Replication

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 51,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Jill Williamson
Publisher : Zonderkidz
Page : 399 pages
File Size : 41,6 Mb
Release : 2012-01-03
Category : Juvenile Fiction
ISBN : 9780310727590

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Replication by Jill Williamson Pdf

A girl discovers her geneticist father is covering up multiple secrets—all of which are named Jason. Jason 3:3—known as Martyr—always believed his life had purpose. As one of the hundreds of clones living in a closed-off underground facility beneath an Alaskan farm, he has been told his genetics hold the key to saving humanity from an airborne pandemic aboveground, and his purpose will be filled on his upcoming eighteenth birthday. The problem is no such pandemic exists. Unaware of the truth, Martyr wishes for one glimpse of the sky before his expiration date arrives. His escape leads him to the home of one of the scientists, and to Abby Goyer. As she helps Martyr, she can’t help but notice his uncanny resemblance to the high school quarterback. Abby soon uncovers the dark truth behind Jason Farms and her dad’s work, and decides to show Martyr his true value and worth. As Martyr learns the truth behind his existence, he must decide if his God-given purpose is connected to the farm, or if it rests in a life with Abby.

Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Page : 618 pages
File Size : 50,9 Mb
Release : 2018-01-07
Category : Science
ISBN : 9888407457

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Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Author : Hans-Jürgen Schönig
Publisher : Packt Publishing Ltd
Page : 322 pages
File Size : 50,6 Mb
Release : 2015-07-28
Category : Computers
ISBN : 9781783988549

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PostgreSQL Replication by Hans-Jürgen Schönig Pdf

PostgreSQL offers a comprehensive set of replication related features. Unleashing the power of PostgreSQL provides you with countless opportunities and a competitive advantage over other database systems. This book will guide you through the most important concepts of PostgreSQL replication. It contains all the information you need to design and operate replicated setups. Beginning by giving you an understanding of replication concepts, the PostgreSQL transaction log, and Point-in-time Recovery, we gradually move on to setting up asynchronous and synchronous replication. Next up, you will learn to monitor a PostgreSQL cluster setup, deal with monitoring tools, and then move on to understanding Linux High Availability. Further, we explore widely-used tools such as Slony, SkyTools, Postgres-XC, and walbouncer, and set up PL/Proxy. Finally, you'll get acquainted with the new technology of BDR, which allows bidirectional replication in PostgreSQL.

Author : Bernadette Charron-Bost,Fernando Pedone,Andre Schiper
Publisher : Springer Science & Business Media
Page : 298 pages
File Size : 55,9 Mb
Release : 2010-03-02
Category : Computers
ISBN : 9783642112935

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Replication by Bernadette Charron-Bost,Fernando Pedone,Andre Schiper Pdf

Consistency models for replicated data /Alan D. Fekete and Krithi Ramamritham --Replication techniques for availability /Robbert van Renesse and Rachid Guerraoui --Modular approach to replication for availability /Fernando Pedone and André Schiper --Stumbling over consensus research: misunderstandings and issues /Marcos K. Aguilera --Replicating for performance: case studies /Maarten van Steen and Guillaume Pierre --A history of the virtual synchrony replication model /Ken Birman --From viewstamped replication to byzantine fault tolerance /Barbara Liskov --Implementing trustworthy services using replicated state machines /Fred B. Schneider and Lidong Zhou --State machine replication with Byzantine faults /Christian Cachin --Selected results from the latest decade of quorum systems research /Michael G. Merideth and Michael K. Reiter --From object replication to database replication /Fernando Pedone and André Schiper --Database replication: a tutorial /Dettina Kemme, Ricardo Jiménez-Peris, Marta Patiño-Martínez, and Gustavo Alonso --Practical database replication /Alfrânio Correia Jr. ... [et al.].

Author : Arthur Kornberg,Tania A. Baker
Publisher : University Science Books
Page : 964 pages
File Size : 45,8 Mb
Release : 2005-06-24
Category : Science
ISBN : 1891389440

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DNA Replication by Arthur Kornberg,Tania A. Baker Pdf

DNA Replication, second edition, a classic of modernscience, is now back in print in a paperback edition. Kornberg and Baker'sinsightful coverage of DNA replication and related cellular processes have madethis the standard reference in the field.

Author : Robert M. Brosh Jr.
Publisher : MDPI
Page : 368 pages
File Size : 52,8 Mb
Release : 2019-08-27
Category : Science
ISBN : 9783039213894

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DNA Replication Stress by Robert M. Brosh Jr. Pdf

This Special Issue of International Journal of Molecular Sciences (IJMS) is dedicated to the mechanisms mediated at the molecular and cellular levels in response to adverse genomic perturbations and DNA replication stress. The relevant proteins and processes play paramount roles in nucleic acid transactions to maintain genomic stability and cellular homeostasis. A total of 18 articles are presented which encompass a broad range of highly relevant topics in genome biology. These include replication fork dynamics, DNA repair processes, DNA damage signaling and cell cycle control, cancer biology, epigenetics, cellular senescence, neurodegeneration, and aging. As Guest Editor for this IJMS

Author : Bagai,Saroj Kapoor Bagai,Jagan Bandi Reddy,Jeff Tallman
Publisher : Jones & Bartlett Publishers
Page : 651 pages
File Size : 50,9 Mb
Release : 2008-12-08
Category : Computers
ISBN : 9781449613174

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Sybase 15.0 Replication Server Administration by Bagai,Saroj Kapoor Bagai,Jagan Bandi Reddy,Jeff Tallman Pdf

Sybase 15 Replication Server Administration addresses the needs of a wide range of database professionals, explaining to both beginners and experts how to administer Sybase’s newest Replication Server release. This book examines all the knowledge, background information, and conceptual frameworks needed in order to get started on installing and administering Sybase Replication Server, and explores the world of contemporary cross-platform compatible Sybase Replication Server administration. Learn how to replicate business-critical data; configure database connections and routes; manage replicated tables, stored procedures, and subscriptions; set up a warm standby system; monitor replication performance and tune the database system; provide up-to-the-minute high availability of data; recover from failures and prevent data loss; troubleshoot the replication system.

Author : Proceedings of the National Academy of Sciences
Publisher : National Academies Press
Page : 303 pages
File Size : 52,7 Mb
Release : 2002-09-18
Category : Science
ISBN : 9780309074247

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Links Between Recombination and Replication by Proceedings of the National Academy of Sciences Pdf

There has been a sea change in how we view genetic recombination. When germ cells are produced in higher organisms, genetic recombination assures the proper segregation of like chromosomes. In the course of that process, called meiosis, recombination not only assures segregation of one chromosome of each type to progeny germ cells, but also further shuffles the genetic deck, contributing to the unique inheritance of individuals. In a nutshell, that is the classical view of recombination. We have also known for many years that in bacteria recombination plays a role in horizontal gene transfer and in replication itself, the latter by establishing some of the replication forks that are the structural scaffolds for copying DNA. In recent years, however, we have become increasingly aware that replication, which normally starts without any help from recombination, is a vulnerable process that frequently leads to broken DNA. The enzymes of recombination play a vital role in the repair of those breaks. The recombination enzymes can function via several different pathways that mediate the repair of breaks, as well as restoration of replication forks that are stalled by other kinds of damage to DNA. Thus, to the classical view of recombination as an engine of inheritance we must add the view of recombination as a vital housekeeping function that repairs breaks suffered in the course of replication. We have also known for many years that genomic instability--including mutations, chromosomal rearrangements, and aneuploidy--is a hallmark of cancer cells. Although genomic instability has many contributing causes, including faulty replication, there are many indications that recombination, faulty or not, contributes to genome instability and cancer as well. The (Nas colloquium) Links Between Recombination and Replication: Vital Roles of Recombination was convened to broaden awareness of this evolving area of research. Papers generated by this colloquium are published here. To encourage the desired interactions of specialists, we invited some contributions that deal only with recombination or replication in addition to contributions on the central thesis of functional links between recombination and replication. To aid the nonspecialist and specialist alike, we open the set of papers with a historical overview by Michael Cox and we close the set with a commentary on the meeting and the field by Andrei Kuzminov.

Author : Daniel L. Kaplan
Publisher : Springer
Page : 563 pages
File Size : 40,5 Mb
Release : 2016-02-11
Category : Medical
ISBN : 9783319246963

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The Initiation of DNA Replication in Eukaryotes by Daniel L. Kaplan Pdf

​Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of replication initiation is of paramount importance, because once the cell is committed to replicate DNA, it must finish this process. A great deal of progress has been made in understanding how DNA replication is initiated in eukaryotic cells in the past ten years, but this is the first one-source book on these findings. The Initiation of DNA Replication in Eukaryotes will focus on how DNA replication is initiated in eukaryotic cells. While the concept of replication initiation is simple, its elaborate regulation and integration with other cell processes results in a high level of complexity. This book will cover how the position of replication initiation is chosen, how replication initiation is integrated with the phases of the cell cycle, and how it is regulated in the case of damage to DNA. It is the cellular protein machinery that enables replication initiation to be activated and regulated. We now have an in-depth understanding of how cellular proteins work together to start DNA replication, and this new resource will reveal a mechanistic description of DNA replication initiation as well.

Author : Patrick Hughes,Ellen Fanning,Masamichi Kohiyama
Publisher : Springer Science & Business Media
Page : 429 pages
File Size : 46,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642769887

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DNA Replication: The Regulatory Mechanisms by Patrick Hughes,Ellen Fanning,Masamichi Kohiyama Pdf

DNA replication is a key event in the cell cycle. Although our knowledge is far from complete and many elusive regulatory mechanisms still remain beyondour grasp, many enzymes and a multiplicity of biochemical mechanisms involved have been discovered. Recent findings in E. coli have confirmed and yet surpassed the original hypothesis of F. Jacob. In yeast and higher eucaryotes, the apparent redundancy in putative origins and initiators has made an estimation of the importance of each identified element difficult to access. In spite of well established methodologies - which are also described in the book - the origin identification in mammalian chromosomes is still a controversial subject. On the other hand, considerable advances have been made in our understanding of virus DNA replication and this continues to deepen and broaden our understanding of the controls of cellular DNA replication.

Author : Lynne S Cox
Publisher : Royal Society of Chemistry
Page : 315 pages
File Size : 46,9 Mb
Release : 2009-10-31
Category : Science
ISBN : 9781847559852

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Molecular Themes in DNA Replication by Lynne S Cox Pdf

DNA replication, the process of copying one double stranded DNA molecule to form two identical copies, is highly conserved at the mechanistic level across evolution. Interesting in its own right as a fascinating feat of biochemical regulation and coordination, DNA replication is at the heart of modern advances in molecular biology. An understanding of the process at both the biological and chemical level is essential to developing new techniques in molecular biology. Insights into the process at the molecular level provide opportunities to modulate and intervene in replication. Rapidly dividing cells need to replicate their DNA prior to division, and targeting components of the replication process is a potentially powerful strategy in cancer treatment. Conversely, ageing may be associated with loss of replication activity and restoring it to cells may moderate some of the diseases associated with old age. Replication is, therefore, fundamental to a huge range of molecular biological and biochemical applications, and provides many potential targets for drug design. The fast pace of replication research, particularly in providing new structural insights, has outdated the majority of available texts. This learned, yet accessible, book contains the latest research written by those conducting it. It examines conserved themes providing a biological background for biochemical, chemical and pharmaceutical studies of this huge and exciting field. Rather than simply "itemising" the replication steps and the proteins involved, replication is tackled from a novel perspective. The book provides logical groupings of processes based upon biochemical similarities. The emphasis on mechanisms and the relationship between structure and function targets the chapters towards biochemists and biological chemists as well as molecular and cell biologists. The book highlights new insights into the replication process, from the assembly of pre-replication complexes, through polymerisation mechanisms, to considering replication in the context of chromatin and chromosomes. It also covers mitochondrial DNA replication, and includes archaeal paradigms, which are proving increasingly relevant to the study of replication in higher eukaryotes. Exciting potential drug targets in DNA replication are discussed, particularly in the context of treating malaria and cancer.

Author : Chris Bulmer,Chris Canto,Daniel Dent,Bill Passingham,Nolan Rogers,David Seager,IBM Redbooks
Publisher : IBM Redbooks
Page : 78 pages
File Size : 43,6 Mb
Release : 2023-02-14
Category : Computers
ISBN : 9780738461038

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Policy-Based Replication with IBM Storage FlashSystem, IBM SAN Volume Controller and IBM Storage Virtualize by Chris Bulmer,Chris Canto,Daniel Dent,Bill Passingham,Nolan Rogers,David Seager,IBM Redbooks Pdf

Policy-based replication is the successor to Remote Copy for providing replication services for IBM Storage FlashSystem, IBM SAN Volume Controller, and IBM Storage Virtualize for version 8.5.2 and later. This new management model uses volume groups and replication policies to enable the system to automatically deploy and manage replication. This significantly simplifies the tasks that are associated with configuring, managing, and monitoring replication. Compared to Remote Copy, policy-based replication replicates data between systems with minimal overhead, significantly higher throughput, and reduced latency characteristics. This IBM Redpaper publication provides a broad understanding of policy-based replication and step-by-step implementation details. This paper is intended for use by pre-sales and post-sales technical support and storage administrators.

Author : Roger J. A. Grand,John J. Reynolds
Publisher : Garland Science
Page : 368 pages
File Size : 52,9 Mb
Release : 2018-09-03
Category : Science
ISBN : 9780429876547

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DNA Repair and Replication by Roger J. A. Grand,John J. Reynolds Pdf

DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease, with particular focus on both the causes and treatments which make use of DNA Damage Repair (DDR) pathways. Key Selling Features: Chapters written by leading researchers Includes description of replication processes, causes of damage, and methods of repair

Author : A. De Recondo
Publisher : Springer Science & Business Media
Page : 361 pages
File Size : 47,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468443974

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New Approaches in Eukaryotic DNA Replication by A. De Recondo Pdf

DNA replication in eukaryotes is an important field, particular ly because of its direct impact on the study of cancer. The under standing of molecular mechanisms of replication and their regulation should allow a better comprehension of the alterations that lead to the proliferation of tumor cells and to error-prone repair in cells exposed to radiation or chemical carcinogens. During the last several years, many enzymes and proteins which participate in replication of DNA in eukaryotic cells have been identified, isolated and characterized. New concepts in chromatin structure have refocused attention on the study of replication of DNA complexed with his tones and non-histone chromosomal proteins. However, progress has been noticeably slower than for prokaryotes, essentially because of the difficulty in genetic analysis of eukaryo tic DNA replication. In June 1980, a workshop was organized in Cargese, Corsica (France) to facilitate exchanges of information between workers spe cializing in prokaryotes and those specializing in eukaryotes, and to allow discussion of new experimental approaches. With this in mind, special interest has been taken in the origin and termination of chromosome cycles and how they are controlled.