Principles Of Biochemical Toxicology Second Edition

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Principles of Biochemical Toxicology, Third Edition

John Timbrell
Principles of Biochemical Toxicology Third Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 405 pages
File Size : 54,6 Mb
Release : 1999-10-21
Category : Medical
ISBN : 9780748407361

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Principles of Biochemical Toxicology, Third Edition by John Timbrell Pdf

Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Principles of Biochemical Toxicology, Second Edition

John Timbrell
Principles of Biochemical Toxicology Second Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 415 pages
File Size : 52,5 Mb
Release : 1991-10-28
Category : Medical
ISBN : 0850668328

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Principles of Biochemical Toxicology, Second Edition by John Timbrell Pdf

Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following the acclaimed first two editions of Principles of Biochemical Toxicology, the author has expanded the text to include summary sections, questions and model answers and thoroughly revised artwork. These features, plus the new easy-to-read format, will make biochemical toxicology more accessible to undergraduates and postgraduates encountering the subject for the first time. This comprehensive textbook provides a thorough explanation of dose-response relationships, disposition and metabolism, toxic responses to foreign compounds and detailed examples to illustrate mechanisms of toxicity. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Principles of Biochemical Toxicology

John A. Timbrell
Principles of Biochemical Toxicology Book PDF

Author : John A. Timbrell
Publisher : Unknown
Page : 405 pages
File Size : 50,7 Mb
Release : 1999
Category : Biochemical toxicology
ISBN : 100300430X

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Principles of Biochemical Toxicology by John A. Timbrell Pdf

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Principles of Biochemical Toxicology

John Timbrell
Principles of Biochemical Toxicology Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 405 pages
File Size : 54,7 Mb
Release : 1999-11-01
Category : Medical
ISBN : 1135737843

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Principles of Biochemical Toxicology by John Timbrell Pdf

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Principles of Toxicology, Second Edition

Stine Karen,Thomas M. Brown
Principles of Toxicology Second Edition Book PDF

Author : Stine Karen,Thomas M. Brown
Publisher : CRC Press
Page : 392 pages
File Size : 48,7 Mb
Release : 2006-01-24
Category : Medical
ISBN : 9780849328565

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Principles of Toxicology, Second Edition by Stine Karen,Thomas M. Brown Pdf

Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:

Principles of Biochemical Toxicology, Fourth Edition

John A. Timbrell
Principles of Biochemical Toxicology Fourth Edition Book PDF

Author : John A. Timbrell
Publisher : CRC Press
Page : 0 pages
File Size : 49,5 Mb
Release : 2008-11-18
Category : Medical
ISBN : 0849373026

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Principles of Biochemical Toxicology, Fourth Edition by John A. Timbrell Pdf

This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards. Principles of Biochemical Toxicology, Fourth Edition thoroughly explains dose-response relationships, disposition and metabolism, and toxic responses to foreign compounds, and presents detailed examples to make the mechanisms of toxicity more accessible to students encountering the subject for the first time. Comprehensive in scope with a clear and concise approach, the text includes summary sections, questions and model answers, and thoroughly revised artwork that serves as an essential aid to learning and teaching. New to the Fourth Edition: reorganized sections that cover basic principles followed by sections on different types of toxicity extensive use of examples throughout and numerous explanatory diagrams new material on risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen and asbestos proliferators, domoic acid, bone marrow (benzene), heart (adriamycin), blood (primaquine), biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, ethanol, botox, arsenic, and more questions with answers for each chapter for review and self-checking expanded and updated chapter bibliographies

Introduction to Toxicology, Third Edition

John Timbrell
Introduction to Toxicology Third Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 238 pages
File Size : 42,6 Mb
Release : 2001-11-15
Category : Medical
ISBN : 0415247632

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Introduction to Toxicology, Third Edition by John Timbrell Pdf

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Clinical Toxicology

Frank A. Barile
Clinical Toxicology Book PDF

Author : Frank A. Barile
Publisher : CRC Press
Page : 484 pages
File Size : 43,8 Mb
Release : 2010-02-15
Category : Medical
ISBN : 9781420092264

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Clinical Toxicology by Frank A. Barile Pdf

Examining the complex interactions associated with clinical toxicological events and chemical exposure of drug administration, this updated and revised Second Edition functions as a stand-alone text or reference of clinical toxicology for professionals, students of toxicology and pharmacy, as well as forensic toxicologists, occupational healthcare

Study Toxicology Through Questions

John Timbrell
Study Toxicology Through Questions Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 144 pages
File Size : 40,6 Mb
Release : 2017-08-25
Category : Medical
ISBN : 9780203484012

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Study Toxicology Through Questions by John Timbrell Pdf

A compilation of questions with answers for students of toxicology. The questions are a mixture of short answer, problem-solving, data interpretation and multiple choice and cover all the major areas of toxicology.

Molecular and Biochemical Toxicology

Robert C. Smart,Ernest Hodgson
Molecular and Biochemical Toxicology Book PDF

Author : Robert C. Smart,Ernest Hodgson
Publisher : John Wiley & Sons
Page : 1060 pages
File Size : 47,9 Mb
Release : 2018-01-04
Category : Science
ISBN : 9781119042419

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Molecular and Biochemical Toxicology by Robert C. Smart,Ernest Hodgson Pdf

Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

In Vitro Toxicology, Second Edition

Shayne C. Gad
In Vitro Toxicology Second Edition Book PDF

Author : Shayne C. Gad
Publisher : CRC Press
Page : 419 pages
File Size : 52,7 Mb
Release : 2000-11-02
Category : Medical
ISBN : 9781560327691

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In Vitro Toxicology, Second Edition by Shayne C. Gad Pdf

Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists a broad range of in vitro models for use in either identifying or understanding most forms of toxicity. The availability of in vitro models spans both the full range of endpoints (irritation, sensitization, lethality, mutagenicity, and devlopmental toxicity) and the full spectrum of target organ systems (skin, eye, heart, liver, kidney, nervous system, etc.). Chapters are devoted to each of these speciality areas from a perspective of presenting the principal models and their uses and limitations. Chapters that overview the principles involved in the general selection and use of models, and that address the issues of safety concerns and regulatory acceptance of these methods are also included.

Principles of Toxicology

Stephen M. Roberts,Robert C. James,Phillip L. Williams
Principles of Toxicology Book PDF

Author : Stephen M. Roberts,Robert C. James,Phillip L. Williams
Publisher : John Wiley & Sons
Page : 496 pages
File Size : 41,9 Mb
Release : 2015-01-12
Category : Science
ISBN : 9780470907917

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Principles of Toxicology by Stephen M. Roberts,Robert C. James,Phillip L. Williams Pdf

A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms

Mechanistic Toxicology

Urs A. Boelsterli
Mechanistic Toxicology Book PDF

Author : Urs A. Boelsterli
Publisher : CRC Press
Page : 424 pages
File Size : 40,8 Mb
Release : 2007-03-23
Category : Medical
ISBN : 0849372720

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Mechanistic Toxicology by Urs A. Boelsterli Pdf

A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology

Principles of Toxicology

Phillip L. Williams,Robert C. James,Stephen M. Roberts
Principles of Toxicology Book PDF

Author : Phillip L. Williams,Robert C. James,Stephen M. Roberts
Publisher : John Wiley & Sons
Page : 625 pages
File Size : 41,9 Mb
Release : 2003-10-10
Category : Science
ISBN : 9780471459231

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Principles of Toxicology by Phillip L. Williams,Robert C. James,Stephen M. Roberts Pdf

A fully updated and expanded edition of the bestselling guide on toxicology and its practical application The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields, Principles of Toxicology, Second Edition features: Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems Coverage of occupational medicine and epidemiological issues The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins Special emphasis on the evaluation and control of toxic hazards Specific case histories on applying risk assessment methods in the modern workplace Ample figures, references, and a comprehensive glossary of toxicological terms

Molecular Toxicology

P. David Josephy,Bengt Mannervik
Molecular Toxicology Book PDF

Author : P. David Josephy,Bengt Mannervik
Publisher : Unknown
Page : 620 pages
File Size : 52,7 Mb
Release : 2006
Category : Molecular toxicology
ISBN : 0195176200

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Molecular Toxicology by P. David Josephy,Bengt Mannervik Pdf

The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and molecular biological experimental techniques have helped researchers understand the precise effects of toxins and foreign compounds on living things atthe molecular, cellular, and organismal levels. Breakthrough research has recently been completed illuminating the human genome and the role of enzymes in toxic biochemical reaction mechanisms. Toxicology now covers drug metabolism and design, carcinogenesis, programmed cell death, and DNA repair,among other subjects. The second edition captures these and other advances, and broadens its scope to address the experimental science of toxicology. The first edition of Molecular Toxicology has become an indispensable resource for graduate students in molecular and biochemical toxicology courses,as well as academic researchers and industrial researchers in toxicology. Rigorously updated and revised, the new edition commands an unrivaled authority in the field of molecular toxicology.