Multiple Myeloma And Other Plasma Cell Disorders

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Multiple Myeloma and Other Plasma Cell Neoplasms

Meletios A. Dimopoulos,Thierry Facon,Evangelos Terpos
Multiple Myeloma and Other Plasma Cell Neoplasms Book PDF

Author : Meletios A. Dimopoulos,Thierry Facon,Evangelos Terpos
Publisher : Springer
Page : 245 pages
File Size : 41,8 Mb
Release : 2018-02-16
Category : Medical
ISBN : 9783319255866

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Multiple Myeloma and Other Plasma Cell Neoplasms by Meletios A. Dimopoulos,Thierry Facon,Evangelos Terpos Pdf

This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.

Hematologic Malignancies: Multiple Myeloma and Related Plasma Cell Disorders

Morie A. Gertz,Philip R. Greipp
Hematologic Malignancies Multiple Myeloma and Related Plasma Cell Disorders Book PDF

Author : Morie A. Gertz,Philip R. Greipp
Publisher : Springer Science & Business Media
Page : 494 pages
File Size : 53,9 Mb
Release : 2003-11-24
Category : Medical
ISBN : 354000811X

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Hematologic Malignancies: Multiple Myeloma and Related Plasma Cell Disorders by Morie A. Gertz,Philip R. Greipp Pdf

This handbook provides up-to-date and comprehensive treatment of all plasma cell disorders, including both common and rare disorders. All disease aspects from pathogenesis to most recent therapy are covered. The text originates from the Mayo Clinic, the world's most experienced institution in plasma cell disorders. Comprehensive treatise on all plasma cell disorders from the gene level to treatment of emergencies Chapters are uniformly organized for easy data access All authors are important authorities in their field with extensive clinical experience

Multiple Myeloma

Morie A. Gertz,S. Vincent Rajkumar
Multiple Myeloma Book PDF

Author : Morie A. Gertz,S. Vincent Rajkumar
Publisher : Springer Science & Business Media
Page : 311 pages
File Size : 55,7 Mb
Release : 2013-10-01
Category : Medical
ISBN : 9781461485209

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Multiple Myeloma by Morie A. Gertz,S. Vincent Rajkumar Pdf

This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias

Karthik Ramasamy,Sagar Lonial
Fast Facts Multiple Myeloma and Plasma Cell Dyscrasias Book PDF

Author : Karthik Ramasamy,Sagar Lonial
Publisher : Karger Medical and Scientific Publishers
Page : 162 pages
File Size : 44,9 Mb
Release : 2017-01-09
Category : Medical
ISBN : 9781910797334

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Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias by Karthik Ramasamy,Sagar Lonial Pdf

Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care

Allogeneic Stem Cell Transplantation

Hillard M. Lazarus,Mary J. Laughlin
Allogeneic Stem Cell Transplantation Book PDF

Author : Hillard M. Lazarus,Mary J. Laughlin
Publisher : Springer Science & Business Media
Page : 881 pages
File Size : 51,7 Mb
Release : 2010-03-02
Category : Medical
ISBN : 9781597454780

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Allogeneic Stem Cell Transplantation by Hillard M. Lazarus,Mary J. Laughlin Pdf

Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Multiple Myeloma and Other Plasma Cell Disorders

Bhratri BHUSHAN,DM Bhratri Bhushan MD
Multiple Myeloma and Other Plasma Cell Disorders Book PDF

Author : Bhratri BHUSHAN,DM Bhratri Bhushan MD
Publisher : Unknown
Page : 136 pages
File Size : 49,7 Mb
Release : 2019-05-22
Category : Electronic
ISBN : 109969342X

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Multiple Myeloma and Other Plasma Cell Disorders by Bhratri BHUSHAN,DM Bhratri Bhushan MD Pdf

Multiple myeloma accounts for 1 to 2 percent of all human cancers and around 15 percent of all hematologic malignancies. The premalignant condition leading to this disorder, monoclonal gammopathy of undetermined significance is found in 3 percent of the population above 50 years of age and progresses to multiple myeloma and other dyscrasias of plasma cells at a rate of 1 percent per year. So, not only the incidence and prevalence of these disorders is high, the science of management of myeloma and other plasma cell dyscrasias has become exceedingly complex with incorporation of genetic studies in the mainstream diagnostic and treatment decision making algorithms; as well as refinement of response assessment criteria, not to mention the bewildering array of treatment choices available, new therapies continually being added to the armamentarium and paradigm shift in established practices like hematopoietic stem cell transplantation. This book encompasses the topics of multiple myeloma, monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, plasma cell leukemia, mixed cryoglobulinemia syndrome, the heavy chain diseases, POEMS syndrome and amyloidosis and aims at updating and refreshing the knowledge of medical professionals as well as an easy read for non-professionals, to familiarize themselves with the concepts of plasma cell dyscrasias and thus empowering informed decision making.

Pathology of Bone and Joint Disorders Print and Online Bundle

Edward F. McCarthy,Frank J. Frassica
Pathology of Bone and Joint Disorders Print and Online Bundle Book PDF

Author : Edward F. McCarthy,Frank J. Frassica
Publisher : Cambridge University Press
Page : 385 pages
File Size : 44,8 Mb
Release : 2014-11-20
Category : Medical
ISBN : 9781107041233

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Pathology of Bone and Joint Disorders Print and Online Bundle by Edward F. McCarthy,Frank J. Frassica Pdf

Fully updated new edition covering all aspects of bone and joint diseases in one easily readable volume. Color illustrations throughout.

The Saint-Chopra Guide to Inpatient Medicine

Sanjay Saint,Vineet Chopra
The Saint Chopra Guide to Inpatient Medicine Book PDF

Author : Sanjay Saint,Vineet Chopra
Publisher : Oxford University Press, USA
Page : 609 pages
File Size : 51,5 Mb
Release : 2018
Category : Medical
ISBN : 9780190862800

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The Saint-Chopra Guide to Inpatient Medicine by Sanjay Saint,Vineet Chopra Pdf

Preceded by: Clinical clerkship in inpatient medicine / Sanjay Saint. 3rd ed. c2010.

Morphology of Blood Disorders

Giuseppe d'Onofrio,Gina Zini
Morphology of Blood Disorders Book PDF

Author : Giuseppe d'Onofrio,Gina Zini
Publisher : John Wiley & Sons
Page : 805 pages
File Size : 45,7 Mb
Release : 2014-12-03
Category : Medical
ISBN : 9781118442609

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Morphology of Blood Disorders by Giuseppe d'Onofrio,Gina Zini Pdf

Morphology of Blood Disorders, 2nd edition is an outstanding atlas with over 800 high-quality digital images, covering the whole spectrum of blood and bone marrow morphology, with particular emphasis on malignant haematology. Originally written in the Italian language by two world leaders in the field, the book has been expertly translated by the renowned haematologist and teacher, Barbara Bain. This book explores the major topics of haematological pathology, blending classical teaching with up-to-date WHO classification and terminology. Each image in this book is derived from material obtained for diagnostic purposes from patients with serious haematological conditions. Morphological details are supplemented by detailed descriptions of the output and role of automated instruments in disorders of the blood. Morphology of Blood Disorders, 2nd edition is an essential reference source for diagnosis in the haematology laboratory, designed to be the go-to guide for anyone with an interest in blood cell morphology.

Myeloma Therapy

Sagar Lonial
Myeloma Therapy Book PDF

Author : Sagar Lonial
Publisher : Springer Science & Business Media
Page : 674 pages
File Size : 52,6 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9781597455640

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Myeloma Therapy by Sagar Lonial Pdf

Therapeutic options for patients with myeloma have dramatically changed over the past 10 years. Beginning with the advances in therapy resulting from the use of high-dose therapy and autologous bone marrow or stem cell tra- plant, we have more than doubled the median survival for patients as a whole, and have now have a wealth of different biology -based treatment approaches for our patients in all disease stages. This book represents state-of-the-art information from many of the leaders in the plasma cell disorders world. Sections focusing on disease pathogenesis and biology, chemotherapy-based approaches, immune -based therapies, currently approved novel agents, developing targets, supportive care, and other plasma cell disorders provides a comprehensive collection and an excellent resource in this time of rapid change in clinical and preclinical disease knowledge. It is important to realize that these changes did not occur in a vacuum. Partnerships between academic institutions, the pharmaceutical industry, patient advocacy groups, the National Cancer Institute, community onco- gists, and ultimately our patients worked closely together to realize these advances, and to effect the radical changes in therapy we have witnessed over the past few years. This book would not have been possible without contri- tions from each of the gifted scientists and clinicians who worked tirelessly to prepare their individual chapters all the while maintaining commitment to the scientific and clinical mission of advancing care.

Multiple Myeloma and Related Serum Protein Disorders

Neil S. Harris, MD,William E. Winter
Multiple Myeloma and Related Serum Protein Disorders Book PDF

Author : Neil S. Harris, MD,William E. Winter
Publisher : Demos Medical Publishing
Page : 163 pages
File Size : 42,8 Mb
Release : 2012-03-23
Category : Medical
ISBN : 9781933864754

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Multiple Myeloma and Related Serum Protein Disorders by Neil S. Harris, MD,William E. Winter Pdf

A practical guide to the clinical use of serum and urine electrophoresis and also includes coverage of immunofixation electrophoresis. These techniques are essential in the accurate identification of monoclonal gammopathies and the diagnosis of multiple myeloma and related disorders. Interpretation is often challenging even for the experienced practitioner. Throughout the book the emphasis is on indications and practical aspects of interpreting test results. Particular attention is paid to differentiating false negative and false positive test results. The text provides clear, practical discussions extensively supported by representative images to guide the reader to accurate identification of specimens.

Multiple Myeloma

Roman Hajek
Multiple Myeloma Book PDF

Author : Roman Hajek
Publisher : BoD – Books on Demand
Page : 338 pages
File Size : 41,9 Mb
Release : 2013-04-10
Category : Medical
ISBN : 9789535110835

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Multiple Myeloma by Roman Hajek Pdf

This book does not provide a comprehensive overview of Multiple Myeloma but a collection of chapters with in-depth information of distinct hot topics in the diagnostic, research and therapeutic fields. The dynamics of testing new drugs for multiple myeloma treatment in clinical trials is breathtaking. Scientific discoveries have uncovered complicated pathogenesis of multiple myeloma; complicated reactions to treatment lead to the creation of super cocktails. Curability of multiple myeloma is a question that is being discussed by the entire professional myeloma world. Improvement of prognosis is a fact which is most important from a patient's perspective. We believe that this book could be of interest to medical professionals specializing in hematooncology, researchers, as well as many others.

Update on Multiple Myeloma

Khalid Ahmed Al-Anazi
Update on Multiple Myeloma Book PDF

Author : Khalid Ahmed Al-Anazi
Publisher : Unknown
Page : 236 pages
File Size : 51,9 Mb
Release : 2019-02
Category : Neoplasms. Tumors. Oncology. Including cancer and carcinogens
ISBN : 9781789852172

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Update on Multiple Myeloma by Khalid Ahmed Al-Anazi Pdf

This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries.

Multiple Myeloma and Plasma Cell Dyscrasias

Karthik Ramasamy,Sagar Lonial
Multiple Myeloma and Plasma Cell Dyscrasias Book PDF

Author : Karthik Ramasamy,Sagar Lonial
Publisher : Health Press (NM)
Page : 0 pages
File Size : 40,7 Mb
Release : 2015-08-03
Category : Multiple myeloma
ISBN : 1908541954

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Multiple Myeloma and Plasma Cell Dyscrasias by Karthik Ramasamy,Sagar Lonial Pdf

Multiple Myeloma accounts for approximately 0.8% of cancers worldwide, with about 114 000 new cases each year. Rapid progress is being made in the development of new treatments and, although myeloma is incurable at present, survival has almost tripled over the past 10 years and it is now projected that a third of patients will survive more than 10 years after diagnosis. Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias emphasizes the importance of early diagnosis for a favourable outcome, covers the ever-increasing role of genetics in diagnosis and treatment, and discusses new and gold-standard treatments. A chapter on supportive care also features and briefs the healthcare professional on long-term outcomes and quality of life issues. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of myeloma and other plasma cell dyscrasias, from bench to bedside, putting the pathogenesis, diagnosis and treatment of these disorders in the context of daily clinical practice.

Textbook of Uncommon Cancer

Derek Raghavan,Manmeet S. Ahluwalia,Charles D. Blanke,Jubilee Brown,Edward S. Kim,Gregory H. Reaman,Mikkael A. Sekeres
Textbook of Uncommon Cancer Book PDF

Author : Derek Raghavan,Manmeet S. Ahluwalia,Charles D. Blanke,Jubilee Brown,Edward S. Kim,Gregory H. Reaman,Mikkael A. Sekeres
Publisher : John Wiley & Sons
Page : 1296 pages
File Size : 52,6 Mb
Release : 2017-03-03
Category : Medical
ISBN : 9781119196211

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Textbook of Uncommon Cancer by Derek Raghavan,Manmeet S. Ahluwalia,Charles D. Blanke,Jubilee Brown,Edward S. Kim,Gregory H. Reaman,Mikkael A. Sekeres Pdf

The fifth edition of the only comprehensive text dealing exclusively with rare or infrequently encountered malignancies in adults and children is an essential resource for any clinical oncologist. Encompasses all the information needed to diagnose and manage uncommon cancers, an area where advice and guidance is typically scarce Fully revised with new material and an evidence-based, teach-by-example approach Provides insight on real-world decision making in the clinical setting Edited and authored by a highly experienced and senior team of medical oncologists, radiation oncologists, and other specialists, giving a balanced and complete overview Extensively illustrated in full color throughout, including heat maps to show gene expression