Mouse Heart

Author : Fleur Hitchcock
Publisher : Nosy Crow
Page : 237 pages
File Size : 49,9 Mb
Release : 2022-08-04
Category : Juvenile Fiction
ISBN : 9781788009478

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Mouse Heart by Fleur Hitchcock Pdf

This atmospheric thriller, full of daring stunts and sinister villains, is perfect escapism for 9+ readers. Mouse, a foundling, loves her pieced-together family at the Moth Theatre fiercely. When their leading man, Walter, is wrongly arrested for murder, Mouse swears she'll free him. But another member of the cast has a secret identity - as a ruthless killer. As Mouse's investigation leads her ever closer to their true, deadly nature, can she outwit them without losing everything she holds dear? A masterfully told adventure from the acclaimed author of The Boy Who Flew and Murder in Midwinter, Mouse Heart is ideal for fans of Philip Pullman, Katherine Rundell and Philip Reeve.

Author : Anonim
Publisher : Elsevier
Page : 829 pages
File Size : 48,7 Mb
Release : 2006-12-15
Category : Science
ISBN : 9780080469072

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The Mouse in Biomedical Research by Anonim Pdf

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse’s normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Author : Piper M. Treuting,Suzanne M. Dintzis,Charles W. Frevert,Denny Liggitt,Kathleen S. Montine
Publisher : Academic Press
Page : 475 pages
File Size : 53,5 Mb
Release : 2012
Category : Medical
ISBN : 9780123813619

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Comparative Anatomy and Histology by Piper M. Treuting,Suzanne M. Dintzis,Charles W. Frevert,Denny Liggitt,Kathleen S. Montine Pdf

1. Introduction -- 2. Phenotyping -- 3. Necropsy and histology -- 4. Mammary Gland -- 5. Skeletal System -- 6. Nose, sinus, pharynx and larynx -- 7. Oral cavity and teeth -- 8. Salivary glands -- 9. Respiratory -- 10. Cardiovascular -- 11. Upper GI -- 12. Lower GI -- 13. Liver and gallbladder -- 14. Pancreas -- 15. Endocrine System -- 16. Urinary System -- 17. Female Reproductive System -- 18. Male Reproductive System -- 19. Hematopoietic and Lymphoid Tissues -- 20. Nervous System -- 21. Special senses, eye -- 22. Special senses, ear -- 23. Skin and adnexa -- Index.

Author : Jacek Z. Kubiak
Publisher : Springer Science & Business Media
Page : 436 pages
File Size : 43,6 Mb
Release : 2012-08-23
Category : Science
ISBN : 9783642304064

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Mouse Development by Jacek Z. Kubiak Pdf

The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) and Matthew Kaufman. This book provides an overview of mouse development, spanning from oocytes before fertilization to the state-of-the-art description of embryonic and adult stem cells. The chapters, written by the leading specialists in the field, deal with the most recent discoveries in this extremely fast-developing area of research.

Author : Lisa Fiedler
Publisher : Simon and Schuster
Page : 51 pages
File Size : 40,8 Mb
Release : 2015-10-20
Category : Juvenile Fiction
ISBN : 9781481420921

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Return of the Forgotten by Lisa Fiedler Pdf

Althought Felina the cat queen is gone, the subway tunnels are still dangerous, not only because of Hopper's rogue brother Pup and his arachnid companion Hacklemesh, but also due to a secret Firren has been hiding that worries her more than the disappearance of her daughter, Hope. Includes a bonus story, ATLANTIA RISING: How it All Began.

Author : Brian D. Hoit,Richard A. Walsh
Publisher : Springer Science & Business Media
Page : 403 pages
File Size : 48,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461516538

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Cardiovascular Physiology in the Genetically Engineered Mouse by Brian D. Hoit,Richard A. Walsh Pdf

The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data. The need for a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is underscored not only by these rapid advances, but by the increasing numbers of scientists who have focussed their research on genetically engineered mice. It is the primary objective of this second edition to interpret critically the literature and to provide a framework for the enormous amount of information in this burgeoning field. As in the first edition, the monograph serves as a practical guide for the investigator interested in the functional methods used to characterize the murine cardiovascular phenotype. However, this guidebook is a more comprehensive text than its predecessor; although the major objectives enumerated in the first edition have not substantially changed, they have been refined in keeping with the increased sophistication of the molecular biologist, geneticist, and physiologist in each other's discipline. Each chapter has been expanded and updated, richly enhanced with original tables and figures, and in many cases, extensively rewritten. Eight chapters written by internationally recognized experts have been added; this represents a 43 % increase from the first edition.

Author : An Van Den Bergh
Publisher : Leuven University Press
Page : 152 pages
File Size : 51,6 Mb
Release : 2006-12
Category : Electronic
ISBN : 9058675815

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Cardiac Contractility & Ca2+ Handling in Mouse Models of Type II Diabetes by An Van Den Bergh Pdf

Author : Janet Rossant,Patrick T. Tam
Publisher : Gulf Professional Publishing
Page : 712 pages
File Size : 49,7 Mb
Release : 2002-03-21
Category : Science
ISBN : 0080537030

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Mouse Development by Janet Rossant,Patrick T. Tam Pdf

This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels *Extensive coverage of a wide range of developmental mutations of the mouse *Excellent benchmark illustrations of brain, craniofacial, gut and heart development *In-depth experiment-based assessment of concepts in mammalian development *Focus on models of specific relevance to human development *Comprehensive reference to key literature and electronic databases related to mouse development *High-quality full-color production

Author : Mary C. Peavey,Sarah K. Dotters-Katz
Publisher : CRC Press
Page : 187 pages
File Size : 42,6 Mb
Release : 2021-05-05
Category : Medical
ISBN : 9781351628563

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Ultrasound of Mouse Fetal Development and Human Correlates by Mary C. Peavey,Sarah K. Dotters-Katz Pdf

Fetal development in the mouse is routinely and increasingly utilized for advancing translational research and medical innovation for human obstetrical care. This is the first and only manual to provide necessary content on how this should be handled for accurate and effective data collection. Detailed descriptions and examples demonstrate how researchers and clinicians can use murine fetal and obstetrical data to improve future human applications in diseases such as infertility, recurrent pregnancy loss, intrauterine fetal growth restriction, placental insufficiency, and intrauterine fetal demise, as well as organ-specific developmental disease.

Author : Hans Hedrich
Publisher : Academic Press
Page : 869 pages
File Size : 55,6 Mb
Release : 2012-07-16
Category : Medical
ISBN : 9780123820082

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The Laboratory Mouse by Hans Hedrich Pdf

"Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse"--Provided by publisher.

Author : Henry L. Foster,J. David Small,James G. Fox
Publisher : Academic Press
Page : 464 pages
File Size : 52,8 Mb
Release : 2014-05-10
Category : Health & Fitness
ISBN : 9781483262765

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The Mouse in Biomedical Research by Henry L. Foster,J. David Small,James G. Fox Pdf

The Mouse in Biomedical Research, Volume III: Normative Biology, Immunology, and Husbandry focuses on the normative biology, immunology, and husbandry of laboratory mice. Topics covered range from gnotobiotics and gastrointestinal microflora to animal health surveillance and health delivery systems, along with environmental monitoring. The management and design of breeding and research facilities are also discussed. Comprised of 18 chapters, this volume begins with an overview of studies involving gnotobiotic mice, the induction of gnotobiosis, and microbiological testing of gnotobiotic animals. Maintenance of breeding colonies of gnotobiotic animals is also considered, together with the shipment of gnotobiotes and laboratory facilities for using gnotobiotes. The reader is then introduced to management and design of breeding and research facilities for gnotobiotic mice; practical factors associated with providing adequate nutrition for laboratory mice; and environmental and equipment monitoring. Subsequent chapters deal with the basic biology of the mouse, including anatomy, embryology, reproductive physiology, physiology, endocrinology, hematology, clinical biochemistry, and gastrointestinal microflora. The book also examines immunoglobulins and immunoglobulin genes; lymphocyte immunogenetics; immune response disorders; and biomethodology and surgical techniques. This monograph will be useful to biologists, immunologists, researchers, and others those who use mice in the laboratory or are concerned with the production and maintenance of colonies of mice.

Author : Richard Baldock,Jonathan Bard,Duncan Davidson,Gillian Morriss-Kay
Publisher : Academic Press
Page : 343 pages
File Size : 45,5 Mb
Release : 2015-09-23
Category : Science
ISBN : 9780128009130

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Kaufman’s Atlas of Mouse Development Supplement by Richard Baldock,Jonathan Bard,Duncan Davidson,Gillian Morriss-Kay Pdf

Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. Provides high-resolution images for best visualization of key developmental processes and structures Offers in-depth anatomy and morphological views of organ systems Written descriptions convey developmental origins of the organ systems

Author : José Marín-García
Publisher : Springer Science & Business Media
Page : 511 pages
File Size : 52,7 Mb
Release : 2011-06-21
Category : Medical
ISBN : 9781441994615

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Signaling in the Heart by José Marín-García Pdf

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.

Author : Lisa Fiedler
Publisher : Simon and Schuster
Page : 368 pages
File Size : 40,9 Mb
Release : 2015-03-17
Category : Juvenile Fiction
ISBN : 9781481420914

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Hopper's Destiny by Lisa Fiedler Pdf

A brave mouse attempts to rebuild a fallen empire in this second book of the epic animal adventure series set in the subway tunnels of Brooklyn, for “fans of Erin Hunter, Brian Jaques, and Kathryn Lasky” (School Library Journal). The battle to free Titus’s camps is over, and Hopper, Zucker, Firren, and their loyal followers are working to rebuild. But the tunnels are in a state of chaos, and without the sinister peace accord to protect the rodents, Queen Felina and her growing army of ferals is a greater threat than ever before. In the Mūs Village, Pinkie has led a coup and is now ruling with an iron paw. And Pup has become cold and defiant, a change that Hopper never saw coming. When exterminators raid the tunnels, Hopper is snatched away by the intruders and taken back up to the daylight world where he was born. Upland, Hopper makes new allies, and as he enjoys the sights and sounds of Brooklyn, he wonders if he will ever make it back into the tunnels to restore safety and prosperity, as foretold by La Rocha’s prophecy. But why should Hopper fulfill a destiny he never wanted in the first place? Learn more at Mouseheart.com!

Author : Cheryl L. Scudamore
Publisher : John Wiley & Sons
Page : 258 pages
File Size : 54,9 Mb
Release : 2014-02-10
Category : Medical
ISBN : 9781119941200

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A Practical Guide to the Histology of the Mouse by Cheryl L. Scudamore Pdf

A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues. This book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions. This will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology. Written by experienced pathologists and specifically tailored to the needs of scientists and histologists Full colour throughout Provides advice on sampling tissues, necropsy and recording data Includes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation