Principles Of Biochemical Toxicology

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Principles of Biochemical Toxicology, Third Edition

John Timbrell
Principles of Biochemical Toxicology Third Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 405 pages
File Size : 44,9 Mb
Release : 1999-10-21
Category : Medical
ISBN : 9780748407361

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Principles of Biochemical Toxicology, Third Edition by John Timbrell Pdf

Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Principles of Biochemical Toxicology

John A. Timbrell
Principles of Biochemical Toxicology Book PDF

Author : John A. Timbrell
Publisher : Unknown
Page : 405 pages
File Size : 53,9 Mb
Release : 1999
Category : Biochemical toxicology
ISBN : 100300430X

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Principles of Biochemical Toxicology by John A. Timbrell Pdf

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Principles of Biochemical Toxicology

John Timbrell
Principles of Biochemical Toxicology Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 405 pages
File Size : 52,7 Mb
Release : 1999-11-01
Category : Medical
ISBN : 1135737843

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Principles of Biochemical Toxicology by John Timbrell Pdf

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Principles of Biochemical Toxicology, Fourth Edition

John A. Timbrell
Principles of Biochemical Toxicology Fourth Edition Book PDF

Author : John A. Timbrell
Publisher : CRC Press
Page : 0 pages
File Size : 51,6 Mb
Release : 2008-11-18
Category : Medical
ISBN : 0849373026

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Principles of Biochemical Toxicology, Fourth Edition by John A. Timbrell Pdf

This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards. Principles of Biochemical Toxicology, Fourth Edition thoroughly explains dose-response relationships, disposition and metabolism, and toxic responses to foreign compounds, and presents detailed examples to make the mechanisms of toxicity more accessible to students encountering the subject for the first time. Comprehensive in scope with a clear and concise approach, the text includes summary sections, questions and model answers, and thoroughly revised artwork that serves as an essential aid to learning and teaching. New to the Fourth Edition: reorganized sections that cover basic principles followed by sections on different types of toxicity extensive use of examples throughout and numerous explanatory diagrams new material on risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen and asbestos proliferators, domoic acid, bone marrow (benzene), heart (adriamycin), blood (primaquine), biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, ethanol, botox, arsenic, and more questions with answers for each chapter for review and self-checking expanded and updated chapter bibliographies

Introduction to Toxicology, Third Edition

John Timbrell
Introduction to Toxicology Third Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 238 pages
File Size : 50,7 Mb
Release : 2001-11-15
Category : Medical
ISBN : 0415247632

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Introduction to Toxicology, Third Edition by John Timbrell Pdf

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Principles of Biochemical Toxicology, Second Edition

John Timbrell
Principles of Biochemical Toxicology Second Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 436 pages
File Size : 43,6 Mb
Release : 1991-10-28
Category : Medical
ISBN : UCSC:32106015829101

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Principles of Biochemical Toxicology, Second Edition by John Timbrell Pdf

This text, drawing upon the range of toxicology literature, sets down the fundamental principles of toxicology and pharmacology and goes on to cover recent developments in the field. The emphasis of the book is on biomechanical mechanisms. This second edition contains more examples.

Molecular and Biochemical Toxicology

Robert C. Smart,Ernest Hodgson
Molecular and Biochemical Toxicology Book PDF

Author : Robert C. Smart,Ernest Hodgson
Publisher : John Wiley & Sons
Page : 1060 pages
File Size : 45,8 Mb
Release : 2018-01-04
Category : Science
ISBN : 9781119042419

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Molecular and Biochemical Toxicology by Robert C. Smart,Ernest Hodgson Pdf

Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Introduction to Toxicology

John Timbrell
Introduction to Toxicology Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 238 pages
File Size : 51,7 Mb
Release : 2019-10-30
Category : Medical
ISBN : 9781000026986

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Introduction to Toxicology by John Timbrell Pdf

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Principles of Toxicology, Second Edition

Stine Karen,Thomas M. Brown
Principles of Toxicology Second Edition Book PDF

Author : Stine Karen,Thomas M. Brown
Publisher : CRC Press
Page : 392 pages
File Size : 54,7 Mb
Release : 2006-01-24
Category : Medical
ISBN : 9780849328565

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Principles of Toxicology, Second Edition by Stine Karen,Thomas M. Brown Pdf

Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:

Toxicology

M A SUBRAMANIAN
Toxicology Book PDF

Author : M A SUBRAMANIAN
Publisher : MJP Publisher
Page : 350 pages
File Size : 48,6 Mb
Release : 2019-06-06
Category : Medical
ISBN : 8210379456XXX

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Toxicology by M A SUBRAMANIAN Pdf

The study of toxicants—their route of entry, theirabsorption, distribution, elimination and transformation,and their dynamics within organisms and theenvironment—have been clearly dealt with in this book. Itprovides a concise, well-balanced and technicalintroduction to toxicology with focus on the basic principlesand concepts. It would prove to be a complete study unit fornew entrants to this field. The chapter “Impact of pollutantson aquatic organisms” has been written exclusively basedon the author’s laboratory observations.

Biochemical Ecotoxicology

Francois Gagne
Biochemical Ecotoxicology Book PDF

Author : Francois Gagne
Publisher : Elsevier
Page : 282 pages
File Size : 41,9 Mb
Release : 2014-07-07
Category : Medical
ISBN : 9780124116238

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Biochemical Ecotoxicology by Francois Gagne Pdf

Biochemical Ecotoxicology: Principles and Methods presents practical approaches to biochemical ecotoxicology experiments for environmental protection and conservation. With its methodical, stepped approach this essential reference introduces readers to current techniques for toxicity endpoint testing, suitable for laboratories of any size and budget. Each chapter presents a state-of-the-art principle, a quick and inexpensive procedure (including appropriate reagents), case studies, and demonstrations on how to analyze your results. Generic techniques are covered, suitable for a variety of organisms, as well as high-throughput techniques like quantitative polymerase chain reactions and enzyme-linked immunoassays. Cutting-edge approaches, including gPCR arrays and lipidomic techniques, are also included, making this is an essential reference for anyone who needs to assess environmental toxicity. Practical, cost-effective approaches to assess environmental toxicity endpoints for all types of organism Presents theory, methods, case studies and information on how to analyze results State-of-the-art techniques, such as ‘omics’ approaches to toxicology

Study Toxicology Through Questions

John Timbrell
Study Toxicology Through Questions Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 156 pages
File Size : 51,6 Mb
Release : 1997-06-17
Category : Medical
ISBN : 0748406956

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Study Toxicology Through Questions by John Timbrell Pdf

A compilation of questions with answers for students of toxicology. The questions are a mixture of short answer, problem-solving, data interpretation and multiple choice and cover all the major areas of toxicology.

Introduction to Biochemical Toxicology

Ernest Hodgson,Robert C. Smart
Introduction to Biochemical Toxicology Book PDF

Author : Ernest Hodgson,Robert C. Smart
Publisher : Wiley-Interscience
Page : 0 pages
File Size : 53,8 Mb
Release : 2001-02-09
Category : Science
ISBN : 0471333344

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Introduction to Biochemical Toxicology by Ernest Hodgson,Robert C. Smart Pdf

Introduction to Biochemical Toxicology Third Edition Over the past several decades, biochemical toxicology has contributed greatly to the advancement of scientific disciplines ranging from medicine and pharmacology to environmental science and industrial hygiene. In its never-ending quest to define the biochemical, cellular, and molecular events occurring when toxicants interact with organisms, biochemical toxicology provides the rational basis for, among other things, our understanding of acute and chronic toxic processes, the development of new therapies, the determination of toxic hazards, and the development of medical and agricultural biocides. Recent applications of new molecular and cellular techniques have greatly expanded our knowledge of how toxicants produce their adverse effects. As a consequence, the time has come for a substantial revision of Professor Ernest Hodgson's classic reference in the field. This Third Edition now contains updated overview chapters on immunochemical and molecular techniques. It also features entirely new chapters covering such crucial topics as immunotoxicology, cutaneous toxicology, reproductive and developmental toxicology, and molecular epidemiology.

Mechanistic Toxicology

Urs A. Boelsterli
Mechanistic Toxicology Book PDF

Author : Urs A. Boelsterli
Publisher : CRC Press
Page : 424 pages
File Size : 51,9 Mb
Release : 2007-03-23
Category : Medical
ISBN : 0849372720

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Mechanistic Toxicology by Urs A. Boelsterli Pdf

A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology

Principles of Toxicology Testing

Frank A. Barile
Principles of Toxicology Testing Book PDF

Author : Frank A. Barile
Publisher : CRC Press
Page : 338 pages
File Size : 44,8 Mb
Release : 2007-07-23
Category : Medical
ISBN : 9781420008326

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Principles of Toxicology Testing by Frank A. Barile Pdf

The evolution of toxicology testing finds its impetus in the continuing growth of the chemical and pharmaceutical industries, as well as the awareness of public health initiatives, needs, and responses that demand faster, more accurate, more economical methods for screening potential toxicity. Concurrent advances in biotechnology enable viable in v