Phosphorylated Extracellular Matrix Proteins Of Bone And Dentin

Author : Michel Goldberg
Publisher : Bentham Science Publishers
Page : 464 pages
File Size : 52,8 Mb
Release : 2012-09-11
Category : Medical
ISBN : 9781608054657

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Phosphorylated Extracellular Matrix Proteins of Bone and Dentin by Michel Goldberg Pdf

Phosphorylated Extracellular Matrix Proteins of Bone and Dentin is the second volume of the e-book series Frontiers between Science and Clinic in Odontology. The phosphorylated proteins of the extracellular matrix of bone and teeth play a crucial structural role in the two tissues. They also act as signaling molecules. Phosphorylated extracellular matrix proteins have been implicated in nucleation and mineralization of skeletal tissues. This e-book covers research on these specific proteins, including details about the cells producing these molecules, their impact on bone and teeth pathology (osteogenesis and dentinogenesis imperfecta) and the potential of these molecules in promoting of inhibiting mineralization. This e-book also explains processes under the control of some enzymes - TNAP and metalloproteases (MMPs) - such as intracellular regulation in bone and dentine, splicing, respective roles of cleavage products, SIBLINGs, nucleation and crystal growth and regulation. This second volume serves as a valuable reference to practicing odontologists, biology and biomaterials scientists and tissue engineers interested in protein research related to tooth and bone formation.

Author : Michel Goldberg,Pamela Den Besten
Publisher : Springer Nature
Page : 305 pages
File Size : 45,8 Mb
Release : 2021-09-30
Category : Medical
ISBN : 9783030762834

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Extracellular Matrix Biomineralization of Dental Tissue Structures by Michel Goldberg,Pamela Den Besten Pdf

This book addresses the structural and biological properties of dental and peridental tissue structures and covers their mineralization process. The book contains a description of dentines, cementum, enamel and bone, including collagens, as well as non-collagenous proteins (SIBLINGs, SLRPs, GAGs, PGs, lipids, and MMPs). The mechanisms of mineralization are described in detail and the book is focused on matrix vesicles, collagen mineralization and the role of non-collagenous extracellular matrix components either as promoters or inhibitors of mineralization. In addition, the matrix components (non-collagenous) of enamel (amelogenin, ameloblastin, enamelin, MMP4, MMP20 and other proteases) are reviewed and their respective roles in dental tissues biomineralizations and tissue turnover are discussed. Additionally, environmental factors involved in enamel / dentin defects are adressed. With state-of-the-art contributions from experts in the respective domains, the book is a useful introduction to the field for junior scientists, interested in dental and peridental tissue biomineralization. It is also an interesting read for advanced scientists and clinicians working in dental research, giving them a broader view of the topic beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Author : Jerry W. Dillon
Publisher : Unknown
Page : 240 pages
File Size : 52,5 Mb
Release : 1997
Category : Dentin
ISBN : UOM:39015052436758

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Isolation and Characterization of the Organic Matrix Proteins of Peritubular Dentin by Jerry W. Dillon Pdf

Author : Hiromichi Nagasawa,Toshihiro Kogure,Kazuyoshi Endo
Publisher : Unknown
Page : 392 pages
File Size : 51,6 Mb
Release : 2020-10-09
Category : Medical
ISBN : 1013274415

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Biomineralization by Hiromichi Nagasawa,Toshihiro Kogure,Kazuyoshi Endo Pdf

This open access book is the proceedings of the 14th International Symposium on Biomineralization (BIOMIN XIV) held in 2017 at Tsukuba. Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of crystallization; and the function of organic matrices in biominerals, and this knowledge has been applied to dental, medical, pharmaceutical, materials, agricultural and environmental sciences and paleontology. As such, biomineralization is an important interdisciplinary research area, and further advances are expected in both fundamental and applied research. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Author : Gregory A Hudalla,William L Murphy
Publisher : Royal Society of Chemistry
Page : 422 pages
File Size : 42,9 Mb
Release : 2019-03-15
Category : Technology & Engineering
ISBN : 9781788018159

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Mimicking the Extracellular Matrix by Gregory A Hudalla,William L Murphy Pdf

The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research. Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical properties of the ECM, which outlines current knowledge of the ECM physical structure and reviewing state-of-the-art strategies to mimic its native microenvironments. The organisational characteristics of the ECM form the focus of another pair of chapters, where the collagen triple helix is discussed, followed by a review of advances in artificial reproduction of well-ordered systems using self-assembling peptides, or peptide amphiphiles. The balanced approach of this text gives it a broad appeal to those interested in the ECM from a range of backgrounds and disciplines. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.

Author : Anonim
Publisher : ScholarlyEditions
Page : 990 pages
File Size : 45,6 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781464991233

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Extracellular Matrix Proteins—Advances in Research and Application: 2012 Edition by Anonim Pdf

Extracellular Matrix Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Extracellular Matrix Proteins. The editors have built Extracellular Matrix Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Extracellular Matrix Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Extracellular Matrix Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : M. Rocha de Olivera Carrilho
Publisher : Karger Medical and Scientific Publishers
Page : 136 pages
File Size : 52,9 Mb
Release : 2017-10-19
Category : Medical
ISBN : 9783318061130

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Root Caries: From Prevalence to Therapy by M. Rocha de Olivera Carrilho Pdf

Case reports and clinical trials conducted in various countries show, more and more frequently, a positive correlation between the presence of original teeth and prevalence of root caries in older age. Because this is a global trend, it is likely that the predicted increase in the worldwide elderly population may soon cause a significant increase in the number of people requiring effective means of preventing and treating root surface caries. In response to this development, a team of outstanding contributors has reviewed the most important aspects of root caries. This new volume presents their findings along with discussions of how to deal with this health issue that progressively affects the oral health balance. The chapters in this book are divided in four core parts: Epidemiology, Biological Determinants, Lesion Assessment and Features and Preventive and Operative Therapies. The collection of state-of-the-art articles provides a broad overview and will serve as a reference for clinicians as well as scientists and, hopefully, will encourage new research.

Author : Albert Edward William Miles
Publisher : Unknown
Page : 554 pages
File Size : 47,6 Mb
Release : 1967
Category : Medical
ISBN : UOM:39015009878516

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Structural and Chemical Organization of Teeth by Albert Edward William Miles Pdf

Author : Sergey V. Dorozhkin
Publisher : CRC Press
Page : 850 pages
File Size : 51,5 Mb
Release : 2012-06-04
Category : Science
ISBN : 9789814364171

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Calcium Orthophosphates by Sergey V. Dorozhkin Pdf

Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophosphates. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. A comprehensive overview of calcium orthophosphates, this book highlights their importance and biomedical uses.

Author : Jasvir S. Khurana
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 55,6 Mb
Release : 2009-12-02
Category : Medical
ISBN : 9781597453479

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Bone Pathology by Jasvir S. Khurana Pdf

Bone Pathology is the second edition of the book, A Compendium of Skeletal Pathology that published 10 years ago. Similar to the prior edition, this book complements standard pathology texts and blends new but relatively established information on the molecular biology of the bone. Serving as a bench-side companion to the surgical pathologist, this new edition reflects new advances in our understanding of the molecular biology of bone. New chapters on soft-tissue sarcomas and soft-tissue tumors have been added as well as several additional chapters such as Soft-tissue pathology and Biomechanics. The volume is written by experts who are established in the field of musculoskeletal diseases. Bone Pathology is a combined effort from authors of different specialties including surgeons, pathologists, radiologists and basic scientists all of whom have in common an interest in bone diseases. It will be of great value to surgical pathology residents as well as practicing pathologists, skeletal radiologists, orthopedic surgeons and medical students.

Author : Agnes Bloch-Zupan,Heddie Sedano,Crispian Scully
Publisher : Elsevier
Page : 265 pages
File Size : 54,9 Mb
Release : 2012-03-21
Category : Medical
ISBN : 9780124160385

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Dento/Oro/Craniofacial Anomalies and Genetics by Agnes Bloch-Zupan,Heddie Sedano,Crispian Scully Pdf

Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research. Comprehensive examination of dento/oro/craniofacial anomalies Well-illustrated examples Presented in a compact, easy to use format

Author : Michel Goldberg
Publisher : Springer
Page : 282 pages
File Size : 49,8 Mb
Release : 2014-07-30
Category : Medical
ISBN : 9783642551604

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The Dental Pulp by Michel Goldberg Pdf

This book provides a detailed update on our knowledge of dental pulp and regenerative approaches to therapy. It is divided into three parts. The pulp components are first described, covering pulp cells, extracellular matrix, vascularization and innervation as well as pulp development and aging. The second part is devoted to pulp pathology and includes descriptions of the differences between reactionary and reparative dentin, the genetic alterations leading to dentinogenesis imperfecta and dentin dysplasia, the pulp reaction to dental materials, adverse impacts of bisphenol A and the effects of fluorosis, dioxin and other toxic agents. The final part of the book focuses on pulp repair and regeneration. It includes descriptions of various in vitro and in vivo (animal) experimental approaches, definition of the pulp stem cells with special focus on the stem cell niches, discussion of the regeneration of a living pulp and information on new strategies that induce pulp mineralization.

Author : Michel Goldberg
Publisher : Bentham Science Publishers
Page : 245 pages
File Size : 55,7 Mb
Release : 2010
Category : Medical
ISBN : 9781608051717

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Amelogenins: Multifaceted Proteins for Dental and Bone Formation and Repair by Michel Goldberg Pdf

"This volume is the 1st in a series of Ebooks that bridges the gap between advances in science and clinical practice in odontology. Recent advances in biology, materials science and tissue engineering are increasingly viewed as being of enormous clinical p"

Author : David Evered,Sara Harnett,Ciba Foundation
Publisher : John Wiley & Sons
Page : 328 pages
File Size : 43,6 Mb
Release : 1988-08-03
Category : Science
ISBN : UOM:39015013201150

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Cell and Molecular Biology of Vertebrate Hard Tissues by David Evered,Sara Harnett,Ciba Foundation Pdf

Brings together the latest research in the cellular and molecular biology of bones and teeth, including applications to medical and dental practice. An interdisciplinary group of contributors addresses control of bone formation, resorption and remodelling, osteoblast differentiation and osteoclast activity, factors influencing dental extracellular matrix biomineralization, non-collagen proteins in bone and their function, hormonal regulation of bone growth, and more.

Author : Brad W. Neville,Douglas D. Damm,Carl M. Allen,Angela C. Chi
Publisher : Elsevier Health Sciences
Page : 544 pages
File Size : 54,7 Mb
Release : 2018-09-26
Category : Medical
ISBN : 9780323582933

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Color Atlas of Oral and Maxillofacial Diseases - E-Book by Brad W. Neville,Douglas D. Damm,Carl M. Allen,Angela C. Chi Pdf

Introducing an essential new practical atlas for dental students and clinicians alike! The Color Atlas of Oral and Maxillofacial Diseases provides comprehensive, practical information on the most common oral and maxillofacial diseases and disorders. This new text uses a quick-access atlas format to help you easily look up clinical signs, diagnosis, and treatments. Nearly 750 high-quality images accompanied by brief narratives demonstrate exactly what clinical signs to look for – making an intervention as timely as possible. Written by four of the top dental authorities in the world, this concise resource is sure to become a clinical favorite. NEW! Quick-access atlas format makes it easy to look up clinical signs, diagnosis, and treatment of oral and maxillofacial diseases NEW! Nearly 750 high-quality radiographs and color clinical photos facilitate the identification of lesions and diseases. NEW! Comprehensive, focused coverage highlight diseases that may affect the oral and maxillofacial regions. NEW! Full-color design and illustrations. NEW! Logical organization reflects the sequence in which content is generally presented to predoctoral students