Management Of Breast Cancer In Older Women

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Management of Breast Cancer in Older Women

Author : Malcolm W. Reed,Riccardo A. Audisio
Publisher : Springer Science & Business Media
Page : 408 pages
File Size : 45,6 Mb
Release : 2010-01-18
Category : Medical
ISBN : 9781848002654

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Management of Breast Cancer in Older Women by Malcolm W. Reed,Riccardo A. Audisio Pdf

I was looking at Mrs T – all 45 kilos of her – with somewhat puzzled thoughts. I had prescribed her capecitabine at very prudent doses, in view of her 91-year-old kidneys and physiology. She had reduced my treatment even further, “because it was making her tired.” As a result, she was taking a grand total of 500 mg of capecitabine a day. Yet, her metastatic, ER/PR-negative, Her2-positive breast cancer was undoubtedly responding. Her pain was improving and her chest mass was shrinking, as were her lung metastases... What was the secret of that response? Were Mrs T’s kidneys eli- nating even less drug than predicted by her creatinine clearance? Was her sarcopenia altering drug distribution? Was she absorbing more drug than average? Or was her tumor exquisitely sensitive to fluoropyrimidines? “Physicians,” said Voltaire, “pour drugs they know little for diseases they know even less into patients they know no- ing about.” Medicine has made tremendous progress since the eighteenth century. Yet, there are fields where quite a lot remains to be learned. In developed countries, 25% of breast cancers occur in patients aged 75 years and older. Yet, these patients represent only 4% of the population of traditional clinical trials. That ought to let us wonder how relevant data acquired in patients in their 60s are to a nonagenarian. Fortunately, geriatric oncologists have been stepping up to the task and have gen- ated data to help us to treat such patients.

Management of Breast Cancer in Older Women

Author : Malcolm W. R. Reed,Riccardo A. Audisio
Publisher : Unknown
Page : 128 pages
File Size : 50,8 Mb
Release : 2019
Category : Breast
ISBN : 3030118762

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Management of Breast Cancer in Older Women by Malcolm W. R. Reed,Riccardo A. Audisio Pdf

This book offers evidence-based clinical knowledge of older patients suffering from breast cancer. It details the full armament of therapeutic options as well as the epidemiology of the disease and specific psychosocial considerations for elderly patients.

Adjuvant Therapy of Breast Cancer

Author : I. Craig Henderson
Publisher : Springer
Page : 488 pages
File Size : 52,7 Mb
Release : 1992-08-31
Category : Medical
ISBN : UOM:39015025380216

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Adjuvant Therapy of Breast Cancer by I. Craig Henderson Pdf

The results of randomized trials evaluating the use of early or adjuvant systemic treatment for patients with resectable breast cancer provide an eloquent rebuttal to those who would argue that we have made no progress in the treatment of cancer. Many of the tumors that we have been most successful in curing with chemotherapy and other newer forms of treatment are relatively uncommon. In contrast, breast cancer continues to be the single most common malignancy among women in the western world, is increasingly a cause of death throughout Asia and Third-World countries, and remains one of the most substantial causes of cancer mortality world wide. The use of mammography as a means of early detection has been shown to reduce breast cancer mortality by 25-35% among those popu lations in which it is utilized. The use of adjuvant systemic treatment in appropriate patients provides a similar (and additional) reduction in breast cancer mortality. Few subjects have been so systematically studied in the history of medicine, and it seems fair to conclude that the value to adjuvant systemic therapy in prolonging the lives of women with breast cancer is more firmly supported by empirical evidence than even the more conventional or primary treatments using various combinations ofsurgery and radiotherapy.

Cancer in the Elderly

Author : Carrie P. Hunter,Karen A. Johnson,Hyman B. Muss
Publisher : CRC Press
Page : 591 pages
File Size : 48,8 Mb
Release : 2000-03-01
Category : Medical
ISBN : 9780824746452

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Cancer in the Elderly by Carrie P. Hunter,Karen A. Johnson,Hyman B. Muss Pdf

This book presents comprehensive assessment and up-to-date discussion of the epidemiology, prevention, and treatment of cancer in the elderly, highlighting the growing demands of the disease, its biology, individual susceptibility, the impact of state-of-the-art and emerging therapies on reducing morbidity, and decision making processes. Describ

Management of Gynecological Cancers in Older Women

Author : Stuart M. Lichtman,Riccardo A. Audisio
Publisher : Springer Science & Business Media
Page : 418 pages
File Size : 48,5 Mb
Release : 2013-01-11
Category : Medical
ISBN : 9781447146056

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Management of Gynecological Cancers in Older Women by Stuart M. Lichtman,Riccardo A. Audisio Pdf

This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older gynecological cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.

Management of Cancer in the Older Patient E-Book

Author : Arash Naeim,David Reuben,Patricia Ganz
Publisher : Elsevier Health Sciences
Page : 310 pages
File Size : 50,6 Mb
Release : 2011-08-17
Category : Medical
ISBN : 9781455723133

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Management of Cancer in the Older Patient E-Book by Arash Naeim,David Reuben,Patricia Ganz Pdf

Management of Cancer in the Older Patient, by Drs. Arash Naeim, David Reuben, and Patricia Ganz, offers the help you need to effectively diagnose, refer, and manage cancer in geriatric patients. You’ll see how to provide effective cancer screening; refer your patients to the right oncologist; deal with comorbidities, frailties, and other complications; navigate end-of-life issues; and much more. A templated, user-friendly format makes it easy to find and apply the answers you need. See how to best manage geriatric cancer patients with help from leading specialists in both geriatrics and oncology Make informed decisions as to when to refer patients to specialists. Provide the supportive care your patients and their families need on issues such as such as mental health, pain, fatigue, nausea, insomnia. Be prepared to help cancer survivors navigate their after-treatment care including adjuvant therapy, side effects, second cancers, quality of life, and other concerns. Offer accurate guidance on ethical issues like competency, end of life, hospice, the role of the caregiver, and more.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 54,9 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

The Next Four Decades

Author : Grayson K. Vincent
Publisher : Unknown
Page : 16 pages
File Size : 53,5 Mb
Release : 2010
Category : Aging
ISBN : IND:30000135107997

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The Next Four Decades by Grayson K. Vincent Pdf

The purpose of this report is to present information on how the age structure of the overall population and the composition of the older population in terms of age, sex, race, and Hispanic origin are expected to change over the next four decades. Between 2010 and 2050, the United States is projected to experience rapid growth in its older population. In 2050, the number of Americans aged 65 and older is projected to be 88.5 million, more than double its projected population of 40.2 million in 2010. The baby boomers are largely responsible for this increase in the older population, as they will begin crossing into this category in 2011. The aging of the population will have wide-ranging implications for the country. As the United States ages over the next several decades, its older population will become more racially and ethnically diverse. Projecting the size and structure, in terms of age, sex, race, and Hispanic origin, of the older population is important to public and private interests, both socially and economically. The projected growth of the older population in the United States will present challenges to policy makers and programs, such as Social Security and Medicare. It will also affect families, businesses, and health care providers.

Meeting Psychosocial Needs of Women with Breast Cancer

Author : National Research Council,Institute of Medicine,National Cancer Policy Board
Publisher : National Academies Press
Page : 289 pages
File Size : 55,5 Mb
Release : 2004-04-12
Category : Medical
ISBN : 9780309091299

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Meeting Psychosocial Needs of Women with Breast Cancer by National Research Council,Institute of Medicine,National Cancer Policy Board Pdf

In Meeting Psychosocial Needs of Women with Breast Cancer, the National Cancer Policy Board of the Institute of Medicine examines the psychosocial consequences of the cancer experience. The book focuses specifically on breast cancer in women because this group has the largest survivor population (over 2 million) and this disease is the most extensively studied cancer from the standpoint of psychosocial effects. The book characterizes the psychosocial consequences of a diagnosis of breast cancer, describes psychosocial services and how they are delivered, and evaluates their effectiveness. It assesses the status of professional education and training and applied clinical and health services research and proposes policies to improve the quality of care and quality of life for women with breast cancer and their families. Because cancer of the breast is likely a good model for cancer at other sites, recommendations for this cancer should be applicable to the psychosocial care provided generally to individuals with cancer. For breast cancer, and indeed probably for any cancer, the report finds that psychosocial services can provide significant benefits in quality of life and success in coping with serious and life-threatening disease for patients and their families.

Breast Cancer in Young Women

Author : Oreste Gentilini,Ann H. Partridge,Olivia Pagani
Publisher : Springer Nature
Page : 218 pages
File Size : 48,9 Mb
Release : 2020-02-07
Category : Medical
ISBN : 9783030247621

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Breast Cancer in Young Women by Oreste Gentilini,Ann H. Partridge,Olivia Pagani Pdf

This contributed book covers all aspects concerning the clinical scenario of breast cancer in young women, providing physicians with the latest information on the topic. Young women are a special subset of patients whose care requires dedicated expertise. The book, written and edited by internationally recognized experts who have been directly involved in the international consensus guidelines for breast cancer in young women, pays particular attention to how the disease and its planned treatment can be effectively communicated to young patients. Highly informative and carefully structured, it provides both theoretical and practice-oriented insight for practitioners and professionals involved in the different phases of treatment, from diagnosis to intervention, to follow-up – without neglecting the important role played by prevention.

WHO Classification of Breast Tumours

Author : WHO Classification of Tumours Editorial Board
Publisher : International Agency for Research on Cancer
Page : 0 pages
File Size : 52,9 Mb
Release : 2019-11-21
Category : Medical
ISBN : 9283245008

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WHO Classification of Breast Tumours by WHO Classification of Tumours Editorial Board Pdf

Table of contents : - TNM staging of carcinomas of the breast - 1. Introduction to tumours of the breast - 2. Epithelial tumours of the breast - 3. Fibroepithelial tumours and hamartomas of the breast - 4. Tumours of the nipple - 5. Mesenchymal tumours of the breast - 6. Haematolymphoid tumours of the breast - 7. Tumours of the male breast - 8. Metastases to the breast - 9. Genetic tumours syndromes of the breast.

Breast Cancer Essentials

Author : Mahdi Rezai,Mehmet Ali Kocdor,Nuh Zafer Canturk
Publisher : Springer Nature
Page : 665 pages
File Size : 47,8 Mb
Release : 2021-08-27
Category : Medical
ISBN : 9783030731472

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Breast Cancer Essentials by Mahdi Rezai,Mehmet Ali Kocdor,Nuh Zafer Canturk Pdf

Breast cancer is a disease requiring multidisciplinary management including surgery, medical and radiation oncology, radiology, pathology, nuclear medicine, genetic counseling, and psychological support. Each member of the team needs to be updated continuously on breast cancer treatment because of its rapidly changing nature. From the diagnostic procedures to operations and even in metastatic stages of breast cancer, surgeons play an essential part in multidisciplinary teams. After standard surgical options, oncoplastic breast surgery is rapidly becoming one of the most important surgical topics that should be learned by attending surgeons. The idea of writing this book stemmed from a collaboration between the European Academy of Senology (EAoS), European Institute of Oncology (IEO), Euro-Asian Society of Mastology (ESOMA), and SENATURK (Turkish Academy of Senology), which have been working together to promote better training in breast care for professionals. The book offers invaluable support for breast surgeons by covering critical and essential information in senology. It will also greatly benefit the other members of multidisciplinary teams, surgery residents, gynecologists, and plastic and reconstructive surgeons.

Breast Disease

Author : Adnan Aydiner,Abdullah İgci,Atilla Soran
Publisher : Springer
Page : 934 pages
File Size : 43,7 Mb
Release : 2016-05-09
Category : Medical
ISBN : 9783319260129

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Breast Disease by Adnan Aydiner,Abdullah İgci,Atilla Soran Pdf

This second volume of the handbook on breast disease provides a comprehensive overview of its clinical management and current therapies. It brings readers up to speed with the latest guidelines and therapeutic regimens in breast cancer and provides and in-depth account of current and new therapeutic approaches. Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget’s disease and phyllodes tumors, and a section on supportive and follow-up care. By adopting a multidisciplinary approach to breast cancer, this book is a must- have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

Adjuvant Therapy for Breast Cancer

Author : Monica Castiglione,Martine J. Piccart
Publisher : Springer Science & Business Media
Page : 483 pages
File Size : 41,9 Mb
Release : 2009-07-11
Category : Medical
ISBN : 9780387751153

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Adjuvant Therapy for Breast Cancer by Monica Castiglione,Martine J. Piccart Pdf

Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.

Cancer and Aging

Author : M. Extermann
Publisher : Karger Medical and Scientific Publishers
Page : 178 pages
File Size : 48,9 Mb
Release : 2013-01-18
Category : Medical
ISBN : 9783318023077

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Cancer and Aging by M. Extermann Pdf

Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.