Role Of Exosomes In Biological Communication Systems

Role Of Exosomes In Biological Communication Systems Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Role Of Exosomes In Biological Communication Systems book. This book definitely worth reading, it is an incredibly well-written.

Role of Exosomes in Biological Communication Systems

Faisal A. Alzahrani,Islam M. Saadeldin
Role of Exosomes in Biological Communication Systems Book PDF

Author : Faisal A. Alzahrani,Islam M. Saadeldin
Publisher : Springer Nature
Page : 373 pages
File Size : 44,8 Mb
Release : 2020-11-20
Category : Medical
ISBN : 9789811565991

Get Book

Role of Exosomes in Biological Communication Systems by Faisal A. Alzahrani,Islam M. Saadeldin Pdf

This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.

Exosomes

Larry Edelstein,John R. Smythies,Peter J. Quesenberry,Denis Noble
Exosomes Book PDF

Author : Larry Edelstein,John R. Smythies,Peter J. Quesenberry,Denis Noble
Publisher : Academic Press
Page : 548 pages
File Size : 43,8 Mb
Release : 2019-10-16
Category : Science
ISBN : 9780128160541

Get Book

Exosomes by Larry Edelstein,John R. Smythies,Peter J. Quesenberry,Denis Noble Pdf

Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing

Mesenchymal Stem Cell Derived Exosomes

Yaoliang Tang,Buddhadeb Dawn
Mesenchymal Stem Cell Derived Exosomes Book PDF

Author : Yaoliang Tang,Buddhadeb Dawn
Publisher : Academic Press
Page : 288 pages
File Size : 40,9 Mb
Release : 2015-09-02
Category : Medical
ISBN : 9780128004975

Get Book

Mesenchymal Stem Cell Derived Exosomes by Yaoliang Tang,Buddhadeb Dawn Pdf

Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Exosomes in Cardiovascular Diseases

Junjie Xiao,Sanda Cretoiu
Exosomes in Cardiovascular Diseases Book PDF

Author : Junjie Xiao,Sanda Cretoiu
Publisher : Springer
Page : 307 pages
File Size : 51,8 Mb
Release : 2017-09-19
Category : Science
ISBN : 9789811043970

Get Book

Exosomes in Cardiovascular Diseases by Junjie Xiao,Sanda Cretoiu Pdf

The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.

Diagnostic and Therapeutic Applications of Exosomes in Cancer

Mansoor M. Amiji,Rajagopal Ramesh
Diagnostic and Therapeutic Applications of Exosomes in Cancer Book PDF

Author : Mansoor M. Amiji,Rajagopal Ramesh
Publisher : Academic Press
Page : 0 pages
File Size : 42,7 Mb
Release : 2018-05-11
Category : Medical
ISBN : 0128127740

Get Book

Diagnostic and Therapeutic Applications of Exosomes in Cancer by Mansoor M. Amiji,Rajagopal Ramesh Pdf

Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.

Exosomes and Microvesicles

Andrew F Hill
Exosomes and Microvesicles Book PDF

Author : Andrew F Hill
Publisher : Humana
Page : 0 pages
File Size : 42,5 Mb
Release : 2016-12-10
Category : Science
ISBN : 1493967266

Get Book

Exosomes and Microvesicles by Andrew F Hill Pdf

This volume covers methods for the analysis of extracellular vesicles (EV) that can be applied to isolated EVs from a wide variety of sources. This includes the use of electron microscopy, tunable resistance pulse sensing, and nanoparticle tracking analysis. The chapters in this book discuss EV cargoes containing proteins and genomic materials using a number of different approaches, and isolating EVs from platelets and neuronal cells and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and comprehensive, Exosomes and Microvesicles: Methods and Protocols is a valuable resource containing methodologies for anyone interested in researching EVs.

Extracellular Vesicles and Their Importance in Human Health

Ana Gil De Bona,Jose Antonio Reales-Calderon
Extracellular Vesicles and Their Importance in Human Health Book PDF

Author : Ana Gil De Bona,Jose Antonio Reales-Calderon
Publisher : BoD – Books on Demand
Page : 172 pages
File Size : 45,7 Mb
Release : 2020-03-04
Category : Science
ISBN : 9781789239430

Get Book

Extracellular Vesicles and Their Importance in Human Health by Ana Gil De Bona,Jose Antonio Reales-Calderon Pdf

Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.

Metabolomics Perspectives

Jacopo Troisi
Metabolomics Perspectives Book PDF

Author : Jacopo Troisi
Publisher : Academic Press
Page : 685 pages
File Size : 45,6 Mb
Release : 2022-03-15
Category : Science
ISBN : 9780323850636

Get Book

Metabolomics Perspectives by Jacopo Troisi Pdf

Metabolomics Perspectives: From Theory to Practical Application is an expertly written volume, which provides a thorough description of the current state-of-the-art in the metabolomics field. The philosophy behind the book is to guide the reader in a step-by-step exploration of metabolomics experiments, ranging from sample preparation to data extraction, analysis and interpretation, and to discuss the main current applications and future perspectives of this emerging science. Armed with critical insights, coupled with a clear writing, the book consists of three main sections. The first one introduces the pivotal theoretical fundamentals and provides a comprehensive overview of the "wet" laboratory workflow, including protocol instructions and a detailed description of experimental methods and analytical techniques. The second section covers a wide range of topics in the context of data analysis, including guidance in exploratory analysis, supervised and unsupervised machine learning approaches and validation and optimization methods. In addition to the several examples reported in the text, the book features an R package, specifically designed to perform all the described algorithms, which is hosted on a companion website (www.metabolomicsperspectives.com) together with several sets of available metabolomic data. Finally, an extensive dissertation describes the latest advances and the major fields of interest for metabolomics applications, highlighting their crucial potentials for future biomedical research. Thus, this book represents a must-read for both experienced researchers, interested in metabolomics, and newcomers to the field. Provides an in-depth description of the metabolomics experimental workflow and its applications in life science and biomedical research Features chapter contributions from the greatest international experts in the field Includes an R package and several sets of metabolomics data, hosted on a companion website

Extracellular Vesicles

Anonim
Extracellular Vesicles Book PDF

Author : Anonim
Publisher : Academic Press
Page : 314 pages
File Size : 40,9 Mb
Release : 2020-11-08
Category : Science
ISBN : 9780128206621

Get Book

Extracellular Vesicles by Anonim Pdf

Extracellular Vesicles, Volume 645 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Genetic labeling of extracellular vesicle exosomes for studying biogenesis and uptake in living mammalian cells, Fluorescent Labeling of Extracellular Vesicles, Isolation of extracellular vesicles from lymph, Transgenic rats for tracking body fluid/tissue-derived extracellular vesicles, Isolation of amniotic extracellular vesicles, Urinary extracellular vesicle isolation, Immunocapture-based ELISA to Characterize and Quantify Extracellular Vesicles in Both Cell Culture Supernatants and Body Fluids, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Bacterial Degradation of Organic and Inorganic Materials

Marziale Milani,Roberta Curia,Natalia Vladimirovna Shevlyagina,Francesco Tatti
Bacterial Degradation of Organic and Inorganic Materials Book PDF

Author : Marziale Milani,Roberta Curia,Natalia Vladimirovna Shevlyagina,Francesco Tatti
Publisher : Springer Nature
Page : 242 pages
File Size : 48,5 Mb
Release : 2023-05-22
Category : Medical
ISBN : 9783031269493

Get Book

Bacterial Degradation of Organic and Inorganic Materials by Marziale Milani,Roberta Curia,Natalia Vladimirovna Shevlyagina,Francesco Tatti Pdf

This interdisciplinary work deals with the bacterial degradation of organic and inorganic materials such as prosthetic devices and the consequent production of non-engineered nanoparticles (NPs). Focus is put on the interaction of these, often toxic, NPs with the environment, the microorganisms and the host human body. Electron Microscopy is the method of choice to investigate bacterial colonization and degradation of plastic polymers. Hence one section of the book is fully dedicated to the most recent and interesting microscopy technologies in microbiology and soft matters. The final chapter of the book on the complex and multivariate relationships between a microscopist and electron microscopy images is dedicated to Lyubov Vasilievna Didenko (1958 – 2015), a passionate researcher who contributed substantially to the field of Electron Microscopy research and its applications in studying bacterial-polymer interactions. The book addresses researchers and advanced students working in general and clinical microbiology, nanobiology, materials sciences and image analysis fields.

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases

Jin Wang
Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases Book PDF

Author : Jin Wang
Publisher : BoD – Books on Demand
Page : 194 pages
File Size : 47,5 Mb
Release : 2017-07-12
Category : Medical
ISBN : 9789535133353

Get Book

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases by Jin Wang Pdf

The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases.

Tumors of the Central Nervous System, Volume 11

M.A. Hayat
Tumors of the Central Nervous System Volume 11 Book PDF

Author : M.A. Hayat
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 52,5 Mb
Release : 2013-08-20
Category : Medical
ISBN : 9789400770379

Get Book

Tumors of the Central Nervous System, Volume 11 by M.A. Hayat Pdf

Like the ten preceding volumes in the series Tumors of the Central Nervous System, this book is distinguished for its comprehensive approach, its distinguished roster of some 93 contributors representing 8 different countries and its embrace of leading-edge technology and methods. Volume 11: Imaging, Glioma and Glioblastoma, Stereotactic Radiotherapy, Spinal Cord Tumors, Meningioma, and Schwannomas concentrates on the diagnosis, prognosis and therapy of four types of tumors, namely Glioblastoma, Meningioma, Schwannoma and Spinal Tumors. The book offers an in-depth survey of a range of new technologies and their applications to tumor diagnosis, treatment and therapy assessment. The contributors explain in thorough detail a range of current and newly developed imaging methods, including molecular imaging and PET scan. Also covered is molecular profiling of brain tumors to select therapy in clinical trials of brain tumors. Discussion includes a review of such surgical treatments as resection and the application of non-invasive stereotactic radiosurgery for treating high-risk patients with brain metastasis. Additional discussion is devoted to tumor seeding.

Supramolecules in Drug Discovery and Drug Delivery

Thomas Mavromoustakos,Andreas G. Tzakos,Serdar Durdagi
Supramolecules in Drug Discovery and Drug Delivery Book PDF

Author : Thomas Mavromoustakos,Andreas G. Tzakos,Serdar Durdagi
Publisher : Humana
Page : 0 pages
File Size : 54,6 Mb
Release : 2020-10-29
Category : Science
ISBN : 107160919X

Get Book

Supramolecules in Drug Discovery and Drug Delivery by Thomas Mavromoustakos,Andreas G. Tzakos,Serdar Durdagi Pdf

This detailed book aims to provide readers with critical information to accomplish the synthesis of nanosystems for the purpose of supramolecular entities complexing with drugs, targeted drug delivery system characterization, as well as the study of the physical-chemical interactions that govern the stability and properties of these systems. Beginning with a collection of chapters on drug delivery platforms such as cyclodextrins, micelles, liposomes, polymeric, nanotubes, and more, the volume continues with coverage of the study of nanotechnology systems using different biophysical techniques such as DSC, ITC, solid and liquid NMR spectroscopy, and electrochemistry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Supramolecules in Drug Discovery and Drug Delivery: Methods and Protocols serves as an ideal guide for researchers working toward drug delivery mechanisms that can tailor their physical chemical properties and enhance their efficacy, while retaining their structures intact.

Osteogenesis and Bone Regeneration

Haisheng Yang
Osteogenesis and Bone Regeneration Book PDF

Author : Haisheng Yang
Publisher : BoD – Books on Demand
Page : 143 pages
File Size : 47,8 Mb
Release : 2019-04-24
Category : Medical
ISBN : 9781789857672

Get Book

Osteogenesis and Bone Regeneration by Haisheng Yang Pdf

Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis.

Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology

Denis Corbeil
Prominin 1 CD133 New Insights on Stem Cancer Stem Cell Biology Book PDF

Author : Denis Corbeil
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 43,8 Mb
Release : 2012-11-19
Category : Medical
ISBN : 9781461458944

Get Book

Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology by Denis Corbeil Pdf

​​​​​​​Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.