Model Systems To Study The Mechanisms Of Neural Development And Disease

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Model Systems to Study the Mechanisms of Neural Development and Disease

Author : Parthiv Haldipur,Paula Alexandre,Sumru Bayin
Publisher : Frontiers Media SA
Page : 167 pages
File Size : 43,9 Mb
Release : 2024-06-29
Category : Science
ISBN : 9782889767076

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Model Systems to Study the Mechanisms of Neural Development and Disease by Parthiv Haldipur,Paula Alexandre,Sumru Bayin Pdf

From Neurons to Neighborhoods

Author : National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
Publisher : National Academies Press
Page : 610 pages
File Size : 40,5 Mb
Release : 2000-11-13
Category : Social Science
ISBN : 9780309069885

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From Neurons to Neighborhoods by National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development Pdf

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Molecular Mechanisms of Neural Development and Insights into Disease

Author : Anonim
Publisher : Academic Press
Page : 546 pages
File Size : 46,5 Mb
Release : 2021-03-09
Category : Science
ISBN : 9780128152829

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Molecular Mechanisms of Neural Development and Insights into Disease by Anonim Pdf

Neural Development and Disease, Volume 142 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters by one or more members of an international board of authors. Sections in this new release cover The role of primary cilia in neural development and disease, Mechanisms of axon guidance receptor regulation and signaling, Synaptic recognition molecules in development and disease, The regulation of cortical neurogenesis, Axon guidance in the developing spinal cord, The role of astrocytes in synapse formation and maturation, Development of motor circuits, Molecular mechanisms that mediate dendrite morphogenesis, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series

Model Systems of Development and Aging of the Nervous System

Author : Antonia Vernadakis,Alain M. Privat,Jean M. Lauder,Paola S. Timiras
Publisher : Springer
Page : 516 pages
File Size : 47,7 Mb
Release : 2011-10-14
Category : Medical
ISBN : 1461292123

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Model Systems of Development and Aging of the Nervous System by Antonia Vernadakis,Alain M. Privat,Jean M. Lauder,Paola S. Timiras Pdf

The last decade has generated a multitude of studies using in vitro model systems to explore growth and differentiation of the nervous system. Although the findings have been exciting and have revealed unique properties of neural cells, considerable concern continues to be expressed regarding the significance of in vitro findings in terms of their applicability to in vivo biological events. To examine this issue further, a group of scientists pre sented and discussed their findings at a conference sponsored by the Institute of Developmental Neuroscience and Aging held in Crete, Greece, 26-29 May 1985. The conference was cosponsored by the University of Crete and was generously supported by the Ministry of Research and Technology of Greece, Tourism Organization of Greece, and also Sandoz and FIDIA. The Directors of the Institute of Developmental Neuroscience and Aging are indebted to these Institutions for their support. For the success of this conference, the Directors owe much to Drs. Eleni Fleischer-Lambropoulos and Yiannis Tsouderos, who spent countless hours in making arrangements so that the participants would have not only a scientific, but also a unique cultural, experience. Several chapters of this book focus on the complex phenomena of neurogenesis and gliogenesis, and the modulation of neuronal differentiation. The concept that neuronal differentiation has both genetic and epigenetic components is documented by elegant studies using both in vitro cultured cells and neurons transplanted in vivo.

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
Publisher : National Academies Press
Page : 348 pages
File Size : 42,9 Mb
Release : 2000-12-21
Category : Nature
ISBN : 9780309070867

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Scientific Frontiers in Developmental Toxicology and Risk Assessment by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology Pdf

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee on Guidelines for the Use of Animals in Neuroscience and Behavioral Research
Publisher : National Academies Press
Page : 223 pages
File Size : 42,8 Mb
Release : 2003-08-22
Category : Science
ISBN : 9780309167857

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Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee on Guidelines for the Use of Animals in Neuroscience and Behavioral Research Pdf

Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Disease Control Priorities, Third Edition (Volume 8)

Author : Donald A. P. Bundy,Nilanthi de Silva,Susan Horton,Dean T. Jamison
Publisher : World Bank Publications
Page : 502 pages
File Size : 45,7 Mb
Release : 2017-11-20
Category : Medical
ISBN : 9781464804397

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Disease Control Priorities, Third Edition (Volume 8) by Donald A. P. Bundy,Nilanthi de Silva,Susan Horton,Dean T. Jamison Pdf

More children born today will survive to adulthood than at any time in history. It is now time to emphasize health and development in middle childhood and adolescence--developmental phases that are critical to health in adulthood and the next generation. Child and Adolescent Health and Development explores the benefits that accrue from sustained and targeted interventions across the first two decades of life. The volume outlines the investment case for effective, costed, and scalable interventions for low-resource settings, emphasizing the cross-sectoral role of education. This evidence base can guide policy makers in prioritizing actions to promote survival, health, cognition, and physical growth throughout childhood and adolescence.

Biology of the NMDA Receptor

Author : Antonius M. VanDongen
Publisher : CRC Press
Page : 368 pages
File Size : 51,7 Mb
Release : 2008-10-29
Category : Medical
ISBN : 9781420044157

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Biology of the NMDA Receptor by Antonius M. VanDongen Pdf

The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Translational Research in Traumatic Brain Injury

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 45,9 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

The Neural Crest

Author : Nicole Le Douarin,Chaya Kalcheim
Publisher : Cambridge University Press
Page : 494 pages
File Size : 52,5 Mb
Release : 1999-11-28
Category : Medical
ISBN : 0521620104

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The Neural Crest by Nicole Le Douarin,Chaya Kalcheim Pdf

This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Etiology of Parkinson's Disease

Author : Jonas H. Ellenberg,William C. Koller,James William Langston
Publisher : CRC Press
Page : 600 pages
File Size : 45,8 Mb
Release : 1995-03-01
Category : Medical
ISBN : 0824788230

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Etiology of Parkinson's Disease by Jonas H. Ellenberg,William C. Koller,James William Langston Pdf

This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

The Enteric Nervous System

Author : John Barton Furness,Marcello Costa
Publisher : Unknown
Page : 312 pages
File Size : 52,7 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015012463215

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The Enteric Nervous System by John Barton Furness,Marcello Costa Pdf

Brain Transcriptome

Author : Anonim
Publisher : Academic Press
Page : 365 pages
File Size : 40,5 Mb
Release : 2014-08-27
Category : Science
ISBN : 9780128013199

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Brain Transcriptome by Anonim Pdf

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume, concentrates on the brain transcriptome. Brings together cutting-edge research on the brain transcriptome

Clinical Neuroembryology

Author : Hans J. ten Donkelaar,Martin Lammens,Akira Hori
Publisher : Springer Science & Business Media
Page : 544 pages
File Size : 47,8 Mb
Release : 2006-09-07
Category : Medical
ISBN : 9783540346593

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Clinical Neuroembryology by Hans J. ten Donkelaar,Martin Lammens,Akira Hori Pdf

Progress in developmental neurobiology and advances in (neuro) genetics have been spectacular. The high resolution of modern imaging techniques applicable to developmental disorders of the human brain and spinal cord have created a novel insight into the developmental history of the central nervous system (CNS). This book provides a comprehensive overview of the development of the human CNS in the context of its many developmental disorders. It provides a unique combination of data from human embryology, animal research and developmental neuropathology, and there are more than 400 figures in over a hundred separate illustrations.

Mechanisms of Cellular Differentiation, Organ Development, and Novel Model Systems

Author : Benedetta Artegiani,Delilah Hendriks,Kai Kretzschmar
Publisher : Frontiers Media SA
Page : 383 pages
File Size : 54,8 Mb
Release : 2022-09-29
Category : Science
ISBN : 9782832501191

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Mechanisms of Cellular Differentiation, Organ Development, and Novel Model Systems by Benedetta Artegiani,Delilah Hendriks,Kai Kretzschmar Pdf