Molecular Toxicology

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Molecular and Biochemical Toxicology

Robert C. Smart,Ernest Hodgson
Molecular and Biochemical Toxicology Book PDF

Author : Robert C. Smart,Ernest Hodgson
Publisher : John Wiley & Sons
Page : 1040 pages
File Size : 53,7 Mb
Release : 2017-11-06
Category : Science
ISBN : 9781119042433

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Molecular and Biochemical Toxicology by Robert C. Smart,Ernest Hodgson Pdf

Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Molecular Toxicology

P. David Josephy,Bengt Mannervik
Molecular Toxicology Book PDF

Author : P. David Josephy,Bengt Mannervik
Publisher : Unknown
Page : 620 pages
File Size : 51,8 Mb
Release : 2006
Category : Molecular toxicology
ISBN : 0195176200

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Molecular Toxicology by P. David Josephy,Bengt Mannervik Pdf

The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and molecular biological experimental techniques have helped researchers understand the precise effects of toxins and foreign compounds on living things atthe molecular, cellular, and organismal levels. Breakthrough research has recently been completed illuminating the human genome and the role of enzymes in toxic biochemical reaction mechanisms. Toxicology now covers drug metabolism and design, carcinogenesis, programmed cell death, and DNA repair,among other subjects. The second edition captures these and other advances, and broadens its scope to address the experimental science of toxicology. The first edition of Molecular Toxicology has become an indispensable resource for graduate students in molecular and biochemical toxicology courses,as well as academic researchers and industrial researchers in toxicology. Rigorously updated and revised, the new edition commands an unrivaled authority in the field of molecular toxicology.

Molecular Toxicology in Caenorhabditis elegans

Dayong Wang
Molecular Toxicology in Caenorhabditis elegans Book PDF

Author : Dayong Wang
Publisher : Springer
Page : 447 pages
File Size : 43,6 Mb
Release : 2019-01-24
Category : Medical
ISBN : 9789811336331

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Molecular Toxicology in Caenorhabditis elegans by Dayong Wang Pdf

This book will focus on the molecular basis of oxidative stress induced by toxicants or stresses and various molecular signalling pathways in regulating the toxicity of toxicants or stresses in Caenorhabditis elegans. It will also cover the discussion on the aspects of response signals, G-protein coupled receptors and ion channels, specific molecular signals, and epigenetic signals involved in the regulation of toxicity from toxicants or stresses. The molecular basis for adaptive response for transgenerational toxicity of environmental toxicants or stresses will be further discussed. Nematode Caenorhabditis elegans is a classic model animal with well-described genetic and developmental backgrounds based on the study of life science, and has been further successfully and widely used in both toxicity assessment and toxicological study of various environmental toxicants or stresses. Based on related available data, this book aims at providing a systematic understanding of the knowledge system of molecular toxicology in C. elegans.

Molecular Toxicology

Nick Plant
Molecular Toxicology Book PDF

Author : Nick Plant
Publisher : Taylor & Francis
Page : 164 pages
File Size : 48,9 Mb
Release : 2021-02-26
Category : Science
ISBN : 9781000150216

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Molecular Toxicology by Nick Plant Pdf

Molecular Toxicology is a concise introduction to the subject, taking the reader through the theoretical principles of toxicology followed by specific examples. In the first section, the concepts behind possible mechanisms of toxicity are described (e.g. the specific enzyme or receptor system) using examples where appropriate. Following this a series of examples are used to show the extension of concept into the real world, in an organ specific manner. The book concludes with a section outlining toxicity assessment methods, where the impact of molecular biology is having a considerable impact, including DNA microarrays, proteomics and bioinformatics.

PCR Protocols in Molecular Toxicology

John P. Vanden Heuvel
PCR Protocols in Molecular Toxicology Book PDF

Author : John P. Vanden Heuvel
Publisher : CRC Press
Page : 258 pages
File Size : 46,5 Mb
Release : 2019-05-07
Category : Medical
ISBN : 1439805806

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PCR Protocols in Molecular Toxicology by John P. Vanden Heuvel Pdf

Molecular toxicology is an emerging discipline that utilizes molecular and cell biology to understand how drugs and chemicals result in their unwanted effects. PCR Protocols in Molecular Toxicology is a practical guide to the use of polymerase chain reaction (PCR) to help examine, on a molecular and cellular level, how toxic responses are manifested. It offers a basic understanding of PCR and its optimization, as well as describing specific, high-impact areas of molecular toxicology and recent advances. The following techniques are described in detail: Quantitative reverse transcriptase PCR and methods to examine gene expression Differential display cloning Cloning and library screening by PCR Genotype and polymorphism analysis of drug and toxicant metabolizing enzymes Basic, non-PCR based molecular biology methods PCR Protocols in Molecular Toxicology will aid both novices and experienced PCR practitioners in using PCR to its fullest potential.

Molecular, Clinical and Environmental Toxicology

Andreas Luch
Molecular Clinical and Environmental Toxicology Book PDF

Author : Andreas Luch
Publisher : Springer Science & Business Media
Page : 620 pages
File Size : 42,7 Mb
Release : 2010-03-01
Category : Medical
ISBN : 9783764383381

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Molecular, Clinical and Environmental Toxicology by Andreas Luch Pdf

Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Molecular, Clinical and Environmental Toxicology

Andreas Luch
Molecular Clinical and Environmental Toxicology Book PDF

Author : Andreas Luch
Publisher : Springer Science & Business Media
Page : 580 pages
File Size : 49,8 Mb
Release : 2012-06-07
Category : Medical
ISBN : 9783764383404

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Molecular, Clinical and Environmental Toxicology by Andreas Luch Pdf

Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Mechanistic Toxicology

Urs A. Boelsterli
Mechanistic Toxicology Book PDF

Author : Urs A. Boelsterli
Publisher : CRC Press
Page : 424 pages
File Size : 41,7 Mb
Release : 2007-03-23
Category : Medical
ISBN : 0849372720

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Mechanistic Toxicology by Urs A. Boelsterli Pdf

A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology

Advances in Molecular Toxicology

Anonim
Advances in Molecular Toxicology Book PDF

Author : Anonim
Publisher : Elsevier
Page : 0 pages
File Size : 55,6 Mb
Release : 2018-10-30
Category : Medical
ISBN : 0444638423

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Advances in Molecular Toxicology by Anonim Pdf

Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of progress on the molecular level and on advances in technological approaches employed.

Molecular Toxicology

Nick Plant
Molecular Toxicology Book PDF

Author : Nick Plant
Publisher : Taylor & Francis
Page : 164 pages
File Size : 43,9 Mb
Release : 2021-02-27
Category : Science
ISBN : 9781000107005

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Molecular Toxicology by Nick Plant Pdf

Molecular Toxicology is a concise introduction to the subject, taking the reader through the theoretical principles of toxicology followed by specific examples. In the first section, the concepts behind possible mechanisms of toxicity are described (e.g. the specific enzyme or receptor system) using examples where appropriate. Following this a series of examples are used to show the extension of concept into the real world, in an organ specific manner. The book concludes with a section outlining toxicity assessment methods, where the impact of molecular biology is having a considerable impact, including DNA microarrays, proteomics and bioinformatics.

Molecular and Cellular Toxicology

Lesley Stanley
Molecular and Cellular Toxicology Book PDF

Author : Lesley Stanley
Publisher : John Wiley & Sons
Page : 471 pages
File Size : 49,5 Mb
Release : 2014-04-02
Category : Medical
ISBN : 9781118526019

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Molecular and Cellular Toxicology by Lesley Stanley Pdf

Toxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects. Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which takes advantage of the opportunities offered by modern developments in the life sciences, including new in vitro and in silico approaches, alternative whole organism (non-mammalian) models and the exploitation of ‘omics methods, high throughput screening (HTS) techniques and molecular imaging technologies. This concise, accessible introduction to the field includes the very latest concepts and methodologies. It provides MSc, PhD and final year undergraduate students in pharmacy, biomedical and life sciences, as well as individuals starting out in the cosmetics, consumer products, pharmaceutical and testing industries, with everything they need to know to get to grips with the fast moving field of toxicology and the current approaches used in the risk assessment of drugs and chemicals.

Molecular, Clinical and Environmental Toxicology

Andreas Luch
Molecular Clinical and Environmental Toxicology Book PDF

Author : Andreas Luch
Publisher : Springer Science & Business Media
Page : 470 pages
File Size : 42,9 Mb
Release : 2009-04-03
Category : Medical
ISBN : 9783764383367

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Molecular, Clinical and Environmental Toxicology by Andreas Luch Pdf

Molecular Toxicology is the first volume of a three-volume set Molecular, Clinical and Environmental Toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals in daily life. By providing intriguing insights far down to the molecular level, this work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health and engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

An Introduction to Interdisciplinary Toxicology

Carey N. Pope,Jing Liu
An Introduction to Interdisciplinary Toxicology Book PDF

Author : Carey N. Pope,Jing Liu
Publisher : Academic Press
Page : 644 pages
File Size : 42,6 Mb
Release : 2020-03-06
Category : Medical
ISBN : 9780128136027

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An Introduction to Interdisciplinary Toxicology by Carey N. Pope,Jing Liu Pdf

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity Includes a variety of perspectives to give a complete understanding of toxicology Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained

Biomarkers in Toxicology

Ramesh C. Gupta
Biomarkers in Toxicology Book PDF

Author : Ramesh C. Gupta
Publisher : Academic Press
Page : 1246 pages
File Size : 55,5 Mb
Release : 2019-02-13
Category : Medical
ISBN : 9780128146569

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Biomarkers in Toxicology by Ramesh C. Gupta Pdf

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Advances in Molecular Toxicology

James C. Fishbein,Jacqueline M. Heilman
Advances in Molecular Toxicology Book PDF

Author : James C. Fishbein,Jacqueline M. Heilman
Publisher : Academic Press
Page : 164 pages
File Size : 41,8 Mb
Release : 2019-10-12
Category : Medical
ISBN : 9780444642943

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Advances in Molecular Toxicology by James C. Fishbein,Jacqueline M. Heilman Pdf

Advances in Molecular Toxicology, Volume Thirteen, features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment, and produced by the human body, manifest themselves as toxins. The work not only documents these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events are also reviewed by leading experts in the field. Provides cutting-edge reviews by leading workers in the discipline Includes in-depth dissection of the molecular aspects that are of interest to a broad range of scientists, physicians and students in the allied disciplines Presents leading-edge applications of technological innovations in chemistry, biochemistry and molecular medicine