Systemic Silencing

Author : Katharine E. McGregor
Publisher : University of Wisconsin Pres
Page : 340 pages
File Size : 48,5 Mb
Release : 2023-08-29
Category : History
ISBN : 9780299344207

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Systemic Silencing by Katharine E. McGregor Pdf

The system of prostitution imposed and enforced by the Japanese military during its wartime occupation of several countries in East and Southeast Asia is today well-known and uniformly condemned. Transnational activist movements have sought to recognize and redress survivors of this World War II-era system, euphemistically known as “comfort women,” for decades, with a major wave beginning in the 1990s. However, Indonesian survivors, and even the system’s history in Indonesia to begin with, have largely been sidelined, even within the country itself. Here, Katharine E. McGregor not only untangles the history of the system during the war, but also unpacks the context surrounding the slow and faltering efforts to address it. With careful attention to the historical, social, and political conditions surrounding sexual violence in Indonesia, supported by exhaustive research and archival diligence, she uncovers a critical piece of Indonesian history and the ongoing efforts to bring it to the public eye. Critically, she establishes that the transnational part of activism surrounding victims of the system is both necessary and fraught, a complexity of geopolitics and international relationships on one hand and a question of personal networks, linguistic differences, and cultural challenges on the other.

Author : M.A. Matzke,A.J.M. Matzke
Publisher : Springer Science & Business Media
Page : 297 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401141833

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Plant Gene Silencing by M.A. Matzke,A.J.M. Matzke Pdf

This book is an up-to-date and comprehensive collection of reviews on various aspects of epigenetic gene silencing in plants. Research on this topic has undergone explosive growth during the past decade and has revealed novel features of gene regulation and plant defense responses that also apply to animals and fungi. Gene silencing is relevant for agricultural biotechnology because stable expression of transgenes is required for the successful commercialization of genetically engineered crops. The reviews have been written by distinguished authors who have made significant contributions to plant gene silencing research. This volume supersedes other books on gene silencing by focussing on plant systems, where many pioneering experiments have been performed, and by including the latest developments from top laboratories. The book is geared toward advanced students of genetics and plant sciences as well as applied and basic research scientists who work with transgenic organisms and epigenetic regulation of gene expression.

Author : Volker A. Erdmann,Jan Barciszewski
Publisher : Springer Science & Business Media
Page : 460 pages
File Size : 45,8 Mb
Release : 2010-09-02
Category : Medical
ISBN : 9783642121685

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RNA Technologies and Their Applications by Volker A. Erdmann,Jan Barciszewski Pdf

RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more than 15 years of extensive research in the field of RNA technologies, the first therapeutics are ready to reach the first patients. Thus we are witnessing the birth of a very exciting time in the development of molecular medicine, which will be based on the methods of RNA technologies. This volume is the first of a series. It covers various aspects of RNA interference and microRNAs, although antisense RNA applications, hammerhead ribozyme structure and function as well as non-coding RNAs are also discussed. The authors are internationally highly respected experts in the field of RNA technologies.

Author : Muhammad Sohail
Publisher : CRC Press
Page : 398 pages
File Size : 52,8 Mb
Release : 2004-08-27
Category : Medical
ISBN : 9780203489253

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Gene Silencing by RNA Interference by Muhammad Sohail Pdf

Maximizing the potential of RNA interference in functional genomics - as well as in the development of therapeutics - continues to be at the forefront of biomedical research. Unlike journal articles, Gene Silencing by RNA Interference: Technology and Application combines essential background to the RNAi field with practical techniques designed by r

Author : Wolfgang Nellen,Christian Hammann
Publisher : Springer Science & Business Media
Page : 220 pages
File Size : 48,6 Mb
Release : 2007-09-12
Category : Science
ISBN : 9783540281306

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Small RNAs: by Wolfgang Nellen,Christian Hammann Pdf

In recent years, the discovery of functional small RNAs has brought about an unprecedented revolution within the field of molecular biology. This volume describes strategies for the discovery and validation of small RNAs. It provides a snapshot of our current understanding of the different mechanisms triggered by small RNAs and the variations encountered in different organisms.

Author : Tuzun Sadik,Bent Elizabeth
Publisher : Springer Science & Business Media
Page : 538 pages
File Size : 44,6 Mb
Release : 2006-10-26
Category : Science
ISBN : 9780387232669

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Multigenic and Induced Systemic Resistance in Plants by Tuzun Sadik,Bent Elizabeth Pdf

Plants have developed very sophisticated mechanisms to combat pathogens and pestsusingtheleastamountofreservedorgeneratedenergypossible. Theydothis by activating major defense mechanisms after recognition of the organisms that are considered to be detrimental to their survival; therefore they have been able to exist on Earth longer than any other higher organisms. It has been known for the past century that plants carry genetic information for inherited resistance against many pathogenic organisms including fungi, bacteria, and viruses, and that the relationship between pathogenic organisms and hosts plants are rather complex and in some cases time dependent. This genetic information has been the basis for breeding for resistance that has been employed by plant breeders to develop better-yielding disease resistant varieties, some of which are still being cultivated. Single gene resistance is one type of resistance which has been extensively studied by many research groups all around the world using biotechnological methodologies that have been the subject of many books and journal articles; therefore, it is beyond the scope of this book. This type of resistance is very effective, although it can be overcome by the pressure of pathogenic organisms since it depends on interaction of a single elicitor molecule from the pathogen with a single receptor site in the host.

Author : R. K. Gaur,Yedidya Gafni,P. Sharma,V. K. Gupta
Publisher : CRC Press
Page : 380 pages
File Size : 49,6 Mb
Release : 2016-04-19
Category : Science
ISBN : 9781439873250

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RNAi Technology by R. K. Gaur,Yedidya Gafni,P. Sharma,V. K. Gupta Pdf

RNAi technology is used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. Introducing new technology in the study of RNA

Author : Esra Galun
Publisher : World Scientific
Page : 469 pages
File Size : 53,9 Mb
Release : 2005
Category : Science
ISBN : 9789812562067

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RNA Silencing by Esra Galun Pdf

This book focuses on an emerging, central issue in molecular genetics and the development of eukaryotes: the control of gene expression by small species of RNA. As an exciting new field of endeavor, it is the first book by a single author to deal comprehensively with RNA silencing.The book provides the historical background of the field preceding the seminal work by Fire and associates in 1998 on the impact of small double-stranded RNA on the expression of nematode genes, which is considered the beginning of RNA silencing research. RNA silencing is described in a wide range of plants and animals including protozoa, simple metazoa, insects, non-mammalian vertebrates, and mammals. In each case the experimental results are provided with the accompanying background and with illustrations. There is also an appendix on the prospective use of RNA silencing in gene therapy, which is intended as a guide for investigators wishing to explore this possibility.

Author : Friedrich Kragler,Martin Hülskamp
Publisher : Springer Science & Business Media
Page : 191 pages
File Size : 53,6 Mb
Release : 2011-12-06
Category : Science
ISBN : 9781441915313

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Short and Long Distance Signaling by Friedrich Kragler,Martin Hülskamp Pdf

The ability of plants to exchange RNA molecules and transcription factors between cells and tissues is a relatively recent discovery. However, all areas of research such as plant development, metabolism, and plant pathogen interactions now realize the importance of this phenomenon. In this book, experts from the field of intercellular transport deal with various aspects on intercellular transport of viruses and plant endogenous macromolecules such as transcription factors, small silencing-induced and micro RNAs, and other RNAs and their function as signals. The aim of the book is to provide the basic information on the cell-to-cell transport mechanism and to give an overview of the current knowledge of this relatively new field of research. To quote the words of W.J. Lucas “...pioneering discoveries in this field of cell-to-cell and long-distance signaling should certainly entice talented young scholars to join this frontier area of plant biology” . He is certainly right as we got only a first glimpse on the cellular factors regulating intercellular transport and the functional diversity of the ever-increasing number of proteins and RNA molecules found to move between cells.

Author : Peter Meyer
Publisher : John Wiley & Sons
Page : 304 pages
File Size : 48,8 Mb
Release : 2008-04-15
Category : Science
ISBN : 9781405173056

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Annual Plant Reviews, Plant Epigenetics by Peter Meyer Pdf

With the discovery of RNAi pathways and the histone code, epigenetics has become a popular and fast evolving research topic. Plant science has made a number of elementary contributions to this field, and the common elements of epigenetic systems have linked research groups interested in plant, fungal and animal systems. This volume provides a comprehensive overview epigenetic mechanisms and biological processes in plants, illustrating the wider relevance of this research to work in other plant science areas and on non-plant systems. It discusses recent advances in our knowledge of basic mechanisms and molecular components that control transcriptional and post-transcriptional silencing, an understanding of which is essential for plant researchers who use transgenic lines for stable expression of a recombinant construct or for targeted inactivation of an endogenous gene. These aspects should be of special interest to the agricultural industry. The volume illustrates the relevance of epigenetic control systems to gene regulation and plant development, examining paramutation, genomic imprinting and microRNA-based gene regulation mechanisms. Finally, it demonstrates the significance of epigenetic systems to viral defence and genome organisation. The volume is directed at researchers and professionals in plant molecular genetics, plant biochemistry and plant developmental biology.

Author : Sangita Sahni,Bishun Deo Prasad,Prasant Kumar
Publisher : CRC Press
Page : 356 pages
File Size : 51,7 Mb
Release : 2017-12-22
Category : Science
ISBN : 9781351819473

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Plant Biotechnology, Volume 2 by Sangita Sahni,Bishun Deo Prasad,Prasant Kumar Pdf

This volume is the second of the new two-volume Plant Biotechnology set. This volume covers many recent advances in the development of transgenic plants that have revolutionized our concepts of sustainable food production, cost-effective alternative energy strategies, microbial biofertilizers and biopesticides, and disease diagnostics through plant biotechnology. With the advancements in plant biotechnology, many of the customary approaches are out of date, and an understanding of new updated approaches is needed. This volume presents information related to recent methods of genetic transformation, gene silencing, development of transgenic crops, biosafety issues, microbial biotechnology, oxidative stress, and plant disease diagnostics and management. Key features: Provides an in-depth knowledge of various techniques of genetic transformation of plants, chloroplast, and fungus Describes advances in gene silencing in plants Discusses transgenic plants for various traits and their application in crop improvement Looks at genetically modified foods and biodiesel production Describes biotechnological approaches in horticultural and ornamental plants Explores the biosafety aspect associated with transgenic crops Considers the role of microbes in sustainable agriculture

Author : Jan Barciszewski
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 49,6 Mb
Release : 2003-08-31
Category : Science
ISBN : 0306478358

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Non-Coding RNAs by Jan Barciszewski Pdf

General inspection of a role performed in the cell by RNAs allows us to distinguish three major groups of transcripts: I. protein-coding mRNAs, II. non-coding housekeeping and III. regulatory RNAs. The housekeeping RNAs include RNA classes that are generally, constitutively expressed and whose presence is required for normal function and viability of the cells. On the other hand, a group of regulatory RNAs includes RNA species that are expressed at certain stages of organism development or cell differentiation or as a response to external stimuli and can affect expression of other genes on the levels of transcription or translation. Non-coding RNA transcripts form a heterogeneous class of RNAs that can not be characterized by a single specific function. Initially, the term non-coding RNA (ncRNA) was used primarily to describe polyadenylated and a capped eukaryotic RNAs transcribed by RNA polymerase II, but lacking long open reading frames. Now, this definition can be extended to cover all RNA transcripts that do not show protein-coding capacity and is sometimes used to describe any RNA that does not encode protein, including introns. This book is an in-depth look at the function of Non-Coding RNAs and their relationship to Molecular Biology and Molecular Biology.

Author : Susana Araújo,Pedro Fevereiro,Matthias Fladung,Bruno Mezzetti,Guy Smagghe,Jeremy Bruton Sweet
Publisher : Frontiers Media SA
Page : 103 pages
File Size : 42,9 Mb
Release : 2021-07-28
Category : Science
ISBN : 9782889711000

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Advances and Challenges of RNAi Based Technologies for Plants by Susana Araújo,Pedro Fevereiro,Matthias Fladung,Bruno Mezzetti,Guy Smagghe,Jeremy Bruton Sweet Pdf

Author : Zamir K. Punja,S. H. De Boer,Hélène Sanfaçon
Publisher : CABI
Page : 591 pages
File Size : 55,7 Mb
Release : 2007-01-01
Category : Science
ISBN : 9781845933104

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Biotechnology and Plant Disease Management by Zamir K. Punja,S. H. De Boer,Hélène Sanfaçon Pdf

As agricultural production increases to meet the demands of a growing world population, so has the pace of biotechnology research to combat plant disease. Diseases can be caused by a variety of complex plant pathogens including fungi, bacteria, viruses and nematodes, and their management requires the use of techniques in transgenic technology, biochemistry and genetics. While texts exist on specific pathogens or management practices, a comprehensive review is needed of recent developments in modern techniques and the understanding of how pathogens cause disease. This collection of studies discusses the key approaches to managing each group of pathogens within the context of recent developments in biotechnology. Broad themes include microbe-plant interactions, molecular diagnostics of plant pathogens and enhancing the resistance of plants.

Author : Bruno Mezzetti,Jeremy Bruton Sweet,Guy Smagghe,Elena Baraldi,Salvatore Arpaia,Antje Dietz-Pfeilstetter,Vera Ventura
Publisher : Frontiers Media SA
Page : 168 pages
File Size : 52,6 Mb
Release : 2022-08-04
Category : Science
ISBN : 9782889767175

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Advances and Challenges of RNAi Based Technologies for Plants - Volume 2 by Bruno Mezzetti,Jeremy Bruton Sweet,Guy Smagghe,Elena Baraldi,Salvatore Arpaia,Antje Dietz-Pfeilstetter,Vera Ventura Pdf