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Functional Metagenomics: Tools and Applications by Trevor C. Charles,Mark R. Liles,Angela Sessitsch Pdf
In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.
Functional Metagenomics: Microbial Diversity, Interaction, and Application in Bioremediation uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices.Content further explains the newly developed techniques for sequencing DNA; generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time. The content finally explores the role of metagenomics in studying microbial diversity, interaction and application in bioremediation studies and gives the reader overall detailed information regarding metagenomics, its application as well as techniques. Provides comprehensive information to readers on state-of-the-art applications in metagenomics Summarizes our current knowledge of the use of metagenomics and gives a novel and powerful insight into the already existing bioremediation process Gives an overall picture of metagenomics, its application, processes, and future prospects in the field of bioremediation
Metagenomics: Techniques, Applications, Challenges and Opportunities by Reena Singh Chopra,Chirag Chopra,Neeta Raj Sharma Pdf
This book summarizes the various areas of research in metagenomics and their potential applications in medicine, the environment and biotechnology. The book presents the recent advances in theoretical, methodological and applied aspects of metagenomics and highlights their applications in the fields of environmental microbial forensics, bioremediation, drug-discovery and agriculture. In addition, the book discusses various metagenomics approaches used for understanding the microbial physiology and biochemistry. Lastly the book describes a range of bioinformatics tools and computational methods for metagenomics analysis as well as the functional diversity and dynamics of microbial communities colonizing the human skin.
National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Metagenomics: Challenges and Functional Applications
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Metagenomics: Challenges and Functional Applications Publisher : National Academies Press Page : 170 pages File Size : 45,7 Mb Release : 2007-06-24 Category : Science ISBN : 9780309106764
The New Science of Metagenomics by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Metagenomics: Challenges and Functional Applications Pdf
Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.
Modern Soil Microbiology, Third Edition by Jan Dirk van Elsas,Jack T. Trevors,Alexandre Soares Rosado,Paolo Nannipieri Pdf
The living soil is crucial to photosynthesis, biogeochemical cycles, global food production, climate change, biodiversity, and plant and animal health. In the past decade, scientists have made significant advances in soil microbiology research. While the basic principles are now better understood, knowledge has been forthcoming on the best available technologies and methods applied to researching soil microorganisms, their diversity, interactions, biochemistry, survival, gene expression, and their roles in global climate change, plant disease suppression and growth stimulation, and biogeochemical cycles. This knowledge can be applied to better predict the transformation of pollutants in soil and the activities of microbes in the rhizosphere. It will also assist us in fostering crop production in an era with an increasing human population and intensification of agriculture. Following the tradition of its predecessors, Modern Soil Microbiology, Third Edition, is an indispensable source that supports graduate/undergraduate teaching for soil and environmental microbiologists in academia, as well as in government and industrial laboratories. It is a comprehensive collection of chapters on various aspects of soil microbiology, useful for all professionals working with soils. Compiled by internationally renowned educators and research scholars, this textbook contains key tables, figures, and photographs, supported by thousands of references to illustrate the depth of knowledge in soil microbiology. FEATURES Fully updated and expanded to include new key chapters on historical developments, future applications, and soil viruses and proteins Discusses molecular methods applied to soil microbiology, diverse soil microorganisms, and global climate change Emphasizes the role of terrestrial microorganisms and cycles involved in climate change Details the latest molecular methods applied to soil microbiology research User-friendly for students, and containing numerous tables, figures, and illustrations to better understand the current knowledge in soil microbiology
Metagenomics: Perspectives, Methods, and Applications provides thorough coverage of the growing field of metagenomics. A diverse range of chapters from international experts offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments. The emphasis on application makes this text particularly useful for applied researchers, practitioners, clinicians and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case-study based application chapters examine topics ranging from viral metagenome profiling, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. Additionally, perspectives on future potential at the end of each chapter provoke new thought and motivations for continued study in this exciting and fruitful research area. Provides thorough coverage of the rapidly growing field of metagenomics, with an emphasis on applications of relevance to translational researchers, practitioners, clinicians and students Features a diverse range of chapters from international experts that offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools and research pipelines Highlights perspectives on future potential at the end of each chapter to provoke new thought and motivations for continued study in this exciting and fruitful research area
Metagenomics and Microbial Ecology by Surajit De Mandal,Amrita Kumari Panda,N. Senthil Kumar,Satpal Singh Bisht,Fengliang Jin Pdf
Microorganisms comprise the greatest genetic diversity in the natural ecosystem, and characterization of these microbes is an essential step towards discovering novel products or understanding complex biological mechanisms. The advancement of metagenomics coupled with the introduction of high-throughput, cost-effective NGS technology has expanded the possibilities of microbial research in various biological systems. In addition to traditional culture and biochemical characteristics, omics approaches (metagenomics, metaproteomics, and metatranscriptomics) are useful for analyzing complete microbial communities and their functional attributes in various environments. Metagenomics and Microbial Ecology: Techniques and Applications explores the most recent advances in metagenomics research in the landscape of next-generation sequencing technologies. This book also describes how advances in sequencing technologies are used to study invisible microbes as well as the relationships between microorganisms in their respective environments. Features: Covers a wide range of concepts, investigations, and technological advancement in metagenomics at the global level. Highlights the novel and recent approaches to analyze microbial diversity and its functional attributes. Features a range of chapters that present an introduction to the field and functional insight into various ecosystems.
Genomics Approach to Bioremediation by Vineet Kumar,Muhammad Bilal,Luiz Fernando Romanholo Ferreira,Hafiz M. N. Iqbal Pdf
Genomics Approach to Bioremediation Provides insights into the various aspects of microbial genomics and biotechnology for environmental cleanup In recent years, the application of genomics to biodegradation and bioremediation research has led to a better understanding of the metabolic capabilities of microorganisms, their interactions with hazardous and toxic chemical compounds, and their adaptability to changing environmental conditions. Genomics Approach to Bioremediation: Principles, Tools, and Emerging Technologies provides comprehensive and up-to-date information on cutting-edge technologies and approaches in bioremediation and biodegradation of environmental pollutants. Edited by prominent researchers in the field, this authoritative reference examines advanced genomics technologies, next-generation sequencing (NGS), and state-of-the-art bioinformatics tools while offering valuable insights into the unique functional attributes of different microbial communities and their impact on the removal of chemical contaminants. Each chapter includes numerous high-quality illustrations, detailed tables, extensive references, and step-by-step descriptions of various microbial metabolic pathways of degradation and biotransformation of environments containing various inorganic, metallic, organometallic, and organic hydrocarbon contaminants. • Describes methodologies and underlying theory for the remediation, detoxification, and degradation of contaminated environments • Covers new genomics technologies that address nutrient removal, resource recovery, and other major trends in environmental cleanup • Highlights recent advances in microbial biotechnological approaches including the latest description of the relationship between microbes and the environment focusing on their impact on ecosystem services. • Offers perspectives on energy saving, production, sustainability, and community involvement • Discusses current challenges and future directions in the field of bioremediation Genomics Approach to Bioremediation: Principles, Tools, and Emerging Technologies is an essential resource for biochemical and environmental engineers, environmental microbiologists, academic researchers, process and treatment plant managers, policymakers, and industry professionals working in the areas of microbial degradation, bioremediation, and phytoremediation.
Metagenomics by Wolfgang R. Streit,Rolf Daniel Pdf
This volume provides up-to-date and novel techniques for various screening technologies currently used in metagenomics and related areas. Starting with DNA/RNA isolation from environmental samples, the book continues by delving into areas such as current methods used to isolate DNA and construct metagenomic libraries, establishment of metagenome libraries in non-E. coli hosts, and topics like function-driven mining of metagenomic DNA, screening and analyzing protocols for a wide array of different genes encoding enzymes, bacterial viruses and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Metagenomics: Methods and Protocols, Third Edition provides a comprehensive collection of up-to-date metagenome protocols and tools for the recovery of many major types of biocatalysts and allows for the easy setup of these screens in microbiology laboratories.
Omics Insights in Environmental Bioremediation by Vineet Kumar,Indu Shekhar Thakur Pdf
Environmental pollution emanating from rapid industrialization, population growth, and urbanization has been considered a major problem in recent years that affects biodiversity, ecosystems, and human health by contaminating soil and water. This book brings out a comprehensive collection of information on valuable insights into different cutting-edge omics technologies, such as metagenomics, metatranscriptomics, metaproteomics, and metabolomics, along with advanced next-generation sequencing technologies as well as bioinformatic tools, which led to a better understanding of microbial communities and their adaptability to a wide range of contaminants and underlying their mechanisms in bioremediation and biodegradation of environmental pollutants. In addition, this edited volume provides critical insight into of potent microbial communities endowed with unique functional attributes through their unique metabolism catalyzed by ‘signature’ enzymes and degradation pathways. Step-by-step descriptions are provided of various microbial metabolic pathways of degradation and biotransformation of environmental contaminants by numerous illustrations which make the information easier to understand for the readers. Each chapter is devoted to selected examples of microbial bioremediation supported by tables, and an extensive list of references for readers interested in learning further details about the subject matter. This book is of interest to teachers, researchers to professionals, policymakers, stockholders, practitioners, environmental engineers, soil scientists, and policymakers. In addition, the book serves as additional comprehensive material for undergraduate, graduate, and doctoral students who require a working knowledge and knowhow of ‘Omics’ involved in and required for environmental remediation of legacy and emerging contaminants, will also find this to be a useful read.
Bioremediation: Challenges and Advancements by Manikant Tripathi,Durgesh Narain Singh Pdf
Waste management is one of the major challenges for environmental and public health organizations for maintaining safety standards in any area. Population growth and urbanization increase the difficulty in maintaining a sustainable waste management system. Bioremediation refers to the use of living organisms in processes designed to remove toxic chemicals present in waste material. Bioremediation represents a sustainable way to remove a range of environmental pollutants. Bioremediation: Challenges and Advancements covers the subject of bioremediation in eight chapters that focus on a broad range of waste sources, their adverse impacts on the ecosystem, and the advanced strategies for their remediation. Each chapter also highlights the problems encountered in bioremediation processes. Key features: - Comprehensive coverage of bioremediation in 8 reader-friendly chapters - Highlights methods and challenges of bioremediation in one volume. - Introduces the reader to bioremediation - Explains recent biotechnological methods for removing heavy metals and xenobiotic compounds - Describes strategies including physical, chemical, and biological methods to mitigate radioactive waste from contaminated sites and water bodies - Details the use of microbial-aided remediation techniques for the management of biomedical and electronic wastes, and its impact on the ecosystem - Describes bioremediation technologies for decontamination of solid waste pollutants - Showcases the application of Omics approaches such as genomics, transcriptomics, proteomics, and metabolomics to improve bioremediation processes. - Covers bioremediation of agro-wastes - Includes detailed references This book is an informative reference for scholars (researchers, undergraduate and graduate students of environmental sciences, microbiology and biotechnology) professionals (environmental engineers) and researchers, giving each a good understanding of the significance of bioremediation in solid waste management and the restoration of contaminated sites.
Biosurfactants: A Boon to Healthcare, Agriculture & Environmental Sustainability by Arun Kumar Pradhan, Manoranjan Arakha Pdf
Biosurfactants, derived from microbes and plants, exhibit diverse properties that help in emulsifying and foaming processes. With applications in pharmaceuticals, cosmetics, and agriculture, they also show antimicrobial and environmental benefits, such as oil removal in polluted areas. Biosurfactants show promise for pollution control and improving agriculture. This reference covers the basic science and major applications of biosurfactants. The book brings together contributions from experts in microbiology, cancer biology, pharmaceutical science, nanotechnology, plant biotechnology and environmental sciences into a single volume. The key features of the book are - Explains the basics of biosurfactants - Discusses novel applications of biosurfactants in the field of medicine, agriculture and environmental sustainability. - Includes special chapters that review the role of biosurfactants in environmental remediation and omics research - Includes detailed references in each chapter This book is an essential resource for learners and professional trainees who require knowledge about biosurfactants. It also provides information for anyone who is working on environmental sustainability projects.
Advances in Bioinformatics by Vijai Singh,Ajay Kumar Pdf
This book presents the latest developments in bioinformatics, highlighting the importance of bioinformatics in genomics, transcriptomics, metabolism and cheminformatics analysis, as well as in drug discovery and development. It covers tools, data mining and analysis, protein analysis, computational vaccine, and drug design. Covering cheminformatics, computational evolutionary biology and the role of next-generation sequencing and neural network analysis, it also discusses the use of bioinformatics tools in the development of precision medicine. This book offers a valuable source of information for not only beginners in bioinformatics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in many areas.
Multifunctional Microbial Biosurfactants by Pankaj Kumar,Ramesh Chandra Dubey Pdf
This book provides an overview of biosurfactants as biobased compounds, and highlights novel applications in several industries, including biotech, food processing, cosmetic, oil recovery/petroleum, pharmaceutical, detergent and textile. In the past few decades, biosurfactants have emerged as promising alternative surface-active agents to chemical surfactants due to their high biodegradability, low toxicity, multi-functionality under extreme pH and temperature conditions, long-term physicochemical stability, and their production from renewable sources. This book presents the fundamental aspects (classification, structure, genetics, and properties) of biosurfactants and how their features contribute to the global bioeconomy. Chapters from expert contributors discuss the latest screening, purification and characterization methods of new biosurfactants and biosurfactant-producing fungi and bacteria, including extremophiles. Particular attention is given to the role of biosurfactants in the formulation of sustainable agrochemicals, and their application as eco-friendly mosquitocidal agents, and biopesticides. Readers will discover a perspective on the antiviral activity of biosurfactants, in which the latest in vitro and in silico studies are discussed. Readers will also find more about the foremost therapeutic attributes of biosurfactant-mediated nanoparticles as next-generation drug delivery systems. Given its breadth, this book appeals to a wide readership, from students and academic researchers to scientists and professionals from industry, interested in the study and application of microbial surfactants.