Principles Of Biochemical Toxicology Third Edition

Author : John Timbrell
Publisher : CRC Press
Page : 405 pages
File Size : 53,9 Mb
Release : 1999-10-21
Category : Medical
ISBN : 9780748407361

Get Book

Principles of Biochemical Toxicology, Third Edition by John Timbrell Pdf

Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Author : John Timbrell
Publisher : CRC Press
Page : 238 pages
File Size : 42,8 Mb
Release : 2001-11-15
Category : Medical
ISBN : 0415247632

Get Book

Introduction to Toxicology, Third Edition by John Timbrell Pdf

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Author : John A. Timbrell
Publisher : Unknown
Page : 405 pages
File Size : 47,7 Mb
Release : 1999
Category : Biochemical toxicology
ISBN : 100300430X

Get Book

Principles of Biochemical Toxicology by John A. Timbrell Pdf

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Author : John Timbrell
Publisher : CRC Press
Page : 394 pages
File Size : 54,8 Mb
Release : 1999-11-01
Category : Medical
ISBN : 1135737894

Get Book

Principles of Biochemical Toxicology by John Timbrell Pdf

Author : Thomas A Gossel
Publisher : CRC Press
Page : 464 pages
File Size : 47,8 Mb
Release : 1994-06-30
Category : Medical
ISBN : 0781701252

Get Book

Principles Of Clinical Toxicology, Third Edition by Thomas A Gossel Pdf

In this third edition, the editors have accounted for the numerous changes in protocols for managing poison ingestions and have again provided an indispensable resource for all students of pharmacy and the health sciences on the basic principles of clinical toxicology. The book's unique focus on the fundamentals helps the reader understand why events occur and why a particular treatment is selected. Each chapter presents pertinent information on classes of toxic agents, their common sources and usual methods of intoxication, incidence and frequency of poisoning, mechanisms of action, clinical signs and symptoms of poisoning and management guidance. The text includes illustrative case studies, carefully selected to reinforce the information covered. Each chapter concludes with review questions to further enhance comprehension.

Author : John Timbrell
Publisher : CRC Press
Page : 436 pages
File Size : 42,6 Mb
Release : 1991-10-28
Category : Medical
ISBN : UCSC:32106015829101

Get Book

Principles of Biochemical Toxicology, Second Edition by John Timbrell Pdf

This text, drawing upon the range of toxicology literature, sets down the fundamental principles of toxicology and pharmacology and goes on to cover recent developments in the field. The emphasis of the book is on biomechanical mechanisms. This second edition contains more examples.

Author : John A. Timbrell
Publisher : CRC Press
Page : 0 pages
File Size : 43,9 Mb
Release : 2008-11-18
Category : Medical
ISBN : 0849373026

Get Book

Principles of Biochemical Toxicology, Fourth Edition by John A. Timbrell Pdf

This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards. Principles of Biochemical Toxicology, Fourth Edition thoroughly explains dose-response relationships, disposition and metabolism, and toxic responses to foreign compounds, and presents detailed examples to make the mechanisms of toxicity more accessible to students encountering the subject for the first time. Comprehensive in scope with a clear and concise approach, the text includes summary sections, questions and model answers, and thoroughly revised artwork that serves as an essential aid to learning and teaching. New to the Fourth Edition: reorganized sections that cover basic principles followed by sections on different types of toxicity extensive use of examples throughout and numerous explanatory diagrams new material on risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen and asbestos proliferators, domoic acid, bone marrow (benzene), heart (adriamycin), blood (primaquine), biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, ethanol, botox, arsenic, and more questions with answers for each chapter for review and self-checking expanded and updated chapter bibliographies

Author : Stine Karen,Thomas M. Brown
Publisher : CRC Press
Page : 392 pages
File Size : 45,6 Mb
Release : 2006-01-24
Category : Medical
ISBN : 9780849328565

Get Book

Principles of Toxicology, Second Edition by Stine Karen,Thomas M. Brown Pdf

Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:

Author : Karen E. Stine,Thomas M. Brown
Publisher : CRC Press
Page : 0 pages
File Size : 52,8 Mb
Release : 2015-04-16
Category : Medical
ISBN : 1466503424

Get Book

Principles of Toxicology, Third Edition by Karen E. Stine,Thomas M. Brown Pdf

Reflecting the broad and interdisciplinary nature of toxicology, this third edition of Principles of Toxicology explores the biochemical, physiological, and environmental aspects of the subject. This new edition is updated and revised to include reference to several major new directions in the science of toxicology, including significant changes in thinking about cancer and carcinogenesis as well as the rapid expansion of toxicogenomics. The book also includes new chapters on topics of timely interest such as radiation, food safety, and natural toxins. As in previous editions, chapters combine background material in the appropriate discipline—which helps readers review and remember the basics—with new information on toxicology to stress key principles and concepts. Also included is a selection of updated case studies through which principles and concepts are applied to real-world issues. The book features an extensive cross-referencing system linking all sections and enhancing the integration of material, thus helping readers tie it all together. It also includes an appendix of selected toxicants that describes chemical structure, category of use, and toxicity. These features make specific information quick and easy to find. The easy-to-follow format and clear presentation of information in this book will make this one of the most useful references on your shelf.

Author : John Timbrell
Publisher : CRC Press
Page : 167 pages
File Size : 54,6 Mb
Release : 1995-02-27
Category : Medical
ISBN : 0748402411

Get Book

Introduction To Toxicology by John Timbrell Pdf

Since the publication of the first edition of this text, toxicology has become a more mature science and the number of courses has greatly increased. The need for an introductory text is, therefore, growing. This second edition caters for this need in a clear and easy-to-read style, featuring updated information and new examples, an extensively revised bibliography, essay type questions at the end of each chapter, illustrations and a glossary.; The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Author : Stephen M. Roberts,Robert C. James,Phillip L. Williams
Publisher : John Wiley & Sons
Page : 496 pages
File Size : 51,7 Mb
Release : 2015-01-12
Category : Science
ISBN : 9780470907917

Get Book

Principles of Toxicology by Stephen M. Roberts,Robert C. James,Phillip L. Williams Pdf

A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms

Author : Robert C. Smart,Ernest Hodgson
Publisher : John Wiley & Sons
Page : 1040 pages
File Size : 45,9 Mb
Release : 2017-11-06
Category : Science
ISBN : 9781119042433

Get Book

Molecular and Biochemical Toxicology by Robert C. Smart,Ernest Hodgson Pdf

Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Author : Robert C. Smart,Ernest Hodgson
Publisher : John Wiley & Sons
Page : 804 pages
File Size : 47,7 Mb
Release : 2013-03-05
Category : Science
ISBN : 9781118679722

Get Book

Molecular and Biochemical Toxicology by Robert C. Smart,Ernest Hodgson Pdf

An essential resource for graduate students, academic and industrial toxicologists, and environmental health scientists and professionals Over the course of thirty years and three editions, Introduction to Biochemical Toxicology has been an important source for coverage of the ongoing quest to define the biochemical, cellular, and molecular events induced by toxicants at the cellular and organismic levels. Now, as the principles and methods of molecular and cellular biology as well as genomic sciences play an ever increasing role in mechanistic toxicology, significant changes have been made to the book, resulting in this important new edition-now titled Molecular and Biochemical Toxicology, Fourth Edition. Much more than an introductory text, this crucial new edition has been completely revised to provide timely and thorough coverage of the underlying biochemical, molecular, and cellular mechanisms through which toxicants produce their adverse effects. Toxicological issues are covered from the molecule to the cell to the organ level. Complex methods used in toxicology are also described in a straightforward, easy-to-understand style. Additional features of this new edition include: New chapters that explore the interface between toxicology and genomic sciences, including: bioinformatics, proteomics, metabolomics, and toxicogenomics Increased emphasis on structure, mechanism, and regulation of xenobiotic metabolizing enzymes, toxicogenetics, and xenobiotic transporters Additional new chapters on: molecular epidemiology and genetic susceptibility, DNA damage and mutagenesis, DNA repair, mechanisms of cell death, mitochondrial dysfunction, metals, reproductive toxicology, developmental toxicology, and reactive oxygen/metabolites and toxicity Molecular and Biochemical Toxicology, Fourth Edition guides graduate students, toxicologists, and environmental health professionals through the principles of molecular and biochemical toxicology and the complex mechanisms of toxicity. Whether it's used in the classroom or in industry, research, or academia, this book is essential for anyone interested in understanding the molecular mechanisms through which toxicants produce adverse effects.

Author : Urs A. Boelsterli
Publisher : CRC Press
Page : 424 pages
File Size : 42,6 Mb
Release : 2007-03-23
Category : Medical
ISBN : 0849372720

Get Book

Mechanistic Toxicology by Urs A. Boelsterli Pdf

A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology

Author : Ernest Hodgson,Patricia E. Levi
Publisher : McGraw-Hill Medical Publishing
Page : 518 pages
File Size : 44,7 Mb
Release : 1997
Category : Medical
ISBN : UOM:39015041081293

Get Book

A Textbook of Modern Toxicology by Ernest Hodgson,Patricia E. Levi Pdf

This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.