing,Adit Singh Pdf

This book constitutes the refereed proceedings of the 17th International Symposium on VLSI Design and Test, VDAT 2013, held in Jaipur, India, in July 2013. The 44 papers presented were carefully reviewed and selected from 162 submissions. The papers discuss the frontiers of design and test of VLSI components, circuits and systems. They are organized in topical sections on VLSI design, testing and verification, embedded systems, emerging technology.