Rare Earth Element Biochemistry Characterization And Applications Of Lanthanide Binding Biomolecules

Author : Anonim
Publisher : Academic Press
Page : 414 pages
File Size : 44,6 Mb
Release : 2021-04-20
Category : Science
ISBN : 9780323910866

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Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules by Anonim Pdf

Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules, Volume 651 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules, Determination of affinities of lanthanide-binding proteins using chelator-buffered titrations, Electron Paramagnetic Resonance of Lanthanides, Characterization of lanthanoid binding proteins using NMR spectroscopy, Macromolecular crystallography for f-element complex characterization, Infrared spectroscopy probes ion binding geometries, Predicting lanthanide coordination structures in solution with molecular simulation, and much more. Additional sections cover the Characteristics of Gd(III) spin labels for the study of protein conformations, Lanthanide-based resonance energy transfer biosensors for live-cell applications, Yttrium-86 PET imaging, Aqueous Chemistry of the Smallest Rare Earth: Comprehensive Characterization of Radioactive and Non-radioactive Scandium Complexes for Biological Applications, and In vitro selection and application of lanthanide-dependent DNAzymes. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Author : Anonim
Publisher : Academic Press
Page : 276 pages
File Size : 50,7 Mb
Release : 2021-04-16
Category : Science
ISBN : 9780128238578

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Rare-earth element biochemistry: Methanol dehydrogenases and lanthanide biology by Anonim Pdf

Methods in Enzymology, Volume 650 continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Biophysical methods to study lanthanide-protein interactions, Genetically encoded sensors to study lanthanide biology, Spectrophotometric methods to determine the stability constants of lanthanide-macromolecule complexes, Lanthanide-based probes for amino acid modifications, In vitro selection and application of lanthanide-dependent DNAzymes, LRET biosensors for imaging protein interactions in living cells, Synthetic Modeling of the Structure and Function of the Lanthanide-Dependent, MDH Cofactor, EPR spectroscopy of lanthanides, Macromolecular crystallography for f-element complex characterization, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Author : Tatyana Polenova,Caitlin M. Quinn,Angela M. Gronenborn
Publisher : Royal Society of Chemistry
Page : 404 pages
File Size : 43,7 Mb
Release : 2023-12-08
Category : Science
ISBN : 9781839161834

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Integrated Structural Biology by Tatyana Polenova,Caitlin M. Quinn,Angela M. Gronenborn Pdf

This book provides an overview of the contemporary integrated biology approaches for solving structures and understanding mechanisms of complex biological systems.

Author : Paul Hodgkinson,Josep Sauri
Publisher : Royal Society of Chemistry
Page : 331 pages
File Size : 48,6 Mb
Release : 2022-11-14
Category : Science
ISBN : 9781839167065

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Nuclear Magnetic Resonance: Volume 48 by Paul Hodgkinson,Josep Sauri Pdf

Applications of nuclear magnetic resonance span a wide range of scientific disciplines, from chemistry and physics to medicine. For those wanting to become acquainted with NMR or seasoned practitioners, this is a valuable source of current methods and applications.

Author : The Nuclear Magnetic Resonance Society of Japan
Publisher : Springer
Page : 636 pages
File Size : 51,9 Mb
Release : 2017-11-23
Category : Science
ISBN : 9789811059667

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Experimental Approaches of NMR Spectroscopy by The Nuclear Magnetic Resonance Society of Japan Pdf

This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

Author : Anonim
Publisher : Academic Press
Page : 684 pages
File Size : 43,8 Mb
Release : 2016-08-27
Category : Medical
ISBN : 9780128054345

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Peptide, Protein and Enzyme Design by Anonim Pdf

De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction. Continues the legacy of this premier serial with quality chapters on de novo enzyme design Represents the newest volume in the Methods in Enzymology series, providing premier, quality chapters authored by leaders in the field Ideal reference for those interested in the study of enzyme design that looks at both structure and mechanism

Author : Wilfred Raymond Hagen
Publisher : CRC Press
Page : 248 pages
File Size : 42,8 Mb
Release : 2008-12-22
Category : Science
ISBN : 1420059580

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Biomolecular EPR Spectroscopy by Wilfred Raymond Hagen Pdf

Comprehensive, Up-to-Date Coverage of Spectroscopy Theory and its Applications to Biological Systems Although a multitude of books have been published about spectroscopy, most of them only occasionally refer to biological systems and the specific problems of biomolecular EPR (bioEPR). Biomolecular EPR Spectroscopy provides a practical introduction to bioEPR and demonstrates how this remarkable tool allows researchers to delve into the structural, functional, and analytical analysis of paramagnetic molecules found in the biochemistry of all species on the planet. A Must-Have Reference in an Intrinsically Multidisciplinary Field This authoritative reference seamlessly covers all important bioEPR applications, including low-spin and high-spin metalloproteins, spin traps and spin lables, interaction between active sites, and redox systems. It is loaded with practical tricks as well as do’s and don’ts that are based on the author’s 30 years of experience in the field. The book also comes with an unprecedented set of supporting software designed with simple graphical user interfaces that allow readers to tackle problems they will likely encounter when engaged in spectral analysis. Breaking with convention, the book broaches quantum mechanics from the perspective of biological relevance, emphasizing low-symmetry systems. This is a necessary approach since paramagnets in biomolecules typically have no symmetry. Where key topics related to quantum mechanics are addressed, the book offers a rigorous treatment in a style that is quick-to-grasp for the non expert. Biomolecular EPR Spectroscopy is a practical, all-inclusive reference sure to become the industry standard.

Author : Kenneth Kam-Wing Lo
Publisher : Springer
Page : 260 pages
File Size : 45,6 Mb
Release : 2015-06-30
Category : Science
ISBN : 9783662467183

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Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents by Kenneth Kam-Wing Lo Pdf

The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors. Readership: research scientists at universities or in industry, graduate students Special offer For all customers who have a standing order to the print version of Structure and Bonding, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink.

Author : Greg T. Hermanson
Publisher : Academic Press
Page : 1233 pages
File Size : 46,5 Mb
Release : 2010-07-26
Category : Science
ISBN : 9780080568720

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Bioconjugate Techniques by Greg T. Hermanson Pdf

Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions

Author : Radislav A. Potyrailo,Vladimir M. Mirsky
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 48,5 Mb
Release : 2009-03-21
Category : Science
ISBN : 9780387737133

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Combinatorial Methods for Chemical and Biological Sensors by Radislav A. Potyrailo,Vladimir M. Mirsky Pdf

Chemical sensors are in high demand for applications as varied as water pollution detection, medical diagnostics, and battlefield air analysis. Designing the next generation of sensors requires an interdisciplinary approach. The book provides a critical analysis of new opportunities in sensor materials research that have been opened up with the use of combinatorial and high-throughput technologies, with emphasis on experimental techniques. For a view of component selection with a more computational perspective, readers may refer to the complementary volume of Integrated Analytical Systems edited by M. Ryan et al., entitled “Computational Methods for Sensor Material Selection”.

Author : Hans-Curt Flemming,Dr Thomas R. Neu,Dr Jost Wingender
Publisher : IWA Publishing
Page : 336 pages
File Size : 53,8 Mb
Release : 2016-09-15
Category : Science
ISBN : 9781780407418

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The Perfect Slime by Hans-Curt Flemming,Dr Thomas R. Neu,Dr Jost Wingender Pdf

The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?

Author : Giovanni Benelli
Publisher : MDPI
Page : 224 pages
File Size : 42,9 Mb
Release : 2019-11-18
Category : Science
ISBN : 9783039217861

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Green Synthesis of Nanomaterials by Giovanni Benelli Pdf

Nanomaterials possess astonishing physical and chemical properties. They play a key role in the development of novel and effective drugs, catalysts, sensors, and pesticides, to cite just a few examples. Notably, the synthesis of nanomaterials is usually achieved with chemical and physical methods needing the use of extremely toxic chemicals or high-energy inputs. To move towards more eco-friendly processes, researchers have recently focused on so-called “green synthesis”, where microbial, animal-, and plant-borne compounds can be used as cheap reducing and stabilizing agents to fabricate nanomaterials. Green synthesis routes are cheap, environmentally sustainable, and can lead to the fabrication of nano-objects with controlled sizes and shapes—two key features determining their bioactivity. However, real-world applications of green-fabricated nanomaterials are largely unexplored. Besides, what do we really know about their non-target toxicity? Which are their main modes of action? What is their possible fate in the environment? In this framework, the present Special Issue will include articles by expert authorities on nanomaterials synthesis and applications. Special emphasis will be placed on their impact on the environment and long-term toxicity.

Author : C. Anthony
Publisher : Unknown
Page : 458 pages
File Size : 44,8 Mb
Release : 1982
Category : Science
ISBN : UOM:39015004440833

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The Biochemistry of Methylotrophs by C. Anthony Pdf

Author : Anil Mahapatro,Ankur S. Kulshrestha
Publisher : American Chemical Society
Page : 442 pages
File Size : 45,8 Mb
Release : 2008-04-17
Category : Science
ISBN : UOM:39015075620875

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Polymers for Biomedical Applications by Anil Mahapatro,Ankur S. Kulshrestha Pdf

Research on applications of polymers for biomedical applications has increased dramatically to find improved medical plastics for this rapidly evolving field. This book brings together various aspects of recent research and developments within academia and industry related to polymers for biomedical applications.

Author : Nicholas V. Hud
Publisher : Royal Society of Chemistry
Page : 449 pages
File Size : 40,9 Mb
Release : 2009
Category : Science
ISBN : 9780854041954

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Nucleic Acid-metal Ion Interactions by Nicholas V. Hud Pdf

Provides a perspective on nucleic acid-metal ion interactions with an emphasis on experimental biophysical studies which will prove indispensable to biophysicists and molecular biologists.