Biomimetic Radical Chemistry And Applications

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Biomimetic Radical Chemistry and Applications

Author : Chryssostomos Chatgilialoglu
Publisher : MDPI
Page : 300 pages
File Size : 46,6 Mb
Release : 2020-03-25
Category : Technology & Engineering
ISBN : 9783039283927

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Biomimetic Radical Chemistry and Applications by Chryssostomos Chatgilialoglu Pdf

The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having “free radicals” as a common denominator.

Biomimetic Radical Chemistry and Applications

Author : Chryssostomos Chatgilialoglu
Publisher : Unknown
Page : 300 pages
File Size : 40,5 Mb
Release : 2020
Category : Biology (General)
ISBN : 3039283936

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Biomimetic Radical Chemistry and Applications by Chryssostomos Chatgilialoglu Pdf

The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having “free radicals” as a common denominator.

Biomimetic Radical Chemistry and Applications 2021

Author : Chryssostomos Chatgilialoglu
Publisher : Mdpi AG
Page : 244 pages
File Size : 50,7 Mb
Release : 2022-05-19
Category : Science
ISBN : 3036543503

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Biomimetic Radical Chemistry and Applications 2021 by Chryssostomos Chatgilialoglu Pdf

The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment, suitably designed to be a similar as possible to cellular conditions. This Special Issue provides readers with a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to be used as traces for the discoveries of some relevant biological processes. Several subjects are presented, with five articles and five reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications and bioinspired synthesis, with "free radicals" as the common denominator.

Organosilanes in Radical Chemistry

Author : Chryssostomos Chatgilialoglu
Publisher : John Wiley & Sons
Page : 240 pages
File Size : 45,8 Mb
Release : 2004-04-02
Category : Science
ISBN : 9780470094259

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Organosilanes in Radical Chemistry by Chryssostomos Chatgilialoglu Pdf

In recent years silicon-centered radicals have played an important role in organic synthesis, polymer chemistry and material sciences. The aim of this book is to offer for the first time a description of silyl radicals within an interdisciplinary context, connecting structural characteristics and chemical properties to their application in different areas of chemistry. The first time different aspects of silyl radicals have been brought together Excellent reference tool for experienced practitioners of radical and/or silicon chemistry Presents various aspects of these intermediates in an original, comprehensive fashion This book is essential for anyone working in free radical and/or silicon chemistry as well as for those who want to approach these fields for the first time.

Biomimetics

Author : Amitava Mukherjee
Publisher : IntechOpen
Page : 544 pages
File Size : 41,7 Mb
Release : 2010-03-01
Category : Medical
ISBN : 9533070250

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Biomimetics by Amitava Mukherjee Pdf

Nature’s evolution has led to the introduction of highly efficient biological mechanisms. Imitating these mechanisms offers an enormous potential for the improvement of our day to day life. Ideally, by bio-inspiration we can get a better view of nature’s capability while studying its models and adapting it for our benefit. This book takes us into the interesting world of biomimetics and describes various arenas where the technology is applied. The 25 chapters covered in this book disclose recent advances and new ideas in promoting the mechanism and applications of biomimetics.

Biomimetic Chemistry: Radical Reactions in Vesicle Suspensions

Author : Chryssostomos Chatgilialoglu,Carla Ferreri
Publisher : Unknown
Page : 128 pages
File Size : 40,6 Mb
Release : 2010
Category : Electronic
ISBN : 9533070250

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Biomimetic Chemistry: Radical Reactions in Vesicle Suspensions by Chryssostomos Chatgilialoglu,Carla Ferreri Pdf

The chapter offered an overview of main processes studied by the membrane model of liposomes. The use of liposomes as carrier for drugs and active compound delivery cannot be forgotten, and some aspects of the liposome technology and reactivity shown in this chapter can have relevance also in this field. The system of monolamellar liposomes is expected to be extensively used for the examination of free radical reactivity, especially from a chemical biology approach exploring the biomimetic chemistry of radical species in detail, where the experimental set up of the liposomal model can satisfactorily represent the biological scenarios. In this context an improvement of interdisciplinarity is needed, among the fields of chemistry, biochemistry, biology and medicine, in order to create a common territory where the achievements of free radical reactivity can be straightforwardly transferred to a better comprehension of the biological pathways in health and diseases.

Ion-Radical Organic Chemistry

Author : Zory Vlad Todres
Publisher : CRC Press
Page : 464 pages
File Size : 53,5 Mb
Release : 2002-09-10
Category : Science
ISBN : 0824708105

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Ion-Radical Organic Chemistry by Zory Vlad Todres Pdf

Examining the formation, transformation, and application of ion radicals in typical conditions of organic synthesis, Organic Ion Radicals: Chemistry and Applications explains the reactions and principles of ion radical chemistry. The author addresses methods of determining ion- radical mechanisms and controlling ion radical reactions, issues relating to ecology and biology, and inorganic participants in ion radical organic reactions. Applications discussed include the roles of ion radicals in biological systems and their uses in optoelectronics, organic metals, and the manufacture of paper.

Robotics—Advances in Research and Application: 2013 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 552 pages
File Size : 48,7 Mb
Release : 2013-06-21
Category : Technology & Engineering
ISBN : 9781481692182

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Robotics—Advances in Research and Application: 2013 Edition by Anonim Pdf

Robotics—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Autonomous Robotics. The editors have built Robotics—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Autonomous Robotics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Robotics—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Membrane Lipidomics for Personalized Health

Author : Carla Ferreri,Chryssostomos Chatgilialoglu
Publisher : John Wiley & Sons
Page : 204 pages
File Size : 55,9 Mb
Release : 2015-08-31
Category : Science
ISBN : 9781118540411

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Membrane Lipidomics for Personalized Health by Carla Ferreri,Chryssostomos Chatgilialoglu Pdf

Lipidomics is an important aspect of personalized medicine in relation to nutrition and metabolism. This approach has become important due to the substantial presence of nutraceuticals in the market, since it gives personalized criteria on how to choose the right nutraceutical strategy for both prevention and for quality of life. This multi-disciplinary textbook uses a simple and practical approach to provide a comprehensive overview of lipidomics and their connection with health and nutrition. The text is divided into two parts: - Part 1 outlines the basics of lipidomics and focuses on the biochemical and nutritional aspects with descriptions of the analytical methods employed for the examination of cell membrane fatty acid composition. - Part 2 familiarizes the reader with the use of membrane lipidomic diagnostics in practical health care, using health conditions as examples to introduce the concept of lipidomic profiles in different physiological and pathological situations including prevention. Through the various properties of membrane lipidomics, readers will be able to combine the molecular status of the cell membrane with the evaluation of the subject for personalized nutritional and nutraceutical strategies. Membrane Lipidomics for Personalized Health will be beneficial to biologists, biochemists and medical researchers, as well as health care professionals, pharmacists, and nutritionists seeking in-depth information on the topic.

9th Congress on Electronic Structure: Principles and Applications (ESPA 2014)

Author : Manuel F. Ruiz-Lopez,Francisco J. Olivares del Valle
Publisher : Springer
Page : 232 pages
File Size : 41,8 Mb
Release : 2016-03-04
Category : Science
ISBN : 9783662492215

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9th Congress on Electronic Structure: Principles and Applications (ESPA 2014) by Manuel F. Ruiz-Lopez,Francisco J. Olivares del Valle Pdf

This volume collects research findings presented at the 9th Edition of the Electronic Structure: Principles and Applications (ESPA-2014) International Conference, held in Badajoz, Spain, on July 2–4, 2014. The contributions cover research work on theory, methods and foundations, materials science, structure and chemical reactivity as well as environmental effects and modelling. Originally published in the journal Theoretical Chemistry Accounts, these outstanding papers are now available in a hardcover print format, as well as a special electronic edition. This volume provides valuable content for all researchers in theoretical chemistry, and will especially benefit those research groups and libraries with limited access to the journal.

Streamlining Free Radical Green Chemistry

Author : V. Tamara Perchyonok,Ioannis Lykakis,Al Postigo
Publisher : Royal Society of Chemistry
Page : 804 pages
File Size : 53,9 Mb
Release : 2012
Category : Science
ISBN : 9781849733328

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Streamlining Free Radical Green Chemistry by V. Tamara Perchyonok,Ioannis Lykakis,Al Postigo Pdf

This practical, concise guide showcases the sustainable methods offered by green free radical chemistry and summarizes the fundamental science involved.

Non-covalent Interactions in the Synthesis and Design of New Compounds

Author : Abel M. Maharramov,Kamran T. Mahmudov,Maximilian N. Kopylovich,Armando J. L. Pombeiro
Publisher : John Wiley & Sons
Page : 477 pages
File Size : 45,9 Mb
Release : 2016-04-18
Category : Science
ISBN : 9781119109891

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Non-covalent Interactions in the Synthesis and Design of New Compounds by Abel M. Maharramov,Kamran T. Mahmudov,Maximilian N. Kopylovich,Armando J. L. Pombeiro Pdf

This book aims to overview the role of non-covalent interactions, such as hydrogen and halogen bonding, π-π, π-anion and electrostatic interactions, hydrophobic effects and van der Waals forces in the synthesis of organic and inorganic compounds, as well as in design of new crystals and function materials. The proposed book should allow to combine, in a systematic way, recent advances on the application of non-covalent interactions in synthesis and design of new compounds and functional materials with significance in Inorganic, Organic, Coordination, Organometallic, Pharmaceutical, Biological and Material Chemistries. Therefore, it should present a multi- and interdisciplinary character assuring a rather broad scope. We believe it will be of interest to a wide range of academic and research staff concerning the synthesis of new compounds, catalysis and materials. Each chapter will be written by authors who are well known experts in their respective fields.

Robotics—Advances in Research and Application: 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 582 pages
File Size : 42,7 Mb
Release : 2012-12-26
Category : Technology & Engineering
ISBN : 9781464992148

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Robotics—Advances in Research and Application: 2012 Edition by Anonim Pdf

Robotics—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Robotics. The editors have built Robotics—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Robotics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Robotics—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Stereoselective Synthesis of Drugs and Natural Products

Author : Vasyl Andrushko,Natalia Andrushko
Publisher : John Wiley & Sons
Page : 1836 pages
File Size : 53,5 Mb
Release : 2013-08-16
Category : Science
ISBN : 9781118628331

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Stereoselective Synthesis of Drugs and Natural Products by Vasyl Andrushko,Natalia Andrushko Pdf

Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Free Radicals in Synthesis and Biology

Author : F. Minisci
Publisher : Springer Science & Business Media
Page : 487 pages
File Size : 54,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400908970

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Free Radicals in Synthesis and Biology by F. Minisci Pdf

Free-radical reactions have been for long time the domain of the physical chemists and the basic chemical industry (polymerization of vinyl monomers, oxidation by molecular oxygen, chlorination of methane etc.), where the use of simple molecules and the possibility of partial conversions without heavy problems of product separations makes less dramatic the aspects of regio and chemoselectivity. As synonym of unselectivity, free radical reactions were considered of poor use in the synthesis of fine chemicals or sophisticated molecules, where a high selectivity is an essential condition for the success, or in the involvement of biological processes. Within the last 15 years, however, an authentic explosion of synthetic applications of free radical reactions occurred; they have gained a remarkable position among the selective methods of synthesis. At the same time the great importance of free radical reactions in fundamental biological processes and in the metabolism of drugs has been recognized. Thus a specialized meeting on these topics was generally felt appropriate. I had the honour and the onus to organize this workshop because for more than 30 years I have been involved in the research of free radical reactions. Thanks to a generous grant from NATO Scientific Affairs Division and the financial support of CNR and chemical industry (Montedison, Enichem, Zambon) such a meeting among almost 50 specialists and 15 observers of sufficient standard to take advantage of the discussion, became possible at Bardolino (Italy).