Hormesis

Author : Suresh I. S. Rattan,Marios Kyriazi
Publisher : Academic Press
Page : 326 pages
File Size : 54,9 Mb
Release : 2018-10-23
Category : Medical
ISBN : 9780128142547

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The Science of Hormesis in Health and Longevity by Suresh I. S. Rattan,Marios Kyriazi Pdf

The Science of Hormesis in Health and Longevity provides a comprehensive review of mild stress-induced physiological hormesis and its role in the maintenance and promotion of health. Coverage includes the underlying mechanisms of hormesis, including details of stress-response signaling, an enriched environment, positive challenges and dose-response mechanisms, amongst others. Research from top experts is presented to provide suggestions for developing novel therapeutic strategies, along with lifestyle interventions to promote health and homoeostasis. Researchers in aging and physiology, gerontologists, clinicians and medical students will find this a valuable addition for their work. Provides a comprehensive, scholarly review of the current state of hormesis in physiology, health, disease and aging Includes multiple perspectives and in-depth analysis by top experts involved in cutting-edge research to provide developing, novel therapeutic strategies, as well as lifestyle interventions Offers a clear understanding of hormesis’ underlying mechanisms, including details of stress-response signaling, an enriched environment, positive challenges, dose-response mechanisms, and more

Author : Mark P. Mattson,Edward J. Calabrese
Publisher : Springer Science & Business Media
Page : 219 pages
File Size : 43,8 Mb
Release : 2009-12-01
Category : Medical
ISBN : 9781607614951

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Hormesis by Mark P. Mattson,Edward J. Calabrese Pdf

Hormesis is a poorly understood phenomenon affecting all forms of life on earth. This groundbreaking book summarizes and analyzes the various positives of hormesis in an attempt to reveal hormesis as a fundamental principle of biomedical sciences as a whole.

Author : T. D. Luckey
Publisher : CRC Press
Page : 320 pages
File Size : 54,7 Mb
Release : 2020-10-28
Category : Law
ISBN : 9781000098723

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Radiation Hormesis by T. D. Luckey Pdf

Radiation Hormesis presents the only critical review of the effects of whole-body exposure to low doses of ionizing radiation in animals. This is a "must read" book for radiobiologists, health-conscious individuals, and serious environmentalists. Topics discussed include our radiation environment, radiation hormesis in cancer mortality, growth and development, reproduction and mutation, immunity, and cancer. Data is presented that indicates that low doses of ionizing radiation may actually be beneficial to human health. This information could invalidate the "zero thesis" and linear models used by most regulatory agencies. The implications regarding eliminating linear models and accepting radiation hormesis are also discussed.

Author : Charles L. Sanders
Publisher : Springer Science & Business Media
Page : 217 pages
File Size : 49,9 Mb
Release : 2009-11-07
Category : Medical
ISBN : 9783642037207

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Radiation Hormesis and the Linear-No-Threshold Assumption by Charles L. Sanders Pdf

Current radiation protection standards are based upon the application of the linear no-threshold (LNT) assumption, which considers that even very low doses of ionizing radiation can cause cancer. The radiation hormesis hypothesis, by contrast, proposes that low-dose ionizing radiation is beneficial. In this book, the author examines all facets of radiation hormesis in detail, including the history of the concept and mechanisms, and presents comprehensive, up-to-date reviews for major cancer types. It is explained how low-dose radiation can in fact decrease all-cause and all-cancer mortality and help to control metastatic cancer. Attention is also drawn to biases in epidemiological research when using the LNT assumption. The author shows how proponents of the LNT assumption consistently reject, manipulate, and deliberately ignore an overwhelming abundance of published data and falsely claim that no reliable data are available at doses of less than 100 mSv.

Author : Charles L. Sanders
Publisher : Springer
Page : 273 pages
File Size : 44,5 Mb
Release : 2017-08-08
Category : Medical
ISBN : 9783319563725

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Radiobiology and Radiation Hormesis by Charles L. Sanders Pdf

This book presents new information on radiobiology that more clearly refutes the linear no-threshold (LNT) assumption and supports radiation hormesis. Fresh light is cast on the mechanisms of radiation hormesis and the potential benefits of low-dose ionizing radiation in preventing and treating a wide variety of inflammatory and proliferative diseases. It is proposed that these effects may derive from cellular communication via electromagnetic waves directed by DNA, with each cell acting as a quantum computer. Readers will also find close analysis of the negative impacts of radiophobia on many aspects of modern life, including attitudes to imaging technologies, licensing of nuclear power reactors, and preparedness for survival of nuclear war. The book will be of interest to researchers and scientists in radiobiology, radiation protection, health physics, medical physics, and radiology. Specifically, it will provide medical physicians, radiation oncologists, radiation epidemiologists, gerontologists, cell biologists, toxicologists, and nuclear engineers with a wide range of interesting facts and enlightening novel perspectives.

Author : Eric Le Bourg,Suresh I.S. Rattan
Publisher : Springer Science & Business Media
Page : 188 pages
File Size : 42,5 Mb
Release : 2008-01-24
Category : Medical
ISBN : 9781402068690

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Mild Stress and Healthy Aging by Eric Le Bourg,Suresh I.S. Rattan Pdf

Whereas chronic stress has well known harmful effects, recent research shows that intermittent exposure of cells and organisms to mild stress can improve various biological parameters. This book brings together some of the world leaders in this area of research who present a critical analysis of the ongoing research with respect to the effects and mechanisms of action of various types of mild stress. Novel approaches to improving health and longevity are introduced.

Author : Edward J. Calabrese
Publisher : DIANE Publishing
Page : 32 pages
File Size : 46,9 Mb
Release : 2008-10
Category : Health & Fitness
ISBN : 9781437904611

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Should Hormesis Be the Default Model in Risk Assessment? by Edward J. Calabrese Pdf

Author : Edward J. Calabrese
Publisher : DIANE Publishing
Page : 20 pages
File Size : 54,6 Mb
Release : 2008-06
Category : Science
ISBN : 9781437902235

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Hormesis and the Law: Toxic Torts by Edward J. Calabrese Pdf

Author : Suresh I. S. Rattan,Éric Le Bourg
Publisher : CRC Press
Page : 382 pages
File Size : 48,9 Mb
Release : 2014-05-16
Category : Medical
ISBN : 9781482205466

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Hormesis in Health and Disease by Suresh I. S. Rattan,Éric Le Bourg Pdf

Some mild stresses have positive effects on survival and aging as shown in animal models. There is also a large body of research that demonstrates these hormetic effects on aging, health, and resistance to severe stresses and diseases in human beings. However, the data are dispersed in the literature and are not always interpreted as hormetic effects. Hormesis in Health and Disease reviews the evidence for hormesis in humans as achieved through a variety of stresses or stimuli, and discusses mechanisms of hormesis and its ethical and legal issues. Divided into four sections, this book presents the current state of research, including questions, debates, doubts, and controversies in hormesis. Section I covers the history and terminology of hormesis, describing its main features and providing necessary background information. Section II shows that hormetic effects can be caused by various stresses—including physical exercise, nutritional components, fasting, micronutrients, irradiation, heat, ischemia, and mental challenge—and can be observed both in organs and at the organism level. Section III reviews possible mechanisms of hormesis that have been elucidated at this point. Section IV discusses the wider consequences hormesis may have for everyone. This book demonstrates that health beneficial hormetic effects do exist in human beings. It offers information to inspire key players to initiate new strategies to elucidate the strengths and limits of the dual nature of stress.

Author : T. D. Luckey
Publisher : CRC Press
Page : 233 pages
File Size : 55,7 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9781000006209

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Hormesis With Ionizing Radiation by T. D. Luckey Pdf

First published in 1980: The purpose of this Monograph, Hormesis With Ionizing Radiation, are to crystalize scattered information into an accepted subject of science and to awaken our society to new potential uses of ionizing radiation.

Author : David Costantini
Publisher : Springer Science & Business Media
Page : 348 pages
File Size : 44,9 Mb
Release : 2014-03-27
Category : Science
ISBN : 9783642546631

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Oxidative Stress and Hormesis in Evolutionary Ecology and Physiology by David Costantini Pdf

This book discusses oxidative stress and hormesis from the perspective of an evolutionary ecologist or physiologist. In the first of ten chapters, general historical information, definitions, and background of research on oxidative stress physiology, hormesis, and life history are provided. Chapters 2-10 highlight the different solutions that organisms have evolved to cope with the oxidative threats posed by their environments and lifestyles. The author illustrates how oxidative stress and hormesis have shaped diversity in organism life-histories, behavioral profiles, morphological phenotypes, and aging mechanisms. The book offers fascinating insights into how organisms work and how they evolve to sustain their physiological functions under a vast array of environmental conditions.

Author : Marios Kyriazis
Publisher : Bentham Science Publishers
Page : 270 pages
File Size : 46,5 Mb
Release : 2016-08-30
Category : Science
ISBN : 9781681083353

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Challenging Aging The Anti-senescence Effects of Hormesis, Environmental Enrichment and Information Exposure by Marios Kyriazis Pdf

Age-related degeneration may be reduced or even eliminated, by positively challenging the human being, physically or cognitively, to up-regulate somatic repair functions. Exposure to meaningful information and a challenging environment act as hormetic stressors which, in the context of an increasingly technological setting, may invoke evolutionary mechanisms that lead to a persistent maintenance of homeostasis. Thus, there is a strong link between environmental factors and ongoing health, leading to an individual’s ability to continually adapt to age related challenges. Challenging Ageing: The Anti-senescence Effects of Hormesis, Environmental Enrichment, and Information Exposure explains the role of hormesis in anti-aging processes followed by information on vitagenes, epigenetics, environmental enrichment and germlines. The monograph also brings newer concepts and theories to the fore, such as ‘environmental enrichment’ and ‘technoculture.’ Medical professionals and general readers, alike, will gain a a new perspective on the processes that counter aging processes in the human being.

Author : T. D. Luckey
Publisher : CRC Press
Page : 216 pages
File Size : 55,8 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9781000013023

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Hormesis With Ionizing Radiation by T. D. Luckey Pdf

First published in 1980: The purpose of this Monograph, Hormesis With Ionizing Radiation, are to crystalize scattered information into an accepted subject of science and to awaken our society to new potential uses of ionizing radiation.

Author : Miles Hacker,William S. Messer,Kenneth A. Bachmann
Publisher : Academic Press
Page : 608 pages
File Size : 48,6 Mb
Release : 2009-06-19
Category : Medical
ISBN : 0080919227

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Pharmacology by Miles Hacker,William S. Messer,Kenneth A. Bachmann Pdf

Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research. Uses individual drugs to explain molecular actions Full color art program explains molecular and chemical concepts graphically Logical structure reflecting the current state of pharmacology and translational research Covers such intricacies as drug resistance and cell death Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Author : Thormod Henriksen
Publisher : CRC Press
Page : 241 pages
File Size : 53,5 Mb
Release : 2002-09-05
Category : Science
ISBN : 9780203166352

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Radiation and Health by Thormod Henriksen Pdf

Radiation and the effects of radioactivity have been known for more than 100 years. International research spanning this period has yielded a great deal of information about radiation and its biological effects and this activity has resulted in the discovery of many applications in medicine and industry including cancer therapy, medical diagnostics