Natural Products As Anticancer Agents

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Natural Products as Anticancer Agents

Bimal Krishna Banik,Aparna Das
Natural Products as Anticancer Agents Book PDF

Author : Bimal Krishna Banik,Aparna Das
Publisher : Elsevier
Page : 444 pages
File Size : 41,6 Mb
Release : 2023-11-21
Category : Science
ISBN : 9780323997119

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Natural Products as Anticancer Agents by Bimal Krishna Banik,Aparna Das Pdf

Natural Products as Anticancer Agents introduces the different types of natural products that have been used for cancer treatment. Divided into four parts, covering anticancer agents derived from terrestrial plants, anticancer agents derived from the marine environment, and anticancer agents derived from microorganisms, as well as evaluation of new anticancer agents, each part includes discussion of the properties, synthesis/extraction, storage, mechanism of action, and usage of the molecules. Discussion of the future prospects in anticancer natural products—including several new trends and an indication of where research in this area is likely to go in the future—is also included. Assists in the identification of risk factors associated with the drug development process Includes process diagrams detailing the procedure for the isolation and purification of molecules Covers cost-effective green approaches in the development of anticancer drugs

Anticancer Agents from Natural Products

Gordon M. Cragg,David G. I. Kingston,David J. Newman
Anticancer Agents from Natural Products Book PDF

Author : Gordon M. Cragg,David G. I. Kingston,David J. Newman
Publisher : CRC Press
Page : 610 pages
File Size : 41,6 Mb
Release : 2005-06-13
Category : Medical
ISBN : 9781420039658

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Anticancer Agents from Natural Products by Gordon M. Cragg,David G. I. Kingston,David J. Newman Pdf

Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen

Anticancer Agents from Natural Products, Second Edition

Gordon M. Cragg,David G. I. Kingston,David J. Newman
Anticancer Agents from Natural Products Second Edition Book PDF

Author : Gordon M. Cragg,David G. I. Kingston,David J. Newman
Publisher : CRC Press
Page : 786 pages
File Size : 49,7 Mb
Release : 2011-10-10
Category : Science
ISBN : 9781439813829

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Anticancer Agents from Natural Products, Second Edition by Gordon M. Cragg,David G. I. Kingston,David J. Newman Pdf

The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the: History of each covered drug—a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery Important biosynthetic approaches to "unnatural" natural products Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis—enabled by historic advances in methodology—has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future. Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.

Natural Products and Cancer Drug Discovery

Frank E. Koehn
Natural Products and Cancer Drug Discovery Book PDF

Author : Frank E. Koehn
Publisher : Springer Science & Business Media
Page : 248 pages
File Size : 51,9 Mb
Release : 2012-11-09
Category : Medical
ISBN : 9781461446545

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Natural Products and Cancer Drug Discovery by Frank E. Koehn Pdf

This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools for new target generation , new approaches to cancer drug discovery through natural products based lead generation, and enabling technologies which leverage the unique attributes of natural products.

New Approaches to Natural Anticancer Drugs

Soodabeh Saeidnia
New Approaches to Natural Anticancer Drugs Book PDF

Author : Soodabeh Saeidnia
Publisher : Springer
Page : 117 pages
File Size : 45,9 Mb
Release : 2015-02-05
Category : Medical
ISBN : 9783319140278

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New Approaches to Natural Anticancer Drugs by Soodabeh Saeidnia Pdf

This book provides an up-to-date review of recently identified natural anti-tumor compounds from various natural origins including plants, fungi, endophytic fungi and marine organisms. It also includes discussion of new areas such as biotechnology and nanoparticles. Chapters explain the challenges and developments in anti-cancer drug discovery approaches, traditional remedies for prevention and treatment of cancer, marine-derived anti-cancer compounds, and antibiotics used as anti-cancer agents, as well as different classes of terpenoids and carbohydrates, which have been the subject of discussion in this field as efficient anti-cancer candidates. This book will be a concise guide for researchers in the field of pharmaceutical sciences, students and residents in pharmacy and medicine as well as those researching phytochemistry and natural products.

Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach

Motamarri Venkata Naga Lalitha Chaitanya,Galvina Pereira,Heyam Saad Ali
Alternative Remedies and Natural Products for Cancer Therapy An Integrative Approach Book PDF

Author : Motamarri Venkata Naga Lalitha Chaitanya,Galvina Pereira,Heyam Saad Ali
Publisher : Bentham Science Publishers
Page : 325 pages
File Size : 52,7 Mb
Release : 2023-11-02
Category : Medical
ISBN : 9789815124705

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Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach by Motamarri Venkata Naga Lalitha Chaitanya,Galvina Pereira,Heyam Saad Ali Pdf

This book provides a holistic view of natural products and remedies that have been used to treat cancer. The editors aim to educate readers about the importance of the translational role of natural products in cancer treatment by compiling 14 chapters. The book emphasizes an integrative approach to the topic by blending traditional knowledge that supports alternative therapies with the science of phytochemicals and drug discovery technologies as a means to manage the disease. Key topics include alternative therapies (such as aromatherapy and immune boosting herbal medications), cytotoxic and anti-cancer phytochemicals, drug delivery and discovery technologies (including high-throughput screening) and some drug targets of interest for cancer treatment (such as topoisomerases and caspases). Readers will be able to learn about natural sources of ant-cancer compounds, and the methods used by research and development experts in pharmaceutical and nutraceutical industries to isolate and formulate these compounds. This book will be a handy resource for a wide range of readers. This includes researchers, traditional medical practitioners, PG students, Ph.D. scholars and general readers to understand the role of natural products in cancer treatment. key features - Explains the importance of alternative therapies in the management of cancer - Emphasizes the ethnopharmacological approaches to cancer - Explores natural anticancer drug libraries - Discusses the role of modern cancer targets and the importance of in-silico tools in anticancer drug discovery - Addresses modern drug discovery tools and drug delivery technologies concerning their applications in cancer treatment. - Includes references for further reading

Natural Products and Cancer Drug Discovery

Farid A. Badria
Natural Products and Cancer Drug Discovery Book PDF

Author : Farid A. Badria
Publisher : BoD – Books on Demand
Page : 318 pages
File Size : 49,9 Mb
Release : 2017-07-05
Category : Medical
ISBN : 9789535133131

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Natural Products and Cancer Drug Discovery by Farid A. Badria Pdf

This book, Natural Products and Cancer Drug Discovery, is written by leading experts in natural products in cancer therapy. The first two sections describe new applications of common herbs and foods for treatment of cancer. Section 3 deals with the development of new chemotherapeutics from Cannabis and endophytic fungi. Section 4 presented formulations of natural products for treatment of malignant melanoma. Made-to-order anticancer therapy from natural products using computational and tissue engineering approaches is addressed in the fifth section. It is our hope that this book may motivate readers to approach the evidence of anticancer natural products with an open mind and thereby spark an interest in making further contributions to the cancer treatment efforts.

Natural Products for Cancer Prevention and Therapy

Anupam Bishayee,Mukerrem Betul Yerer-Aycan
Natural Products for Cancer Prevention and Therapy Book PDF

Author : Anupam Bishayee,Mukerrem Betul Yerer-Aycan
Publisher : MDPI
Page : 285 pages
File Size : 45,6 Mb
Release : 2018-11-07
Category : Electronic books
ISBN : 9783038973102

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Natural Products for Cancer Prevention and Therapy by Anupam Bishayee,Mukerrem Betul Yerer-Aycan Pdf

This book is a printed edition of the Special Issue "Natural Products for Cancer Prevention and Therapy" that was published in Nutrients

Discovery and Development of Anti-Breast Cancer Agents from Natural Products

Goutam Brahmachari
Discovery and Development of Anti Breast Cancer Agents from Natural Products Book PDF

Author : Goutam Brahmachari
Publisher : Elsevier
Page : 386 pages
File Size : 41,7 Mb
Release : 2021-06-24
Category : Science
ISBN : 9780128212783

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Discovery and Development of Anti-Breast Cancer Agents from Natural Products by Goutam Brahmachari Pdf

Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields. Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area. Highlights active agents from natural sources for development as novel anti-cancer agents Features contributions from active researchers and leading experts working in the field Includes foundational background information on both breast cancer mechanisms and natural product structures to support researchers from different disciplines

Anticancer Plants: Natural Products and Biotechnological Implements

Mohd Sayeed Akhtar,Mallappa Kumara Swamy
Anticancer Plants Natural Products and Biotechnological Implements Book PDF

Author : Mohd Sayeed Akhtar,Mallappa Kumara Swamy
Publisher : Springer
Page : 564 pages
File Size : 44,6 Mb
Release : 2018-07-02
Category : Science
ISBN : 9789811080647

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Anticancer Plants: Natural Products and Biotechnological Implements by Mohd Sayeed Akhtar,Mallappa Kumara Swamy Pdf

This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Anticancer Drug Discovery and Development: Natural Products and New Molecular Models

Frederick A. Valeriote,Thomas H. Corbett,Laurence H. Baker
Anticancer Drug Discovery and Development Natural Products and New Molecular Models Book PDF

Author : Frederick A. Valeriote,Thomas H. Corbett,Laurence H. Baker
Publisher : Springer Science & Business Media
Page : 289 pages
File Size : 45,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461526100

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Anticancer Drug Discovery and Development: Natural Products and New Molecular Models by Frederick A. Valeriote,Thomas H. Corbett,Laurence H. Baker Pdf

With the publication of these proceedings from the Second Drug Discovery and Development Symposium, this forum has become the main mechanism for bringing together the principal groups involved in both discovering and developing new approaches to the treatment of cancer. This Second Symposium emphasized the types of materials being discovered and their therapeutic activity. This is especially evident in the natural product discovery programs, where unique and active structures are being identified. The major contributors to the meeting were the investigators participating in the National Cooperative (Natural Products) Drug Discovery Groups [NC(NP)DDG]. These groups reflect an association among researchers at universities or cancer centers, pharmaceutical companies and the National Cancer Institute. Their sources of materials are varied, reflecting chemical inventories of pharmaceutical companies, organic synthetic compounds from the laboratory, cytotoxics as well as biologics and their hybrids, and natural products obtained from plants, marine organisms and microorganisms. The models employed in the discovery systems vary from broadly cellular based to specific enzymes to defined cellular functions. Each of them is believed important to the malignant state and will allow for the discovery of compounds which will have efficacy in cancer therapy. The goal of the participants is both to discover new anticancer agents and to develop them as efficiently as possible into clinically useful additions to treatment. Of importance is the fact that there are a number of promising leads which will soon be moving into the clinic thereby testing the effectiveness of this NC (NP) DDG approach.

Marine Natural Products as Anticancer Agents 2.0

Celso Alves,Marc Diederich
Marine Natural Products as Anticancer Agents 2 0 Book PDF

Author : Celso Alves,Marc Diederich
Publisher : Mdpi AG
Page : 0 pages
File Size : 52,8 Mb
Release : 2023-06-12
Category : Electronic
ISBN : 3036575685

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Marine Natural Products as Anticancer Agents 2.0 by Celso Alves,Marc Diederich Pdf

Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, "Marine Natural Products as Anticancer Agents 2.0", gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents.

Natural Products in Chemical Biology

Natanya Civjan
Natural Products in Chemical Biology Book PDF

Author : Natanya Civjan
Publisher : John Wiley & Sons
Page : 437 pages
File Size : 45,6 Mb
Release : 2012-07-03
Category : Science
ISBN : 9781118101179

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Natural Products in Chemical Biology by Natanya Civjan Pdf

Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.

Bioactive Natural Products for the Management of Cancer: from Bench to Bedside

Anil K. Sharma
Bioactive Natural Products for the Management of Cancer from Bench to Bedside Book PDF

Author : Anil K. Sharma
Publisher : Springer
Page : 218 pages
File Size : 40,7 Mb
Release : 2019-07-17
Category : Medical
ISBN : 9789811376078

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Bioactive Natural Products for the Management of Cancer: from Bench to Bedside by Anil K. Sharma Pdf

This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms. Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.

Cancer Drug Discovery

Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim
Cancer Drug Discovery Book PDF

Author : Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim
Publisher : Springer
Page : 276 pages
File Size : 51,5 Mb
Release : 2016-11-14
Category : Medical
ISBN : 9789402408447

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Cancer Drug Discovery by Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim Pdf

The reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs deeply influenced by the cell concept of cancer and future directions for the development of new anticancer drugs. First, this book documents the scientific progress in biological science over the last 70 years and the influence this progress had in cancer research. Summaries and charts of important discoveries complete this overview. Furthermore, this book outlines the process of anticancer drug development with a focus on the characteristic drug groups of each era, related to advancements of chemistry and biological sciences. This book also provides brief mechanism of action of drugs, illustrated by comprehensive timelines and conceptual cartoons. This book finally sums up the limitations of the current anticancer drug development and seeks new directions for anticancer drug discovery, considering under the systemic view of cancer.