The Link Between Obesity And Cancer

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The Link Between Obesity and Cancer

Author : Raman Mehrzad
Publisher : Academic Press
Page : 302 pages
File Size : 52,8 Mb
Release : 2022-09-22
Category : Science
ISBN : 9780323909662

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The Link Between Obesity and Cancer by Raman Mehrzad Pdf

The Link between Obesity and Cancer provides a comprehensive review on the relationship between obesity and cancer, presenting global perspectives on obesity and cancer incidence that are followed by in-depth discussions on cancers for which we have new evidence of a causal relationship with obesity. Readers will gain fundamental knowledge on which cancer types are related to obesity. In addition, this updated resource provides significant knowledge for clinicians on when to act, along with specific management guidelines for patients, as well as how to understand potential risk factors and how to directly or indirectly minimize these risks. The book also provides never-before-published scientific data for any researcher in the field, identifying molecular mechanisms and links behind the development of malignancy and promoting research in new and effective target pathways in developing therapeutic strategies. Provides essential knowledge on how to understand the link between obesity and cancer and why and how this occurs Presents a significant knowledge base for clinicians on when to act, along with patient management guidelines for patients with obesity and potential risk factors Contains new scientific data and findings for researchers that identify the molecular mechanisms and links behind the development of malignancy

The Role of Obesity in Cancer Survival and Recurrence

Author : Institute of Medicine,Board on Health Care Services,National Cancer Policy Forum
Publisher : National Academies Press
Page : 126 pages
File Size : 40,7 Mb
Release : 2012-06-12
Category : Medical
ISBN : 9780309253369

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The Role of Obesity in Cancer Survival and Recurrence by Institute of Medicine,Board on Health Care Services,National Cancer Policy Forum Pdf

Recent research suggests that obesity and excess weight can play a prominent role in the incidence and progression of various cancers. Obesity results from an energy imbalance - that is, energy intake that is higher than energy expenditure - could also influence the growth of cancers. Recognizing the impact that current findings on obesity and cancer could have on future cancer prevention and care, the National Cancer policy Forum (NCPF) of the Institute of Medicine (IOM) help a 2-day workshop on "The Role of Obesity in Cancer Survival and Recurrence," in Washington, DC, on October 31 and November 1, 2011. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary reviews each presenter's latest clinical evidence on the obesity-cancer link and the molecular mechanisms that might explain that link. Clinicians, researchers, cancer survivors, and policy makers also discussed potential interventions to counter the effects of obesity on cancer, and research and policy measures needed to stem the rising tide of cancer mortality predicted by an increasingly overweight and older population worldwide. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary explores the complex web of molecular mechanisms that underlie the obesity-cancer link, the ways to design future studies to acquire the information needed to guide patient care, what to advise cancer patients about weight loss, diet, exercise, and other measures to reduce their risk of cancer progression or recurrence and policy suggestions related to research, education, and dissemination of the findings on obesity and cancer.

Obesity, Inflammation and Cancer

Author : Andrew J. Dannenberg,Nathan A. Berger
Publisher : Springer Science & Business Media
Page : 440 pages
File Size : 50,8 Mb
Release : 2013-05-21
Category : Medical
ISBN : 9781461468196

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Obesity, Inflammation and Cancer by Andrew J. Dannenberg,Nathan A. Berger Pdf

In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. This volume of Energy Balance and Cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. The volume first provides information on inflammation as an important link between obesity and insulin resistance, which is in itself linked to promotion of cancer through hyperinsulinemia. The volume then covers some of the most important mechanisms by which obesity leads to inflammation, including the novel inflammasome concept, alterations in chromatin structure, circulating inflammatory factors, unique cellular interactions between adipocytes and macrophages and the direct link of dietary fat to inflammation and cancer. Overall, this volume will provide important insight to help understand how inflammation may help modulate the linkage between obesity and cancer and serve as a platform for developing future research in this area.

Physical Activity and Cancer

Author : Kerry S. Courneya,Christine M. Friedenreich
Publisher : Springer Science & Business Media
Page : 389 pages
File Size : 49,8 Mb
Release : 2010-11-26
Category : Medical
ISBN : 9783642042317

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Physical Activity and Cancer by Kerry S. Courneya,Christine M. Friedenreich Pdf

This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.

Obesity and Cancer

Author : Tobias Pischon,Katharina Nimptsch
Publisher : Springer
Page : 258 pages
File Size : 51,8 Mb
Release : 2016-12-01
Category : Medical
ISBN : 9783319425429

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Obesity and Cancer by Tobias Pischon,Katharina Nimptsch Pdf

This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians.

Weight Control and Physical Activity

Author : Harri Vainio,Franca Bianchini
Publisher : IARC
Page : 346 pages
File Size : 50,6 Mb
Release : 2002
Category : Health & Fitness
ISBN : 928323006X

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Weight Control and Physical Activity by Harri Vainio,Franca Bianchini Pdf

Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.

The Role of Obesity in Cancer

Author : Isra Bakawasa
Publisher : GRIN Verlag
Page : 25 pages
File Size : 42,6 Mb
Release : 2015-01-19
Category : Science
ISBN : 9783656879145

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The Role of Obesity in Cancer by Isra Bakawasa Pdf

Research Paper (postgraduate) from the year 2014 in the subject Biology - Human Biology, grade: A, The Catholic University of America (Department of Biology), course: Biotechnology, language: English, abstract: Obesity is a known cause of cancer, with worldwide research and epidemiological studies supporting the relationship between obesity and cancer. Obesity can lead to a number of cancers, through cellular and metabolic changes in the body. Hyperinsulenimia, low levels of estrogens and Insulin like growth factor binding protein-3 (IGF-BP3) are among the major causes of cancers that result from obesity. In this study we aim at reviewing the metabolic changes that accompany obesity and cancer, the molecular mechanisms associated with obesity and cancer and finally the epidemiological significance of this relationship.

Dietary Phytochemicals

Author : Chukwuebuka Egbuna,Sadia Hassan
Publisher : Springer Nature
Page : 262 pages
File Size : 50,5 Mb
Release : 2021-08-20
Category : Science
ISBN : 9783030729998

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Dietary Phytochemicals by Chukwuebuka Egbuna,Sadia Hassan Pdf

This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as anti-diabetic, anti-cancer and anti-obesity agents and describe their mechanisms to regulate cell metabolism. Written by global team of experts, Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes describes the potentials of novel phytochemicals, their sources, and underlying mechanism of action. The chapters were drawn systematically and incorporated sequentially to facilitate proper understanding. This book is intended for nutritionists, physicians, medicinal chemists, drug developers in research and development, postgraduate students and scientists in area of nutrition and life sciences.

Explaining Divergent Levels of Longevity in High-Income Countries

Author : National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Panel on Understanding Divergent Trends in Longevity in High-Income Countries
Publisher : National Academies Press
Page : 194 pages
File Size : 51,6 Mb
Release : 2011-06-27
Category : Social Science
ISBN : 9780309217101

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Explaining Divergent Levels of Longevity in High-Income Countries by National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Panel on Understanding Divergent Trends in Longevity in High-Income Countries Pdf

During the last 25 years, life expectancy at age 50 in the United States has been rising, but at a slower pace than in many other high-income countries, such as Japan and Australia. This difference is particularly notable given that the United States spends more on health care than any other nation. Concerned about this divergence, the National Institute on Aging asked the National Research Council to examine evidence on its possible causes. According to Explaining Divergent Levels of Longevity in High-Income Countries, the nation's history of heavy smoking is a major reason why lifespans in the United States fall short of those in many other high-income nations. Evidence suggests that current obesity levels play a substantial part as well. The book reports that lack of universal access to health care in the U.S. also has increased mortality and reduced life expectancy, though this is a less significant factor for those over age 65 because of Medicare access. For the main causes of death at older ages -- cancer and cardiovascular disease -- available indicators do not suggest that the U.S. health care system is failing to prevent deaths that would be averted elsewhere. In fact, cancer detection and survival appear to be better in the U.S. than in most other high-income nations, and survival rates following a heart attack also are favorable. Explaining Divergent Levels of Longevity in High-Income Countries identifies many gaps in research. For instance, while lung cancer deaths are a reliable marker of the damage from smoking, no clear-cut marker exists for obesity, physical inactivity, social integration, or other risks considered in this book. Moreover, evaluation of these risk factors is based on observational studies, which -- unlike randomized controlled trials -- are subject to many biases.

The Surgeon General's Call to Action to Prevent and Decrease Overweight and Obesity

Author : Anonim
Publisher : Office of the Surgeon General
Page : 80 pages
File Size : 43,8 Mb
Release : 2001
Category : Health & Fitness
ISBN : UCLA:L0083580142

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The Surgeon General's Call to Action to Prevent and Decrease Overweight and Obesity by Anonim Pdf

Promotes the recognition, treatment, and prevention of conditions of overweight and obesity in the United States.

Eat for Life

Author : National Academy of Sciences,Institute of Medicine
Publisher : National Academies Press
Page : 190 pages
File Size : 53,8 Mb
Release : 1992-01-01
Category : Medical
ISBN : 9780309040495

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Eat for Life by National Academy of Sciences,Institute of Medicine Pdf

Results from the National Research Council's (NRC) landmark study Diet and health are readily accessible to nonscientists in this friendly, easy-to-read guide. Readers will find the heart of the book in the first chapter: the Food and Nutrition Board's nine-point dietary plan to reduce the risk of diet-related chronic illness. The nine points are presented as sensible guidelines that are easy to follow on a daily basis, without complicated measuring or calculatingâ€"and without sacrificing favorite foods. Eat for Life gives practical recommendations on foods to eat and in a "how-to" section provides tips on shopping (how to read food labels), cooking (how to turn a high-fat dish into a low-fat one), and eating out (how to read a menu with nutrition in mind). The volume explains what protein, fiber, cholesterol, and fats are and what foods contain them, and tells readers how to reduce their risk of chronic disease by modifying the types of food they eat. Each chronic disease is clearly defined, with information provided on its prevalence in the United States. Written for everyone concerned about how they can influence their health by what they eat, Eat for Life offers potentially lifesaving information in an understandable and persuasive way. Alternative Selection, Quality Paperback Book Club

Fulfilling the Potential of Cancer Prevention and Early Detection

Author : National Research Council,Institute of Medicine,National Cancer Policy Board
Publisher : National Academies Press
Page : 564 pages
File Size : 44,7 Mb
Release : 2003-05-07
Category : Medical
ISBN : 9780309170130

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Fulfilling the Potential of Cancer Prevention and Early Detection by National Research Council,Institute of Medicine,National Cancer Policy Board Pdf

Cancer ranks second only to heart disease as a leading cause of death in the United States, making it a tremendous burden in years of life lost, patient suffering, and economic costs. Fulfilling the Potential for Cancer Prevention and Early Detection reviews the proof that we can dramatically reduce cancer rates. The National Cancer Policy Board, part of the Institute of Medicine, outlines a national strategy to realize the promise of cancer prevention and early detection, including specific and wide-ranging recommendations. Offering a wealth of information and directly addressing major controversies, the book includes: A detailed look at how significantly cancer could be reduced through lifestyle changes, evaluating approaches used to alter eating, smoking, and exercise habits. An analysis of the intuitive notion that screening for cancer leads to improved health outcomes, including a discussion of screening methods, potential risks, and current recommendations. An examination of cancer prevention and control opportunities in primary health care delivery settings, including a review of interventions aimed at improving provider performance. Reviews of professional education and training programs, research trends and opportunities, and federal programs that support cancer prevention and early detection. This in-depth volume will be of interest to policy analysts, cancer and public health specialists, health care administrators and providers, researchers, insurers, medical journalists, and patient advocates.

Obesity and Diabetes

Author : Joel Faintuch,Salomão Faintuch
Publisher : Springer Nature
Page : 994 pages
File Size : 52,5 Mb
Release : 2020-12-14
Category : Medical
ISBN : 9783030533700

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Obesity and Diabetes by Joel Faintuch,Salomão Faintuch Pdf

Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians’ offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand. The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.

Energy Balance and Obesity

Author : Isabelle Romieu,Laure Dossus,William C. Willett
Publisher : IARC Working Group Report
Page : 0 pages
File Size : 45,8 Mb
Release : 2018-01-12
Category : Medical
ISBN : 9283225198

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Energy Balance and Obesity by Isabelle Romieu,Laure Dossus,William C. Willett Pdf

Understanding the relationship between energy balance and obesity is essential to develop effective prevention programs and policies. The International Agency for Research on Cancer convened a Working Group of world-leading experts in December 2015 to review the evidence regarding energy balance and obesity, with a focus on low- and middle-income countries, and to consider the following scientific questions: (i) Are the drivers of the obesity epidemic related only to energy excess and/or do specific foods or nutrients play a major role in this epidemic? (ii) What are the factors that modulate these associations? (iii) Which types of data and/or studies will further improve our understanding? This book provides summaries of the evidence from the literature as well as the Working Group's conclusions and recommendations to tackle the global epidemic of obesity.

Global Health Complications of Obesity

Author : Jahangir Moini,Raheleh Ahangari,Carrie Miller,Mohtashem Samsam
Publisher : Elsevier
Page : 482 pages
File Size : 50,5 Mb
Release : 2020-04-01
Category : Medical
ISBN : 9780128197523

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Global Health Complications of Obesity by Jahangir Moini,Raheleh Ahangari,Carrie Miller,Mohtashem Samsam Pdf

Global Health Complications of Obesity presents a valuable resource for research scientists and clinicians by covering the burden of obesity and related diseases and serving as a starting point for in-depth discussions in academic settings and for obesity-treatment specialists. Obesity is associated with a statistically higher risk of heart disease, hypertension, insulin resistance, type 2 diabetes and many other diseases. This succinct resource focuses on the current data, research and management of obesity. It is essential reading for healthcare professionals, endocrinologists, nutritionists, public health students and medical students. Presents clinical cases, key terms and targeted references Addresses diseases including diabetes, cancer, hypertension, osteoarthritis, fatty liver disease, infertility, renal failure and depression Provides a link to new knowledge that is ideal for both researchers and clinicians