Nanoparticle Toxicity And Compatibility

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Nanoparticle Toxicity and Compatibility

Jorddy N. Cruz
Nanoparticle Toxicity and Compatibility Book PDF

Author : Jorddy N. Cruz
Publisher : Materials Research Forum LLC
Page : 272 pages
File Size : 47,5 Mb
Release : 2024-03-15
Category : Technology & Engineering
ISBN : 9781644902998

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Nanoparticle Toxicity and Compatibility by Jorddy N. Cruz Pdf

The book focuses on the interplay between nanoparticles and biological systems. Topics covered include the synthesis, characterization, and application of nanomaterials in tissue engineering; the interaction of nanoparticles with macromolecules; biomedical and food science applications; the cardiovascular toxicity of nanoparticles; colon targeted nano drug delivery systems; the biocompatibility and immunogenicity of nanoparticles; plasmon-enhanced biosensing applications; strategies for enhancing the biocompatibility of nanoparticles; the environmental impact of nanoparticles; as well as the intricate dynamics between nanoparticles and living organisms. Keywords: Tissue Engineering, Cardiovascular Toxicity, Drug Delivery Systems, Plasmon-Enhanced Biosensing, Biocompatibility of Nanoparticles, Ecotoxicology of Nanoparticles, Bioinspired Nanosynthesis, Hepatotoxicity, Nano Drug Delivery, Nanofabrication, Nanorobots, Plasmonics, Probiotics, Protein.

Nanoparticle Toxicity and Compatibility

Jorddy N. Cruz
Nanoparticle Toxicity and Compatibility Book PDF

Author : Jorddy N. Cruz
Publisher : Materials Research Forum LLC
Page : 272 pages
File Size : 54,9 Mb
Release : 2024-03-15
Category : Technology & Engineering
ISBN : 9781644902981

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Nanoparticle Toxicity and Compatibility by Jorddy N. Cruz Pdf

The book focuses on the interplay between nanoparticles and biological systems. Topics covered include the synthesis, characterization, and application of nanomaterials in tissue engineering; the interaction of nanoparticles with macromolecules; biomedical and food science applications; the cardiovascular toxicity of nanoparticles; colon targeted nano drug delivery systems; the biocompatibility and immunogenicity of nanoparticles; plasmon-enhanced biosensing applications; strategies for enhancing the biocompatibility of nanoparticles; the environmental impact of nanoparticles; as well as the intricate dynamics between nanoparticles and living organisms. Keywords: Tissue Engineering, Cardiovascular Toxicity, Drug Delivery Systems, Plasmon-Enhanced Biosensing, Biocompatibility of Nanoparticles, Ecotoxicology of Nanoparticles, Bioinspired Nanosynthesis, Hepatotoxicity, Nano Drug Delivery, Nanofabrication, Nanorobots, Plasmonics, Probiotics, Protein.

Modelling the Toxicity of Nanoparticles

Lang Tran,Miguel A. Bañares,Robert Rallo
Modelling the Toxicity of Nanoparticles Book PDF

Author : Lang Tran,Miguel A. Bañares,Robert Rallo
Publisher : Springer
Page : 360 pages
File Size : 52,7 Mb
Release : 2017-02-06
Category : Medical
ISBN : 9783319477541

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Modelling the Toxicity of Nanoparticles by Lang Tran,Miguel A. Bañares,Robert Rallo Pdf

In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.

Unraveling the Safety Profile of Nanoscale Particles and Materials

Andreia Ferreira de Castro Gomes,Marisa P. Sárria
Unraveling the Safety Profile of Nanoscale Particles and Materials Book PDF

Author : Andreia Ferreira de Castro Gomes,Marisa P. Sárria
Publisher : BoD – Books on Demand
Page : 174 pages
File Size : 44,9 Mb
Release : 2018-03-21
Category : Technology & Engineering
ISBN : 9789535139393

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Unraveling the Safety Profile of Nanoscale Particles and Materials by Andreia Ferreira de Castro Gomes,Marisa P. Sárria Pdf

As nanomaterials become increasingly present in our daily lives, pertinent questions regarding their safety arise. Nanomaterial risk assessment, as in other areas, directs much of the effort worldwide in defining guidelines that may be translated into national or international directives. Nanomaterials encompass different entities, from nanoparticles to nanostructured materials, with specific effects over cells, tissues, organisms and ecosystems depending on their biophysical characteristics. Such interactions will directly affect the impact of novel nanotechnologies. This book aims to provide the reader with a comprehensive overview of the current state of the art in nanotoxicology, featuring the most important developments and critical issues regarding the use of and exposure to nanoparticles.

Gold Nanoparticles in Biomedical Applications

Lev Dykman,Nikolai Khlebtsov
Gold Nanoparticles in Biomedical Applications Book PDF

Author : Lev Dykman,Nikolai Khlebtsov
Publisher : CRC Press
Page : 430 pages
File Size : 49,5 Mb
Release : 2017-12-12
Category : Medical
ISBN : 9781351360470

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Gold Nanoparticles in Biomedical Applications by Lev Dykman,Nikolai Khlebtsov Pdf

This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.

Fundamentals of Drug Delivery

Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang
Fundamentals of Drug Delivery Book PDF

Author : Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang
Publisher : John Wiley & Sons
Page : 580 pages
File Size : 48,5 Mb
Release : 2021-10-12
Category : Medical
ISBN : 9781119769606

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Fundamentals of Drug Delivery by Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang Pdf

A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Anisotropic and Shape-Selective Nanomaterials

Simona E. Hunyadi Murph,George K. Larsen,Kaitlin J. Coopersmith
Anisotropic and Shape Selective Nanomaterials Book PDF

Author : Simona E. Hunyadi Murph,George K. Larsen,Kaitlin J. Coopersmith
Publisher : Springer
Page : 470 pages
File Size : 43,6 Mb
Release : 2017-07-14
Category : Science
ISBN : 9783319596624

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Anisotropic and Shape-Selective Nanomaterials by Simona E. Hunyadi Murph,George K. Larsen,Kaitlin J. Coopersmith Pdf

This book reviews recent advances in the synthesis, characterization, and physico-chemical properties of anisotropic nanomaterials. It highlights various emerging applications of nanomaterials, including sensing and imaging, (bio)medical applications, environmental protection, plasmonics, catalysis, and energy. It provides an excellent and comprehensive overview of the effect that morphology and nanometric dimension has on the physico-chemical properties of various materials and how this leads to novel applications.

Silicon and Siliceous Structures in Biological Systems

T.L. Simpson,B.E. Volcani
Silicon and Siliceous Structures in Biological Systems Book PDF

Author : T.L. Simpson,B.E. Volcani
Publisher : Springer Science & Business Media
Page : 589 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461259442

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Silicon and Siliceous Structures in Biological Systems by T.L. Simpson,B.E. Volcani Pdf

The publication of this book was undertaken with two purposes in view: to bring together informatian on the deposition by living organ isms of unique skeletal structures composed of amorphous silica, and to review recent data on the involvement of silicon in physiological and biochemical processes. Although widely varying viewpoints are represented, all the contributors are very interested in the events in volved in the formatian of siliceaus structures and their function. Data presented deal with these questions in a variety of plant and animal systems, and at levels ranging from the evolutionary to the biochemical and ultrastructural. Innovations in electron microscopy and, indeed, the advent of electron microscopy itself, have stimulated many ultra structural studies of silica deposition, work which has deepened and widened the interest in those organisms which routinely produce "glassy skeletons. " The question of how silicon participates in biological systems in volves a spectrum of fields that indudes the chemistry of silicon per se, its biogeochemistry, biochemistry, ecology, and so forth. In this book, however, attention is focused up on the biological aspects of silicon and siliceous structures, with emphasis on the evolutian, phylogeny, morphology, and distribution of siliceaus structures, on the cellular as peets of silica deposition, and on the physiological and biochemical roles of silicon. This volume represents the first compilatian of such data. Because such a variety of subjects and fields are covered, the reader will have to glean for himself some of the comparative aspects of the data.

Toxicity of Nanomaterials

Suresh C. Pillai,Yvonne Lang
Toxicity of Nanomaterials Book PDF

Author : Suresh C. Pillai,Yvonne Lang
Publisher : CRC Press
Page : 246 pages
File Size : 54,6 Mb
Release : 2021-03-31
Category : Nanostructured materials
ISBN : 0367779757

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Toxicity of Nanomaterials by Suresh C. Pillai,Yvonne Lang Pdf

This book, edited by two leading experts in nanotoxicology with contributions from a global team of specialists, provides a comprehensive overview of the risks and environmental and health impacts assosciated with the toxicology of nanomaterials.

Plenty of Room for Biology at the Bottom

Ehud Gazit
Plenty of Room for Biology at the Bottom Book PDF

Author : Ehud Gazit
Publisher : World Scientific
Page : 214 pages
File Size : 45,5 Mb
Release : 2013
Category : Science
ISBN : 9781848169319

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Plenty of Room for Biology at the Bottom by Ehud Gazit Pdf

This expanded and updated edition of the 2007 version introduces readers from various backgrounds to the rapidly growing interface between biology and nanotechnology. It intellectually integrates concepts, applications, and outlooks from these major scientific fields and presents them to readers from diverse backgrounds in a comprehensive and didactic manner.Written by two leading nanobiologists actively involved at the forefront of the field both as researchers and educators, this book takes the reader from the fundamentals of nanobiology to the most advanced applications.The book fulfils a unique niche: to address not only students, but also scientists who are eager (and nowadays obliged) to learn about other state-of-the-art disciplines. The book is written in such a way as to be accessible to biologists, chemists, and physicists with no background in nanotechnology (for example biologists who are interested in inorganic nanostructures or physicists who would like to learn about biological assemblies and applications thereof). It is reader-friendly and will appeal to a wide audience not only in academia but also in the industry and anyone interested in learning more about nanobiotechnology.

Nanoparticles and the Immune System

Diana Boraschi,Albert Duschl
Nanoparticles and the Immune System Book PDF

Author : Diana Boraschi,Albert Duschl
Publisher : Academic Press
Page : 139 pages
File Size : 54,9 Mb
Release : 2013-11-29
Category : Medical
ISBN : 9780124079212

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Nanoparticles and the Immune System by Diana Boraschi,Albert Duschl Pdf

Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage for amplifying immune responses in certain diseases or preventive strategies (e.g. vaccination). Identifies endpoints relevant for assessing hazardous situations, evaluating the impact on immunologically frail populations and how to gauge chronic/cumulative effects Raises the awareness of the importance of knowing the effects of the new nanomaterials on our immune system

Biomedical Applications of Nanoparticles

Alexandru Mihai Grumezescu
Biomedical Applications of Nanoparticles Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 530 pages
File Size : 50,9 Mb
Release : 2019-02-28
Category : Medical
ISBN : 9780128166307

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Biomedical Applications of Nanoparticles by Alexandru Mihai Grumezescu Pdf

Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view Presents the recent progress related to nanotherapeutics in the oral cavity Provides the recent progress in the field of biomedical nanoparticles

Optical Methods and Instrumentation in Brain Imaging and Therapy

Steen J. Madsen
Optical Methods and Instrumentation in Brain Imaging and Therapy Book PDF

Author : Steen J. Madsen
Publisher : Springer Science & Business Media
Page : 284 pages
File Size : 55,6 Mb
Release : 2012-11-13
Category : Science
ISBN : 9781461449782

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Optical Methods and Instrumentation in Brain Imaging and Therapy by Steen J. Madsen Pdf

This book provides a comprehensive up-to-date review of optical approaches used in brain imaging and therapy. It covers a variety of imaging approaches including diffuse optical imaging, laser speckle imaging, photoacoustic imaging and optical coherence tomography. A number of laser-based therapeutic techniques are reviewed, including photodynamic therapy, fluorescence guided resection and photothermal therapy. Fundamental principles and instrumentation are discussed for each imaging and therapeutic approach.

Pharmaceutical Nanotechnology, 2 Volumes

Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde
Pharmaceutical Nanotechnology 2 Volumes Book PDF

Author : Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde
Publisher : John Wiley & Sons
Page : 804 pages
File Size : 47,6 Mb
Release : 2017-06-19
Category : Technology & Engineering
ISBN : 9783527340545

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Pharmaceutical Nanotechnology, 2 Volumes by Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde Pdf

With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!

Cellular and Molecular Toxicology of Nanoparticles

Quaiser Saquib,Mohammad Faisal,Abdulaziz A. Al-Khedhairy,Abdulrahman A. Alatar
Cellular and Molecular Toxicology of Nanoparticles Book PDF

Author : Quaiser Saquib,Mohammad Faisal,Abdulaziz A. Al-Khedhairy,Abdulrahman A. Alatar
Publisher : Springer
Page : 0 pages
File Size : 49,8 Mb
Release : 2019-01-26
Category : Science
ISBN : 3030101509

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Cellular and Molecular Toxicology of Nanoparticles by Quaiser Saquib,Mohammad Faisal,Abdulaziz A. Al-Khedhairy,Abdulrahman A. Alatar Pdf

This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”. The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.