The Antimicrobial Drugs

Author : Eric M. Scholar Associate Professor of Pharmacology University of Nebraska College of Medicine,William B. Pratt Professor of Pharmacology University of Michigan Medical School
Publisher : Oxford University Press, USA
Page : 621 pages
File Size : 45,6 Mb
Release : 2000-05-22
Category : Medical
ISBN : 9780199759712

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The Antimicrobial Drugs by Eric M. Scholar Associate Professor of Pharmacology University of Nebraska College of Medicine,William B. Pratt Professor of Pharmacology University of Michigan Medical School Pdf

The is the third edition of a text that surveys the drugs used to treat bacterial, fungal, prarsitic, and viral infections. This book contains comprehensive presentations of the mechanisms for both the antimicrobial actions and for the adverse clinical effects of these drugs. Complete discussions of the pharmacology are highlighted by numerous charts and tables summarizing each drug's pharmacokinetic properties and microbial susceptibility. With 3500 reference citations, The Anitmicrobial Drugs provides a complete entry into the literature, making it an invaluable resource for infectious disease specialists, clinical pharmacists, clinical microbiologists, medical students, pharmacy students, and graduate students in pharmacology and microbiology.

Author : David Greenwood
Publisher : Oxford University Press
Page : 460 pages
File Size : 50,7 Mb
Release : 2008-02-21
Category : Medical
ISBN : 9780199534845

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Antimicrobial Drugs by David Greenwood Pdf

Between 1935 and 1944 the field of microbiology, and by implication medicine as a whole, underwent dramatic advancement. The discovery of the extraordinary antibacterial properties of sulphonamides, penicillin, and streptomycin triggered a frantic hunt for more antimicrobial drugs that was to yield an abundant harvest in a very short space of time. By the early 1960s more than 50 antibacterial agents were available to the prescribing physician and, largely by a process of chemicalmodification of existing compounds, that number has more than tripled today. We have become so used to the ready availability of these relatively safe and highly effective 'miracle drugs' that it is now hard to grasp how they transformed the treatment of infection.This book documents the progress made from the first tentative search for an elusive 'chemotherapy' of infection in the early days of the twentieth century, to the development of effective antiviral agents for the management of HIV as the millennium drew to a close. It also offers a celebration of the individuals and groups that made this miracle happen, as well as examining the inexorable rise of the global pharmaceutical industry, and, most intriguingly, the essential input of luck.Infection still maintains a high profile in both medicine and the media, with the current threats of 'superbugs' such as MRSA acquired in hospital, and a potential resistance to antibiotics. This book tracks the history of antimicrobial drugs, a remarkable medical triumph that has provided doctors with an amazing armoury of safe and effective drugs that ensure that reversion to the helpless state of the fight against infection witnessed in the early 1900s is extremely unlikely. This timelycompendium acknowledges the agents that have surely led to the relief of more human and animal suffering than any other class of drugs in the history of medical endeavour.

Author : Eric Michael Scholar,William B. Pratt
Publisher : Oxford University Press, USA
Page : 632 pages
File Size : 43,5 Mb
Release : 2000
Category : Anti
ISBN : 0195125282

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The Antimicrobial Drugs by Eric Michael Scholar,William B. Pratt Pdf

This is a thorough updating of a classic text that has been published in three editions since Pratt's Chemotherapy of Infection (OUP, 1973). Its treatment of the mechanisms of action, pharmacology and adverse effects of the drugs used to treat bacterial, fungal, parasitic and viral infectionshas been greatly expanded, and this edition includes two completely new chapters on the fluoroquinolones and the drugs used to treat AIDS. the frugs used to treat AIDS.

Author : National Research Council,Division on Earth and Life Studies,Division of Medical Sciences,Commission on Life Sciences,Committee to Study the Human Health Effects of Subtherapeutic Antibiotic Use in Animal Feeds
Publisher : National Academies Press
Page : 393 pages
File Size : 52,8 Mb
Release : 1980-02-01
Category : Medical
ISBN : 9780309030441

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The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds by National Research Council,Division on Earth and Life Studies,Division of Medical Sciences,Commission on Life Sciences,Committee to Study the Human Health Effects of Subtherapeutic Antibiotic Use in Animal Feeds Pdf

Author : Douglas L. Mayers,Jack D. Sobel,Marc Ouellette,Keith S. Kaye,Dror Marchaim
Publisher : Springer
Page : 773 pages
File Size : 40,8 Mb
Release : 2017-06-19
Category : Medical
ISBN : 9783319467184

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Antimicrobial Drug Resistance by Douglas L. Mayers,Jack D. Sobel,Marc Ouellette,Keith S. Kaye,Dror Marchaim Pdf

The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.

Author : Scott H. Podolsky
Publisher : JHU Press
Page : 324 pages
File Size : 47,6 Mb
Release : 2015-01-15
Category : Medical
ISBN : 9781421415932

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The Antibiotic Era by Scott H. Podolsky Pdf

During the post-World War II "wonder drug" revolution, antibiotics were viewed as a panacea for mastering infectious disease. This book narrates the far-reaching history of antibiotics, focusing particularly on reform efforts that attempted to fundamentally change how antibiotics are developed and prescribed

Author : T. J. Franklin,G. A. Snow
Publisher : Springer Science & Business Media
Page : 173 pages
File Size : 54,6 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781475745993

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Biochemistry and Molecular Biology of Antimicrobial Drug Action by T. J. Franklin,G. A. Snow Pdf

The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Author : Trevor J. Franklin,George Alan Snow
Publisher : Springer Science & Business Media
Page : 188 pages
File Size : 54,8 Mb
Release : 2006-10-31
Category : Medical
ISBN : 9780387275666

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Biochemistry and Molecular Biology of Antimicrobial Drug Action by Trevor J. Franklin,George Alan Snow Pdf

The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 722 pages
File Size : 41,8 Mb
Release : 2017-05-29
Category : Medical
ISBN : 9780323461511

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Nanostructures for Antimicrobial Therapy by Anton Ficai,Alexandru Mihai Grumezescu Pdf

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Author : Steeve Giguère,John F. Prescott,Patricia M. Dowling
Publisher : John Wiley & Sons
Page : 704 pages
File Size : 53,6 Mb
Release : 2013-07-25
Category : Medical
ISBN : 9781118675076

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Antimicrobial Therapy in Veterinary Medicine by Steeve Giguère,John F. Prescott,Patricia M. Dowling Pdf

The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy. Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.

Author : Paul H. Axelsen
Publisher : Springer Science & Business Media
Page : 156 pages
File Size : 48,6 Mb
Release : 2002
Category : Medical
ISBN : 0896038424

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Essentials of Antimicrobial Pharmacology by Paul H. Axelsen Pdf

For many medical students and physicians, the task of quickly obtaining sufficient, accurate, and up-to-date information about the pharmacology of antimicrobials often involves consulting either lengthy textbooks or inadequate tabular guides. In Essentials of Antimicrobial Pharmacology: A Guide to Fundamentals for Practice, Dr. Axelsen superbly addresses this problem by concisely summarizing the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrating their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. Background discussions explain the fundamentals of measuring antibiotic effect, administering antibiotics, distribution and elimination, sensitivity testing, and dose-response relationships. Essentials of Antimicrobial Pharmacology: A Guide to Fundamentals for Practice provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on New Directions in the Study of Antimicrobial Therapeutics: Immunomodulation,Committee on New Directions in the Study of Antimicrobial Therapeutics: New Classes of Antimicrobials
Publisher : National Academies Press
Page : 102 pages
File Size : 40,7 Mb
Release : 2006-01-03
Category : Medical
ISBN : 9780309180689

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Treating Infectious Diseases in a Microbial World by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on New Directions in the Study of Antimicrobial Therapeutics: Immunomodulation,Committee on New Directions in the Study of Antimicrobial Therapeutics: New Classes of Antimicrobials Pdf

Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Author : L. E. Bryan
Publisher : Unknown
Page : 608 pages
File Size : 52,5 Mb
Release : 1984
Category : Medical
ISBN : UOM:39015006697075

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Antimicrobial Drug Resistance by L. E. Bryan Pdf

Antimicrobial Drug Resistance presents information regarding the ability of organisms to resist natural and synthetically derived inhibitors. It presents the view of the authors who made significant contributions to the understanding of resistance. The book focuses on inhibitors classified as antifungal, antiviral, and antimalarial, as well as metal ions. It also covers numerous reactions, which have been genetically and biochemically analyzed in this context. Additionally, some chapters cover resistance plasmids of most of the clinically important bacteria. The book is designed to aid those ...

Author : William B. Pratt,F. Robert Fekety
Publisher : Oxford University Press, USA
Page : 501 pages
File Size : 52,9 Mb
Release : 1986
Category : Medical
ISBN : 0195035615

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The Antimicrobial Drugs by William B. Pratt,F. Robert Fekety Pdf

This reworking and expansion of Pratt's Chemotherapy of Infection has three new chapters. They cover antibiotic choice, therapy in office practice, and therapy for severe bacterial infections in hospitalized patients. There is also information on microbial susceptability, pharmacokinetic properties of the drugs in each class, and regimes of therapy. Over 3,000 references are included.

Author : José-Luis Capelo-Martínez,Gilberto Igrejas
Publisher : John Wiley & Sons
Page : 730 pages
File Size : 42,5 Mb
Release : 2019-09-24
Category : Medical
ISBN : 9781119282525

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Antibiotic Drug Resistance by José-Luis Capelo-Martínez,Gilberto Igrejas Pdf

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies