Adrenomedullin

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Adrenomedullin

Author : Alfredo Martínez,Frank Cuttitta
Publisher : IOS Press
Page : 410 pages
File Size : 51,8 Mb
Release : 1998
Category : Adrenomedullin
ISBN : 9051993609

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Adrenomedullin by Alfredo Martínez,Frank Cuttitta Pdf

Adrenomedullin is a recently discovered peptide hormone which involved in many physiological and pathological processes. This book reviews all the information available on this intriguing molecule, covering topics as diverse as blood pressure regulation, growth of tumours and normal cells, the central nervous system, and comparative studies from sharks to mammals. An international group of experts has contributed to this volume which will be of interest to professionals, researchers, and those who will benefit from a broad review of the literature and the main trends in adrenomedullin research.

Adrenomedullin in Cardiovascular Disease

Author : Toshio Nishikimi
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 43,8 Mb
Release : 2005-04-28
Category : Medical
ISBN : 0387254048

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Adrenomedullin in Cardiovascular Disease by Toshio Nishikimi Pdf

Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has a role in the pathogenesis of arteriosclerosis. Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease. Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.

Innovative Medicine

Author : Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
Publisher : Springer
Page : 330 pages
File Size : 46,6 Mb
Release : 2015-10-13
Category : Science
ISBN : 9784431556510

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Innovative Medicine by Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto Pdf

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Cancer Research

Author : Anonim
Publisher : Unknown
Page : 1084 pages
File Size : 42,6 Mb
Release : 2007-03
Category : Cancer
ISBN : CORNELL:31924073494928

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Cancer Research by Anonim Pdf

Heart Failure

Author : Shigetake Sasayama,John Ross,Dirk L. Brutsaert
Publisher : Unknown
Page : 320 pages
File Size : 54,8 Mb
Release : 1996
Category : Heart failure
ISBN : UOM:39015062475762

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Heart Failure by Shigetake Sasayama,John Ross,Dirk L. Brutsaert Pdf

Neuroscience Letters

Author : Anonim
Publisher : Unknown
Page : 832 pages
File Size : 44,6 Mb
Release : 1998
Category : Neurology
ISBN : NWU:35557000113967

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Neuroscience Letters by Anonim Pdf

Chemical Abstracts

Author : Anonim
Publisher : Unknown
Page : 2540 pages
File Size : 41,8 Mb
Release : 2002
Category : Chemistry
ISBN : UOM:39015057321377

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Chemical Abstracts by Anonim Pdf

The Endocrine Pancreas and Regulation of Metabolism

Author : Anonim
Publisher : Unknown
Page : 1284 pages
File Size : 50,5 Mb
Release : 2001
Category : Endocrine glands
ISBN : UCSC:32106018177185

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The Endocrine Pancreas and Regulation of Metabolism by Anonim Pdf

This comprehensive and authoritative reference work examines the role of the endocrine pancreas in the regulation of fat, protein, and carbohydrate metabolism. The effects of hormones are broadly examined with emphasis on the gene, the cell and the organism as a whole. The functions of the pancreatic hormones in the integrated response of the body to various physiologic challenges are discussed. Following a general introduction by Sir Philip Randle, the book is divided into four sections:1. The Islets of Langerhans, 2. Target Tissues for Metabolic Regulatory Hormones, 3. Influence of Hormones Acting as Acute Metabolic Regulators on the Actions of Islet Hormones, and 4. Integrated Hormonal Responses to Physiological Challenges. The fourth part covers many interesting conditions such as pregnancy, aging, obesity, hypoglycemia, insulin-dependent diabetes mellitus, and starvation.

Adrenomedullin in Cardiovascular Disease

Author : Toshio Nishikimi
Publisher : Springer Science & Business Media
Page : 227 pages
File Size : 42,7 Mb
Release : 2005-07-25
Category : Medical
ISBN : 9780387254050

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Adrenomedullin in Cardiovascular Disease by Toshio Nishikimi Pdf

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

The Endocrine System

Author : P. Michael Conn,Leonard S. Jefferson,H. Maurice Goodman,Alan D. Cherrington,Jack L. Kostyo
Publisher : Unknown
Page : 1282 pages
File Size : 47,8 Mb
Release : 2001
Category : Endocrine glands
ISBN : 0195113268

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The Endocrine System by P. Michael Conn,Leonard S. Jefferson,H. Maurice Goodman,Alan D. Cherrington,Jack L. Kostyo Pdf

This comprehensive and authoritative reference work examines the role of the endocrine pancreas in the regulation of fat, protein, and carbohydrate metabolism. The effects of hormones are broadly examined with emphasis on the gene, the cell and the organism as a whole. The functions of the pancreatic hormones in the integrated response of the body to various physiologic challenges are discussed. Following a general introduction by Sir Philip Randle, the book is divided into four sections:1. The Islets of Langerhans, 2. Target Tissues for Metabolic Regulatory Hormones, 3. Influence of Hormones Acting as Acute Metabolic Regulators on the Actions of Islet Hormones, and 4. Integrated Hormonal Responses to Physiological Challenges. The fourth part covers many interesting conditions such as pregnancy, aging, obesity, hypoglycemia, insulin-dependent diabetes mellitus, and starvation.

Journal of the National Cancer Institute

Author : Anonim
Publisher : Unknown
Page : 516 pages
File Size : 42,8 Mb
Release : 2002
Category : Cancer
ISBN : NWU:35558004854127

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Journal of the National Cancer Institute by Anonim Pdf

"Summaries of papers" contained in the journal accompany each issue, 19--

European Journal of Endocrinology

Author : Anonim
Publisher : Unknown
Page : 472 pages
File Size : 41,6 Mb
Release : 2002
Category : Electronic
ISBN : NWU:35558004872806

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European Journal of Endocrinology by Anonim Pdf

Clinical Science

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 53,8 Mb
Release : 1979
Category : Biochemistry
ISBN : UCSD:31822018108308

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Clinical Science by Anonim Pdf

The Endothelium

Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
Page : 309 pages
File Size : 47,7 Mb
Release : 2011
Category : Science
ISBN : 9781615041237

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The Endothelium by Michel Félétou Pdf

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References