Neuronal Plasticity And Memory Formation

Author : Federico Bermudez-Rattoni
Publisher : CRC Press
Page : 368 pages
File Size : 53,9 Mb
Release : 2007-04-17
Category : Science
ISBN : 1420008412

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Neural Plasticity and Memory by Federico Bermudez-Rattoni Pdf

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies. The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function. Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.

Author : Cosimo Ajmone Marsan,Hansjürgen Matthies
Publisher : Unknown
Page : 696 pages
File Size : 47,5 Mb
Release : 1982
Category : Memory
ISBN : UCAL:B4526022

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Neuronal Plasticity and Memory Formation by Cosimo Ajmone Marsan,Hansjürgen Matthies Pdf

Author : Christian Hölscher
Publisher : Cambridge University Press
Page : 508 pages
File Size : 41,8 Mb
Release : 2005-09-29
Category : Medical
ISBN : 052101803X

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Neuronal Mechanisms of Memory Formation by Christian Hölscher Pdf

Long-term potentiation (LTP) is the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and also fits the anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained regarding how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. Some of these studies have failed to find a correlation between the two forms of synaptic plasticity, signalling a need to discuss the concept of LTP and possible alternate processes that could fit the available data. This book presents a selection of ideas that range from supporters of the LTP theory to different novel concepts that have yet to be investigated. This volume will prepare the ground for research in this area in the new millennium.

Author : J. David Sweatt
Publisher : Elsevier
Page : 350 pages
File Size : 45,5 Mb
Release : 2003-11-18
Category : Psychology
ISBN : 0080521967

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Mechanisms of Memory by J. David Sweatt Pdf

This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms. * Presents a unified view of memory mechanisms from behavior to genes and drawing examples from many different brain regions, types of learning, and various animal model systems * Includes numerous practical examples for the new investigator on how to implement research program in the area of learning and memory * Provides a balanced treatment of the strengths and weaknesses in modern experimental design

Author : Alfredo Meneses
Publisher : Elsevier
Page : 180 pages
File Size : 41,6 Mb
Release : 2013-11-23
Category : Psychology
ISBN : 9780124167117

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Identification of Neural Markers Accompanying Memory by Alfredo Meneses Pdf

Identification of Neural Markers Accompanying Memory is a fresh and novel volume of memory study, providing up-to-date and comprehensive information for both students and researchers focused on the identification of neural markers accompanying memory. Contributions by experts in specific areas of memory study provide background on and definitions of memory, memory alterations, and the brain areas involved in memory and its related processes, such as consolidation, retrieval, forgetting, amnesia, and antiamnesiac effects. With coverage of the principal neurotransmitters related to memory, brain disorders presenting memory alterations, and available treatments—and with discussion of neural markers as new targets for the treatment of memory alterations—Identification of Neural Markers Accompanying Memory is a necessary and timely work for researchers in this growing field. Discusses the alterations of memory in diverse diseases Includes coverage from a basic introduction of memory investigation Reviews brain areas and neurotransmitters involved in memory Discusses behavioral models of memory Contains novel insights into the complexity of signaling and memory Includes the neuropharmacological and neurobiological bases of memory

Author : Akademie der Wissenschaften und der Literatur (Germany)
Publisher : Unknown
Page : 431 pages
File Size : 53,8 Mb
Release : 1989
Category : Brain
ISBN : 0895742977

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Fundamentals of Memory Formation by Akademie der Wissenschaften und der Literatur (Germany) Pdf

Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
Publisher : National Academies Press
Page : 195 pages
File Size : 52,6 Mb
Release : 1992-01-01
Category : Medical
ISBN : 9780309045292

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Discovering the Brain by National Academy of Sciences,Institute of Medicine,Sandra Ackerman Pdf

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 55,9 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : Arjen van Ooyen,Markus Butz-Ostendorf
Publisher : Academic Press
Page : 592 pages
File Size : 53,7 Mb
Release : 2017-06-23
Category : Science
ISBN : 9780128038727

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The Rewiring Brain by Arjen van Ooyen,Markus Butz-Ostendorf Pdf

The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. Reviews the current state of knowledge of structural plasticity in the adult brain Gives a comprehensive overview of computational studies on structural plasticity Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage

Author : Christian Hölscher
Publisher : Cambridge University Press
Page : 509 pages
File Size : 42,5 Mb
Release : 2001
Category : Medical
ISBN : 9780521770675

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Neuronal Mechanisms of Memory Formation by Christian Hölscher Pdf

Long-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between the two forms of synaptic plasticity. In this book, an international group of neurobiologists and psychologists discuss their latest ideas and data. The results of experiments using electrophysiological techniques in vitro are discussed and compared with the results of in vivo experiments. Learning experiments are also discussed. Theoretical models such as the Hebb theory of synaptic changes during learning are compared to different models that do not predict upregulation of synaptic transmission. A wide approach is taken, and research and models in different brain areas such as the neocortex and the basal brain are discussed.

Author : Akademie der Wissenschaften und der Literatur (Mainz),Hinrich Rahmann
Publisher : Unknown
Page : 431 pages
File Size : 46,9 Mb
Release : 1989
Category : Brain
ISBN : 343730612X

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Fundamentals of Memory Formation by Akademie der Wissenschaften und der Literatur (Mainz),Hinrich Rahmann Pdf

Author : Catherine Belzung,Peter Wigmore
Publisher : Springer Science & Business Media
Page : 447 pages
File Size : 52,9 Mb
Release : 2014-07-08
Category : Medical
ISBN : 9783642362323

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Neurogenesis and Neural Plasticity by Catherine Belzung,Peter Wigmore Pdf

This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.

Author : H. Rahmann
Publisher : Unknown
Page : 128 pages
File Size : 53,8 Mb
Release : 1989
Category : Electronic
ISBN : 008957429X

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Fundamentals of Memory Formation by H. Rahmann Pdf

Author : James L. McGaugh,Federico Berm£dez-Rattoni,Roberto A. Prado-Alcal,Roberto A. Prado-Alcala
Publisher : Routledge
Page : 220 pages
File Size : 48,5 Mb
Release : 2019-01-22
Category : Psychology
ISBN : 9781317729013

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Plasticity in the Central Nervous System by James L. McGaugh,Federico Berm£dez-Rattoni,Roberto A. Prado-Alcal,Roberto A. Prado-Alcala Pdf

Catalyzed by the development of new neurobiological and behavioral techniques as well as new conceptual and theoretical approaches to the study of the relationship between brain and behavior, research exploring brain functions enabling learning and memory has greatly accelerated in recent years. The chapters in this book reflect current theoretical approaches to the study of brain and memory and provide new insights concerning the cellular bases of memory and the differential involvement of brain systems in different forms of memory. By presenting up-to-date summaries of research investigating brain mechanisms underlying learning and memory, these chapters help to place current findings in appropriate theoretical context, and further stimulate research inquiry attempting to understand how the brain makes memory. Divided into three sections, coverage in this volume includes: * a discussion of pharmacological approaches to the study of brain and memory; * a review of experiments using a variety of techniques, including brain lesions, brain grafting, and electrophysiological recording to investigate the role of different brain regions in learning and memory; and * an examination of molecular analyses of events associated with memory formation.

Author : Bryan Kolb
Publisher : Psychology Press
Page : 226 pages
File Size : 45,8 Mb
Release : 1995
Category : Brain
ISBN : 0805815201

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Brain Plasticity and Behavior by Bryan Kolb Pdf

First Published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.