Genome Research

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome
Publisher : National Academies Press
Page : 128 pages
File Size : 54,9 Mb
Release : 1988-01-01
Category : Science
ISBN : 9780309038409

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Mapping and Sequencing the Human Genome by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome Pdf

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Author : Clyde R. Williams
Publisher : Nova Publishers
Page : 442 pages
File Size : 44,8 Mb
Release : 2004
Category : Medical
ISBN : 1590339606

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Focus on Genome Research by Clyde R. Williams Pdf

The genomic approach of technology development and large-scale generation of community resource data sets has introduced an important new dimension in biological and biomedical research. Interwoven advances in genetics, comparative genomics, high throughput biochemistry and bioinformatics are combining to attack basic understanding of human life and disease and to develop strategies to combat disease. Genomic Research began with The Human Genome Project (HGP), the international research effort that determined the DNA sequence of the entire human genome, completed in April 2003. The HGP also included efforts to characterize and sequence the entire genomes of several other organisms, many of which are used extensively in biological research. Identification of the sequence or function of genes in a model organism is an important approach to finding and elucidating the function of human genes. Integral to the HGP are similar efforts to understand the genomes of various organisms commonly used in biomedical research, such as mice, fruit flies and roundworms. Such organisms are called "model organisms," because they can often serve as research models for how the human organism behaves. This new book brings together leading research from throughout the world in this cutting-edge field.

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Human Genome Diversity
Publisher : National Academies Press
Page : 101 pages
File Size : 44,5 Mb
Release : 1998-01-19
Category : Science
ISBN : 9780309184748

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Evaluating Human Genetic Diversity by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Human Genome Diversity Pdf

This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

Author : Alberto P. Bellini
Publisher : Nova Publishers
Page : 278 pages
File Size : 47,9 Mb
Release : 2007
Category : Science
ISBN : 1600218059

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Genome Research Advances by Alberto P. Bellini Pdf

The genomic approach of technology development and large-scale generation of community resource data sets has introduced an important new dimension in biological and biomedical research. Interwoven advances in genetics, comparative genomics, high throughput biochemistry and bioinformatics are combining to attack basic understanding of human life and disease and to develop strategies to combat disease. Genomic research began with The Human Genome Project (HGP), the international research effort that determined the DNA sequence of the entire human genome, completed in April 2003. The HGP also included efforts to characterise and sequence the entire genomes of several other organisms, many of which are used extensively in biological research. Identification of the sequence or function of genes in a model organism is an important approach to finding and elucidating the function of human genes. Integral to the HGP are similar efforts to understand the genomes of various organisms commonly used in biomedical research, such as mice, fruit flies and roundworms. Such organisms are called "model organisms," because they can often serve as research models for how the human organism behaves. This book presents the latest advances in this fast-moving field.

Author : Hillary E. Sussman,Maria Ann Smit
Publisher : CSHL Press
Page : 476 pages
File Size : 47,8 Mb
Release : 2006
Category : Science
ISBN : 9780879698072

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Genomes by Hillary E. Sussman,Maria Ann Smit Pdf

Hundreds of genomes have been completely sequenced in the past decade, significantly advancing our understanding of genome structure and function. Genomescomprises a collection of review articles reprinted from the 10th Anniversary issue of the journal Genome Researchthat capture the status of genomic research in a selection of model species—from microbes to human. Written by leaders in the field, each chapter focuses on a kingdom, group, or species and offers a unique perspective on the history, the current status, and future of genomics research. Topics addressed include gene regulatory networks in the fruit fly and the sea squirt, fungal genome evolution, mouse and rat mutagenesis, the future of crop plant genomics, how livestock genomics informs human medicine, the importance of the dog genome in studying human disease, and the search for “humanness†through human and chimp genome comparison. In addition, updates on emerging technologies in DNA sequencing and in gene prediction, as well as direction to relevant public resources, are given. This book serves as a valuable reference and teaching tool for established scientists in the genomics field and as a comprehensive overview for those with more general interests in biology.

Author : J. Perry Gustafson,R.B. Flavell
Publisher : Springer Science & Business Media
Page : 245 pages
File Size : 45,8 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781461542353

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Genomes by J. Perry Gustafson,R.B. Flavell Pdf

This volume brings together the disciplines of plant and animal genome research, and serves as an opportunity for scientists from both fields to compare results, problems and prospects.

Author : Clyde R. Williams
Publisher : Nova Science Publishers
Page : 252 pages
File Size : 50,5 Mb
Release : 2006
Category : Genomes
ISBN : STANFORD:36105123240678

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Trends in Genome Research by Clyde R. Williams Pdf

The genomic approach of technology development and large-scale generation of community resource data sets has introduced an important new dimension in biological and biomedical research. Interwoven advances in genetics, comparative genomics, high throughput biochemistry and bioinformatics are combining to attack basic understanding of human life and disease and to develop strategies to combat disease. Genomic Research began with The Human Genome Project (HGP), the international research effort that determined the DNA sequence of the entire human genome, completed in April 2003. The HGP also included efforts to characterise and sequence the entire genomes of several other organisms, many of which are used extensively in biological research. Identification of the sequence or function of genes in a model organism is an important approach to finding and elucidating the function of human genes. Integral to the HGP are similar efforts to understand the genomes of various organisms commonly used in biomedical research, such as mice, fruit flies and roundworms. Such organisms are called "model organisms," because they can often serve as research models for how the human organism behaves. This book brings together leading research from throughout the world in this cutting-edge field.

Author : Janey Levy
Publisher : Gareth Stevens Publishing LLLP
Page : 34 pages
File Size : 48,8 Mb
Release : 2018-12-15
Category : Juvenile Nonfiction
ISBN : 9781538231371

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The Human Genome Project by Janey Levy Pdf

The Human Genome Project was a groundbreaking, life-altering development of the late 20th century and a major evolution in science and medicine. Readers of this remarkable volume will follow the scientists of the international, collaborative research program as they map the human genome. They'll learn about the science behind the project as well as the scientific and medical possibilities opened by it. Vivid photographs support the fascinating text, and sidebars, fact boxes, and captions enrich your reader's experience.

Author : Anonim
Publisher : DIANE Publishing
Page : 215 pages
File Size : 43,5 Mb
Release : 1988
Category : Gene mapping
ISBN : 9781428922587

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Mapping our genes : the genome projects : how big, how fast? by Anonim Pdf

Author : USDA Plant Genome Research Program
Publisher : Unknown
Page : 20 pages
File Size : 46,8 Mb
Release : 1991
Category : Plant genome mapping
ISBN : UIUC:30112046921430

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USDA Plant Genome Research Program by USDA Plant Genome Research Program Pdf

Author : Sándor Suhai
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 47,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461524519

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Computational Methods in Genome Research by Sándor Suhai Pdf

The application of computational methods to solve scientific and pratical problems in genome research created a new interdisciplinary area that transcends boundaries traditionally separating genetics, biology, mathematics, physics, and computer science. Computers have been, of course, intensively used for many year~ in the field of life sciences, even before genome research started, to store and analyze DNA or proteins sequences, to explore and model the three-dimensional structure, the dynamics and the function of biopolymers, to compute genetic linkage or evolutionary processes etc. The rapid development of new molecular and genetic technologies, combined with ambitious goals to explore the structure and function of genomes of higher organisms, has generated, however, not only a huge and burgeoning body of data but also a new class of scientific questions. The nature and complexity of these questions will require, beyond establishing a new kind of alliance between experimental and theoretical disciplines, also the development of new generations both in computer software and hardware technologies, respectively. New theoretical procedures, combined with powerful computational facilities, will substantially extend the horizon of problems that genome research can ·attack with success. Many of us still feel that computational models rationalizing experimental findings in genome research fulfil their promises more slowly than desired. There also is an uncertainity concerning the real position of a 'theoretical genome research' in the network of established disciplines integrating their efforts in this field.

Author : Diego A. Forero
Publisher : CRC Press
Page : 509 pages
File Size : 47,7 Mb
Release : 2021-12-23
Category : Science
ISBN : 9781000405682

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Bioinformatics and Human Genomics Research by Diego A. Forero Pdf

Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.

Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
Publisher : National Academies Press
Page : 329 pages
File Size : 55,7 Mb
Release : 2017-08-13
Category : Medical
ISBN : 9780309452885

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Human Genome Editing by National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations Pdf

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Author : Anonim
Publisher : Allied Publishers
Page : 276 pages
File Size : 51,6 Mb
Release : 1999
Category : Medical
ISBN : 8170238625

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Human Genome Research by Anonim Pdf

Contributed articles presented at an "International Symposium on Human Genome Studies: Emerging Ethical and Socio-Economical Issues" during May 22-25, 1998 in Goa.

Author : Jenny Reardon
Publisher : University of Chicago Press
Page : 320 pages
File Size : 54,9 Mb
Release : 2017-12-29
Category : Philosophy
ISBN : 9780226510453

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The Postgenomic Condition by Jenny Reardon Pdf

The postgenomic condition: an introduction -- The information of life or the life of information? -- Inclusion: can genomics be antiracist? -- Who represents the human genome? What is the human genome? -- Genomics for the people or the rise of the machines? -- Genomics for the 98 percent? -- The genomic open 2.0: the public v. the public -- Life on Third: knowledge and justice after the genome -- Epilogue