Principles Of Biochemical Toxicology Fourth Edition

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Principles of Biochemical Toxicology, Fourth Edition

John A. Timbrell
Principles of Biochemical Toxicology Fourth Edition Book PDF

Author : John A. Timbrell
Publisher : CRC Press
Page : 0 pages
File Size : 48,6 Mb
Release : 2008-11-18
Category : Medical
ISBN : 0849373026

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Principles of Biochemical Toxicology, Fourth Edition by John A. Timbrell Pdf

This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards. Principles of Biochemical Toxicology, Fourth Edition thoroughly explains dose-response relationships, disposition and metabolism, and toxic responses to foreign compounds, and presents detailed examples to make the mechanisms of toxicity more accessible to students encountering the subject for the first time. Comprehensive in scope with a clear and concise approach, the text includes summary sections, questions and model answers, and thoroughly revised artwork that serves as an essential aid to learning and teaching. New to the Fourth Edition: reorganized sections that cover basic principles followed by sections on different types of toxicity extensive use of examples throughout and numerous explanatory diagrams new material on risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen and asbestos proliferators, domoic acid, bone marrow (benzene), heart (adriamycin), blood (primaquine), biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, ethanol, botox, arsenic, and more questions with answers for each chapter for review and self-checking expanded and updated chapter bibliographies

Principles of Biochemical Toxicology, Third Edition

John Timbrell
Principles of Biochemical Toxicology Third Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 405 pages
File Size : 52,6 Mb
Release : 1999-10-21
Category : Medical
ISBN : 9780748407361

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Principles of Biochemical Toxicology, Third Edition by John Timbrell Pdf

Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Introduction to Toxicology, Third Edition

John Timbrell
Introduction to Toxicology Third Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 238 pages
File Size : 55,9 Mb
Release : 2001-11-15
Category : Medical
ISBN : 0415247632

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Introduction to Toxicology, Third Edition by John Timbrell Pdf

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Principles of Biochemical Toxicology

John A. Timbrell
Principles of Biochemical Toxicology Book PDF

Author : John A. Timbrell
Publisher : Unknown
Page : 405 pages
File Size : 52,8 Mb
Release : 1999
Category : Biochemical toxicology
ISBN : 100300430X

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Principles of Biochemical Toxicology by John A. Timbrell Pdf

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Principles of Biochemical Toxicology

John Timbrell
Principles of Biochemical Toxicology Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 405 pages
File Size : 42,5 Mb
Release : 1999-11-01
Category : Medical
ISBN : 1135737843

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Principles of Biochemical Toxicology by John Timbrell Pdf

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Molecular and Biochemical Toxicology

Robert C. Smart,Ernest Hodgson
Molecular and Biochemical Toxicology Book PDF

Author : Robert C. Smart,Ernest Hodgson
Publisher : John Wiley & Sons
Page : 1060 pages
File Size : 53,8 Mb
Release : 2018-01-04
Category : Science
ISBN : 9781119042419

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Molecular and Biochemical Toxicology by Robert C. Smart,Ernest Hodgson Pdf

Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Introduction to Toxicology

John Timbrell
Introduction to Toxicology Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 238 pages
File Size : 48,7 Mb
Release : 2019-10-30
Category : Medical
ISBN : 9781000026986

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Introduction to Toxicology by John Timbrell Pdf

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Principles of Biochemical Toxicology, Second Edition

John Timbrell
Principles of Biochemical Toxicology Second Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 436 pages
File Size : 48,6 Mb
Release : 1991-10-28
Category : Medical
ISBN : UCSC:32106015829101

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Principles of Biochemical Toxicology, Second Edition by John Timbrell Pdf

This text, drawing upon the range of toxicology literature, sets down the fundamental principles of toxicology and pharmacology and goes on to cover recent developments in the field. The emphasis of the book is on biomechanical mechanisms. This second edition contains more examples.

Principles of Toxicology, Second Edition

Stine Karen,Thomas M. Brown
Principles of Toxicology Second Edition Book PDF

Author : Stine Karen,Thomas M. Brown
Publisher : CRC Press
Page : 392 pages
File Size : 48,6 Mb
Release : 2006-01-24
Category : Medical
ISBN : 9780849328565

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Principles of Toxicology, Second Edition by Stine Karen,Thomas M. Brown Pdf

Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:

Principles of Ecotoxicology, Fourth Edition

C.H. Walker,R.M. Sibly,S.P. Hopkin,D.B. Peakall
Principles of Ecotoxicology Fourth Edition Book PDF

Author : C.H. Walker,R.M. Sibly,S.P. Hopkin,D.B. Peakall
Publisher : CRC Press
Page : 389 pages
File Size : 42,7 Mb
Release : 2012-03-12
Category : Science
ISBN : 9781439862667

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Principles of Ecotoxicology, Fourth Edition by C.H. Walker,R.M. Sibly,S.P. Hopkin,D.B. Peakall Pdf

Cutting across traditional subject boundaries, Principles of Ecotoxicology, Fourth Edition gives readers an integrated view of ecotoxicology, from molecules to ecosystems. This new edition of a bestselling textbook continues to emphasize principles rather than practice, providing the interdisciplinary perspective and grounding required for research. Organized into three sections, the book first describes the molecular structures, properties, and environmental fate of pollutants. It then deals with the effects of pollutants on living organisms at the molecular, cellular, and individual levels. Moving into population biology and population genetics, the third part of the book addresses a question of great interest to ecologists: What effects do pollutants have at the levels of population, community, and the whole ecosystem? The book also looks at how ecotoxicology is used in the biomonitoring of environmental pollution, the investigation of pollution problems, the conducting of field trials, the study of the development of resistance, and the growing area of environmental risk assessments. Throughout, examples and case studies illustrate the principles. This updated fourth edition includes new material on nanoparticle pollution, bioaccumulation, biomarkers, and chemical warfare in nature, as well as a new chapter on the future directions of ecotoxicology. A concise textbook that will also appeal to practicing ecotoxicologists, it provides a solid basis for understanding what happens to chemicals in the real world, where they go, how they ultimately degrade, and how they affect the individuals and populations that encounter them. What’s New in This Edition Revised and updated material throughout A chapter on future directions of ecotoxicology New material on nanoparticle pollution and chemical warfare in nature Expanded coverage of bioaccumulation, biomarkers, and risk assessment for affected populations More case studies, many from the United States Discussion of neurotoxic and behavioral effects of pollutants Recent research on the decline of vultures and effects of neonicotinoids on bees Organic Pollutants: An Ecotoxicological Perspective, Second Edition (CRC Press, 2008), a companion volume to this book, covers the mechanistic aspects of ecotoxicology in more depth.

A Textbook of Modern Toxicology

Ernest Hodgson
A Textbook of Modern Toxicology Book PDF

Author : Ernest Hodgson
Publisher : John Wiley & Sons
Page : 601 pages
File Size : 52,7 Mb
Release : 2011-09-20
Category : Science
ISBN : 9781118211298

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A Textbook of Modern Toxicology by Ernest Hodgson Pdf

A Textbook of Modern Toxicology is a unique resource that provides both students and practitioners with a wide-ranging, accessible overview of the discipline. Suitable for courses in environmental, pharmacological, medical, and veterinary toxicology, this essential text features chapters written by experts who address a range of key topics. The Fourth Edition includes additional chapters on new approaches to toxicology - molecular methods (-omics: toxicogenomics, proteomics, and metabolomics), bioinformatics, and systems biology – and continues the legacy of its predecessors to provide up-to-date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity testing, ecological risk assessment, and many other areas of toxicology that help foster a solid comprehension of the field. Also featured in the Fourth Edition are end-of-chapter questions and a Solutions Manual available separately for academic adopters.

Principles of Ecotoxicology

C.H. Walker
Principles of Ecotoxicology Book PDF

Author : C.H. Walker
Publisher : CRC Press
Page : 348 pages
File Size : 49,9 Mb
Release : 1996-04-11
Category : Science
ISBN : UOM:39076001839500

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Principles of Ecotoxicology by C.H. Walker Pdf

Environmental pollution is caused by a wide range of chemicals released as a consequence of human activities. This book aims to identify major classes of pollutants and their environmental fate, before going on to consider the effects that they might have on individual organisms and ecosystems. The book progresses from the molecular basis of pollutant toxicity to consequent effects at higher levels of organization - cellular, whole organism, population, community and ecosystem.; The book defines ecotoxicology as the study of the harmful effects of chemicals upon ecosystems. It is an interdisciplinary subject which represents a synthesis of elements from the disciplines of chemistry, biochemistry, toxicology, physiology, population ecology and population genetics. In contrast to "classical" toxicology, the ultimate concern is for the effects at the level of populations and consequent effects at the level of populations.

Mechanistic Toxicology

Urs A. Boelsterli
Mechanistic Toxicology Book PDF

Author : Urs A. Boelsterli
Publisher : CRC Press
Page : 424 pages
File Size : 42,5 Mb
Release : 2007-03-23
Category : Medical
ISBN : 0849372720

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Mechanistic Toxicology by Urs A. Boelsterli Pdf

A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology

A Textbook of Modern Toxicology

Ernest Hodgson,Patricia E. Levi
A Textbook of Modern Toxicology Book PDF

Author : Ernest Hodgson,Patricia E. Levi
Publisher : Unknown
Page : 428 pages
File Size : 44,6 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015011655860

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A Textbook of Modern Toxicology by Ernest Hodgson,Patricia E. Levi Pdf

Designed as an introductory textbook, the book emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology.

Toxicology Principles for the Industrial Hygienist

William E. Luttrell,Warren W. Jederberg,Kenneth R. Still
Toxicology Principles for the Industrial Hygienist Book PDF

Author : William E. Luttrell,Warren W. Jederberg,Kenneth R. Still
Publisher : AIHA
Page : 468 pages
File Size : 51,9 Mb
Release : 2008
Category : Technology & Engineering
ISBN : 9781931504881

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Toxicology Principles for the Industrial Hygienist by William E. Luttrell,Warren W. Jederberg,Kenneth R. Still Pdf

Focuses on the applications of toxicology principles to the practice of industrial hygiene, using case studies as examples.