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Author : Philippe Guilpain,Danièle Noël,Jérôme Avouac
Publisher : Frontiers Media SA
Page : 253 pages
File Size : 50,5 Mb
Release : 2021-11-29
Category : Medical
ISBN : 9782889717446
Author : Wei Wang,Lixin Zheng
Publisher : Frontiers Media SA
Page : 147 pages
File Size : 48,6 Mb
Release : 2023-11-01
Category : Medical
ISBN : 9782832538197
Author : Aehlert,Robert Vroman
Publisher : Jones & Bartlett Publishers
Page : 1567 pages
File Size : 43,5 Mb
Release : 2011
Category : Medical
ISBN : 9780323085359
"Providing the tools you need to succeed, the two-volume set of Paramedic Practice Today: Above and Beyond offers a solid foundation for paramedic practice and is now updated to reflect the 2010 emergency cardiovascular care guidelines! A conversational, easy-to-read style simplifies topics and helps you master National Standard Curriculum objectives and meet the new National Education Standards. Each volume includes a companion DVD-ROM with step-by-step videos demonstrating the skills in the textbook and more. Because this two-volume set corresponds to the National Registry of EMTs National EMS Practice Analysis, it provides you with the best possible preparation for the National Registry exam."--Publisher's website.
Author : Carlo Perricone,Yehuda Shoenfeld
Publisher : Academic Press
Page : 720 pages
File Size : 42,6 Mb
Release : 2019-02-08
Category : Medical
ISBN : 9780128143087
The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications
Author : Sir William Osler
Publisher : New York : D. Appleton
Page : 1116 pages
File Size : 51,5 Mb
Release : 1892
Category : Diseases
ISBN : UOM:39015036652991
Copy 2, Gift of Mrs. E. Carwile LeRoy, 2009.
Author : Ajay K. Singh,Joseph Loscalzo
Publisher : Oxford University Press, USA
Page : 1135 pages
File Size : 48,8 Mb
Release : 2012
Category : Medical
ISBN : 9780195366273
Based upon the popular review course from Harvard Medical School, The Brigham Intensive Review of Internal Medicine is a comprehensive study guide for the American Board of Internal Medicine certification or maintenance of certification examination as well as for general practice review by physicians and residents. This authoritative, thorough resource provides in-depth coverage on all specialties of internal medicine, as well as palliative care, occupational medicine, psychiatry, and geriatric medicine. Editors Ajay K. Singh and Joseph Loscalzo recruited leading authorities from Harvard as well as former chief residents at Brigham and Women's Hospital to contribute to this book. Featuring over 600 board review questions, with numerous tables and figures, chapters offer detailed discussions with emphasis on essential learning points. Over 100 chapters are organized into 10 broad sections, with one additional section dedicated to board simulation. As the required content for the American Board of Internal Medicine continues to evolve, studying can prove challenging. The Brigham Intensive Review of Internal Medicine is the ideal study guide for anyone preparing for certification or recertification.
Author : Drew Provan,Hillard M. Lazarus
Publisher : John Wiley & Sons
Page : 452 pages
File Size : 45,9 Mb
Release : 2024-03-05
Category : Medical
ISBN : 9781394180479
Provides a core knowledgebase for those with minimal exposure to hematologic molecular biology, fully revised and updated Molecular Hematology brings together the most up-to-date and reliable information on the molecular basis of major hematologic diseases. Edited and authored by leading experts in the field, this volume demonstrates the clinical relevance of molecular biology in the diagnosis and treatment of blood disorders. Concise, accessible chapters address key topics in modern hematology, such as lymphoma genetics, molecular coagulation, thrombophilia, pharmacogenomics, platelet disorders, hemophilia, anemia, and multiple myeloma. Chapters introduce and summarize specific hematologic diseases, explore the pathogenesis of the disorder, highlight new and emerging molecular strategies, and more. Now in its fifth edition, Molecular Hematology is fully revised to incorporate contemporary hematology research and practice. Entirely new chapters cover topics such as CAR-T cell technology, COVID, cancer cell biology, gene therapy and gene editing in clinical practice, as well as the impact of molecular research on the diagnosis and treatment of various malignant hematologic diseases. This edition includes updated suggested readings and a wealth of new full-color charts, graphs, and illustrations throughout. Covers the molecular biology of different blood diseases, their pathogeneses, and current molecular research and therapies Illustrates the impact of molecular research on hematologic investigations and therapeutics Discusses how progress in basic science and therapeutics has improved the diagnosis and care of patients with various hematologic disorders Surveys recent developments in cancer-cell biology, with an emphasis on leukemia and lymphoma Includes access to a companion Digital Edition providing search across the book, downloadable illustrations, and notation tools Molecular Hematology is a must-have resource for established and trainee clinicians, clinical scientists and researchers, medical students, and upper-level undergraduates in the fields of hematology, oncology, and molecular biology.
Author : Ajay K. Singh,Joseph Loscalzo
Publisher : Elsevier Health Sciences
Page : 1100 pages
File Size : 52,9 Mb
Release : 2017-12-31
Category : Medical
ISBN : 9780323597197
Based on the popular review course from Harvard Medical School, The Brigham Intensive Review of Internal Medicine, 3rd Edition, provides in-depth coverage on all specialties of internal medicine, as well as palliative care, occupational medicine, psychiatry, and geriatric medicine. Ideal for preparing for certification or recertification, this highly regarded review tool keeps you up to date with tremendous changes in the field, incorporating detailed discussions in every chapter, essential learning points, more than 600 review questions, numerous tables and figures, and more. Includes three new chapters: Sedation Agitation-Sleep Deprviation; Hepatitis B and C; and Evaluation of the Dyspneic Patient. Features a brand new, full-color design with all-new diagrams and color photos. Provides extensively revised information throughout, including more MOC-focused content.
Author : Ajay K. Singh,Joseph Loscalzo
Publisher : Oxford University Press, USA
Page : 1185 pages
File Size : 47,7 Mb
Release : 2014
Category : Medical
ISBN : 9780199358274
Based upon the popular review course from Harvard Medical School, The Brigham Intensive Review of Internal Medicine is a comprehensive study guide for the American Board of Internal Medicine certification or maintenance of certification examination as well as for general practice review by physicians and residents. This authoritative, thorough resource provides in-depth coverage on all specialties of internal medicine, as well as palliative care, occupational medicine, psychiatry, and geriatric medicine. Editors Ajay K. Singh and Joseph Loscalzo recruited leading authorities from Harvard as well as former chief residents at Brigham and Women's Hospital to contribute to this book. Featuring over 600 board review questions, with numerous tables and figures, chapters offer detailed discussions with emphasis on essential learning points. Over 100 chapters are organized into 10 broad sections, with one additional section dedicated to board simulation. As the required content for the American Board of Internal Medicine continues to evolve, studying can prove challenging. The Brigham Intensive Review of Internal Medicine is the ideal study guide for anyone preparing for certification or recertification.
Author : Dilip Ghosh
Publisher : Academic Press
Page : 476 pages
File Size : 45,9 Mb
Release : 2020-11-12
Category : Health & Fitness
ISBN : 9780128206102
Nutraceuticals in Brain Health and Beyond focuses on a variety of health disorders where intervention with nutritional supplements prove valuable, such as Alzheimer’s, Parkinson’s, autism, and attention-deficit disorder in children. In addition, Nutraceuticals in Brain Health and Beyond addresses "herb-nutra psychiatry" which is a field of research focused on developing a comprehensive, cohesive, and scientifically rigorous evidence base to shift conceptual thinking around the role of diet and nutrition in mental health. Intended for nutrition researchers, nutritionists, dieticians, regulatory bodies, health professionals, and students studying related fields, Nutraceuticals in Brain Health and Beyond will be a useful reference in understanding the links between nutrition and brain health. • Addresses nutritional psychiatry and cognitive health at all stages of the lifespan • Contains extensive coverage of vitamins, minerals, botanicals, and other nutrients • Offers novel insight into cognitive dysfunctions including depression and other neurodegenerative disorders • Explores the role of genomics and epigenetics, including discussion of the gut–brain axis
Author : Serge Nataf,Roland S. Liblau,Guillaume Dorothee,Stéphane Hunot
Publisher : Frontiers Media SA
Page : 136 pages
File Size : 45,8 Mb
Release : 2021-06-01
Category : Medical
ISBN : 9782889668311
Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 570 pages
File Size : 55,8 Mb
Release : 2011-12-30
Category : Science
ISBN : 9780309219396
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Author : Javier Velázquez-Moctezuma,Emilio Domínguez-Salazar,Beatriz Gómez-González
Publisher : Frontiers E-books
Page : 120 pages
File Size : 46,6 Mb
Release : 2014-10-10
Category : Electronic book
ISBN : 9782889192748
Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro-immune interactions. Brain was shown to be under the continuous surveillance of the immune system, even under basal physiological conditions in the absence of any pathology. Likely, it was found a profuse nervous innervation of lymphoid organs and even of single immune cells. Gates for direct neural immune communication were found both centrally and peripherally. Centrally, the gates, but also the fences, were situated at the brain barriers, the blood-brain barrier and the blood-cerebrospinal fluid barrier, and at the circunventricular organs. Peripherally, the fences constituted the apparent diverse nature of molecules involved in neural and immune signaling; however, time proved that both system were capable of producing the same signaling molecules and also systematically responded to the molecules released by the other system. Therefore, the gates were open for direct neural-immune communication at the peripheral level. This Research Topic aimed to include original reports, reviews and technical reports regarding the description of the gates and fences in neural immune interactions. We intended to provide an extensive view of the mechanisms governing central and peripheral neural-immune interactions, and the role of the borders, the blood-neural barriers, in the regulation of the neural-immune communication.
Author : Maryam Mahmoudi,Nima Rezaei
Publisher : Springer
Page : 515 pages
File Size : 50,7 Mb
Release : 2019-07-30
Category : Medical
ISBN : 9783030160739
This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation. Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.
Author : Alberta Hoi
Publisher : Springer Nature
Page : 192 pages
File Size : 43,7 Mb
Release : 2021-11-15
Category : Medical
ISBN : 9783030851613
The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.