Protein Adaptations And Signal Transduction

Author : K.B. Storey,J.M. Storey
Publisher : Elsevier
Page : 312 pages
File Size : 44,8 Mb
Release : 2001-07-19
Category : Science
ISBN : 0080539963

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Protein Adaptations and Signal Transduction by K.B. Storey,J.M. Storey Pdf

This volume of Cell and Molecular Responses to Stress has two broad themes: an examination of selected protein adaptations that support stress tolerance and an analysis of signal transduction systems, those critical links between the perception of stress and the activation of the coordinated metabolic responses that ensure survival. Several chapters deal with adaptive responses to environmental cold temperature and highlight novel advances in mammalian hibernation, low temperature enzyme function, cold-shock and antifreeze proteins, and freezing survival. Other chapters stretch out to explore biochemical responses to diverse stresses including water stress, mechanical stress, nutrient availability, oxygen limitation and oxidative stress. The integral roles of protein kinases, transcription factors, oxygen free radicals, and oxygen-sensitive ion channels in the detection and mediation of stress responses are explored. The multiplicity of responses is emphasized and shows us the vast potential of cells and organisms to respond to innumerable stresses, great and small, and the regulatory principles and mechanisms that are used to allow life to adapt and endure in every environment on Earth. Featuring: A discussion of new advances in understanding protein adaptations that support organismal survival of stress. State-of-the-art analysis of key components of cellular signal transduction pathways including protein kinases and calcium and the control, integration and action of signal transduction pathways in response to stresses including mechanical stress, nutrient availability, oxidative stress.

Author : J.M. Storey,K.B. Storey
Publisher : Elsevier
Page : 357 pages
File Size : 42,7 Mb
Release : 2002-09-16
Category : Science
ISBN : 9780080541075

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Sensing, Signaling and Cell Adaptation by J.M. Storey,K.B. Storey Pdf

In this volume of Cell and Molecular Responses to Stress articles provide up-to-date information on key areas of signal sensing (sensing of pain, heat, cold, light, infrared radiation), molecules involved in the intracellular transmission of these signals, metabolic responses to stress including changes in gene expression and production of specialized proteins that aid cell responses to factors including interrupted blood supply (ischemia), oxygen limitation (hypoxia/anoxia), freezing and dehydration, amino acid limitation, radiation and processing drugs. There are chapters which also provide insights into new technologies (such as cDNA arrays), analysis of metabolic control theory (a key method for analysing stress effects on cells), and examine how enzymes evolve in the face of stress.

Author : Friedrich Marks,Ursula Klingmüller,Karin Müller-Decker
Publisher : Garland Science
Page : 640 pages
File Size : 48,5 Mb
Release : 2017-05-17
Category : Medical
ISBN : 9781351677226

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Cellular Signal Processing by Friedrich Marks,Ursula Klingmüller,Karin Müller-Decker Pdf

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Author : Bastien D. Gomperts,ljsbrand M. Kramer,Peter E.R. Tatham
Publisher : Gulf Professional Publishing
Page : 420 pages
File Size : 51,9 Mb
Release : 2002-03-08
Category : Science
ISBN : 9780080541181

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Signal Transduction by Bastien D. Gomperts,ljsbrand M. Kramer,Peter E.R. Tatham Pdf

Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine Extensive conceptual colour artwork assists with the comprehension of key topics Extensive referencing provides an invaluable link to the core and historical literature Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 48,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Anthony J. Pawson
Publisher : Springer
Page : 368 pages
File Size : 51,7 Mb
Release : 2011-12-25
Category : Science
ISBN : 3642804829

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Protein Modules in Signal Transduction by Anthony J. Pawson Pdf

Author : Neil Spurway,Henning Wackerhage
Publisher : Elsevier Health Sciences
Page : 285 pages
File Size : 54,7 Mb
Release : 2006-01-01
Category : Medical
ISBN : 9780443100772

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Genetics and Molecular Biology of Muscle Adaptation by Neil Spurway,Henning Wackerhage Pdf

This title is directed primarily towards health care professionals outside of the United States. It starts with the origin of life and ends with the mechanisms that make muscles adapt to different forms of training. In between, it considers how evidence has been obtained about the extent of genetic influence on human capacities, how muscles and their fibres are studied for general properties and individual differences, and how molecular biological techniques have been combined with physiological ones to produce the new discipline of molecular exercise physiology. This is the first book on such topics written specifically for modules in exercise and sport science at final year Hons BSc and taught MSc levels.

Author : Ayse Basak Engin,Atilla Engin
Publisher : Springer Nature
Page : 415 pages
File Size : 43,7 Mb
Release : 2021-02-04
Category : Medical
ISBN : 9783030498443

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Protein Kinase-mediated Decisions Between Life and Death by Ayse Basak Engin,Atilla Engin Pdf

Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information. Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author : Gerhard Krauss
Publisher : John Wiley & Sons
Page : 558 pages
File Size : 54,6 Mb
Release : 2006-03-06
Category : Science
ISBN : 9783527605767

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Biochemistry of Signal Transduction and Regulation by Gerhard Krauss Pdf

This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)

Author : Radhouane Chaffai
Publisher : Springer Nature
Page : 536 pages
File Size : 51,5 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9789819706723

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Plant Adaptation to Abiotic Stress: From Signaling Pathways and Microbiomes to Molecular Mechanisms by Radhouane Chaffai Pdf

Author : Peter W. Hochachka,George N. Somero
Publisher : Oxford University Press
Page : 482 pages
File Size : 51,8 Mb
Release : 2002-01-17
Category : Science
ISBN : 0195353676

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Biochemical Adaptation by Peter W. Hochachka,George N. Somero Pdf

The study of biochemical adaption provides fascinating insights into how organisms "work" and how they evolve to sustain physiological function under a vast array of environmental conditions. This book describes how the abilities of organisms to thrive in widely different environments derive from two fundamental classes of biochemical adaptions: modifications of core biochemical processes that allow a common set of physiological functions to be conserved, and "inventions" of new biochemical traits that allow entry into novel habitats. Biochemical Adaptation: Mechanisms and Process in Physiological Evolution asks two primary questions. First, how have the core biochemical systems found in all species been adaptively modified to allow the same fundamental types of physiological processes to be sustained throughout the wide range of habitat conditions found in the biosphere? Second, through what types of genetic and biochemical processes have new physiological functions been fabricated? The primary audience for this book is faculty, senior undergraduates, and graduate students in environmental biology, comparative physiology, and marine biology. Other likely readers include workers in governmental laboratories concerned with environmental issues, medical students interested in some elements of the book, and medical researchers.

Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
Page : 502 pages
File Size : 45,8 Mb
Release : 2006-09-29
Category : Medical
ISBN : 9781420005844

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TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by Wolfgang B. Liedtke, MD, PH.D. Pdf

Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Author : Dipak K. Das
Publisher : Springer Science & Business Media
Page : 177 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461550976

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Stress Adaptation, Prophylaxis and Treatment by Dipak K. Das Pdf

Stress reaction is likely to play a crucial role in a variety of degenerative diseases including cancer and cardiovascular diseases. The process of stress adaptation may appear to be simple, but in reality this is a very complex process and we are only beginning to understand the mechanism of adaptation. In January, 1998, scientists from around the world assembled to discuss the potential applicability of the concept of stress adaptation in the clinical arena. This volume contains original research papers presented on this subject during the conference Stress Adaptation, Prophylaxis and Treatment held in Calcutta, India, and serves as an up-to-date source of information for scientists, as well as clinicians interested in applying the concept of stress adaptation to the cure of diseases.

Author : Bruce Spiegelman
Publisher : Springer
Page : 108 pages
File Size : 51,7 Mb
Release : 2018-03-07
Category : Science
ISBN : 9783319727905

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Hormones, Metabolism and the Benefits of Exercise by Bruce Spiegelman Pdf

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.

Author : Adam P Sharples,Henning Wackerhage,James P Morton
Publisher : Routledge
Page : 549 pages
File Size : 54,5 Mb
Release : 2022-05-11
Category : Science
ISBN : 9781351617000

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Molecular Exercise Physiology by Adam P Sharples,Henning Wackerhage,James P Morton Pdf

Fully revised and expanded, the second edition of Molecular Exercise Physiology offers a student-friendly introduction. It introduces a history documenting the emergence of molecular biology techniques to investigate exercise physiology, the methodology used, exercise genetics and epigenetics, and the molecular mechanisms that lead to adaptation after different types of exercise, with explicit links to outcomes in sport performance, nutrition, physical activity and clinical exercise. Structured around key topics in sport and exercise science and featuring contributions from pioneering scientists, such as Nobel Prize winners, this edition includes new chapters based on cutting-edge research in epigenetics and muscle memory, satellite cells, exercise in cancer, at altitude, and in hot and cold climates. Chapters include learning objectives, structured guides to further reading, review questions, overviews of work by key researchers and box discussions from important pioneers in the field, making it a complete resource for any molecular exercise physiology course. The book includes cell and molecular biology laboratory methods for dissertation and research projects in molecular exercise physiology and muscle physiology. This book is essential reading for upper-level undergraduate or postgraduate courses in cellular and molecular exercise physiology and muscle physiology. It is a valuable resource for any student with an advanced interest in exercise physiology in both sport performance and clinical settings.