Progress In Iron Research

Author : Chaim Hershko,Abraham M. Konijn,Philip Aisen
Publisher : Springer Science & Business Media
Page : 394 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461525547

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Progress in Iron Research by Chaim Hershko,Abraham M. Konijn,Philip Aisen Pdf

The 4th International Conference on Hemochromatosis and the 11th International Conference on Iron and Iron Proteins took place in Jerusalem on April 27 -30 and on May 2 -7 1993, respectively. The first, a clinical meeting, and the second, a forum designed primarily for basic scientists. Both meetings are held regularly on alter nate years and represent probably the most important forum for the exchange of information in iron research. The present volume "Progress in Iron Research" is based on a selection of presentations delivered at these meetings. However, this volume represents much more than a publication of conference proceedings. It offers a comprehensive state-of-the-art review on most aspects of iron metabolism. We have tried to offer a balanced review of the most important recent developments in iron research including both basic research and clinical investigation. However, the scope of chapters was based, by definition, on the actual participants at the meetings and some important fields in iron research such as plant physiology, microbial aspects of iron metabolism, and free radical research have not been dealt with. Many of the authors of the 40 chapters have beel). pt1rsonally responsible for some of the most important developments in iron research ~~vidffig: n~~~ights into iron physiology and pathophysiology. The Editors wish to express their gratitude for the outstanding and timely cooperation of all contributors to this volume.

Author : Institute of Medicine,Committee on the Prevention, Detection, and Management of Iron Deficiency Anemia Among U.S. Children and Women of Childbearing Age
Publisher : National Academies Press
Page : 139 pages
File Size : 49,9 Mb
Release : 1994-02-01
Category : Medical
ISBN : 9780309049870

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Iron Deficiency Anemia by Institute of Medicine,Committee on the Prevention, Detection, and Management of Iron Deficiency Anemia Among U.S. Children and Women of Childbearing Age Pdf

This book summarizes information related to public health measures on the prevention, detection, and management of iron deficiency anemia. It presents draft guidelines and recommendations related to this area, as applicable in primary health care and public health clinic settings, and it formulates recommendations for research. This volume is intended both to provide a common frame of reference for health professionals in preventing and treating iron deficiency anemia and to enable the U.S. Centers for Disease Control and Prevention to prepare national guidelines and recommendations for the prevention and control of iron deficiency anemia.

Author : Farooq Shah,Zafar Khan,Amjad Iqbal
Publisher : BoD – Books on Demand
Page : 268 pages
File Size : 52,5 Mb
Release : 2018-09-05
Category : Technology & Engineering
ISBN : 9781789236002

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Rice Crop by Farooq Shah,Zafar Khan,Amjad Iqbal Pdf

Rice is a staple crop in many coastal and non-coastal areas of the globe and requires a large production area. With the increasing trends in population , it is pivotal to increase the production of this important crop for sustainability. The introduction of high-yielding rice cultivars through molecular breeding is one of the possibilities that can ensure sustainability. Additionally, development of new biotic and abiotic stress-resistant cultivars with higher nutritional value can revolutionize the rice industry.

Author : Chaim Hershko
Publisher : Springer Science & Business Media
Page : 275 pages
File Size : 45,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461505938

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Iron Chelation Therapy by Chaim Hershko Pdf

Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

Author : Peggy L. Carver
Publisher : Walter de Gruyter GmbH & Co KG
Page : 640 pages
File Size : 40,9 Mb
Release : 2019-01-14
Category : Science
ISBN : 9783110526981

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Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic by Peggy L. Carver Pdf

Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron administration are pointed out. A subject of intense debate is the essentiality of chromium and vanadium. For example, chromium(III) compounds are taken as a nutritional supplement by athletes and bodybuilders; in contrast, chromate, Cr(VI), is toxic and a carcinogen for humans. The benefi cial and toxic effects of manganese, cobalt, and copper on humans are discussed. The need for antiparasitic agents is emphasized as well as the clinical aspects of metal-containing antidotes for cyanide poisoning. In addition to the essential and possibly essential ones, also other metal ions play important roles in human health, causing harm (like the metalloid arsenic, lead or cadmium) or being used in diagnosis or treatment of human diseases, like gadolinium, gallium, lithium, gold, silver or platinum. The impact of this vibrant research area on metals in the clinic is provided in 14 stimulating chapters, written by internationally recognized experts from the Americas, Europe and China, and is manifested by approximately 2000 references, and about 90 illustrations and tables. Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic is an essential resource for scientists working in the wide range from pharmacology, enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine ... not forgetting that it also provides excellent information for teaching.

Author : Clarence Jay West
Publisher : National Academies
Page : 100 pages
File Size : 40,8 Mb
Release : 1930
Category : Research, Industrial
ISBN : NAP:16378

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Five Years of Research in Industry, 1926-1930 by Clarence Jay West Pdf

Author : Susu M Zughaier,Pierre Cornelis
Publisher : Frontiers Media SA
Page : 156 pages
File Size : 52,8 Mb
Release : 2018-12-27
Category : Electronic
ISBN : 9782889456628

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The Role of Iron in Bacterial Pathogenesis by Susu M Zughaier,Pierre Cornelis Pdf

The collection of articles published in this eBook represent different facets of the interactions between pathogens and their host concerning the battle for iron. Pathogens have developed different strategies to acquire iron from their host. These include the production of siderophores, heme acquisition and ferrous iron uptake.

Author : Institute of Medicine,Committee on Micronutrient Deficiencies
Publisher : National Academies Press
Page : 222 pages
File Size : 52,6 Mb
Release : 1998-03-24
Category : Medical
ISBN : 9780309060295

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Prevention of Micronutrient Deficiencies by Institute of Medicine,Committee on Micronutrient Deficiencies Pdf

Micronutrient malnutrition affects approximately 2 billion people worldwide. The adverse effects of micronutrient deficiencies are profound and include premature death, poor health, blindness, growth stunting, mental retardation, learning disabilities, and low work capacity. Preventing Micronutrient Deficiencies provides a conceptual framework based on past experience that will allow funders to tailor programs to existing regional/country capabilities and to incorporate within these programs the capacity to address multiple strategies (i.e., supplementation/fortification/food-based approaches/public health measures) and multiple micronutrient deficiencies. The book does not offer recommendations on how to alleviate specific micronutrient deficienciesâ€"such recommendations are already available through the publications of diverse organizations, including the U.S. Agency for International Development, the Micronutrient Initiative, World Bank, United Nations Childrens' Fund, and the World Health Organization. Instead, this volume examines key elements in the design and implementation of micronutrient interventions, including such issues as: The importance of iron, vitamin A, and iodine to health. Populations at risk for micronutrient deficiency. Options for successful interventions and their cost. The feasibility of involving societal sectors in the planning and implementation of interventions. Characteristics of successful interventions. The book also contains three in-depth background papers that address the prevention of deficiencies of iron, vitamin A, and iodine.

Author : Mendel Friedman
Publisher : Springer Science & Business Media
Page : 686 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468409437

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Protein-Metal Interactions by Mendel Friedman Pdf

Metal ions and proteins are ubiquitous. Therefore, not surprisingly, new protein-metal interactions continue to be dis covered, and their importance is increasingly recognized in both physical and life sciences. Because the subject matter is so broad and affects so many disciplines, in organizing this Symposium, I sought participation of speakers with the broadest possible range of interests. Twenty-two accepted my invitation. To supplement the verbal presentations, the Proceedings include five closely re lated invited contributions. The ideas expressed are those of the various authors and are not necessarily approved or rejected by any agency of the United States Government. No official recommendation concerning the sub ject matter or products discussed is implied in this book. This book encompasses many aspects of this multifaceted field. Topics covered represent biochemical, immunochemical, bioorganic, biophysical, metabolic, nutritional, medical, physiological, toxi cological, environmental, textile, and analytical interests. The discoveries and developments in any of these areas inevitably illumine others. I feel that a main objective of this Symposium, bringing together scientists with widely varied experiences yet with common interests in protein-metal interactions, so that new understanding and new ideas would result has been realized. I hope that the reader enjoys and benefits from reading about the fascinat ing interactions of metal ions and proteins as much as I did.

Author : Alexandre Mebazaa,Mihai Gheorghiade,Faiez Zannad,Joseph E. Parrillo
Publisher : Springer Science & Business Media
Page : 931 pages
File Size : 47,7 Mb
Release : 2009-12-24
Category : Medical
ISBN : 9781846287824

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Acute Heart Failure by Alexandre Mebazaa,Mihai Gheorghiade,Faiez Zannad,Joseph E. Parrillo Pdf

For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.

Author : Surya Nandan Meena,Milind Naik
Publisher : Academic Press
Page : 580 pages
File Size : 55,5 Mb
Release : 2019-05-17
Category : Science
ISBN : 9780128174982

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Advances in Biological Science Research by Surya Nandan Meena,Milind Naik Pdf

Advances in Biological Science Research: A Practical Approach provides discussions on diverse research topics and methods in the biological sciences in a single platform. This book provides the latest technologies, advanced methods, and untapped research areas involved in diverse fields of biological science research such as bioinformatics, proteomics, microbiology, medicinal chemistry, and marine science. Each chapter is written by renowned researchers in their respective fields of biosciences and includes future advancements in life science research. Discusses various research topics and methods in the biological sciences in a single platform Comprises the latest updates in advanced research techniques, protocols, and methods in biological sciences Incorporates the fundamentals, advanced instruments, and applications of life science experiments Offers troubleshooting for many common problems faced while performing research experiments

Author : U.S. Atomic Energy Commission. Division of Biology and Medicine
Publisher : Unknown
Page : 524 pages
File Size : 53,6 Mb
Release : 1968
Category : Biology
ISBN : UOM:39015095053438

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Research and Development in Progress by U.S. Atomic Energy Commission. Division of Biology and Medicine Pdf

Author : John B. Mason,International Development Research Centre (Canada),Micronutrient Initiative (Organization)
Publisher : Initiative Pour Les mircrnutriments
Page : 116 pages
File Size : 42,8 Mb
Release : 2001
Category : Social Science
ISBN : 1894217187

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The Micronutrient Report by John B. Mason,International Development Research Centre (Canada),Micronutrient Initiative (Organization) Pdf

Micronutrient Report: Current Progress and Trends in the Control

Author : Nan Lin Wang,Hideo Hosono,Pengcheng Dai
Publisher : CRC Press
Page : 562 pages
File Size : 53,6 Mb
Release : 2012-11-19
Category : Science
ISBN : 9789814303231

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Iron-based Superconductors by Nan Lin Wang,Hideo Hosono,Pengcheng Dai Pdf

From fundamental physics point of view, iron-based superconductors have properties that are more amenable to band structural calculations. This book reviews the progress made in this fascinating field. With contributions from leading experts, the book provides a guide to understanding materials, physical properties, and superconductivity mechanism aspects, and is important for students and beginners to have an overall view of the recent progress in this active field.

Author : Yan-Zhong Chang
Publisher : Springer Nature
Page : 194 pages
File Size : 44,9 Mb
Release : 2019-08-27
Category : Medical
ISBN : 9789811395895

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Brain Iron Metabolism and CNS Diseases by Yan-Zhong Chang Pdf

This book focuses on advances in our understanding of the regulatory mechanisms of brain iron uptake, iron homeostasis and iron metabolism in the pathophysiology and pharmacology of CNS disease models. Dysregulation of brain iron homeostasis can lead to severe pathological changes in the neural system. Iron deficiency can slow down the development of the neural system and cause language and motion disorders, while iron overload is closely related to neurodegenerative diseases. Although some current books include chapters on iron metabolism and certain neurodegenerative diseases, this is the first systematic summary of the latest discoveries regarding brain iron metabolism and CNS diseases. By providing novel and thought-provoking insights into the mechanisms and physiological significance of brain iron metabolism and related diseases, the book stimulates further new research directions. It helps graduate students and researchers gain an overall picture of brain iron metabolism and the pathogenesis of neurodegenerative diseases, and also offers pharmaceutical companies inspiration for new treatment strategies for CNS diseases.