Frontiers In Brain Repair

Author : Rahul Jandial
Publisher : Springer Science & Business Media
Page : 150 pages
File Size : 46,5 Mb
Release : 2010-12-31
Category : Medical
ISBN : 9781441958198

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Frontiers in Brain Repair by Rahul Jandial Pdf

In the rapidly-evolving landscape of neurosciences, it is no easy task to select a limited array of topics to present in a text such as this. The current volume takes as its purpose to provide a representative survey of the current science of brain repair for those seeking to establish a foundation in the field or to replenish a prior knowledge base that may have lapsed in its currency. It also hopes to offer insights into what remains elusive to our collective investigations, defining the “frontiers” of brain repair for those that are currently immersed in the exciting intersection of biological advances and neuroscientific discoveries. In Chapter 1 the fundamentals of imaging transplanted cells is discussed with emphasis on animal models as well as the horizon for clinical trials. Then, detailed methods on the culture of neural stem cells is reviewed as a foundation for approaching therapeutic goals. Chapter 3 presents the broad scope of animal models that serve as the foundation for developmental and pre-clinical investigation, with mention of recent genetically engineered mouse models that represent the best models for studying disease development and treatment. Chapter 4 provides background on the delivery techniques to animals and patients that are available, providing vital information on the subtleties of technique necessary for optimal cellular grafting. Chapters 5 and 6 discuss new and evolving information on the origins of brain tumors and the indelible role of stromal and microenvironmental influences on oncogenesis and tumor progression. Subsequently, the utility of neural stem cells as cellular vehicles to deliver chemotherapeutics to broad neuropathology is reviewed. In Chapter 8 the scope of treating brain tumors is expanded beyond stem cells, to present the best biological interventions to improve upon current treatment options for brain malignancy. The last two chapters present a comprehensive review on stem cell and gene therapy options for treating cerebrovascular and neurovascular pathology. In amassing this collection, my intention has been to provide the reader with a broad introduction into molecular imaging, stem cell biology, cell therapy, animal models, central nervous system malignancies, stroke, and neurodegeneration. My hope is that Frontiers of Brain Repair will be the intellectual soil from which a deeply rooted and well-nourished vintage of neuroscience will arise.

Author : Donald G. Stein,Simón Brailowsky,Bruno Will
Publisher : Oxford University Press, USA
Page : 190 pages
File Size : 41,8 Mb
Release : 1997
Category : Medical
ISBN : 0195119185

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Brain Repair by Donald G. Stein,Simón Brailowsky,Bruno Will Pdf

Over a half million people each year suffer brain-damaging injuries and diseases--but the outlook for their eventual recovery is far more hopeful than it was just a short while ago. In Brain Repair, three internationally renowned neuroscientists team up to offer an intriguing and up-to-the-minute introduction to the explosive advances being made in the research, technology, and treatment of brain damage. The key to neuroscience's most exciting discoveries to date is a theory that is rapidly gaining adherents in the scientific community--the theory of neuroplasticity. Neuroplasticity stresses that cells throughout the brain can not only regenerate, but can adapt their function to assume critical roles once performed by damaged tissue. In clear, accessible language, the authors show us that the brain manufactures a host of complex chemicals that actually foster growth in damaged brain cells. We visit the laboratories where researchers are untangling the mystery of Parkinson's disease and trying to understand what goes wrong in stroke victims, and why some, thought permanently impaired, show remarkable improvements. In addition, they discuss how even today misguided ideas can adversely affect how physicians treat patients. And, along the way, they detail the fascinating history of how brain structure and functioning has been understood and studied, from prehistoric times to the present. A best-selling volume in France and Mexico, Brain Repair provides a vividly written, wide-ranging look at the leading edge of one of science's most exciting frontiers.

Author : Daniella Rylander Ottosson,Andreas Heuer,Sofia Grade
Publisher : Frontiers Media SA
Page : 140 pages
File Size : 45,7 Mb
Release : 2021-07-15
Category : Science
ISBN : 9782889710454

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Regeneration and Brain Repair by Daniella Rylander Ottosson,Andreas Heuer,Sofia Grade Pdf

Author : Sara Pedron,Brendan A.C. Harley
Publisher : Unknown
Page : 0 pages
File Size : 42,8 Mb
Release : 2019
Category : Electronic
ISBN : OCLC:1368443981

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Biomaterials for Brain Therapy and Repair by Sara Pedron,Brendan A.C. Harley Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 42,8 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : Hiroaki Naritomi,D. W. Krieger
Publisher : Karger Medical and Scientific Publishers
Page : 162 pages
File Size : 41,6 Mb
Release : 2013
Category : Medical
ISBN : 9783318023084

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Clinical Recovery from CNS Damage by Hiroaki Naritomi,D. W. Krieger Pdf

A compilation of innovative findings and new directions in neurological recovery After decades of focusing on how to alleviate and prevent recurrence of acute CNS injuries, the emphasis has finally shifted towards repairing such devastating events and rehabilitation. This development has been made possible by substantial progress in understanding the scientific underpinnings of recovery as well as by novel diagnostic tools, and most importantly, by emerging therapies awaiting clinical trials. In this publication, several international experts introduce novel areas of neurological reorganization and repair following CNS damage. Principles and methods to monitor and augment neuroplasticity are explored in depth and supplemented by a critical appraisal of neurological repair mechanisms and possibilities to curtail disability using computer or robotic interfaces. Rather than providing a textbook approach of CNS restoration, the editors selected topics where progress is most imminent in this labyrinthine domain of medicine. Moreover, the varied background and origins of the contributors lend this book a truly global perspective on the current state of affairs in neurological recovery.

Author : Firas H. Kobeissy
Publisher : CRC Press
Page : 718 pages
File Size : 43,6 Mb
Release : 2015-02-25
Category : Medical
ISBN : 9781466565999

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Brain Neurotrauma by Firas H. Kobeissy Pdf

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Author : Steven C. Cramer,Randolph J. Nudo
Publisher : Cambridge University Press
Page : 307 pages
File Size : 46,9 Mb
Release : 2010-10-28
Category : Medical
ISBN : 9781139490658

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Brain Repair After Stroke by Steven C. Cramer,Randolph J. Nudo Pdf

Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Author : Jacoba M. Spikman,Joukje Van Der Naalt,Dawn Neumann,Maarten Valentijn Milders
Publisher : Unknown
Page : 0 pages
File Size : 40,8 Mb
Release : 2020
Category : Electronic
ISBN : OCLC:1368422647

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Neurobehavioral Changes After Acquired Brain Injury by Jacoba M. Spikman,Joukje Van Der Naalt,Dawn Neumann,Maarten Valentijn Milders Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Norman Doidge
Publisher : Penguin
Page : 448 pages
File Size : 51,9 Mb
Release : 2015-01-27
Category : Medical
ISBN : 9780698191433

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The Brain's Way of Healing by Norman Doidge Pdf

NEW YORK TIMES BESTSELLER The New York Times–bestselling author of The Brain That Changes Itself presents astounding advances in the treatment of brain injury and illness. Now in an updated and expanded paperback edition. Winner of the 2015 Gold Nautilus Book Award in Science & Cosmology In his groundbreaking work The Brain That Changes Itself, Norman Doidge introduced readers to neuroplasticity—the brain’s ability to change its own structure and function in response to activity and mental experience. Now his revolutionary new book shows how the amazing process of neuroplastic healing really works. The Brain’s Way of Healing describes natural, noninvasive avenues into the brain provided by the energy around us—in light, sound, vibration, and movement—that can awaken the brain’s own healing capacities without producing unpleasant side effects. Doidge explores cases where patients alleviated chronic pain; recovered from debilitating strokes, brain injuries, and learning disorders; overcame attention deficit and learning disorders; and found relief from symptoms of autism, multiple sclerosis, Parkinson’s disease, and cerebral palsy. And we learn how to vastly reduce the risk of dementia, with simple approaches anyone can use. For centuries it was believed that the brain’s complexity prevented recovery from damage or disease. The Brain’s Way of Healing shows that this very sophistication is the source of a unique kind of healing. As he did so lucidly in The Brain That Changes Itself, Doidge uses stories to present cutting-edge science with practical real-world applications, and principles that everyone can apply to improve their brain’s performance and health.

Author : William M. Reichert
Publisher : CRC Press
Page : 300 pages
File Size : 42,6 Mb
Release : 2007-12-17
Category : Medical
ISBN : 9781420009309

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Indwelling Neural Implants by William M. Reichert Pdf

Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel

Author : Feng Kong,Aaron Shain Heller,Carien M. van Reekum,Wataru Sato
Publisher : Frontiers Media SA
Page : 188 pages
File Size : 47,6 Mb
Release : 2020-04-13
Category : Electronic
ISBN : 9782889636426

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Positive Neuroscience: the Neuroscience of Human Flourishing by Feng Kong,Aaron Shain Heller,Carien M. van Reekum,Wataru Sato Pdf

Author : Barbara P. Uzzell,Henry H. Stonnington
Publisher : Psychology Press
Page : 372 pages
File Size : 55,9 Mb
Release : 1996
Category : Medical
ISBN : 0805818243

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Recovery After Traumatic Brain Injury by Barbara P. Uzzell,Henry H. Stonnington Pdf

First Published in 1996. Routledge is an imprint of Taylor & Francis, an informa company.

Author : M.A. Steiner,M. Yanagisawa,M. Clozel
Publisher : Karger Medical and Scientific Publishers
Page : 165 pages
File Size : 53,8 Mb
Release : 2021-05-28
Category : Health & Fitness
ISBN : 9783318068443

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The Orexin System. Basic Science and Role in Sleep Pathology by M.A. Steiner,M. Yanagisawa,M. Clozel Pdf

The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

Author : Dan Engle
Publisher : Unknown
Page : 0 pages
File Size : 43,8 Mb
Release : 2017-10-17
Category : Brain
ISBN : 1946697346

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The Concussion Repair Manual by Dan Engle Pdf

The Concussion Repair Manual is a user's guide for those suffering after head traumas and those that support them. It is one-part "textbook," packed with the leading research on medical technologies for healing the injured brain, and one-part "workbook," offering a step-by-step method for making and tracking a personalized recovery regimen.