Radiation Induced Molecular Phenomena In Nucleic Acids

Author : Manoj Shukla,Jerzy Leszczynski
Publisher : Springer Science & Business Media
Page : 677 pages
File Size : 49,6 Mb
Release : 2008-05-08
Category : Science
ISBN : 9781402081842

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Radiation Induced Molecular Phenomena in Nucleic Acids by Manoj Shukla,Jerzy Leszczynski Pdf

Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book. NABs are highly photostable; the absorbed energy is dissipated in the form of ultrafast nonradiative decay. This book highlights the possible mechanisms of these phenomena which is important for all living species and discusses technical challenges in exploration of these processes.

Author : Mario Barbatti,Antonio Carlos Borin,Susanne Ullrich
Publisher : Springer
Page : 280 pages
File Size : 45,6 Mb
Release : 2014-12-26
Category : Science
ISBN : 9783319132723

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Photoinduced Phenomena in Nucleic Acids II by Mario Barbatti,Antonio Carlos Borin,Susanne Ullrich Pdf

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Author : Mario Barbatti,Antonio Carlos Borin,Susanne Ullrich
Publisher : Springer
Page : 362 pages
File Size : 43,8 Mb
Release : 2014-12-26
Category : Science
ISBN : 9783319133713

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Photoinduced Phenomena in Nucleic Acids I by Mario Barbatti,Antonio Carlos Borin,Susanne Ullrich Pdf

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students

Author : Mario Barbatti,Antonio Carlos Borin,Susanne Ullrich
Publisher : Unknown
Page : 372 pages
File Size : 43,5 Mb
Release : 2015-01-31
Category : Electronic
ISBN : 3319133721

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Photoinduced Phenomena in Nucleic Acids I by Mario Barbatti,Antonio Carlos Borin,Susanne Ullrich Pdf

Author : D. Schulte-Frohlinde,C. Von Sonntag,J. Huttermann
Publisher : CRC Press
Page : 138 pages
File Size : 53,5 Mb
Release : 1989
Category : Active oxygen
ISBN : 3718648741

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Free-Radical and Radiation-Induced Damage to DNA by D. Schulte-Frohlinde,C. Von Sonntag,J. Huttermann Pdf

Author : G. Ahnström
Publisher : Springer
Page : 416 pages
File Size : 53,8 Mb
Release : 1978
Category : Science
ISBN : UOM:39015004350727

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Effects of Ionizing Radiation on DNA by G. Ahnström Pdf

Author : Wolfram Schnabel
Publisher : John Wiley & Sons
Page : 360 pages
File Size : 48,6 Mb
Release : 2014-01-10
Category : Technology & Engineering
ISBN : 9783527677733

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Polymers and Electromagnetic Radiation by Wolfram Schnabel Pdf

This first book to cover the interaction of polymers with radiation from the entire electromagnetic spectrum adopts a multidisciplinary approach to bridge polymer chemistry and physics, photochemistry, photophysics and materials science. The text is equally unique in its scope, devoting equal amounts of attention to the three aspects of synthesis, characterization, and applications. The first part deals with the interaction of polymers with non-ionizing radiation in the frequency-range from sub-terahertz via infrared radiation to visible and ultraviolet light, while the second covers interaction with ionizing radiation from the extreme ultraviolet to ?-ray photons. The result is a systematic overview of how both types of radiation can be used for different polymerization approaches, spectroscopy methods and lithography techniques. Authored by a world-renowned researcher and teacher with over 40 years of experience in the field, this is a highly practical and authoritative guide.

Author : Michael D. Greenberg
Publisher : John Wiley & Sons
Page : 400 pages
File Size : 50,6 Mb
Release : 2009-09-22
Category : Science
ISBN : 9780470526262

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Radical and Radical Ion Reactivity in Nucleic Acid Chemistry by Michael D. Greenberg Pdf

Comprehensive coverage of radical reactive intermediates in nucleic acid chemistry and biochemistry The Wiley Series on Reactive Intermediates in Chemistry and Biology investigates reactive intermediates from the broadest possible range of disciplines. The contributions in each volume offer readers fresh insights into the latest findings, emerging applications, and ongoing research in the field from a diverse perspective. The chemistry and biochemistry of reactive intermediates is central to organic chemistry and biochemistry, and underlies a significant portion of modern synthetic chemistry. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides the only comprehensive review of the chemistry and biochemistry of nucleic acid radical intermediates. With contributions by world leaders in the field, the text covers a broad range of topics, including: A discussion of the relevant theory Ionization of DNA Nucleic acid sugar radicals Halopyrimidines Oxidative, reductive, and low energy electron transfer Electron affinity sensitizers Photochemical generative of reactive oxygen species Reactive nitrogen species Enediyne rearrangements Phenoxyl radicals A unique compilation on the cutting edge of our understanding, Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides an unparalleled resource to student and professional researchers in such fields as organic chemistry, biochemistry, molecular biology, and physical chemistry, as well as the industries associated with these disciplines.

Author : Gustavo García Gómez-Tejedor,Martina Christina Fuss
Publisher : Springer Science & Business Media
Page : 508 pages
File Size : 52,7 Mb
Release : 2012-01-04
Category : Science
ISBN : 9789400725645

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Radiation Damage in Biomolecular Systems by Gustavo García Gómez-Tejedor,Martina Christina Fuss Pdf

Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada, the USA and Australia. This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. An extensive Part I deals with recent experimental and theoretical findings on radiation induced damage at the molecular level. It includes many contributions on electron and positron collisions with biologically relevant molecules. X-ray and ion interactions are also covered. Part II addresses different approaches to radiation damage modelling. In Part III biomedical aspects of radiation effects are treated on different scales. After the physics-oriented focus of the previous parts, there is a gradual transition to biology and medicine with the increasing size of the object studied. Finally, Part IV is dedicated to current trends and novel techniques in radiation reserach and the applications hence arising. It includes new developments in radiotherapy and related cancer therapies, as well as technical optimizations of accelerators and totally new equipment designs, giving a glimpse of the near future of radiation-based medical treatments.

Author : Anders Lund,Masaru Shiotani
Publisher : Springer
Page : 773 pages
File Size : 44,6 Mb
Release : 2014-10-20
Category : Science
ISBN : 9783319092164

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Applications of EPR in Radiation Research by Anders Lund,Masaru Shiotani Pdf

Applications of EPR in Radiation Research is a multi-author contributed volume presented in eight themes: I. Elementary radiation processes (in situ and low temperature radiolysis, quantum solids); II: Solid state radiation chemistry (crystalline, amorphous and heterogeneous systems); III: Biochemistry, biophysics and biology applications (radicals in biomaterials, spin trapping, free-radical-induced DNA damage); IV: Materials science (polymeric and electronic materials, materials for treatment of nuclear waste, irradiated food); V: Radiation metrology (EPR-dosimetry, retrospective and medical applications); VI: Geological dating; VII: Advanced techniques (PELDOR, ESE and ENDOR spectroscopy, matrix isolation); VIII: Theoretical tools (density-functional calculations, spectrum simulations).

Author : J. Donald Chapman,Alan E. Nahum
Publisher : CRC Press
Page : 190 pages
File Size : 43,6 Mb
Release : 2016-04-21
Category : Science
ISBN : 9781439862605

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Radiotherapy Treatment Planning by J. Donald Chapman,Alan E. Nahum Pdf

Understand Quantitative Radiobiology from a Radiation Biophysics Perspective In the field of radiobiology, the linear-quadratic (LQ) equation has become the standard for defining radiation-induced cell killing. Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology describes tumor cell inactivation from a radiation physics perspective and offers appropriate LQ parameters for modeling tumor and normal tissue responses. Explore the Latest Cell Killing Numbers for Defining Iso-Effective Cancer Treatments The book compiles radiation mechanism information from biophysical publications of the past 50 years, addressing how ionizing radiation produces the killing of stem cells in human tumors. It presents several physical and chemical parameters that can modulate the radiation response of clonogenic cells in tumors. The authors describe the use of the LQ model in basic radiation mechanism studies with cells of relatively homogeneous radiation response and then extend the model to the fitting of survival data generated with heterogeneous cell populations (tumors). They briefly discuss how to use the LQ model for predicting tumor (local) control probability (TCP) and normal tissue complication probability (NTCP). The book also examines potential molecular targets related to alpha- and beta-inactivation and gives suggestions for further molecular characterizations of these two independent processes. Develop Efficacious, Patient-Friendly Treatments at Reduced Costs Focusing on quantitative radiobiology in LQ formulation, this book assists medical physicists and radiation oncologists in identifying improved cancer treatments. It also encourages investigators to translate potentially improved radiotherapy schedules based on TCP and NTCP modeling into actual patient benefit.

Author : Petr Carsky,Roman Curik
Publisher : CRC Press
Page : 296 pages
File Size : 52,8 Mb
Release : 2016-04-19
Category : Science
ISBN : 9781439839119

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Low-Energy Electron Scattering from Molecules, Biomolecules and Surfaces by Petr Carsky,Roman Curik Pdf

Since the turn of the 21st century, the field of electron molecule collisions has undergone a renaissance. The importance of such collisions in applications from radiation chemistry to astrochemistry has flowered, and their role in industrial processes such as plasma technology and lighting are vital to the advancement of next generation devices. Furthermore, the development of the scanning tunneling microscope highlights the role of such collisions in the condensed phase, in surface processing, and in the development of nanotechnology. Low-Energy Electron Scattering from Molecules, Biomolecules and Surfaces highlights recent progress in the theory and experiment of electron-molecule collisions, providing a detailed review of the current state of knowledge of electron molecule scattering—theoretical and experimental—for the general physicist and chemist interested in solving practical problems. In few other branches of science is the collaboration between theorists and experimentalists so topical. Covering advancements in practical problems, such as those met in plasma physics, microelectronics, nanolithography, DNA research, atmospheric chemistry, and astrochemistry, this book describes the formal general scattering theory and description of the experimental setup at a level the interested non-expert can appreciate.

Author : Jerzy Leszczynski,Manoj K. Shukla
Publisher : Springer Science & Business
Page : 436 pages
File Size : 52,9 Mb
Release : 2014-04-23
Category : Science
ISBN : 9781489974457

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Practical Aspects of Computational Chemistry III by Jerzy Leszczynski,Manoj K. Shukla Pdf

Theoretical and Computational Chemistry research has made unparalleled advancements in understanding every expanding area of science and technology. This volume presents the state-of-the-art research and progress made by eminent researchers in the area of theoretical computational chemistry and physics. The title mirrors the name of the annual international conference “Conference on Current Trends on Computational Chemistry” (CCTCC) which has become a popular discussion ground for eminent Theoretical and Computational Chemists and has been honored by the presence of several Nobel Laureates. Practical Aspects of Computational Chemistry III is aimed at theoretical and computational chemists, physical chemists, material scientists and those who are eager to apply computational chemistry methods to problems of chemical and physical importance. The book is a valuable resource for undergraduate, graduate and PhD students as well as established researchers.

Author : Gustavo García Gómez-Tejedor,Martina Christina Fuss
Publisher : Springer Science & Business Media
Page : 508 pages
File Size : 43,7 Mb
Release : 2012-01-05
Category : Science
ISBN : 9789400725638

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Radiation Damage in Biomolecular Systems by Gustavo García Gómez-Tejedor,Martina Christina Fuss Pdf

Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada, the USA and Australia. This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. An extensive Part I deals with recent experimental and theoretical findings on radiation induced damage at the molecular level. It includes many contributions on electron and positron collisions with biologically relevant molecules. X-ray and ion interactions are also covered. Part II addresses different approaches to radiation damage modelling. In Part III biomedical aspects of radiation effects are treated on different scales. After the physics-oriented focus of the previous parts, there is a gradual transition to biology and medicine with the increasing size of the object studied. Finally, Part IV is dedicated to current trends and novel techniques in radiation reserach and the applications hence arising. It includes new developments in radiotherapy and related cancer therapies, as well as technical optimizations of accelerators and totally new equipment designs, giving a glimpse of the near future of radiation-based medical treatments.

Author : James F. Wishart,B. S. Madhava Rao
Publisher : World Scientific
Page : 634 pages
File Size : 43,6 Mb
Release : 2010
Category : Science
ISBN : 9789814282079

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Recent Trends in Radiation Chemistry by James F. Wishart,B. S. Madhava Rao Pdf

This volume is a review of the trends in the field of radiation chemistry research. It covers a broad spectrum of topics, ranging from the historical perspective, instrumentation of accelerators in the nanosecond to femtosecond region, through the use ofradiation chemical methods in the study of antioxidants and nanomaterials, radiation-induced DNA damage by ionizing radiation involving both direct and indirect effects, to ultrafast events in free electron transfer, radiation-induced processes at solid-liquid interfaces and the recent work on infrared spectroscopy and radiation chemistry. The book is unique in that it covers a wide spectrum of topics that will be of great interest to beginners as well as experts. Recent data on ultrafast phenomena from the recently established world-class laser-driven accelerators facilities in the US, France and Japan are reviewed.